26,182 results match your criteria extracted growth


Production of polyhydroxybutyrate by the cyanobacterium cf. Anabaena sp.

Int J Biol Macromol 2021 Sep 15. Epub 2021 Sep 15.

Centro Interdipartimentale di Ricerca Industriale Fonti Rinnovabili, Ambiente, Mare ed Energia (CIRI-FRAME), Università di Bologna, via S. Alberto 163, Ravenna, Italy; Dipartimento di Chimica "Giacomo Ciamician", Università di Bologna, via S. Alberto 163, Ravenna, Italy. Electronic address:

Polyhydroxybutyrate (PHB) production by the cyanobacterium cf. Anabaena sp. was here studied by varying the medium composition and the carbon source used to induce mixotrophic growth conditions. Read More

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September 2021

Accelerated pubertal onset in short children with delayed bone age.

J Pediatr Endocrinol Metab 2021 Sep 20. Epub 2021 Sep 20.

Division of Pediatric Endocrinology and Metabolism, Children's Medical Center, Osaka City General Hospital, Osaka, Japan.

Objectives: Constitutional delay of growth (CDG) is usually associated with a delay in pubertal onset (CDGP) and a catch-up growth after puberty. Some individuals, however, have earlier-than-expected pubertal onset resulting in a shorter adult height. We investigated the current incidence of such individuals and that of 30 years ago. Read More

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September 2021

Stable isotope tracing to assess tumor metabolism in vivo.

Nat Protoc 2021 Sep 17. Epub 2021 Sep 17.

Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Cancer cells undergo diverse metabolic adaptations to meet the energetic demands imposed by dysregulated growth and proliferation. Assessing metabolism in intact tumors allows the investigator to observe the combined metabolic effects of numerous cancer cell-intrinsic and -extrinsic factors that cannot be fully captured in culture models. We have developed methods to use stable isotope-labeled nutrients (e. Read More

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September 2021

14-year trends and resistance patterns of blood and cerebrospinal fluid cultures in children under three years old.

J Infect 2021 Sep 14. Epub 2021 Sep 14.

Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom; NIHR Oxford Biomedical Research Centre, Level 2, Children's Hospital, Oxford, United Kingdom; Paediatric Infectious Diseases Research Group, Institute of Infection and Immunity, St George's, University of London, London, United Kingdom. Electronic address:

Objectives: Bacterial infections are a major cause of UK paediatric hospitalisations, yet longitudinal data on causative organisms or antimicrobial resistance are scarce. This retrospective analysis describes trends in blood and cerebrospinal fluid (CSF) cultures and resistance patterns in children under three years old from a large UK centre.

Methods: All culture results, and resistance data for Gram-negative rods (GNR) in blood cultures, collected between January 2005 and December 2018 were extracted from Oxford University Hospitals NHS Foundation Trust microbiology database. Read More

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September 2021

[Human colorectal cancer cells induce fibroblasts to secrete stromal cell-derived factor 1 (SDF-1) to stimulate cancer cell migration].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2021 Sep;37(9):821-827

The Second Affiliated Hospital, Xi'an Medical University, Xi'an 710038, China. *Corresponding author, E-mail:

Objective To investigate the inflammatory induction effect of HCT-116 colorectal cancer cells on normal fibroblasts (NFs) extracted from para-cancerous tissues and the effect of cancer associated fibroblasts (CAFs) on cancer cell migration and its potential mechanism. Methods The enzyme digestive method was used to extract NFs and CAFs from tissues. Spatial Gene Expression Dataset was downloaded to analyze transcriptional expression levels of inflammatory factors including transforming growth factor β (TGF-β), tumor necrosis factor-α (TNF-α), C-X-C motif chemokine ligand 2 (CXCL2), interleukin-1β (IL-1β), and stromal cell-derived factor-1 (SDF-1). Read More

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September 2021

Mesoporous silica particles functionalized with newly extracted fish oil ([email protected]) inhibit lung cancer cell growth.

Nanomedicine (Lond) 2021 Sep 17. Epub 2021 Sep 17.

Istituto per la Ricerca e l'Innovazione Biomedica, CNR, Via U. La Malfa 153, Palermo, 90146, Italy.

To assess whether [email protected] microparticles - fish oil from anchovy fillet leftovers (AnchoisOil) encapsulated within mesoporous silica particles - are effective in promoting antitumor effects in lung cancer cells. Three human non-small-cell lung cancer cell lines (A549, Colo 699 and SK-MES-1) were used. Cells were treated with AnchoisOil dispersed in ethanol (10 and 15 μg/ml) or encapsulated in silica and further formulated in aqueous ethanol. Read More

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September 2021

Long-term sevoflurane exposure reduces the differentiation potential and hypoxia tolerance potential of neural stem cells.

