292,044 results match your criteria extracts


Georgian Med News 2021 Mar(312):150-156

Tbilisi State Medical University, Institute of Pharmacochemistry I. Kutateladze, Georgia.

The purpose of the study was to develop cosmetic products using the natural resources of Georgia As components, the therapeutic mud of Akhtala, bentonite clay, perlite, liver oil of the sea cartilaginous fish katran, habitat of coastal waters were used. From the Black Sea, oils and extracts from plants in large numbers growing in Georgia. When studying the physicochemical characteristics of the products obtained and their compliance with standards, tests according to GOST 31460-2012 were used. Read More

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Polycyclic aromatic hydrocarbons in airborne particulate matter samples from Hanoi, Vietnam: Particle size distribution, aryl hydrocarbon ligand receptor activity, and implication for cancer risk assessment.

Chemosphere 2021 Apr 30;280:130720. Epub 2021 Apr 30.

Centre for Environmental Technology and Sustainable Development (CETASD), University of Science, Vietnam National University, Hanoi, 334 Nguyen Trai, Hanoi, 11400, Viet Nam. Electronic address:

Concentrations and profiles of unsubstituted and methylated polycyclic aromatic hydrocarbons (PAHs and Me-PAHs) were analyzed in airborne particulate matter (PM) samples collected from high-traffic roads in Hanoi urban area. Levels of PAHs and Me-PAHs ranged from 210 to 660 (average 420) ng/m in total PM, and these pollutants were mainly associated with fine particles (PM) rather than coarser ones (PM and PM). Proportions of high-molecular-weight compounds (i. Read More

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Optimization and application of QuEChERS and SPE methods followed by LC-PDA for the determination of triazines residues in fruits and vegetables from Pietermaritzburg local supermarkets.

Food Chem 2021 Apr 20;360:129818. Epub 2021 Apr 20.

Department of Chemistry, University of KwaZulu-Natal, Private Bag X01, Scottsville, Pietermaritzburg 3209, South Africa. Electronic address:

QuEChERS and solid phase extraction (SPE) methods were optimized and applied for the extraction of triazines in fruit and vegetables. These extraction methods are easy, effective, rugged and safe. Also, they have the ability to purify the extracts which leads to lower detection limits and higher recoveries of the analytes. Read More

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A multi-analytical strategy for evaluation of quality and authenticity of artichoke food supplements for overweight control.

J Chromatogr A 2021 Mar 28;1647:462102. Epub 2021 Mar 28.

Instituto de Química Orgánica General (CSIC). Juan de la Cierva, 3 28006 Madrid Spain. Electronic address:

Despite the widespread use of artichoke-based food supplements for obesity control (FSOC), studies on evaluation of the quality/authenticity of these commercial products are scarce. To that aim, a new multi-analytical strategy, based on the use of gas chromatography coupled to mass spectrometry (GC-MS) and high performance liquid chromatography coupled to ultraviolet and mass spectrometry detection (HPLC-UV-MS), in combination with chemometrics, has been developed. Twenty-one artichoke FSOC and different bract and leaf extracts (used as reference samples) were analysed. Read More

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Bacillus circulans MTCC 7906 aided facile development of bioconjugate nano-silica alkaline protease formulation with superlative dehairing potential.

Environ Pollut 2021 Apr 27;285:117181. Epub 2021 Apr 27.

Department of Veterinary Pathology, College of Veterinary Science, Guru Angad Dev Veterinary & Animal Sciences University, Ludhiana, 141 004, Punjab, India.

The tannery industries utilize environmentally hazardous chemicals to achieve dehairing of animal hides, which causes enormous waterbed pollution & high TDS load. Alkaline protease enzyme for dehairing can be an effective solution to resolve the environmental problems of the tannery industry waste. However, stable, cost-efficient and eco-benign formulations of alkaline protease need to be developed for commercial applications in the tannery industry. Read More

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The anti-cancer properties of neem () through its antioxidant activity in the liver; its pharmaceutics and toxic dosage forms; a literature review.

