439 results match your criteria facilitating responding


Older People's Experiences of Living with, Responding to and Managing Sensory Loss.

Healthcare (Basel) 2021 Mar 15;9(3). Epub 2021 Mar 15.

School of Nursing, University of Notre Dame Australia, Darlinghurst, NSW 2010, Australia.

(1) Background: Ageing is associated with a decline in sensory function (sight, hearing, taste, touch and smell), which play an important role in the maintenance of an older person's health, independence and well-being. (2) Methods: This qualitative study obtained data through face-to-face semi-structured interviews with a convenience sample of thirteen community-dwelling adults 65 years and older. Themes were derived inductively, guided by semi-structured interviews. Read More

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Galactosyldiacylglycerols: From a Photosynthesis-Associated Apparatus to Structure-Defined Assembling.

J Agric Food Chem 2021 Apr 1. Epub 2021 Apr 1.

Department of Engineering, Faculty of Technical Science, Aarhus University, Gustav Wieds Vej 10, 8000 Aarhus, Denmark.

Being ubiquitously present in plants, microalgae, and cyanobacteria and as the major constituents of thylakoid membranes, monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) make up approximately 52 and 26%, respectively, of chloroplast lipids. Thylakoid membranes harbor the photosynthetic complexes and numerous essential biochemical pathways where MGDG and DGDG play a central role in facilitating photosynthesis light reaction, maintaining chloroplast morphology, and responding to abiotic stresses. Furthermore, these galactolipids are also bioactive compounds with antitumor, antimicrobial, antiviral, immunosuppressive, and anti-inflammatory activities and important nutritional value. Read More

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Responding to family violence: Variations in knowledge, confidence and skills across clinical professions in a large tertiary public hospital.

SAGE Open Med 2021 10;9:20503121211000923. Epub 2021 Mar 10.

Allied Health, The Royal Melbourne Hospital, Melbourne, VIC, Australia.

Introduction: Healthcare workers play a vital role in assessing and appropriately responding to family violence. Discipline-specific differences in the readiness to respond have been indicated in the literature but no studies have directly compared multiple disciplines using the same measure. Given the imperative need for a hospital-wide, multidisciplinary approach to managing family violence, this study aimed to compare and contrast clinician perceived levels of knowledge, confidence and clinical readiness to manage disclosures of family violence across major professional groups in a tier 1, tertiary adult trauma hospital in Australia. Read More

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Perceptions, experiences, and preferences for partner services among Black and Latino men who have sex with men and transwomen in North Carolina.

Ethn Health 2021 Mar 18:1-15. Epub 2021 Mar 18.

Institute for Global Health & Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Objectives: In the United States, sexually transmitted infections (STIs) disproportionately affect men who have sex with men (MSM) and transwomen of color. Partner services can prevent STI transmission by facilitating testing and treatment for partners of individuals diagnosed with an STI. Understanding client perspectives towards partner services is critical to their acceptance and uptake. Read More

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Facilitating young children's numeracy talk in play: The role of parent prompts.

J Exp Child Psychol 2021 Jul 14;207:105124. Epub 2021 Mar 14.

Department of Psychology, University of Chicago, Chicago, IL 60637, USA.

Previous research has demonstrated the contribution of parents' number language to children's own engagement with numbers and later mathematical achievement. Although there is evidence that both the quantity and complexity of parent number talk contribute to children's math learning, it is unclear whether different forms of parents' number talk-statements versus prompts-offer unique contributions to how children engage in math. We examined parent number talk among 50 dyads of parents and 2- to 4-year-olds during pretend play, coding parents' provisions of informative number statements and prompts inviting children to engage in number talk. Read More

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Community nurses' experiences of the Swedish Dignity Care Intervention for older persons with palliative care needs - A qualitative feasibility study in municipal home health care.

Int J Older People Nurs 2021 Mar 13:e12372. Epub 2021 Mar 13.

Faculty of Medicine and Health, School of Health Sciences, Örebro University, Örebro, Sweden.

Objectives: The Swedish Dignity Care Intervention (DCI-SWE) is an intervention for people with palliative care needs to enhance their dignity. The original DCI was developed in Scotland, where it was tested by nurses in municipal care. In this study, the DCI has been tested for the first time in a Swedish home health care context. Read More

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Distinct neuron phenotypes may serve object feature sensing in the electrosensory lobe of .

