Heart Rhythm 2021 Apr 6. Epub 2021 Apr 6.
Cardio-Thoracic Unit, Bordeaux University Hospital (CHU), Pessac-Bordeaux, France; IHU Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, Pessac-Bordeaux, France.
Background: Possible mechanisms of left-axis deviation (LAD) in the setting of left bundle branch block (LBBB) include differences in cardiac electrophysiology, structure, or anatomic axis.
Objective: The purpose of this study was to clarify the mechanism(s) responsible for LAD in patients with LBBB.
Methods: Twenty-nine patients with nonischemic cardiomyopathies and LBBB underwent noninvasive electrocardiographic imaging (ECGi), cardiac computed tomography, and magnetic resonance imaging in order to define ventricular electrical activation, characterize cardiac structure, and determine the cardiac anatomic axis. Read More