4,394 results match your criteria fascioliasis


[Progress of researches on and fascioliasis in Yunnan Province].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2020 Jul;33(3):317-319

Department of Pathogenic Biology and Immunology, Kunming Medical University, Kunming 650500, China.

Fascioliasis is a zoonotic parasitic disease that seriously endangers human health and hinders socioeconomic development. mainly infects ruminants, such as cattle and sheep. However, there has recently been a rise in the number of human cases with fascioliasis with the improvements of diagnostic techniques. Read More

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Hepatic parasitic abscess resistant to traditional anthelmintics: difficulty of diagnosis and treatment of fascioliasis in the USA.

BMJ Case Rep 2021 Jul 20;14(7). Epub 2021 Jul 20.

Radiology, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA

We report a case of human fascioliasis in the USA that encountered many diagnostic uncertainties. Numerous tests available for detection of fascioliasis were utilised but the diagnosis remained elusive. Confounders included three negative stool ova and parasite examinations, positive hepatitis A virus IgM antibody, cross-reactive false-positive IgG antibody, absence of characteristic image findings and unrevealing liver biopsy. Read More

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A Comparison of the Risk for Chronic Fascioliasis between Children 3 to 5 Years and Children 6 to 12 Years of Age in the Cusco Region of Peru.

Am J Trop Med Hyg 2021 Jul 19. Epub 2021 Jul 19.

Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas.

School-age children bear the highest burden of fascioliasis in endemic countries. Few studies have addressed Fasciola in preschool children. We performed a secondary data analysis using two Fasciola databases from Cusco, Peru, comparing preschoolers with elementary school children. Read More

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Efficacy of triclabendazole and albendazole against Fasciola spp. infection in cattle in Côte d'Ivoire: a randomised blinded trial.

Acta Trop 2021 Jul 9;222:106039. Epub 2021 Jul 9.

Swiss Tropical and Public Health Institute, P.O. Box, CH-4002 Basel, Switzerland; University of Basel, P.O. Box, CH-4003 Basel, Switzerland.

Triclabendazole is the anthelminthic of choice for the treatment of fascioliasis, however, it is only registered in a few countries. We investigated the efficacy of a single-dose of triclabendazole (12 mg/kg) or albendazole (15 mg/kg) against Fasciola spp. infection in cattle on farms in the northern part of Côte d'Ivoire in a randomized clinical trial. Read More

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Fascioliasis Presenting With Migrating Liver Masses.

Am J Trop Med Hyg 2021 Jul 12. Epub 2021 Jul 12.

2Department of Pathology, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.

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Plasma cytokines during acute human fascioliasis.

Parasitol Res 2021 Jul 10. Epub 2021 Jul 10.

Instituto de Medicina Tropical "Alexander Von Humboldt" and Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Lima, Peru.

Fascioliasis is a foodborne trematode endemic worldwide. Children under 15 years have the highest prevalence of infection. We hypothesized that acute fascioliasis would be associated with more pronounced cytokine changes than in chronic disease or no helminth infections. Read More

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Scoping review of Neglected Tropical Disease Interventions and Health Promotion: A framework for successful NTD interventions as evidenced by the literature.

PLoS Negl Trop Dis 2021 Jul 6;15(7):e0009278. Epub 2021 Jul 6.

Global Health and Infection Department, Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom.

Background: Neglected Tropical Diseases (NTDs) affect more than one billion people globally. A Public Library of Science (PLOS) journal dedicated to NTDs lists almost forty NTDs, while the WHO prioritises twenty NTDs. A person can be affected by more than one disease at the same time from a range of infectious and non-infectious agents. Read More

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Detection of Fasciola Hepatica in Lori Sheep Using Polymerase Chain Reaction and Conventional Diagnostic Methods in Western Iran.

Arch Razi Inst 2021 Jul 1;76(2):223-229. Epub 2021 Jul 1.

Department of Biotechnology, Faculty of Basic Sciences, Ahvaz Azad University, Ahvaz, Iran.

