156,009 results match your criteria extraction methods

Word synonym relationships for text analysis: A graph-based approach.

Hend Alrasheed

PLoS One 2021 27;16(7):e0255127. Epub 2021 Jul 27.

Department of Information Technology, College of Computer and Information Sciences, King Saud University, Riyadh, Saudi Arabia.

Keyword extraction refers to the process of detecting the most relevant terms and expressions in a given text in a timely manner. In the information explosion era, keyword extraction has attracted increasing attention. The importance of keyword extraction in text summarization, text comparisons, and document categorization has led to an emphasis on graph-based keyword extraction techniques because they can capture more structural information compared to other classic text analysis methods. Read More

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Automatic extraction and stenosis evaluation of coronary arteries in invasive coronary angiograms.

Comput Biol Med 2021 Jul 21;136:104667. Epub 2021 Jul 21.

Department of Applied Computing, Michigan Technological University, Houghton, MI, 49931, USA; Center of Biocomputing and Digital Health, Michigan Technological University, Houghton, MI, 49931, USA. Electronic address:

Background: Coronary artery disease (CAD) is the leading cause of death in the United States (US) and a major contributor to healthcare cost. Accurate segmentation of coronary arteries and detection of stenosis from invasive coronary angiography (ICA) are crucial in clinical decision making.

Purpose: We aim to develop an automatic method to extract coronary arteries by deep learning and detect arterial stenosis from ICAs. Read More

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Pooled SARS-CoV-2 antigen tests in asymptomatic children and their caregivers: Screening for SARS-CoV-2 in a pediatric emergency department.

Am J Infect Control 2021 Jul 24. Epub 2021 Jul 24.

Department of Gastroenterology, Hepatology, Pneumology and Infectious diseases, Katharinenhospital, Klinikum Stuttgart, Kriegsbergstraße 60, 70174 Stuttgart, Germany; Department of Hospital Hygiene, Klinikum Stuttgart, Kriegsbergstraße 60, 70174 Stuttgart Germany; Department I of Internal Medicine, Division of Infectious Diseases, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany. Electronic address:

Background: Universal admission screening for SARS-CoV-2 in children and their caregivers (CG) is critical to prevent hospital outbreaks. We evaluated pooled SARS-CoV-2 antigen tests (AG) to identify infectious individuals while waiting for PCR test results.

Methods: This single-center study was performed from November 5, 2020 to March 1, 2021. Read More

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Microwave Assisted Extraction for Quantification of Microplastics Using Pyrolysis-GC/MS.

Environ Toxicol Chem 2021 Jul 27. Epub 2021 Jul 27.

Department of Ecology and Evolutionary Biology, University of Toronto, 25 Willcocks Street, Toronto, ON, M5S 3B2, Canada.

Microplastics (MP) are now recognized as a persistent and global pollutant. To quantitively measure MPs in environmental matrices, several techniques are used - including new methods using Pyrolysis-Gas Chromatography/Mass Spectrometry. In this study, a new extraction method using Microwave-Assisted Extraction (MAE) combined with Py-GC/MS was developed to extract and quantify a wide range of plastic polymers and validated using different environmental matrices. Read More

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Ultrasound versus routine care before instrumental vaginal delivery: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2021 Jul 27. Epub 2021 Jul 27.

Department of Obstetrics and Gynecology, University of Chieti, Chieti, Italy.

Introduction: The objective was to report the role of ultrasound in affecting maternal and perinatal outcome in women undergoing instrumental vaginal delivery.

Material And Methods: MEDLINE, Embase, CINAHL, Google Scholar and ClinicalTrial.gov databases were searched. Read More

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Introducing the Rapid Alert Supply Network Extractor (RASNEX) tool to mine supply chain information from food and feed contamination notifications in Europe.

PLoS One 2021 27;16(7):e0254301. Epub 2021 Jul 27.

German Federal Institute for Risk Assessment, Berlin, Germany.

Background: During food or feed contamination events, it is of utmost importance to ensure their rapid resolution to minimize impact on human health, animal health and finances. The existing Rapid Alert System for Food and Feed (RASFF) is used by the European Commission, national competent authorities of member countries and the European Food Safety Authority to report information on any direct or indirect human health risk arising from food or feed, or serious risks to animal health or the environment in relation to feed. Nevertheless, no methods exist to to collectively evaluate this vast source of supply chain information. Read More

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Identification for surrogate drought tolerance in maize inbred lines utilizing high-throughput phenomics approach.

