650,206 results match your criteria factors survival

Preoperative Nutritional Scores as Host-Related Prognostic Factors for Both Overall Survival and Postoperative Complications in Stage II - III Colorectal Cancer Patients.

Dis Colon Rectum 2021 Apr 26. Epub 2021 Apr 26.

Department of Colorectal Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 1040045, Japan.

Background: In the tumor-node-metastasis eighth edition, nutritional status and inflammatory scores are newly described as host-related prognostic factors for esophageal cancer, hepatocellular carcinoma, and pancreatic cancer. However, only age and race are listed as host-related prognostic factors for colorectal cancer.

Objective: To evaluate the prognostic significance of nutritional and inflammatory scores for postoperative outcomes in colorectal cancer patients. Read More

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Liver transplantation for patients with acute-on-chronic liver failure (ACLF) in Europe: results of the ELITA/EF-CLIF collaborative study (ECLIS).

J Hepatol 2021 Apr 24. Epub 2021 Apr 24.

Department of hepatogastroenterology, Hepatology and Liver Transplantation Unit, HCL Hopital de la Croix-Rousse, Lyon, France.

Background And Aims: Liver transplantation (LT) has been proposed to be an effective salvage therapy even for the sickest patients with acute-on-chronic liver failure (ACLF). This large collaborative study was designed to address the current clinical practice and outcomes of ACLF patients wait listed (WL) for LT in Europe.

Methods: Retrospective study including 308 consecutive ACLF patients, listed in 20 centres across 8 European countries, from January 2018 to June 2019. Read More

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Aortic neck IFU violations during EVAR for ruptured infrarenal aortic aneurysms are associated with increased in-hospital mortality.

Ann Vasc Surg 2021 May 2. Epub 2021 May 2.

Division of Vascular Surgery and Endovascular Therapy, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Objective: Vascular surgeons treating patients with ruptured abdominal aortic aneurysm (rAAA) must make rapid treatment decisions and sometimes lack immediate access to endovascular devices meeting the anatomic specifications of the patient at hand. We hypothesized that endovascular treatment of rAAA (rEVAR) outside manufacturer instructions-for-use (IFU) guidelines would have similar in-hospital mortality compared to patients treated on-IFU or with an infrarenal clamp during open repair (rOAR).

Methods: Vascular Quality Initiative (VQI) datasets for endovascular and open aortic repair were queried for patients presenting with ruptured infrarenal AAA between 2013-2018. Read More

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Mortality and Healthcare Utilization of Patients with Compensated Hypercapnia.

Ann Am Thorac Soc 2021 May 5. Epub 2021 May 5.

University of Michigan, 1259, Ann Arbor, Michigan, United States.

Rationale: Acute hypercapnic respiratory failure has been shown to be associated with worse outcomes for various disease states, but less is known about patients with compensated hypercapnic respiratory failure. Although these patients have a normal pH, it remains unknown whether chronically elevated partial pressures of carbon dioxide (PaCO2), irrespective of etiology, put patients at risk of adverse events.

Objectives: To understand the burden of and clinical factors associated with morbidity and mortality in patients with compensated hypercapnic respiratory failure. Read More

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Serum phosphate is associated with mortality among patients admitted to ICU for acute pancreatitis.

United European Gastroenterol J 2021 May 5. Epub 2021 May 5.

Service de Réanimation Médicale, CHRU Jean Minjoz, Besançon, France.

Background And Aims: Routine laboratory tests can be useful predictors in the early assessment of the severity and mortality of acute pancreatitis (AP). The aim of this study was to evaluate the accuracy of clinical and laboratory parameters for the prediction of mortality among patients admitted to the intensive care unit (ICU) for AP.

Methods: We conducted a retrospective analysis of prospectively collected data from Beth Israel Deaconess Hospital made publicly available to examine the relationship between routine clinical and laboratory parameters with respect to mortality for AP. Read More

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Factors associated with psychological distress for couples facing head and neck cancer: A systematic literature review.

Psychooncology 2021 Apr 9. Epub 2021 Apr 9.

King's Mill Hospital, Nottinghamshire Healthcare NHS Foundation Trust, Sutton-in-Ashfield, UK.

Objectives: Cancer patients in supportive relationships display improved health and survival outcomes. Identifying factors that might respond to intervention for Head and Neck Cancer (HNC) dyads is important as HNC patients and their partners experience heightened distress. This article systematically reviewed and evaluated the research findings and methodological quality of studies which identified factors influencing psychological distress for couples facing HNC. Read More

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Relationship between blood neutrophil-lymphocyte ratio and renal tubular atrophy/interstitial fibrosis in IgA nephropathy patients.

J Clin Lab Anal 2021 May 5:e23774. Epub 2021 May 5.