J Exp Biol 2021 Mar 11. Epub 2021 Mar 11.

Departamento Neurociencias Integrativas y Computacionales, Instituto de Investigaciones Biológicas Clemente Estable, Av. Italia 3318, Montevideo, Uruguay

Early sensory relays circuits in the vertebrate medulla often adopt a cerebellum-like organization specialized for comparing primary afferent inputs with central expectations. These circuits usually have a dual output, carried by center ON and center OFF neurons responding in opposite ways to the same stimulus at the center of their receptive fields. Here we show in the electrosensory lateral line lobe of Gymnotiform weakly electric fish that basilar pyramidal neurons, representing 'ON' cells, and non-basilar pyramidal neurons, representing 'OFF' cells, have different intrinsic electrophysiological properties. Read More

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Under-standing: How embodied states shape inference-making.

Acta Psychol (Amst) 2021 Apr 6;215:103276. Epub 2021 Mar 6.

University of Michigan, Department of Psychology, 350 Church St., Ann Arbor, MI 48109-1043, USA. Electronic address:

How do embodied states influence the inferences people make about the meaning that is intended by communicators? We propose that embodied states encourage mental representation of certain meanings while inhibiting others, thereby facilitating or hindering comprehension in social interactions and potentially causing miscommunication. Four experiments demonstrate that bodily postures incompatible with the intended meaning of a sentence attenuated inferences of those meanings, especially when the intended meaning was not articulated directly and required more extensive inference-making effort. Participants were faster at responding to sentences containing verbs inferring a sitting position when they were sitting than when they were standing, and vice versa. Read More

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Using a High Quantum Yield Fluorescent Probe with Two-Photon Excitation to Detect Cisplatin in Biological Systems.

ACS Sens 2021 03 3;6(3):1400-1406. Epub 2021 Mar 3.

Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai 200241, China.

A direct detection protocol for the anticancer drug of cisplatin is highly desirable for studying its actions and side effects. In this work, a high quantum yield fluorescent probe with two-photon excitation to detect cisplatin was designed. The probe (RD640-TC) was based on the rhodamine 640 (Rh640) fluorophore, responding to cisplatin with red fluorescence. Read More

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Centers for Disease Control and Prevention National Center for Environmental Health/Agency for Toxic Substances and Disease Registry Roles in Hurricane Response and Postdisaster Mosquito Control1.

J Am Mosq Control Assoc 2020 Jun;36(2s):78-81

Emergency Management, Radiation, and Chemical Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341.

Hurricanes and other natural disasters leave behind multifaceted and complex environmental challenges that may contribute to adverse health outcomes, such as increased potential for exposure to vector-borne disease. Through an incident management system tailored for the Centers for Disease Control and Prevention (CDC), the National Center for Environmental Health/Agency for Toxic Substances and Disease Registry (NCEH/ATSDR) fulfills a leadership role in facilitating the agency's natural disaster emergency response activities through coordination with other CDC programs, liaising with other government agencies and impacted jurisdictions, and responding to requests for technical assistance. On the ground, NCEH/ATSDR deploys environmental health (EH) practitioners who provide consultation and inform mosquito control efforts from a systematic perspective. Read More

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Facilitating Sustainable Disaster Risk Reduction in Indigenous Communities: Reviving Indigenous Worldviews, Knowledge, and Practices through Two-Way Partnering.

Int J Environ Res Public Health 2021 Jan 20;18(3). Epub 2021 Jan 20.

Yalu Marŋgithinyaraw, Galiwin'ku, East Arnhem Land, The Northern Territory 0822, Australia.

The Sendai Framework of Action 2015-2030 calls for holistic Indigenous disaster risk reduction (DRR) research. Responding to this call, we synergized a holistic philosophical framework (comprising ecological systems theory, symbolic interactionism, and intersectionality) and social constructionist grounded theory and ethnography within a critical Indigenous research paradigm as a methodology for exploring how diverse individual and contextual factors influence DRR in a remote Indigenous community called Galiwinku, in the Northern Territory of Australia. Working together, Indigenous and non-Indigenous researchers collected stories in local languages using conversations and yarning circles with 20 community members, as well as participant observations. Read More

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January 2021

When Will He Talk? An Evidence-Based Tutorial for Measuring Progress Toward Use of Spoken Words in Preverbal Children With Autism Spectrum Disorder.