PLoS One 2021 27;16(7):e0254318. Epub 2021 Jul 27.

Department of Botany, Hindu College Moradabad (Mahatma Jyotiba Phule Rohilkhand University Bareilly), Moradabad, India.

Screening for drought tolerance requires precise techniques like phonemics, which is an emerging science aimed at non-destructive methods allowing large-scale screening of genotypes. Large-scale screening complements genomic efforts to identify genes relevant for crop improvement. Thirty maize inbred lines from various sources (exotic and indigenous) maintained at Dryland Agriculture Research Station were used in the current study. Read More

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Discriminative Cervical Lesion Detection in Colposcopic Images with Global Class Activation and Local Bin Excitation.

IEEE J Biomed Health Inform 2021 Jul 27;PP. Epub 2021 Jul 27.

Accurate cervical lesion detection (CLD) methods using colposcopic images are highly demanded in computer-aided diagnosis (CAD) for automatic diagnosis of High-grade Squamous Intraepithelial Lesions (HSIL). However, compared to natural scene images, the specific characteristics of colposcopic images, such as low contrast, visual similarity, and ambiguous lesion boundaries, pose difficulties to accurately locating HSIL regions and also significantly impede the performance improvement of existing CLD approaches. To tackle these difficulties and better capture cervical lesions, we develop novel feature enhancing mechanisms from both global and local perspectives, and propose a new discriminative CLD framework, called CervixNet, with a Global Class Activation (GCA) module and a Local Bin Excitation (LBE) module. Read More

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Deep Supervised Domain Adaptation for Pneumonia Diagnosis from Chest X-ray Images.

IEEE J Biomed Health Inform 2021 Jul 27;PP. Epub 2021 Jul 27.

Pneumonia is one of the most common treatable causes of death, and early diagnosis allows for early intervention. Automated diagnosis of pneumonia can therefore improve outcomes. However, it is challenging to develop high performance deep learning models due to the lack of well-annotated data for training. Read More

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Evaluation of spin in the abstracts of systematic reviews and meta-analyses focused on the treatment of obesity.

Obesity (Silver Spring) 2021 Aug;29(8):1285-1293

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.

Objective: Spin, i.e., the misrepresentation of research findings, has the potential to affect patient care. Read More

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Isolation and Analysis of MicroRNAs from Extracellular Vesicles of the Parasitic Model Nematodes Nippostrongylus brasiliensis and Trichuris muris.

Methods Mol Biol 2021 ;2369:319-332

Institute of Parasitology, University of Zurich, Zurich, Switzerland.

The identification, detection, and use of small RNA species have rapidly gained interest-especially to study parasite-host interactions. Parasite-to-host communication is contributed by small secreted extracellular vesicle (EV)-derived nucleic acid species. In particular, microRNAs (miRNAs) and small interfering RNAs can regulate the host response by targeting cells at both transcriptional and posttranscriptional levels. Read More

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January 2021

Transcriptional Analysis of Tightly Synchronized Plasmodium falciparum Intraerythrocytic Stages by RT-qPCR.

Methods Mol Biol 2021 ;2369:165-185

ISGlobal, Hospital Clínic-Universitat de Barcelona, Barcelona, Catalonia, Spain.

In Plasmodium falciparum, the parasite responsible for the most severe forms of human malaria, many fundamental processes are controlled at the transcriptional level. Studies on diverse aspects of basic parasite biology as well as molecular epidemiology studies often rely on the ability to accurately measure transcript levels, but this is complicated by the cyclic expression patterns of the majority of malaria parasite genes. Here, we provide a complete workflow to measure transcript levels in P. Read More

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January 2021

An Illumina MiSeq-Based Amplicon Sequencing Method for the Detection of Mixed Parasite Infections Using the Blastocystis SSU rRNA Gene as an Example.

Methods Mol Biol 2021 ;2369:67-82

United States Department of Agriculture, Agricultural Research Service, Environmental Microbial Food Safety Laboratory, Beltsville, MD, USA.

