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The Critical Role of Health Information Technology in the Safe Integration of Behavioral Health and Primary Care to Improve Patient Care.

J Behav Health Serv Res 2021 Oct 19. Epub 2021 Oct 19.

Foothold Technology, New York, NY, USA.

Integrated behavioral health and primary care is a set of related approaches to enhance care delivery, safety, and quality through closer collaboration and coordination among clinicians and care organizations in these two fields. Technology (e.g. Read More

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October 2021

A learning health systems approach to integrating electronic patient-reported outcomes across the health care organization.

Learn Health Syst 2021 Oct 1;5(4):e10263. Epub 2021 Mar 1.

Surgical Outcomes Research Center, Department of Surgery University of Washington Seattle Washington USA.

Introduction: Foundational to a learning health system (LHS) is the presence of a data infrastructure that can support continuous learning and improve patient outcomes. To advance their capacity to drive patient-centered care, health systems are increasingly looking to expand the electronic capture of patient data, such as electronic patient-reported outcome (ePRO) measures. Yet ePROs bring unique considerations around workflow, measurement, and technology that health systems may not be poised to navigate. Read More

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October 2021

Do research participants share genomic screening results with family members?

J Genet Couns 2021 Oct 19. Epub 2021 Oct 19.

Division of Genetics and Genomics and the Manton Center for Orphan Diseases Research, Boston Children's Hospital, Boston, MA, USA.

The public health impact of genomic screening can be enhanced by cascade testing. However, cascade testing depends on communication of results to family members. While the barriers and facilitators of family communication have been researched following clinical genetic testing, the factors impacting the dissemination of genomic screening results are unknown. Read More

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October 2021

Informed Consent for Secondary Research under the New NIH Data Sharing Policy.

Authors:
Mark A Rothstein

J Law Med Ethics 2021 ;49(3):489-494

The new NIH data sharing policy, effective January 2023, requires researchers to submit a data management and data sharing plan in their grant application. Expanded data sharing, encouraged by NIH to facilitate secondary research, will require informed consent documents to explain data sharing plans, limitations, and procedures. Read More

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January 2021

Barriers and facilitators to accessing health and social care services for people living in homeless hostels: a qualitative study of the experiences of hostel staff and residents in UK hostels.

BMJ Open 2021 Oct 18;11(10):e053185. Epub 2021 Oct 18.

Pathway Charity, London, UK.

Introduction: The number of people living in homeless hostels in the UK has steadily increased over the past decade. Despite people experiencing homelessness often having considerable health problems and a range of complex needs frequently in association with addictions, the experiences of hostel staff and residents especially in relation to accessing health and social care support have seldom been explored. The aim of this paper is to identify the barriers and facilitators to accessing health and social care services for people living in homeless hostels. Read More

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October 2021

Effect of Communication and Education within the Rehabilitation Team: Therapists' and Nurses' Views.

Ann Geriatr Med Res 2021 Oct 19. Epub 2021 Oct 19.

Department of Rehabilitation, Seoul National University Bundang Hospital, Korea.

Objective: To improve the rehabilitation team's awareness of patient mobility and participation by improving communication between therapists and nurses and conducting patient education.

Design: This study used a non-equivalent control group with a nonsynchronized design. To facilitate communication between therapists and nurses, we used a manual for mobility management to improve the sharing of information on the functional status of patients. Read More

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October 2021

Radiotherapy biobanking: current landscape, opportunities, challenges, and future aspirations.

J Pathol Clin Res 2021 Oct 17. Epub 2021 Oct 17.

Newcastle Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

Half of all cancer patients receive radiotherapy, which makes a substantial contribution to their long-term disease control/cure. There are significant inter-patient differences in response, both in terms of efficacy and toxicity (frequently delayed onset) which are difficult to predict. With the introduction of technological improvements (e. Read More

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October 2021

Assessment of minority language skills in English-Irish-speaking bilingual children: A survey of SLT perspectives and current practices.

Int J Lang Commun Disord 2021 Oct 18. Epub 2021 Oct 18.

School of Health Science, Ulster University, Newtownabbey, Northern Ireland.

Background: An increasing number of children in the UK and Ireland are growing up speaking more than one language. The many advantages of bilingualism are acknowledged; however, this increased linguistic diversity presents particular challenges for speech and language therapists (SLTs). The case is often more complex with speakers of minority languages such as Welsh and Irish, which are acquired almost exclusively in bilingual contexts. Read More

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October 2021

Study protocol: Traditional Chinese Medicine (TCM) syndrome differentiation for heart failure patients and its implication for long-term therapeutic outcomes of the Qiliqiangxin capsules.

Chin Med 2021 Oct 16;16(1):103. Epub 2021 Oct 16.