Am J Speech Lang Pathol 2021 01 21;30(1):1-18. Epub 2021 Jan 21.

Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.

Purpose Professionals face substantial challenges determining whether and when children with autism spectrum disorder (ASD) who are not yet using spoken words will use spoken language as their primary means of communication. This tutorial provides speech-language pathologists with practical guidance on how to measure expressive language predictors for progress monitoring and making intervention decisions for children with ASD who are preverbal. Method This tutorial is a repackaging effort that seeks to make the research accessible to clinicians wishing to implement evidence-based practice. Read More

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January 2021

Regional cooperation is essential to combatting health emergencies in the Global South.

Global Health 2021 01 9;17(1). Epub 2021 Jan 9.

United Nations University Institute on Comparative Regional Integration Studies (UNU-CRIS), Potterierei 72, 8000, Brugge, Belgium.

Since COVID-19 was first discovered, it exploded into a pandemic resulting in devastating effects on human lives and a global recession. While there have been discussions that COVID-19 will accelerate the 'end of globalization and multilateralism', we have already seen the high costs of non-cooperation in responding to the virus resulting in sub-optimal use of resources, rapid spread of the virus between countries, and, ultimately, significant loss of life. In spite of their favorable demographic structures and relatively young populations, countries in the Global South are still harshly affected in both epidemiological and economic terms. Read More

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January 2021

LncRNA XIST/miR-137 axis strengthens chemo-resistance and glycolysis of colorectal cancer cells by hindering transformation from PKM2 to PKM1.

Cancer Biomark 2021 ;30(4):395-406

Department of Gastroenterology, the First Affiliated Hospital of Bengbu Medical College, Anhui, China.

Background: Glycolysis was an essential driver of chemo-resistance in colorectal cancer (CRC), albeit with limited molecular explanations.

Objective: We strived to elucidate the involvement of lncRNA XIST/miR-137/PKM axis in chemo-tolerance and glycolysis of CRC.

Methods: Altogether 212 pairs of tumor tissues and adjacent normal tissues were collected from CRC patients. Read More

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January 2021

A pragmatic factorial randomized controlled trial of transdiagnostic internet-delivered cognitive behavioural therapy: Exploring benefits of homework reflection questionnaires and twice-weekly therapist support.

Internet Interv 2020 Dec 1;22:100357. Epub 2020 Dec 1.

MindSpot Clinic, eCentreClinic, Department of Psychology, Macquarie University, Australian Hearing Hub Building, Sydney, NSW 2109, Australia.

With the growing demand for internet-delivered cognitive behavioural therapy (iCBT), this pragmatic factorial (2 × 2 × 2) randomized controlled trial evaluated strategies for facilitating iCBT engagement and outcomes in routine care. Specifically, the benefits to patients and therapists of using homework reflection questionnaires and offering patients twice-weekly therapist support were examined. Patients ( = 632) accepted into iCBT for depression and/or anxiety were randomly assigned to complete homework reflection questionnaires or not (factor 1), receive once- or twice-weekly support (factor 2), and to receive care from therapists employed in one of two settings (iCBT clinic or a community mental health clinic; factor 3). Read More

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December 2020

A case series of advanced renal cell carcinoma patients treated with neoadjuvant cabozantinib prior to cytoreductive nephrectomy within the phase 2 CABOPRE trial.

Oncotarget 2020 Nov 24;11(47):4457-4462. Epub 2020 Nov 24.

Medical Oncology Department, Hospital Universitario 12 de Octubre, Comunidad de Madrid, Madrid, Spain.

Cytoreductive nephrectomy has long been used to improve disease control in metastastic Renal Cell Carcinoma (mRCC). However, based on the results of the CARMENA and SURTIME trials, cytoreductive nephrectomy is no longer the standard of care in patients requiring upfront systemic treatment and it should be avoided in most poor-risk patients. Nevertheless, it should still be considered in patients responding to systemic therapy and good-risk patients not requiring systemic treatment. Read More

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November 2020

The role of emergency preparedness exercises in the response to a mass casualty terrorist incident: A mixed methods study.

Int J Disaster Risk Reduct 2020 Jun;46:101503

Behavioural Science, Emergency Response Department Science & Technology, Public Health England, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK.