Int J Dev Neurosci 2021 Sep 16. Epub 2021 Sep 16.

Tianjin Key Laboratory of Epigenetics for Organ Development of Premature Infants, The Fifth Central Hospital of Tianjin, Tianjin, China.

Purpose: To investigate the effect of prolonged sevoflurane (SEV) exposure on differentiation potential and hypoxia tolerance of neural stem cells (NSCs).

Materials And Methods: NSCs were extracted from 15-day fetal mice. After sub-culture, Sevoflurane exposure treatment was performed. Read More

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September 2021

Associations between the exposure to organophosphate flame retardants during early pregnancy and the risk of spontaneous abortion based on metabolomics combined with tandem mass spectrometry.

Ann Transl Med 2021 Aug;9(16):1305

Department of Pharmacy, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

Background: As potential substitutes for polybrominated diphenyl ethers (PBDEs), organophosphate flame retardants (OPFRs) have been frequently detected in the environment. They have been suggested to impair fetal growth and development in toxicological studies. However, there are few studies on their maternal effects before or during early pregnancy. Read More

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Bioefficacy, residue dynamics and dietary risk assessment of gibberellic acid in improving the potential yield of tomato (Solanum lycopersicum L.).

Environ Monit Assess 2021 Sep 15;193(10):652. Epub 2021 Sep 15.

Network Project On Pesticide Residues, Directorate of Research, Bidhan Chandra Krishi Viswavidyalaya, Kalyani, Nadia, West Bengal, India.

The increasing use of gibberellic acid (GA) to promote fruit growth and yield has necessitated research into its trace level determination and estimation in harvested product. The phytohormone has increased the tomato yield (tonne ha) up to 24.7% with uniform fruit shape, size colour and lustre. Read More

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September 2021

Comparative Proteomics at the Critical Node of Vigor Loss in Wheat Seeds Differing in Storability.

Front Plant Sci 2021 30;12:707184. Epub 2021 Aug 30.

National Crop Genebank, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing, China.

The critical node (CN, 85% germination) of seed viability is an important threshold for seed regeneration decisions after long-term conservation. Dependent on the germplasm, the storage period until CN is reached varies and information on the divergence of the proteomic profiles is limited. Therefore, the study aims to identify key proteins and mechanisms relevant for a long plateau phase and a late CN during artificial seed aging of wheat. Read More

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Children's psychosocial and behavioural consequences during their siblings' hospitalisation: A qualitative content analysis from caregivers' perspectives.

J Clin Nurs 2021 Sep 14. Epub 2021 Sep 14.

School of Nursing, Graduate School of Nursing, Mukogawa Women's University, Nishinomiya, Hyogo, Japan.

Aims And Objectives: This study aimed to comprehensively describe the psychosocial and behavioural consequences experienced by siblings of hospitalised children from the caregivers' perspective.

Background: After children are diagnosed with a major illness, their siblings may begin to exhibit psychological and behavioural problems, coupled with decreased quality of life.

Design: This study employed qualitative content analysis to describe the perspectives of 147 caregivers of siblings of hospitalised children, following the COREQ guidelines. Read More

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September 2021

Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog.

Regen Ther 2021 Dec 1;18:309-315. Epub 2021 Sep 1.

Department of Spine Surgery, Guizhou Province Osteological Hospital, Guiyang, 550002, China.

Objective: The loss of neural ability leading to subsequent diminishing of motor function and the impairment below the location of the injury is a result of the SCI (Spinal Cord Injury). Among the many therapeutic agents for SCI, the exosomes considered as extracellular vesicles seem to be the most promising. Sonic Hedgehog (Shh) is an exosome-carrying protein. Read More

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December 2021

Assessing the optimal time interval between growth measurements using a combined data set of weights and heights from 5948 infants.

Arch Dis Child 2021 Sep 14. Epub 2021 Sep 14.

Population Policy and Practice department, UCL GOS Institute of Child Health, London, UK.

Background: Current guidance on the optimum interval between measurements in infancy is not evidence based. We used routine data to explore how measurement error and short-term variation ('noise') might affect interpretation of infant weight and length gain ('signal') over different time intervals.

Method: Using a database of weights and lengths from 5948 infants aged 0-12 months, all pairs of measurements per child 2, 4 and 8 weeks apart were extracted. Read More

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September 2021

Cancer derived exosomes induce macrophages immunosuppressive polarization to promote bladder cancer progression.

Cell Commun Signal 2021 Sep 14;19(1):93. Epub 2021 Sep 14.

Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.

Background: Exosomes mediated crosstalk between tumor cells and other stromal cells including tumor associated macrophages plays an essential role in reprogramming tumor microenvironment (TME) to facilitate tumor progression. However, the mechanism of tumor derived exosomes promotes bladder cancer progression have not been defined.