Fascioliasis is an emerging and important food and water-borne disease in human communities which has become one of the most important health challenges in countries, like Iran. It causes weight loss, a decrease in feed conversion ratio as well as milk and meat production, and also reduces fertility in animals the prevalence of fasciolosis is increasing in some regions of the world due to various factors. Different methods have been used for the detection of Fasciola hepatica in animals. Read More

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Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update.

Korean J Parasitol 2021 Jun 21;59(3):189-225. Epub 2021 Jun 21.

Department of Environmental Medical Biology, Chung-Ang University College of Medicine, Seoul 06974, Korea.

The use of albendazole and mebendazole, i.e., benzimidazole broad-spectrum anthelmintics, in treatment of parasitic infections, as well as cancers, is briefly reviewed. Read More

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Biliary of Fascioliasis in Kermanshah Province, Western Iran.

Iran J Public Health 2021 Jan;50(1):215-216

Department of Medical Parasitology and Mycology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.

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January 2021

Emerging Cases of Fascioliasis in Lorestan Province, Western Iran: Case Series Report.

Iran J Public Health 2021 Jan;50(1):195-200

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Fascioliasis is a zoonotic disease caused by spp. We report five serologically and molecularly confirmed cases in an emerging region in Iran. A retrospective, case series study, performed in Lorestan Province, west of Iran between January 2015 and June 2016. Read More

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January 2021

Imaging findings of human hepatic fascioliasis: a case report and review of the literature.

J Med Case Rep 2021 Jun 24;15(1):324. Epub 2021 Jun 24.

Department of Radiology, Tehran University of Medical Sciences (TUMS), Tehran, Iran.

Background: Fascioliasis is a food-borne hepatobiliary zoonosis caused by Fasciola hepatica and Fasciola gigantica. Human infestations are predominantly seen in developing countries where the disease is endemic, but, due to the increase in international travel rates, hepatic fascioliasis is also appearing in nonendemic areas including Europe and the USA. The clinical and laboratory findings are usually nonspecific. Read More

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Stunting in pre-school and school-age children in the Peruvian highlands and its association with Fasciola infection and demographic factors.

PLoS Negl Trop Dis 2021 Jun 21;15(6):e0009519. Epub 2021 Jun 21.

Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America.

Fascioliasis is a zoonotic trematode infection that is endemic in the highlands of Peru. Chronic fascioliasis can be asymptomatic and remain undiagnosed for years. Chronic malnutrition in children, as manifested by stunting, leads to delayed cognitive development and lost productivity. Read More

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Triclabendazole Treatment Failure for Fasciola hepatica Infection among Preschool and School-Age Children, Cusco, Peru.

Emerg Infect Dis 2021 07;27(7):1850-1857

We conducted a retrospective cohort study of children who had chronic fascioliasis in the highlands of Peru to determine triclabendazole treatment efficacy. Children passing Fasciola eggs in stool were offered directly observed triclabendazole treatment (>1 doses of 10 mg/kg). Parasitologic cure was evaluated by using microscopy of stool 1-4 months after each treatment. Read More

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Comparison of Liver Condemnation and Bile Microscopy As Tools to Estimate Prevalence and Burden in the Anta Province of Cusco in Peru.

Vector Borne Zoonotic Dis 2021 Jun 14. Epub 2021 Jun 14.

Division of Infectious Disease, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.

Fascioliasis is a zoonotic infection linked to significant economic losses in the livestock industry. Infection prevalence and estimated financial burden vary across locations owing to different diagnostic tests used. The accuracy of liver condemnation to estimate the prevalence and costs of fascioliasis has seldom been evaluated. Read More

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One Health initiative in the Bolivian Altiplano human fascioliasis hyperendemic area: Lymnaeid biology, population dynamics, microecology and climatic factor influences.

Rev Bras Parasitol Vet 2021 28;30(2):e025620. Epub 2021 May 28.

Departamento de Parasitologia, Facultad de Farmacia, Universidad de Valencia, Valencia, Spain.

Fascioliasis is a freshwater snail-borne zoonotic disease. The Northern Bolivian Altiplano is a very high altitude endemic area where the highest human prevalences and intensities have been reported. Preventive chemotherapy by treatment campaigns is yearly applied. Read More

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Molecular confirmation of Fasciola hepatica infection in capybaras (Hydrochoerus hydrochaeris) from the state of Espírito Santo, Brazil.