J Complement Integr Med 2021 May 10. Epub 2021 May 10.

Department of Physiology and Medical Physics, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Objectives: The neem () have been used in herbal medicine for the treatment of multiple diseases, particularly cancer. The mechanism of anti-cancer properties of neem are far from clear. However, it is well accepted that anti-cancer effects of neem is mediated via its hepatic anti-oxidant activity. Read More

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Metabolomic fingerprinting of Brazilian marine sponges: a case study of Plakinidae species from Fernando de Noronha Archipelago.

Anal Bioanal Chem 2021 May 8. Epub 2021 May 8.

Laboratório de Produtos Naturais (LAPROMAR), Instituto de Química, Universidade Federal Fluminense, Niterói, RJ, 24020-005, Brazil.

Marine sponges from the Plakinidae family are well known for hosting cytotoxic secondary metabolites and the Brazilian Atlantic coast and its oceanic islands have been considered as a hotspot for the discovery of new Plakinidae species. Herein, we report the chemical profile among cytotoxic extracts obtained from four species of Plakinidae, collected in Fernando de Noronha Archipelago (PE, Northeastern Brazil). Crude organic extracts of Plakinastrella microspiculifera, Plakortis angulospiculatus, Plakortis insularis, and Plakortis petrupaulensis showed strong antiproliferative effects against two different cancer cell lines (HCT-116: 86. Read More

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Untargeted metabotyping to study phenylpropanoid diversity in crop plants.

Physiol Plant 2021 May 7. Epub 2021 May 7.

Leibniz Institute for Plant Genetics and Crop Plant Research, Gatersleben, Germany.

Plant genebanks constitute a key resource for breeding to ensure crop yield under changing environmental conditions. Because of their roles in a range of stress responses, phenylpropanoids are promising targets. Phenylpropanoids comprise a wide array of metabolites; however, studies regarding their diversity and the underlying genes are still limited for cereals. Read More

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Chemical profiling, in vitro antioxidant, membrane stabilizing and antimicrobial properties of wild growing Murraya paniculata from Amarkantak (M.P.).

Sci Rep 2021 May 7;11(1):9691. Epub 2021 May 7.

Department of Biotechnology, Indira Gandhi National Tribal University, Amarkantak, Anuppur, Madhya Pradesh, 484887, India.

The excessive usage of antibiotics in humans and veterinary medicine has lead to the emergence of antibiotic resistance and now requires the use of novel antibiotics. There has been increased interest towards plants as source of drugs because of their pharmacological potency and long traditional usage. The aim of the current study was to evaluate bioactive components, antioxidant, and anti-inflammatory activities of the leaf extracts of Murraya paniculata, a plant traditionally used in Indian medicinal system. Read More

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from fungus gardens of fungus-growing ants produce antifungals that inhibit the specialized parasite .

Appl Environ Microbiol 2021 May 7. Epub 2021 May 7.

Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA

Within animal associated microbiomes, the functional roles of specific microbial taxa are often uncharacterized. Here, we use the fungus-growing ant system, a model for microbial symbiosis, to determine the potential defensive roles of key bacterial taxa present in the ants' fungus gardens. Fungus gardens serve as an external digestive system for the ants, with mutualistic fungi in the genus spp. Read More

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Ameliorating activity of polyphenolic-rich extracts of L. leaves on pancreatic β-cell dysfunction in streptozotocin-induced diabetic rats.

J Complement Integr Med 2021 May 7. Epub 2021 May 7.

Department of Biochemistry, Phytomedicine, Natural Products, Drug and Biochemical Toxicology Group, Landmark University, Omu Aran, PMB 1001, Kwara State, Nigeria.

Objectives: To assess the ameliorative activity of polyphenolic-rich extracts of leaves on β-cell dysfunction in type-II diabetes (T2DM).