School of Chinese Medicine, University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong, People's Republic of China.

Background: Syndrome differentiation is a commonly used methodology and practice in Traditional Chinese Medicine (TCM) guiding the diagnosis and treatment of diseases including heart failure (HF). However, previous clinical trials seldom consider the impact of syndrome patterns on the outcome evaluation of TCM formulae. Qiliqiangxin (QLQX) capsule is a TCM formula with cardiotonic effect to improve the cardiovascular function for heart failure with proven efficacy from well-designed clinical trials. Read More

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October 2021

SMART v1.0: A Database for Small Molecules with Functional Implications in Plants.

Interdiscip Sci 2021 Oct 14. Epub 2021 Oct 14.

State Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China.

We developed SMART v1.0 ( http://smart.omicstudio. Read More

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October 2021

Building Capacity of Community Health Centers to Overcome Data Challenges with the Development of an Agile COVID-19 Public Health Registry: A Multi-State Quality Improvement Effort.

J Am Med Inform Assoc 2021 Oct 14. Epub 2021 Oct 14.

National Association of Community Health Centers, Bethesda, MD USA.

Objective: During the COVID-19 pandemic, federally qualified health centers rapidly mobilized to provide SARS-CoV-2 testing, COVID-19 care, and vaccination to populations at increased risk for COVID-19 morbidity and mortality. We describe the development of a reusable public health data analytics system for reuse of clinical data to evaluate the health burden, disparities, and impact of COVID-19 on populations served by health centers.

Materials And Methods: The Multi-State Data Strategy engaged project partners to assess public health readiness and COVID-19 data challenges. Read More

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October 2021

Unobserved Observers: Nurses' Perspectives About Sharing Feedback on the Performance of Resident Physicians.

Acad Med 2021 Oct 12. Epub 2021 Oct 12.

C. Bhat is a resident physician, Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada; ORCID: https://orcid.org/0000-0003-3198-6450. K.A. LaDonna is assistant professor, Department of Innovation in Medical Education, University of Ottawa, Ottawa, Ontario, Canada. S. Dewhirst is a lecturer, Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada; ORCID: https://orcid.org/0000-0003-1996-6692. S. Halman is assistant professor, Department of Medicine, University of Ottawa and the Ottawa Hospital, Ottawa, Ontario, Canada; ORCID: http://orcid.org/0000-0002-5474-9696. K. Scowcroft is a research assistant, Department of Innovation in Medical Education, University of Ottawa, Ottawa, Ontario, Canada. S. Bhat is a registered nurse, Department of Emergency Medicine, the Ottawa Hospital, Ottawa, Ontario, Canada. W.J. Cheung is associate professor, Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada; ORCID: https://orcid.org/0000-0002-2730-8190.

Purpose: Postgraduate training programs are incorporating feedback from registered nurses (RNs) to facilitate holistic assessments of resident performance. RNs are a potentially rich source of feedback because they often observe trainees during clinical encounters when physician supervisors are not present. However, RN perspectives about sharing feedback have not been deeply explored. Read More

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October 2021

Medical Education Transformation: Lifestyle Medicine in Undergraduate and Graduate Medical Education, Fellowship, and Continuing Medical Education.

Am J Lifestyle Med 2021 Sep-Oct;15(5):514-525. Epub 2021 Apr 29.

University of South Carolina Greenville, South Carolina.

A gaping void of adequate lifestyle medicine (LM) training exists across the medical education continuum. The American College of Lifestyle Medicine's (ACLM's) undergraduate medical education (UME) Task Force champions the need for widespread integration of LM curriculum in UME by sharing ideas for catalyzing success, lessons learned, and publishing standards and competencies to facilitate curriculum reform. When it comes to graduate medical education and fellowship, the ACLM and American Board of Lifestyle Medicine have made great strides in filling the void, developing both Educational and Experiential Pathways through which physicians may become certified LM Physicians or LM Specialists (LMSs). Read More

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Teleclinical Microbiology.

Am J Clin Pathol 2021 Oct 13. Epub 2021 Oct 13.

Department of Molecular Biology and Umeå Centre for Microbial Research, Umeå University, Umeå, Sweden.

Objectives: Telemedicine can compensate for the lack of health care specialists in response to protracted humanitarian crises. We sought to assess the usability of a teleclinical microbiology (TCM) program to provide diagnostic services in a hard-to-reach region of Syria.

Methods: A semimobile station was equipped with conventional micrograph and macrograph digital imaging systems. Read More

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October 2021

Why Do Citizens Share COVID-19 Fact-Checks Posted by Chinese Government Social Media Accounts? The Elaboration Likelihood Model.

Int J Environ Res Public Health 2021 09 24;18(19). Epub 2021 Sep 24.