Rev Bras Parasitol Vet 2021 28;30(2):e000221. Epub 2021 May 28.

Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.

Sixty-two fecal samples of capybara (Hydrochoerus hydrochaeris) living in eight conservation units (CUs) across the state of Espírito Santo, southeastern Brazil, were assessed for the presence of eggs of liver flukes via sedimentation. Fasciola hepatica eggs were found in 37.1% (23/62) of the samples. Read More

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Spread of the fascioliasis endemic area assessed by seasonal follow-up of rDNA ITS-2 sequenced lymnaeid populations in Cajamarca, Peru.

One Health 2021 Dec 11;13:100265. Epub 2021 May 11.

Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicente Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.

Fascioliasis is a worldwide emerging snail-borne zoonotic trematodiasis with a great spreading capacity linked to animal and human movements, climate change, and anthropogenic modifications of freshwater environments. South America is the continent with more human endemic areas caused by , mainly in high altitude areas of Andean regions. The Peruvian Cajamarca area presents the highest human prevalences reported, only lower than those in the Bolivian Altiplano. Read More

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December 2021

Autonomous Non Antioxidant Roles for Secreted Thioredoxin-1 and Peroxiredoxin-1.

Front Cell Infect Microbiol 2021 5;11:667272. Epub 2021 May 5.

Molecular Parasitology Laboratory, Centre of One Health (COH), Ryan Institute, National University of Ireland, Galway, Ireland.

Trematode parasites of the genus are the cause of liver fluke disease (fasciolosis) in humans and their livestock. Infection of the host involves invasion through the intestinal wall followed by migration in the liver that results in extensive damage, before the parasite settles as a mature egg-laying adult in the bile ducts. Genomic and transcriptomic studies revealed that increased metabolic stress during the rapid growth and development of is balanced with the up-regulation of the thiol-independent antioxidant system. Read More

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Genetic characterization and phylogenetic analysis of Fasciola species based on ITS2 gene sequence, with first molecular evidence of intermediate Fasciola from water buffaloes in Aswan, Egypt.

Ann Parasitol 2021 ;67(1):55-65

Department of Parasitology, Faculty of Veterinary Medicine, South Valley University, 83523 Qena, Egypt.

Fasciolosis is an important food and water-borne parasitic infection caused by the two trematode species, Fasciola hepatica, and F. gigantica. The present study aimed to identify the phenotypic features and genetic characterization of adult fasciolid that infecting buffaloes were studied in Aswan, Egypt. Read More

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Buffalo Infection by Fasciola gigantica Transmitted by Radix acuminata in Uttar Pradesh, India: A Molecular Tool to Improve Snail Vector Epidemiology Assessments and Control Surveillance.

Acta Parasitol 2021 May 21. Epub 2021 May 21.

Human Genetics Laboratory, Department of Biosciences, Central University Jamia Millia Islamia, New Delhi, 110025, India.

Purpose: Fascioliasis is caused by Fasciola species transmitted by freshwater Lymnaeidae snails and infecting herbivorous mammals and humans worldwide. In southern Asia, fascioliasis is a problem in livestock from the Near East to Bangladesh, where recent human infection reports are worrying. In this region, Fasciola gigantica is transmitted by species of the Radix auricularia superspecies group. Read More

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Domestic pig prioritized in one health action against fascioliasis in human endemic areas: Experimental assessment of transmission capacity and epidemiological evaluation of reservoir role.

One Health 2021 Dec 16;13:100249. Epub 2021 Apr 16.

Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain.

The Northern Bolivian Altiplano is the human fascioliasis hyperendemic area where the highest prevalences and intensities in humans have been reported. Preventive chemotherapy was implemented in the last ten years. Surveillance showed high human infection and re-infection rates in between the annual triclabendazole monodose treatments. Read More

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December 2021

Prevalence and factors associated with intestinal schistosomiasis and human fascioliasis among school children in Amhara Regional State, Ethiopia.

Trop Med Health 2021 May 11;49(1):35. Epub 2021 May 11.

Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.