Department of Nephrology, Ningbo Hwamei Hospital, University of Chinese Academy of Sciences, Ningbo, China.

Background: The study aimed to explore the relationship between neutrophil-lymphocyte ratio(NLR) in peripheral blood and renal tubular atrophy/interstitial fibrosis and to evaluate the clinical significance of NLR in IgA nephropathy (IgAN) patients.

Methods: A Total of 263 IgAN patients were included. The participants were categorized into four groups based on quartile of NLR. Read More

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Serum potassium levels and prognosis in HBV-associated decompensated cirrhosis.

J Clin Lab Anal 2021 May 5:e23775. Epub 2021 May 5.

Department of Clinical Laboratory, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, China.

Background: Serum potassium disorders are commonly seen in patients with advanced cirrhosis and have a detrimental effect on clinical outcome, but its role in HBV-related decompensated cirrhosis (DeCi) is remained to be illustrated. We aim to assess the effects of serum potassium on outcomes in HBV-DeCi patients.

Methods: Retrospective study included 155 subjects. Read More

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Response to Letter to Editor regarding article, 'Association between dental factors and mortality'.

Int Endod J 2021 Jun;54(6):1001

Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.

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Letter to Editor regarding article, 'Association between dental factors and mortality'.

T Wu G Wang X Pan

Int Endod J 2021 Jun;54(6):1002

Department of Dental Implantology and Prosthodontics, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.

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Prevalence of atrial fibrillation and outcomes in older long-term care residents: a systematic review.

Age Ageing 2021 May;50(3):744-757

Department of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.

Background: anticoagulation is integral to stroke prevention for atrial fibrillation (AF), but there is evidence of under-treatment in older people in long-term care (LTC).

Objective: to synthesise evidence on the prevalence and outcomes (stroke, mortality or bleeding) of AF in LTC and the factors associated with the prescription of anticoagulation.

Methods: studies were identified from Medline, CINAHL, PsycINFO, Scopus and Web of Science from inception to 31 October 2019. Read More

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Predictive Factors of Chemotherapy Initiation after Biliary Drainage for Advanced Biliary Tract Cancer: A Retrospective Multicenter Study.

J Gastrointestin Liver Dis 2021 May 3. Epub 2021 May 3.

IMAD, Department of Gastroenterology and Digestive Oncology, University Hospital, Nantes, France.

Background And Aims: In unresectable biliary tract cancers, the management of biliary obstruction is often the first step before introduction of chemotherapy. Our aim was to study the predictive factors of chemotherapy initiation after biliary drainage in a series of patients presenting with advanced biliary tract cancer and obstructive jaundice.

Methods: Data of all patients treated for unresectable biliary tract cancer with initial biliary obstruction requiring a drainage in six institutions, from January 2009 to January 2019, were retrospectively collected. Read More

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Breast cancer survival and its prognostic factors in the United Arab Emirates: A retrospective study.

PLoS One 2021 5;16(5):e0251118. Epub 2021 May 5.

Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.

Background: Data on breast cancer survival and its prognostic factors are lacking in the United Arab Emirates (UAE). Sociodemographic and pathologic factors have been studied widely in western populations but are very limited in this region. This study is the first to report breast cancer survival and investigate prognostic factors associated with its survival in the UAE. Read More

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A nomogram prediction of overall survival based on lymph node ratio, AJCC 8th staging system, and other factors for primary pancreatic cancer.

PLoS One 2021 5;16(5):e0249911. Epub 2021 May 5.

Department of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Background: As a malignant tumor with poor prognosis, accurate and effective prediction of the prognosis of pancreatic cancer (PC) is crucial.

Methods: A total of 12,909 patients diagnosed with pancreatic cancer were selected from the Surveillance, Epidemiology, and End Results program between 2004 and 2016. The sex, age, ethnicity, marital status, metastasis status, radiotherapy, chemotherapy, tumor size, regional nodes examined, regional nodes positive of each patient were recorded. Read More

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Clinical significance of central systolic blood pressure in LV diastolic dysfunction and CV mortality.

PLoS One 2021 5;16(5):e0250653. Epub 2021 May 5.

Division of Cardiology, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea.

Background And Aims: Cardiovascular (CV) disease is the major cause of death in patients with end-stage kidney disease (ESKD). Left ventricular (LV) diastolic dysfunction reflects LV pressure overload and is common in patients with ESKD. Recently, there have been studies on the usefulness of central blood pressure (BP); however, the relationship between central BP and LV diastolic dysfunction is not clear in dialysis patients with preserved systolic function. Read More

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Treatment strategies and predicting lymph node metastasis in elderly patients with papillary thyroid microcarcinoma.

Medicine (Baltimore) 2021 May;100(18):e25811

Department of Surgical Oncology, Shaanxi Provincial People's Hospital.