College of Public Administration, Huazhong University of Science and Technology, Wuhan 430074, China.

Widespread misinformation about COVID-19 poses a significant threat to citizens long-term health and the combating of the disease. To fight the spread of misinformation, Chinese governments have used official social media accounts to participate in fact-checking activities. This study aims to investigate why citizens share fact-checks about COVID-19 and how to promote this activity. Read More

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September 2021

Constructing Japanese MeSH term dictionaries related to the COVID-19 literature.

Genomics Inform 2021 Sep 30;19(3):e25. Epub 2021 Sep 30.

Computer Science Department, The University of Sheffield, Western Bank, Sheffield S10 2TN, UK.

The coronavirus disease 2019 (COVID-19) pandemic has led to a flood of research papers and the information has been updated with considerable frequency. For society to derive benefits from this research, it is necessary to promote sharing up-to-date knowledge from these papers. However, because most research papers are written in English, it is difficult for people who are not familiar with English medical terms to obtain knowledge from them. Read More

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September 2021

Design and implementation of an international, multi-arm, multi-stage platform master protocol for trials of novel SARS-CoV-2 antiviral agents: Therapeutics for Inpatients with COVID-19 (TICO/ACTIV-3).

Clin Trials 2021 Oct 10:17407745211049829. Epub 2021 Oct 10.

CHIP Centre of Excellence for Health, Immunity, and Infections, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.

Background/aims: Safe and effective therapies for COVID-19 are urgently needed. In order to meet this need, the Accelerating COVID-19 Therapeutic Interventions and Vaccines public-private partnership initiated the Therapeutics for Inpatients with COVID-19. Therapeutics for Inpatients with COVID-19 is a multi-arm, multi-stage platform master protocol, which facilitates the rapid evaluation of the safety and efficacy of novel candidate antiviral therapeutic agents for adults hospitalized with COVID-19. Read More

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October 2021

COVID-19 and the ageing workforce: global perspectives on needs and solutions across 15 countries.

Int J Equity Health 2021 10 7;20(1):221. Epub 2021 Oct 7.

Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, #10-00 Tahir Foundation Building, Singapore, 117549, Singapore.

Background: COVID-19 has a direct impact on the employment of older people. This adds to the challenge of ageism. The World Health Organization has started a worldwide campaign to combat ageism and has called for more research and evidence-based strategies that have the potential to be scaled up. Read More

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October 2021

The Angelman Syndrome Online Registry - A multilingual approach to support global research.

Eur J Med Genet 2021 Oct 4;64(12):104349. Epub 2021 Oct 4.

Institute of Human Genetics, University of Leipzig Medical Center, Leipzig, Germany; Center for Rare Diseases, University of Leipzig Medical Center, Leipzig, Germany. Electronic address:

In collaboration with the German Angelman syndrome (AS) community, we developed a web-based AS Online Registry to congregate existing as well as future information and scientifically quantify observations made by parents, families and medical professionals. With its user-friendly design as well as its concise and multilingual questionnaire, the registry aims at families who had so far refrained from being recruited by other, more comprehensive and/or English-only, registries. Data can be entered by both parents/families and medical professionals. Read More

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October 2021

Patients' with chronic kidney disease and their relatives' perspectives on advance care planning: A meta-ethnography.

J Ren Care 2021 Oct 7. Epub 2021 Oct 7.

Department of Nephrology, Odense University Hospital, Odense, Denmark.

Introduction: Advance care planning is a process that supports adults of any age and stage of illness in understanding and sharing their values, life goals, and preferences regarding medical care. Chronic kidney disease is a progressive and lifelong disease. Close relatives often represent patients' most important support. Read More

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October 2021

Androgen deprivation therapy and excess mortality in men with prostate cancer during the initial phase of the COVID-19 pandemic.

PLoS One 2021 7;16(10):e0255966. Epub 2021 Oct 7.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Background: Men have a higher risk of death from COVID-19 than women and androgens facilitate entrance of the SARS-CoV-2 virus into respiratory epithelial cells. Thus, androgen deprivation therapy may reduce infection rates and improve outcomes for COVID-19. In the spring of 2020, Sweden was highly affected by COVID-19. Read More

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October 2021

Generativity among persons providing or receiving peer or mutual support: A scoping review.

Psychiatr Rehabil J 2021 Oct 7. Epub 2021 Oct 7.

Department of Psychiatry.

Objective: People with lived experience of mental illness or distress can help others recover through peer or mutual support. One way they may help others recover is by fostering generativity, which refers to one's concern for and contributions toward the betterment of others, including future generations (e.g. Read More

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October 2021

Spatial organization of transcribing loci during early genome activation in Drosophila.

Curr Biol 2021 Sep 29. Epub 2021 Sep 29.