Background: Schistosomiasis and fascioliasis are digenean parasitic infections and are among the neglected tropical diseases that have both medical and veterinary importance. They are found mainly in areas having limited access to safe water supply and improved sanitation.

Methods: A cross-sectional study was conducted to determine the prevalence of Schistosoma mansoni and Fasciola species infections and to identify associated risk factors among school children in Amhara Regional State, Ethiopia. Read More

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The First Report of Ruminant Fascioliasis in Sabah, East Malaysia.

J Parasitol Res 2021 16;2021:6691483. Epub 2021 Apr 16.

Department of Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang Selangor, Malaysia.

Ruminant fascioliasis is a neglected yet important tropical zoonotic disease that affects both the livestock and humans. The disease has a worldwide distribution, and Malaysia is one of the countries that face problems related to this parasite. These retrospective studies were conducted in Makmal Diagnosa Veterinar Kota Kinabalu (MDVKK) and Sabah Meat Technology Centre (SMTC), Kinarut over a period of eleven years (2008-2018). Read More

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Evaluation of zoonotic platyhelminthe infections identified in slaughtered livestock in Iran, 2015-2019.

BMC Vet Res 2021 May 5;17(1):185. Epub 2021 May 5.

Department of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Platyhelminth infections of livestock can result in considerable economic losses. This study aims to evaluate the spatial frequency of cystic echinococcosis (CE), dicrocoeliasis, and fascioliasis in livestock slaughtered in Iran during the years 2015-2019 and estimate direct costs associated with organ condemnation due to these parasites.

Methods: Abattoir data from 413 abattoirs representing all 31 Iranian provinces were collected from the Iran Veterinary Organization. Read More

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Evaluation of two Fasciola hepatica faecal egg counting protocols in sheep and cattle.

Vet Parasitol 2021 Jun 27;294:109435. Epub 2021 Apr 27.

Institute of Biological, Environmental & Rural Sciences, Aberystwyth University, Penglais Campus, Aberystwyth, Ceredigion, SY23 3FG, United Kingdom.

Fascioliasis causes significant economic losses and is a constant challenge to livestock farmers globally. Fluke faecal egg counts (flukeFECs) are a simple, non-invasive method used to detect the presence of patent liver fluke infection. Many flukeFEC techniques exist but they vary in complexity, precision and accuracy. Read More

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Fasciola hepatica Infection Risk for Adult Household Members with Children with Fascioliasis in Cusco, Peru.

Am J Trop Med Hyg 2021 May 3. Epub 2021 May 3.

1Division of Infectious Disease, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas.

Fasciola hepatica is highly prevalent in the highlands of Peru. School-age children have the greatest risk of infection. Mass treatment of at-risk populations has been proposed to control the infection and prevent complications. Read More

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Vaccination with cathepsin L phage-exposed mimotopes, single or in combination, reduce size, fluke burden, egg production and viability in sheep experimentally infected with Fasciola hepatica.

Parasitol Int 2021 Aug 16;83:102355. Epub 2021 Apr 16.

Unidad Académica de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Guerrero, Ciudad Altamirano, Guerrero, Mexico.

Fascioliasis is a worldwide emergent zoonotic disease that significantly constrains the productivity of livestock. In this study, fluke burdens, liver fluke size and biomass, faecal eggs counts, serum levels of hepatic enzymes and immune response were assessed in sheep vaccinated with peptide mimotopes of cathepsin L and infected with metacercariae. A total of 25 sheep were allocated randomly into five groups of five animals each, and experimental groups were immunised with 1 × 10 filamentous phage particles of cathepsin L1 (CL1) (TPWKDKQ), CL2 (YGSCFLR) and mixtures of CL1 + CL2 mimotopes, in combination with Quil A adjuvant, and wild-type M13KE phage in a two-vaccination scheme on weeks 0 and 4. Read More

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Human fascioliasis presenting as liver abscess: clinical characteristics and management.

Hepatol Int 2021 Jun 17;15(3):804-811. Epub 2021 Apr 17.

Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.

Background: Human fascioliasis, caused by the liver flukes F. hepatica, and F. gigantica, is a neglected tropical disease that causes health problems in many regions of the world. Read More

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