Abstract: This study aims to explore the prognostic variables for elderly papillary thyroid microcarcinoma (PTMC) patients as well as create a nomogram that could predict the occurrence of cervical lymph node metastasis (CLNM) on the basis of a large population database with high quality.A total of 5165 PTMC patients from Surveillance, Epidemiology, and End Results database database were enrolled in the study. In the meantime, we retrospectively collected 205 PTMC patients who underwent thyroidectomy in our medical center as an external control to test the accuracy of the model. Read More

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Platelet count patterns and patient outcomes in sepsis at a tertiary care center: Beyond the APACHE score.

Medicine (Baltimore) 2021 May;100(18):e25013

Department of Critical Care, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Abstract: Acute physiology and chronic health evaluation II (APACHE-II) scoring system is used to classify disease severity of patients in the intensive care unit. However, several limitations render the scoring system inadequate in identifying risk factors associated with outcomes. Little is known about the association of platelet count patterns, and the timing of platelet count and other hematologic parameters in predicting mortality in patients with sepsis. Read More

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Toll-like receptor 5 and 8 in hepatocellular carcinoma.

APMIS 2021 May 5. Epub 2021 May 5.

Surgery Research Unit, Medical Research Center Oulu, Cancer and Translational Medicine Research Unit, University of Oulu, Oulu University Hospital, Oulu, Finland.

Background: Toll-like receptors (TLRs) are components of innate immunity, but also have a role in carcinogenesis. The prognostic value of TLR5 and TLR8 tumor expression was examined in contrast with known risk markers Ki67 and p53.

Methods: All HCC patients from Oulu University Hospital with available representative tumor sample were included in this study (n=182). Read More

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The Impact of Socioeconomic Status on Stage at Presentation, Receipt of Diagnostic Imaging, Receipt of Treatment, and Overall Survival in Colorectal Cancer Patients.

Int J Cancer 2021 May 5. Epub 2021 May 5.

Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Socioeconomic factors influence patterns of care in colorectal cancer. This study investigates the impact of socioeconomic status (SES) on stage at presentation, receipt of diagnostic imaging, receipt of treatment, and overall survival (OS) in a universal healthcare system. The Ontario Cancer Registry (OCR) was accessed to identify a cohort of patients diagnosed with colorectal adenocarcinoma from 2007-2016 in Ontario, Canada. Read More

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Breast cancer disparities in outcomes; unmasking biological determinants associated with racial and genetic diversity.

Clin Exp Metastasis 2021 May 5. Epub 2021 May 5.

Department of Surgery, Weill Cornell Medical College, 420 E 70th Street, New York City, NY, 10065, USA.

Breast cancer (BC) remains a leading cause of death among women today, and mortality among African American women in the US remains 40% higher than that of their White counterparts, despite reporting a similar incidence of disease over recent years. Previous meta-analyses and studies of BC mortality highlight that tumor characteristics, rather than socio-economic factors, drive excess mortality among African American women with BC. This is further complicated by the heterogeneity of BC, where BC can more appropriately be defined as a collection of diseases rather than a single disease. Read More

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First report of a leopard (Panthera pardus)-bonobo (Pan paniscus) encounter at the LuiKotale study site, Democratic Republic of the Congo.

Primates 2021 May 5. Epub 2021 May 5.

LuiKotale Bonobo Project, Centre for Research and Conservation, Royal Zoological Society of Antwerp, Antwerp, Belgium.

Predation is a major cause of mortality in non-human primates, and considered a selective force in the evolution of primate societies. Although larger body size is considered as protection against predation, evidence for predation on great apes by carnivores comes from chimpanzees (Pan troglodytes), gorillas (Gorilla gorilla), and orangutans (Pongo spp.). Read More

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From Survival to Glamour: Motivations for Engaging in Transactional Sex and Relationships Among Adolescent Girls and Young Women in South Africa.

AIDS Behav 2021 May 5. Epub 2021 May 5.

Health Systems Research Unit, South African Medical Research Council, Francie van Zijl Drive, Parow Valley, Tygerberg, Cape Town, South Africa.

We explored transactional sex and relationships (TSR) among South African adolescent girls and young women (AGYW) using (1) survey data from 4,399 AGYW aged 15-24 years, and (2) qualitative data from 237 AGYW and 38 male peers. Ten percent of sexually active AGYW reported having ever had transactional sex; 14% reported having stayed in a relationship for money or material items. Factors associated with higher reporting of TSR included HIV positivity, higher food insecurity, and alcohol use. Read More

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Factors Associated with Infant Feeding Choices Among Women with HIV in Botswana.

Matern Child Health J 2021 May 5. Epub 2021 May 5.

Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.