Simulation exercises are an important part of emergency preparedness activities for the healthcare community but evidence of their impact on the response to real major incidents is limited. This project studied the impact of health emergency preparedness exercises (HEPEs) on the response to a mass casualty terrorist incident. The mixed methods study design was adopted comprising an on-line survey and follow up individual interviews. Read More

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State-Transition Modeling of Human-Robot Interaction for Easy Crowdsourced Robot Control.

Sensors (Basel) 2020 Nov 15;20(22). Epub 2020 Nov 15.

Department of Adaptive Machine Systems, Osaka University, Suita 565-0871, Japan.

Robotic salespeople are often ignored by people due to their weak social presence, and thus have difficulty facilitating sales autonomously. However, for robots that are remotely controlled by humans, there is a need for experienced and trained operators. In this paper, we suggest crowdsourcing to allow general users on the internet to operate a robot remotely and facilitate customers' purchasing activities while flexibly responding to various situations through a user interface. Read More

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November 2020

Tumor-Targeted Nanomedicine for Immunotherapy.

Acc Chem Res 2020 12 8;53(12):2765-2776. Epub 2020 Nov 8.

Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.

Therapeutic manipulation of the immune system against cancer has revolutionized the treatment of several advanced-stage tumors. While many have benefited from these treatments, the proportion of patients responding to immunotherapies is still low. Nanomedicines have promise to revolutionize tumor treatments through spatiotemporal control of drug activity. Read More

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December 2020

Person-Centered Communication Between Health Care Professionals and COVID-19-Infected Older Adults in Acute Care Settings: Findings From Wuhan, China.

J Gerontol B Psychol Sci Soc Sci 2021 03;76(4):e225-e229

Second Military Medical University, School of Nursing, Shanghai, China.

Objectives: The current study aims to explore person-centered communication between health care professionals and COVID-19-infected older patients in acute care settings.

Methods: The current qualitative study explored the communication between professionals and COVID-19-infected older adults in the acute care setting through 2 rounds of interviews with physicians and nurses who provided direct care and treatment for COVID-19-infected older patients in Wuhan, China. We explored the possibilities and significance of facilitating effective communication despite multiple challenges in the pandemic. Read More

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Breast Cancer Cells Induce a Pro-inflammatory Response to Mitigate Immune Mediation in a 3D Culture Model.

Anticancer Res 2020 Nov;40(11):6179-6193

Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Growth factors and cytokines mediate complex interactions between cells within the breast tumour microenvironment. In advanced cancer, an excess of regulatory T (T) lymphocytes and lack of natural killer (NK) cells in tumour-infiltrating lymphocyte populations may reflect a shift to pro-tumorigenic adaptive immune mechanisms. To facilitate targeted assessment of the interactions between tumour and immune cells ex vivo, three-dimensional (3D) culture systems are able to better recapitulate the in vivo microenvironment, recreating the anatomy of tumours. Read More

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November 2020

Increase in internetwork functional connectivity in the human brain with attention capture.

J Neurophysiol 2020 12 14;124(6):1885-1899. Epub 2020 Oct 14.

Department of Psychology, Vanderbilt University, Nashville, Tennessee.

Attention is often extolled for its selective neural properties. Yet, when powerfully captured by a salient unexpected event, attention can give rise to a broad cascade of systemic effects for evaluating and adaptively responding to the event. Using graph theory analysis combined with fMRI, we show here that the extensive psychophysiological and cognitive changes associated with such attention capture are related to large-scale distributed changes in the brain's functional connectivity. Read More

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December 2020

Human-Animal Interaction and the Emergence of SARS-CoV-2.

JMIR Public Health Surveill 2020 10 7;6(4):e22117. Epub 2020 Oct 7.

Department of Medical Microbiology and Immunology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.

The COVID-19 pandemic has affected all sectors of society, from health and economics to socialization and travel. The level and extent of this impact are unprecedented. Although the cause of COVID-19 was quickly identified to be a new coronavirus (SARS-CoV-2), the world was poorly prepared for preventing its spread. Read More

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October 2020

Children and young people's experiences of completing mental health and wellbeing measures for research: learning from two school-based pilot projects.

Child Adolesc Psychiatry Ment Health 2020 16;14:35. Epub 2020 Sep 16.

Evidence Based Practice Unit (EBPU), University College London and the Anna Freud National Centre for Children and Families, London, UK.