Methods: Total phenolic and flavonoid contents; α-amylase and α-glucosidase inhibitory actions and qualitative analysis of the bioactive compounds of the polyphenolic-rich extract of leaves were investigated using gas chromatography-mass spectroscopy (GC-MS). Diabetes mellitus (DM) was induced by single intraperitoneal injection of streptozotocin (60 mg/kg body weight) and the rats were orally given bound phenolic (BPE) and free phenolic extracts (FPE) of (B. Read More

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Site environment type - The main factor of urban road dust toxicity?

Ecotoxicol Environ Saf 2021 May 4;218:112290. Epub 2021 May 4.

Institute of Safety Engineering, The Main School of Fire Service, 52/54 Słowackiego St., 01-629 Warsaw, Poland.

The main objective of the study was to determine the effects of the water extracts of urban road dust (URD) samples on the growth inhibition and mortality rate of Heterocypris incongruens in various site environment type. We collected 24 samples of the road dust close to highways, main roads, crossroads as well as at other places i.e. Read More

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Analysis of boswellic acids in dietary supplements containing Indian frankincense (Boswellia serrata) by Supercritical Fluid Chromatography.

J Pharm Biomed Anal 2021 Apr 27;201:114106. Epub 2021 Apr 27.

Institute of Pharmacy, Pharmacognosy, Center for Molecular Biosciences (CMBI), University of Innsbruck, Innsbruck, Austria. Electronic address:

Boswellic acids, a class of triterpenes, are the bioactive constituents in Indian frankincense, an herbal drug with pronounced anti-inflammatory activity. In this study their separation and quantification in B. serrata extracts is reported for the first time by using Supercritical Fluid Chromatography. Read More

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A novel non-destructive technique for qualitative and quantitative measurement of dental erosion in its entirety by porosity and bulk tissue-loss.

J Dent 2021 May 4:103688. Epub 2021 May 4.

School of Life Science, Pharmacy and Chemistry, Kingston University London, United Kingdom.

Objective: To explore the potential of combining non-contact profilometry(NCP) and confocal laser scanning microscopy(CLSM) data to measure the entire erosive process non-destructively and to validate findings using inductively coupled plasma-atomic emission spectroscopy(ICP-AES), scanning electron microscopy(SEM) and surface microhardness(SMH) using the same samples throughout.

Methods: Polished bovine enamel samples(n = 35) were divided into groups(7/group) with similar SMH values. Samples underwent individual erosive challenges(1% citric acid,pH3. Read More

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Finite-size transitions in complex membranes.

Biophys J 2021 May 4. Epub 2021 May 4.

Van 't Hoff Institute for Molecular Sciences and Informatics Institute, University of Amsterdam, Amsterdam 1098 XH, The Netherlands; Max Planck Institute for Polymer Research, Ackermannweg 10, Mainz 55128, Germany.

The lipid-raft hypothesis postulates that cell membranes possess some degree of lateral organization. The hypothesis has attracted much attention while remaining controversial, with an underlying mechanism that remains elusive. One idea that supports rafts relies on the membrane to lie near a critical point. Read More

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In vitro studies of Annona muricata L. extract-loaded electrospun scaffolds for localized treatment of breast cancer.

J Biomed Mater Res B Appl Biomater 2021 May 7. Epub 2021 May 7.

Department of Mechanical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts, USA.

This paper presents in vitro studies of the sustained release of Annona muricata leaf extracts (AME) from hybrid electrospun fibers for breast cancer treatment. Electrospun hybrid scaffolds were fabricated from crude AME extracts, poly(lactic-co-glycolic acid)/gelatin (PLGA/Ge) and pluronic F127. The physicochemical properties of the AME extract and scaffolds were studied. Read More

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Synergistic and Antagonistic Effects of Biogenic Silver Nanoparticles in Combination With Antibiotics Against Some Pathogenic Microbes.

Front Bioeng Biotechnol 2021 20;9:652362. Epub 2021 Apr 20.

Department of Biology, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.