Parasite mixed infections remain a relatively unexplored field in part due to the difficulties of unraveling complex mixtures of parasite DNA using classical methods of sequencing. Next-generation amplicon sequencing (NGS) is a powerful tool for exploring mixed infections of multiple genetic variants of the same parasite in clinical, environmental (water or soil), or food samples. Here, we provide a method for NGS-based detection of mixed parasite infections which uses the Blastocystis SSU rRNA gene as an example and includes steps for parasite concentration, DNA extraction, sequencing library preparation, and bioinformatic analysis. Read More

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January 2021

Sequencing and Reconstructing Helminth Mitochondrial Genomes Directly from Genomic Next-Generation Sequencing Data.

Methods Mol Biol 2021 ;2369:27-40

AgResearch Limited, Grasslands Research Centre, Palmerston North, New Zealand.

We present a detailed method for extraction of high-molecular weight genomic DNA suitable for numerous DNA sequencing applications, and a straightforward in silico approach for reconstructing novel mitochondrial (mt) genomes directly from total genomic DNA extracts derived from next-generation sequencing (NGS) data sets. The in silico post-sequencing pipeline described is fast, accurate, and highly efficient, with modest memory requirements that can be performed using a standard desktop computer. The approach is particularly effective for obtaining mitochondrial genomes for species with little or no mitochondrial sequence information currently available and overcomes many of the limitations of traditional strategies. Read More

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January 2021

Does This Adult Patient Have Hypertension?: The Rational Clinical Examination Systematic Review.

JAMA 2021 Jul;326(4):339-347

Department of Medicine, Division of General Internal Medicine and Clinical Epidemiology, University of North Carolina at Chapel Hill.

Importance: Office blood pressure (BP) measurements are not the most accurate method to diagnose hypertension. Home BP monitoring (HBPM) and 24-hour ambulatory BP monitoring (ABPM) are out-of-office alternatives, and ABPM is considered the reference standard for BP assessment.

Objective: To systematically review the accuracy of oscillometric office and home BP measurement methods for correctly classifying adults as having hypertension, defined using ABPM. Read More

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Factors that influence international nursing students' experiences and perceptions of their learning environments: a scoping review protocol.

JBI Evid Synth 2021 Jul 26. Epub 2021 Jul 26.

Curtin School of Nursing, Curtin University, Perth, WA, Australia Western Australian Group for Evidence Informed Healthcare Practice: A JBI Centre of Excellence, Curtin University, Perth, WA, Australia Research Unit, St John of God Midland Hospital, St John of God Healthcare, Perth, WA, Australia.

Objective: The objective of this review is to explore the research on factors that influence international undergraduate nursing students' experiences and perceptions of their learning environment.

Introduction: International nursing students bring valuable cultural and economic opportunities to universities and health care. It is important their clinical learning experiences are positive. Read More

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Deteriorated regional calf microcirculation measured by contrast-free MRI in patients with diabetes mellitus and relation with physical activity.

Diab Vasc Dis Res 2021 Jul-Aug;18(4):14791641211029002

The Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA.

Objective: To evaluate regional calf muscle microcirculation in people with diabetes mellitus (DM) with and without foot ulcers, compared to healthy control people without DM, using contrast-free magnetic resonance imaging methods.

Methods: Three groups of subjects were recruited: non-DM controls, DM, and DM with foot ulcers (DM + ulcer), all with ankle brachial index (ABI) > 0.9. Read More

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Resonance frequency analysis with two different devices after conventional implant placement with ridge preservation: A prospective pilot cohort study.

Clin Implant Dent Relat Res 2021 Jul 26. Epub 2021 Jul 26.

Synapse Research Institute, Maastricht, the Netherlands.

Background: Primary and secondary implant stability is of high importance for survival and success of dental implants in the short and long term. Measurements of implant stability during healing provide the opportunity to monitor the course of the osseointegration process.

Purpose: To compare implant stability quotient (ISQ) by resonance frequency analysis (RFA), recorded with two different devices after implant placement. Read More

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Multimodality-based knee joint modeling method with bone and cartilage structures for total knee arthroplasty.

Int J Med Robot 2021 Jul 26:e2316. Epub 2021 Jul 26.

School of Mechanical Engineering and Automation, Beihang University, Beijing, China.

Objective: We propose a robust and accurate knee joint modeling method with bone and cartilage structures to enable accurate surgical guidance for knee surgery.