Background: In recent years there has been growing interest in child and adolescent mental health and wellbeing, alongside increasing emphasis on schools as a crucial site for research and intervention. This has coincided with an increased use of self-report mental health and wellbeing measures in research with this population, including in school-based research projects. We set out to explore the way that children and young people perceive and experience completing mental health and wellbeing measures, with a specific focus on completion in a school context, in order to inform future measure and research design. Read More

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September 2020

Microtia and craniofacial microsomia: Content analysis of facebook groups.

Int J Pediatr Otorhinolaryngol 2020 Nov 9;138:110301. Epub 2020 Aug 9.

Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, 4650 Sunset Blvd, MS#96, Los Angeles, CA, 90027, USA. Electronic address:

Objective: An increasing number of patients use social media for health-related information and social support. This study's objective was to describe the content posted on Facebook groups for individuals with microtia and/or craniofacial microsomia (CFM) and their families in order for providers to gain insight into patient and family needs and experiences to inform clinical care.

Methods: Two months of posts, images, comments, and "like" responses from two Facebook groups in the US and the UK were recorded and analyzed using content analysis. Read More

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November 2020

COVID-19 & an NGO and university developed interactive portal: a perspective from Iran.

Health Technol (Berl) 2020 Aug 17:1-6. Epub 2020 Aug 17.

Student Research Committee, School of Management & Medical informatics, Tabriz University of Medical Sciences, Tabriz, Iran.

On 19 February 2020, Iran reported the initial cases of novel coronavirus (2019-nCoV). As of 21 March 2020, Iran had reported 175,927 COVID-19 cases, including 8425 deaths. One of the best approaches for responding to COVID-19 is rapid detection, early isolation, and quick treatment of the disease. Read More

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Development of the Signposting Questionnaire for Autism (SQ-A): measurement comparison with the 10-item Autism Spectrum Quotient-Child and the Strengths and Difficulties Questionnaire in the UK and Latvia.

Mol Autism 2020 08 15;11(1):64. Epub 2020 Aug 15.

School of Psychology, Cardiff University, Cardiff, UK.

Background: Recognising the signs of autism spectrum disorder (ASD) can be a challenge for frontline professionals. The use of brief parent-completed questionnaires for recording the signs of ASD in school-aged children may be an important and efficient contributor to professional insight. However, to date, such questionnaires have not been designed to be used in coordination with current standardised Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnostic tools. Read More

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Selected omissions and capstone presentations: a new approach to student-centered integrative physiology education.

Adv Physiol Educ 2020 Sep;44(3):448-452

Center for Health Sciences, Oklahoma State University, Tulsa, Oklahoma.

Here, we describe a pedagogical approach that combines didactics with active learning to facilitate integration across physiological systems in a team-taught, graduate-level physiology course. We covered the major physiological systems, with each system preceded by an overview of its evolution/ontogeny to provide a broader perspective. Lectures provided a framework for integration by giving examples of how each system interacted with systems that preceded and followed. Read More

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September 2020

Advances in allergen immunotherapy for asthma.

Curr Opin Allergy Clin Immunol 2020 12;20(6):602-608

Transylvania University, Faculty of Medicine.

Purpose Of Review: Allergen immunotherapy (AIT) is a well-known disease-modifying intervention for allergic diseases. Its benefit in allergic asthma, ranging from prevention to facilitating asthma control, is yet to be clarified.

Recent Findings: In 2017, following several well-designed randomised controlled trials (RCTs) with house-dust mites (HDM) sublingual (SLIT) tablets in asthma, global initiative for asthma (GINA) guidelines highlighted the need to treat the allergic component of asthma. Read More

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December 2020

Pakistan's Health System Against COVID-19: Where Do Things Stand?

J Coll Physicians Surg Pak 2020 Jun;30(6):3-8

Independent Researcher, State of New York, USA.

The national response of Pakistan's health system to COVID-19 was assessed by applying a framework of three distinct tiers. The first tier assessed politico-economic ecosystems: lockdown procedures, contact-screening, monetary/organisational arrangements for economically deprived groups, and travel restrictions. The second tier assessed intervention measures according to six building blocks of WHO: strategic vision highlighted by National Action Plan COVID-19, inadequacy and urban bias of healthcare professionals, expanded bed capacity, enhanced laboratory diagnostic capacity and financial assistance. Read More

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