The latest advances in green nanoparticle synthesis have preserved natural and non-renewable resources and decreased environmental pollution. The current study was designed to evaluate silver nanoparticles (AgNPs) fabricated using aqueous extracts of two medicinal plants, L. (Kaff Maryam) and . Read More

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Extraction, Purification, Bioactivities and Application of Matrix Proteins From Pearl Powder and Nacre Powder: A Review.

Front Bioeng Biotechnol 2021 20;9:649665. Epub 2021 Apr 20.

College of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China.

Natural pearls are formed when sand or parasites (irritants) accidentally enter into the oyster body and form pearls under the cover of the nacre layer. Pearl powder is a powdery substance by grinding pearls into small grains, however, the nacre powder is the inner layer of outer corner layer and middle prism layer. Pearl medicine in China has a history of more than 2,000 years, pearl has the effects of calming the mind, clearing the eyes, detoxifying the muscle and so on. Read More

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Natural products targeting the synthesis of β(1,3)-D-glucan and chitin of the fungal cell wall. Existing drugs and recent findings.

Phytomedicine 2021 Mar 27:153556. Epub 2021 Mar 27.

Instituto de Biología Funcional y Genómica and Departamento de Microbiología y Genética, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca, Salamanca, Spain. Electronic address:

Background: During the last three decades systemic fungal infections associated to immunosuppressive therapies have become a serious healthcare problem. Clinical development of new antifungals is an urgent requirement. Since fungal but not mammalian cells are encased in a carbohydrate-containing cell wall, which is required for the growth and viability of fungi, the inhibition of cell wall synthesizing machinery, such as β(1,3)-D-glucan synthases (GS) and chitin synthases (CS) that catalyze the synthesis of β(1-3)-D-glucan and chitin, respectively, represent an ideal mode of action of antifungal agents. Read More

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Osteogenic effects of exosomes derived from human chorion membrane extracts.

Biomater Res 2021 May 6;25(1):16. Epub 2021 May 6.

Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Guro Hospital, 80 Guro-dong, Guro-gu, Seoul, 08308, Republic of Korea.

Objective: Human chorion membrane extracts (CME) are known to exhibit osteogenic effects when used for treating human osteoblast-like cells (MG63 cells), but the active compound in CME remains unknown. The aim of this study was to identify the presence of exosomes in CME and to determine the osteogenic effect of CME exosomes on MG63 cells.

Methods: Exosomes were isolated from human placenta CME using the ExoQuick-TC solution and were characterized. Read More

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Antibacterial and antioxidant activities of extracts and isolated compounds from the roots extract of Cucumis prophetarum and in silico study on DNA gyrase and human peroxiredoxin 5.

BMC Chem 2021 May 6;15(1):32. Epub 2021 May 6.

Department of Applied Chemistry, School of Applied Natural Science, Adama Science and Technology University, P.O.Box 1888, Adama, Ethiopia.

Background: Cucumis prophetarum is traditionally used to treat liver and lung disorders, heart failure, diarrhea, gonorrhea, skin infections, intestinal problems and cancer. In the present work, the isolation of two novel compounds along with their antibacterial and antioxidant activities is reported for the first time.

Methods: Silica gel column chromatography was applied to separate constituents of the roots of C. Read More

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A Proposal Towards a Rational Classification of the Antimicrobial Activity of Acetone Tree Leaf Extracts in a Search for New Antimicrobials.

Planta Med 2021 May 6. Epub 2021 May 6.

Phytomedicine Programme, Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa.

Many scientists investigate the potential of finding new antibiotics from plants, leading to more than a thousand publications per year. Many different minimum inhibitory concentrations of extracts have been proposed to decide if an extract has interesting activity that could lead to the discovery of a new antibiotic. To date, no rational explanation has been given for the selection criteria different authors have used. Read More

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13C NMR Dereplication Using MixONat Software: A Practical Guide to Decipher Natural Products Mixtures.

Planta Med 2021 May 6. Epub 2021 May 6.

Univ Angers, SONAS, SFR QUASAV, Faculty of Health Sciences, Dpt Pharmacy, Angers, France.