Introduction: In resource-constrained settings, infant feeding decisions among women with HIV (WHIV) must balance the risk of infant HIV acquisition from breastfeeding with increased mortality associated with formula feeding. WHO guidelines recommend countries principally promote a single feeding method for WHIV, either breastfeeding or formula feeding. In 2016, Botswana revised its policy of formula feeding for infants born to WHIV, instead promoting exclusive breastfeeding during the first 6 months of life. Read More

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[CAR T-cell therapy for children and adolescents with acute lymphatic leukemia].

Internist (Berl) 2021 May 5. Epub 2021 May 5.

Klinik für Kinder- und Jugendmedizin, Schwerpunkt Stammzelltransplantation und Immunologie, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Deutschland.

Background: Acute lymphatic leukemia is the most common malignant disease in children. Despite a good prognosis, new therapeutic concepts are needed for patients with refractory and relapsed disease.

Question: The importance of chimeric antigen receptor (CAR) T‑cell therapy for patients with refractory and post-stem cell transplantation. Read More

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Echocardiography Predictors of Survival in Hypertensive Patients With Left Ventricular Hypertrophy.

Am J Hypertens 2021 May 5. Epub 2021 May 5.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

Background: Left ventricular hypertrophy (LVH) is a well-known target organ damage. Concentric hypertrophy is the strongest predictor of increased risk of cardiovascular events, but the predictive value of individual echocardiographic parameters remains unclear.The aim of this study was to search for echocardiographic and hemodynamic variables associated with concentric and eccentric remodeling and their association with long-term cardiovascular outcomes. Read More

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Risk factors for critical illness and death among adult Brazilians with COVID-19.

Rev Soc Bras Med Trop 2021 28;54:e0014 2021. Epub 2021 Apr 28.

Universidade Federal de Lavras, Departamento de Nutrição, Programa de Pós-Graduação em Nutrição e Saúde, Lavras, MG, Brasil.

Introduction: Severe acute respiratory syndrome coronavirus 2 has infected more than 9,834,513 Brazilians up to February 2021. Knowledge of risk factors of coronavirus disease among Brazilians remains scarce, especially in the adult population. This study verified the risk factors for intensive care unit admission and mortality for coronavirus disease among 20-59-year-old Brazilians. Read More

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Determinants of usage and non-adherence to noninvasive ventilation in children and adults with Duchenne muscular dystrophy.

J Clin Sleep Med 2021 May 4. Epub 2021 May 4.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Diego, San Diego, CA.

Study Objectives: Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that leads to chronic respiratory insufficiency and failure. Use of home noninvasive ventilation (NIV) has been linked to improved outcomes including reduced mortality. Despite the importance of NIV, factors promoting optimal NIV usage and determinants of non-adherence have not been rigorously examined. Read More

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In patients with heart failure, enhanced ventilatory response to exercise is associated with severe obstructive sleep apnea.

J Clin Sleep Med 2021 May 5. Epub 2021 May 5.

Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil.

Study Objectives: Patients with chronic heart failure (CHF) while undergoing exercise test, frequently exhibit elevated ratio of minute ventilation over CO₂ output (VE/VCO₂ slope). One of the factors contributing to this elevated slope is increased chemosensitivity to CO₂, as this slope significantly correlates with the slope of the ventilatory response to CO₂ rebreathing at rest. A previous study in patients with CHF and central sleep apnea (CSA) has shown the highest VE/VCO2 slope during exercise was associated with the most severe CSA. Read More

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Association of sarcopenia with mortality and end-stage renal disease in those with chronic kidney disease: a UK Biobank study.

J Cachexia Sarcopenia Muscle 2021 May 5. Epub 2021 May 5.

Leicester Kidney Lifestyle Team, Department of Health Sciences, University of Leicester, Leicester, UK.

Background: Sarcopenia, a degenerative and generalized skeletal muscle disorder involving the loss of muscle function and mass, is an under-recognized problem in clinical practice, particularly in chronic kidney disease (CKD). We aimed to investigate the prevalence of sarcopenia in individuals with CKD, its risk factors, and its association with all-cause mortality and progression to end-stage renal disease (ESRD).

Methods: UK Biobank participants were grouped according to the presence of CKD (defined as an estimated glomerular filtration rate <60 mL/min/1. Read More

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Concurrent chemoradiotherapy versus radiotherapy alone for patients with locally advanced esophageal squamous cell carcinoma in the era of intensity modulated radiotherapy: a propensity score-matched analysis.

Thorac Cancer 2021 May 5. Epub 2021 May 5.

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: To investigate the survival benefit of concurrent chemoradiotherapy (CCRT) for patients with locally advanced esophageal squamous cell carcinoma (ESCC) during the years of intensity-modulated radiotherapy (IMRT).

Methods: Medical records of 1089 patients with ESCC who received IMRT from January 2005 to December 2017 were retrospectively reviewed. A total of 617 patients received CCRT, 472 patients received radiotherapy (RT) alone. Read More

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