Methods: A multimodality registration strategy is proposed to fuse MR and CT images of the femur and tibia separately to remove spatial inconsistency caused by knee bending in CT/MR scans. Automatic segmentation of the femur, tibia, and cartilages is carried out with ROI clustering and intensity analysis based on the multimodal fusion of images. Read More

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Forks in the road: Definitions of response, remission, recovery, and other dichotomized outcomes in randomized controlled trials for adolescent depression. A scoping review.

Depress Anxiety 2021 Jul 26. Epub 2021 Jul 26.

Department of Psychiatry, Child and Youth Mental Health, University of Toronto, Toronto, Ontario.

Background: Definitions of dichotomous outcome terms, such as "response," "remission," and "recovery" are central to the design, interpretation, and clinical application of randomized controlled trials of adolescent depression interventions. Accordingly, this scoping review was conducted to document how these terms have been defined and justified in clinical trials.

Method: Bibliographic databases MEDLINE, Embase, APA PsycInfo, and CINAHL were searched from inception to February 2020 for randomized controlled trials evaluating treatments for adolescent depression. Read More

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Determining a safe upper limit of oxygen supplementation for adult patients: a systematic review.

BMJ Open 2021 Jul 26;11(7):e045057. Epub 2021 Jul 26.

Department of Anaesthesia, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark.

Objective: This systematic review aimed to describe the connection between the inspired oxygen fraction and pulmonary complications in adult patients, with the objective of determining a safe upper limit of oxygen supplementation.

Methods: MEDLINE and Embase were systematically searched in August 2019 (updated July 2020) for studies fulfilling the following criteria: intubated adult patients (opulation); high fractions of oxygen (ntervention) versus low fractions of (omparison); atelectasis, acute respiratory distress syndrome (ARDS), pneumonia and/or duration of mechanical ventilation (utcome); original studies both observational and interventional (tudies). Screening, data extraction and risk of bias assessment was done by two independent reviewers. Read More

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[Detect 15 pesticides fungicide in edible fungi by multiplug filtration clean-up pretreatment technology with ultra-high performance liquid chromatography-tandem mass spectrometry].

Wei Sheng Yan Jiu 2021 Jul;50(4):633-640

Beijing Center for Disease Control and Prevention, Beijing 100013, China.

Objective: To establish a method for determination of 15 pesticides residue in edible fungi by multiplug filtration clean-up(m-PFC) pretreatment technique with ultra-high performance liquid chromatography-tandem triple quadruple mass spectrometry(UPLC-MS/MS).

Methods: The interferences of edible fungus samples were removed by extracting with acetonitrile and filtration type extraction column, which were fat, carbohydrates, water-soluble vitamins. Samples were separated with column of Waters ACQUITY UPLC®HSS T3(2. Read More

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[Determination of chlorate and perchlorate in infant formula by ultra-high performance liquid chromatography-tandem mass spectrometry].

Wei Sheng Yan Jiu 2021 Jul;50(4):625-632

Fujian Provincial Key Laboratory of Zoonosis Research, Fujian Center for Disease Control & Prevention, Fuzhou 350001, China.

Objective: To establish a method for determination of perchlorate and chlorate in infant formula by ultra-high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS).

Methods: Chlorate-~(18)O_3 and perchlorate-~(18)O_4 were added to the samples, and the filtrate was collected and analyzed by UPLC-MS/MS by vortex mixing, extraction, centrifugation and filtration. The mobile phase was 20 mmol/L ammonium formate and acetonitrile. Read More

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[Determination of quinoxalines veterinary drug residues in food products of animal origin by high performance liquid chromatography-tandem mass spectrometry].

Hua Yin Weiming Lu

Wei Sheng Yan Jiu 2021 Jul;50(4):620-624

Changshu Provincial Center for Disease Control and Prevention, Changshu 215500, China.

Objective: To establish a high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)method for simultaneous determination of olaquindox, quinoxaline-2-carboxylic acid, 3-methyl-quinoxaline-2-carboxylic acid in food products of animal origin.