The growing use of herbal medicines worldwide requires ensuring their quality, safety, and efficiency to consumers and patients. Quality controls of vegetal extracts are usually undertaken according to pharmacopeial monographs. Analyses may range from simple chemical experiments to more sophisticated but more accurate methods. Read More

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qNMR quantification of phenolic compounds in dry extract of Myrcia multiflora leaves and its antioxidant, anti-AGE, and enzymatic inhibition activities.

J Pharm Biomed Anal 2021 Apr 28;201:114109. Epub 2021 Apr 28.

Núcleo de Estudos Químicos de Micromoléculas da Amazônia - NEQUIMA, Instituto de Ciências Exatas, Universidade Federal do Amazonas, Manaus, Amazonas, Brazil. Electronic address:

Myrcia multiflora (Lam.) DC. is often used in Brazilian folk medicine to control diabetes. Read More

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The effect of extractive lacto-fermentation on the bioactivity and natural products content of Pittosporum angustifolium (gumbi gumbi) extracts.

J Chromatogr A 2021 Apr 20;1647:462153. Epub 2021 Apr 20.

Department of Pharmaceutical and Toxicological Chemistry named after Arzamastsev of the Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow 119991, Russia; School of Pharmacy and Biomedical Sciences, La Trobe Institute for Molecular Sciences, La Trobe University, Edwards Rd, Bendigo 3550, Australia.

Pittosporum angustifolium, known as gumbi gumbi, is a native Australian plant, which has traditionally been used as an Aboriginal medicine. This study investigates the effect of different solvents and extractive fermentation on the content and natural products composition of Pittosporum angustifolium extracts, and compares their antioxidant activity, in vitro α-amylase inhibition, and anti-inflammatory properties. Anti-inflammatory activity of the extracts was determined by measuring the inhibition of nitric oxide (NO) production. Read More

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Fabrication and characterization of basil essential oil microcapsule-enriched mayonnaise and its antimicrobial properties against Escherichia coli and Salmonella Typhimurium.

Food Chem 2021 Apr 23;359:129940. Epub 2021 Apr 23.

Ankara University, Faculty of Engineering, Department of Food Engineering, 06830 Gölbaşı/Ankara, Turkey.

Nowadays, as consumers tend to avoid foods containing synthetic preservatives, technologically processed plant extracts can be a good alternative to these preservatives. In this study, previously obtained basil essential oil microcapsules (BEOM) were added to mayonnaise in order to produce a microbiologically safe product with improved physicochemical properties. Mayonnaises were prepared with 0%, 0. Read More

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Disjoint subspaces for common and distinct component analysis: Application to the fusion of multi-task FMRI data.

J Neurosci Methods 2021 May 3;358:109214. Epub 2021 May 3.

Department of Computer Science and Electrical Engineering, University of Maryland Baltimore County, Baltimore, 21250 MD, USA.

Background: Data-driven methods such as independent component analysis (ICA) makes very few assumptions on the data and the relationships of multiple datasets, and hence, are attractive for the fusion of medical imaging data. Two important extensions of ICA for multiset fusion are the joint ICA (jICA) and the multiset canonical correlation analysis and joint ICA (MCCA-jICA) techniques. Both approaches assume identical mixing matrices, emphasizing components that are common across the multiple datasets. Read More

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In-Depth Structural Characterization and Quantification of Cerebrosides and Glycosphingosines with Gas-Phase Ion Chemistry.

Anal Chem 2021 May 6. Epub 2021 May 6.

Department of Chemistry Purdue University 560 Oval Drive West Lafayette, Indiana 47907, United States.

Cerebrosides (n-HexCer) and glycosphingosines (n-HexSph) constitute two sphingolipid subclasses. Both are comprised of a monosaccharide headgroup (glucose or galactose in mammalian cells) linked via either an α- or β-glycosidic linkage to the sphingoid backbone (n = α or β, depending upon the nature of the linkage to the anomeric carbon of the sugar). Cerebrosides have an additional amide-bonded fatty acyl chain linked to the sphingoid backbone. Read More

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