Department of Biology, New York University, New York, NY 10003, USA. Electronic address:

The early Drosophila embryo provides unique experimental advantages for addressing fundamental questions of gene regulation at multiple levels of organization, from individual gene loci to the entire genome. Using 1.5-h-old Drosophila embryos undergoing the first wave of genome activation, we detected ∼110 discrete "speckles" of RNA polymerase II (RNA Pol II) per nucleus, two of which were larger and localized to the histone locus bodies (HLBs). Read More

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September 2021

Protecting the healthcare workforce during COVID-19: a qualitative needs assessment of employee occupational health in the US national Veterans Health Administration.

BMJ Open 2021 10 4;11(10):e049134. Epub 2021 Oct 4.

Center for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, California, USA

Objective: Early in the COVID-19 pandemic, US Veterans Health Administration (VHA) employee occupational health (EOH) providers were tasked with assuming a central role in coordinating employee COVID-19 screening and clearance for duty, representing entirely novel EOH responsibilities. In a rapid qualitative needs assessment, we aimed to identify learnings from the field to support the vastly expanding role of EOH providers in a national healthcare system.

Methods: We employed rapid qualitative analysis of key informant interviews in a maximal variation sample on the parameters of job type, rural versus urban and provider gender. Read More

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October 2021

A scalable software solution for anonymizing high-dimensional biomedical data.

Gigascience 2021 Oct;10(10)

Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Medical Informatics, Charitéplatz 1, 10117 Berlin, Germany.

Background: Data anonymization is an important building block for ensuring privacy and fosters the reuse of data. However, transforming the data in a way that preserves the privacy of subjects while maintaining a high degree of data quality is challenging and particularly difficult when processing complex datasets that contain a high number of attributes. In this article we present how we extended the open source software ARX to improve its support for high-dimensional, biomedical datasets. Read More

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October 2021

AANA21: Reflections on the Combined AOSSM-AANA 2021 Annual Meeting.

Arthroscopy 2021 Oct;37(10):3001-3002

Assistant Editor-in-Chief.

At the American Orthopaedic Society for Sports Medicine (AOSSM)-Arthroscopy Association of North America (AANA) 2021 Annual Meeting in Nashville, Tennessee, collaboration was the word of the day. AAOSM and AANA are a great pair, and many of us are long-time members of both associations. The attendance was unprecedented. Read More

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October 2021

A State-of-the Art Review of SNOMED CT Terminology Binding and Recommendations for Practice and Research.

Methods Inf Med 2021 Sep 28. Epub 2021 Sep 28.

eHealth and Structured Information Unit, National Board of Health and Welfare, Stockholm, Sweden.

Background:  Unambiguous sharing of data requires information models and terminology in combination, but there is a lack of knowledge as to how they should be combined, leading to impaired interoperability.

Objectives:  To facilitate creation of guidelines for SNOMED CT terminology binding we have performed a literature review to find existing recommendations and expose knowledge gaps. The primary audience is practitioners and researchers working with terminology binding. Read More

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September 2021

Physiology labs during a pandemic: What did we learn?

Adv Physiol Educ 2021 Dec;45(4):803-809

Department of Science and Mathematics, Biology, Clarke University, Dubuque, Iowa.

This article captures a collective reflection on the successes and challenges we experienced when teaching physiology laboratories online during the COVID-19 pandemic. Physiology instructors from six institutions discussed their own efforts to redesign meaningful physiology laboratories that could be taught remotely, as the nation scrambled to respond to the sudden shift out of the classroom. Despite the complexity of this task, clear themes emerged as our courses transitioned to an online format in spring 2020 and were solidified in the fall of 2020. Read More

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December 2021

How to Start Up a National Wildlife Health Surveillance Programme.

Animals (Basel) 2021 Aug 30;11(9). Epub 2021 Aug 30.

Department of Viroscience, Erasmus University Medical Centre, 3015 GD Rotterdam, The Netherlands.

Whilst multiple countries in Europe have wildlife health surveillance (WHS) programmes, they vary in scope. In many countries, coordinated general surveillance at a national scale is not conducted and the knowledge of wildlife health status in Europe remains limited. Learning lessons from countries with established systems may help others to effectively implement WHS schemes. Read More

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Using Death Cafés as a method for discussing death and dying with third year student nurses.

Int J Palliat Nurs 2021 Sep;27(7):352-360

Independent, Death café facilitator.

Background: Death Cafés are increasingly being held to facilitate discussions around death and dying and end-of-life issues with the public. They are thought to provide a safe, confidential and interactive space in which sensitive and supportive conversations about death and dying and end-of-life are shared.

Aim: To explore nursing students' experiences of participating in a modified Death Café and its impact on their learning about death and dying. Read More

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September 2021