Methods: Samples were extracted with ethyl acetate-0.1 mol/L sodium dihydrogen phosphate(1∶9, V/V) solution in water bath at 40 ℃, purified by solid phase extraction column(olaquindox uses HLB SPE cartridge, quinoxaline-2-carboxylic acid and 3-methyl-quinoxaline-2-carboxylic acid use MAX SPE cartridge), evaporated by concentrator, and dissolved by mobile phase. Read More

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[Determination of vitamin A, vitamin E isomers and cholesterol in foods by reversed-phase high-performance liquid chromatography].

Wei Sheng Yan Jiu 2021 Jul;50(4):615-619

Center for Disease Control and Prevention of Shaanxi Province, Xi'an 710054, China.

Objective: To establish a method for simultaneous analysis of vitamin A, three vitamin E isomers and cholesterol in meat products by reversed-phase high-performance liquid chromatography. This method is used to determine the contents of the corresponding nutrients in several meat products.

Methods: The sample was pretreated with saponification and liquid-liquid extraction, then separated on Waters Symmetry C_(18) column(4. Read More

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A new variant of deep belief network assisted with optimal feature selection for heart disease diagnosis using IoT wearable medical devices.

Comput Methods Biomech Biomed Engin 2021 Jul 26:1-25. Epub 2021 Jul 26.

Department of Information Technology, Noorul Islam Centre for Higher Education, Thuckalay, Kanyakumari, Tamil Nadu, India.

In this paper, the information related to heart disease using IoT wearable devices is collected from any benchmark site, which is publicly available. With the collected data, feature extraction process is performed initially, in which heart rate, zero crossing rate, and higher order statistical features like standard deviation, median, skewness, kurtosis, variance, mean, peak amplitude, and entropy are extracted. For acquiring most significant features, the optimal feature selection process is implemented. Read More

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mHealth technologies used to capture walking and arm use behavior in adult stroke survivors: a scoping review beyond measurement properties.

Disabil Rehabil 2021 Jul 23:1-13. Epub 2021 Jul 23.

Biokinesiology and Physical Therapy, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.

Purpose: We aimed to provide a critical review of measurement properties of mHealth technologies used for stroke survivors to measure the amount and intensity of functional skills, and to identify facilitators and barriers toward adoption in research and clinical practice.

Materials And Methods: Using Arksey and O'Malley's framework, two independent reviewers determined eligibility and performed data extraction. We conducted an online consultation survey exercise with 37 experts. Read More

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Can Kinesio taping improve discomfort after mandibular third molar surgery? A systematic review and meta-analysis.

Clin Oral Investig 2021 Jul 23. Epub 2021 Jul 23.

Department of Orthodontics, Ningbo Stomatology Hospital, 315000, Ningbo, China.

Objective: The purpose of this study was to evaluate whether Kinesio taping (KT) can improve patient discomfort after mandibular third molar surgery.

Materials And Methods: This systematic review and meta-analysis was conducted according to the PICO strategy. We searched 4 databases for related articles. Read More

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LC-ESI-MS/MS Simultaneous Analysis Method Coupled with Cation-Exchange Solid-Phase Extraction for Determination Of Pyrrolizidine Alkaloids on 5 Kinds of Herbal Medicines.

J AOAC Int 2021 Jul 23. Epub 2021 Jul 23.

Herbal Medicine Research Division, National Institute of Food and Drug Safety Evaluation, Chungbuk, 28159, Republic of Korea.

Background: Pyrrolizidine alkaloids (PAs) are naturally occurring plant toxins associated with potential hepatic and carcinogenic diseases in humans and animals. The concern of PAs has been increased as the consumption of herbal medicines is increased.

Objective: This study aimed to develop and validate a sensitive analytical method to determine 28 PAs in 5 herbal medicines using liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). Read More

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Synovial mesenchymal stem cell-derived extracellular vesicles containing microRNA-26a-5p ameliorate cartilage damage of osteoarthritis.

J Gene Med 2021 Jul 23:e3379. Epub 2021 Jul 23.

Shanghai East Hospital, Tongji University, School of Medicine, Shanghai, China.

Background: Osteoarthritis (OA) is a degenerative disease characterized by cartilage damage. We aim at an improved understanding of the protective mechanism of synovial mesenchymal stem cells (SMSCs)-derived extracellular vesicles (EVs) in cartilage damage of OA.

Methods: SMSCs and SMSC-EVs were isolated from synovial biopsies of patients without OA and identified. Read More

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