Methods: Exosomes were extracted from bladder cancer cells MB49 conditioned medium by ultracentrifugation. Read More

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September 2021

Essential oils as alternative promising anti-Candidal agents: progress and prospects.

Curr Pharm Des 2021 Sep 14. Epub 2021 Sep 14.

Amity Institute of Biotechnology, Amity University Haryana, Manesar, Gurugram- 122413. India.

Candida albicans is one of the main agents responsible for opportunistic pathogenic infections. The progressive emergence of fungal resistance to conventional antibiotics and its side effects as well as treatment costs are considered as major limitations for antifungal drugs. It has drawn scientists' attention to search for potential substitution and therapeutic reliable alternatives for the antifungal compounds from sources like medicinal plants, which contain numerous bioactive compounds such as essential oils. Read More

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September 2021

Toosendanin Shows Potent Efficacy Against Human Ovarian Cancer through Caspase-Dependent Mitochondrial Apoptotic Pathway.

Am J Chin Med 2021 Sep 11:1-16. Epub 2021 Sep 11.

Department of Traditional Chinese and Western Medicine, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan, P. R. China.

Toosendanin (TSN) is a triterpenoid extracted from the bark or fruits of Sieb et Zucc, which is a traditional Chinese medicine and mainly grows in China and India. TSN has been verified to possess antitumor activities on various human cancers, whereas the effects of TSN on ovarian cancer (OC) has not been reported yet. Here, TSN was shown to significantly inhibit proliferation of SKOV3 and OVCAR3 cell lines in a dose- and time-dependent manner. Read More

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September 2021

Prediction for pathological and immunohistochemical characteristics of triple-negative invasive breast carcinomas: the performance comparison between quantitative and qualitative sonographic feature analysis.

Eur Radiol 2021 Sep 14. Epub 2021 Sep 14.

Shanghai Key Laboratory of Multidimensional Information Processing, East China Normal University, #500 Dongchuan Rd., Shanghai, 200241, China.

Objective: Sonographic features are associated with pathological and immunohistochemical characteristics of triple-negative breast cancer (TNBC). To predict the biological property of TNBC, the performance using quantitative high-throughput sonographic feature analysis was compared with that using qualitative feature assessment.

Methods: We retrospectively reviewed ultrasound images, clinical, pathological, and immunohistochemical (IHC) data of 252 female TNBC patients. Read More

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September 2021

Simultaneous Detection of Multiple Plant Growth Regulator Residues in Cabbage and Grape Using an Optimal QuEChERS Sample Preparation and UHPLC-MS/MS Method.

J AOAC Int 2021 Sep 14. Epub 2021 Sep 14.

Shanghai Agricultural Technology Extension and Service Center, Shanghai, 201103, China.

Background: At present, PGRs are widely used in agricultural and forestry production in the world, PGRs, like the traditional pesticides have certain toxicity, naively excessive applied them will cause the acute and chronic poisoning of humans and animals, potential harm to human health.

Objectives: In order to assess, prevent and control the residues of plant growth regulators (PGRs) in fruits and vegetables, a set of easy, sensitive, quick, cheap, effective, reliable and safe analytical method that simultaneously detects multiple PGRs residues is urgently needed for the inspection departments of agricultural product's quality safety.

Methods: In this study, grape (representative of fruit) and cabbage (representative of vegetable) were used as the detected objects. Read More

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September 2021

Miniaturized multiresidue method for determination of 267 pesticides, their metabolites and polychlorinated biphenyls in low mass beebread samples by liquid and gas chromatography coupled with tandem mass spectrometry.

Talanta 2021 Dec 20;235:122721. Epub 2021 Jul 20.

Department of Pharmacology and Toxicology, National Veterinary Research Institute, Aleja Partyzantów 57, 24-100, Puławy, Poland.

Current work presents developed and validated miniaturized method for residue analysis of 261 pesticides and their metabolites as well as 6 congeners of non-dioxin like polychlorinated biphenyls (ndl-PCB) in a very low mass beebread sample. Sample preparation is based on modified QuEChERS protocol with all steps miniaturized to enable multiresidue analysis of sample with extremely low weight. Sample of beebread (0. Read More

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December 2021

Extracted features of national and continental daily biweekly growth rates of confirmed COVID-19 cases and deaths via Fourier analysis.

Authors:
Ray-Ming Chen

Math Biosci Eng 2021 07;18(5):6216-6238

Department of Mathematics and Statistics, Baise University, 21 Zhongshan No. 2 Road, Basie 533000, China.

Aims: By associating features with orthonormal bases, we analyse the values of the extracted features for the daily biweekly growth rates of COVID-19 confirmed cases and deaths on national and continental levels.

Methods: By adopting the concept of Fourier coefficients, we analyse the inner products with respect to temporal and spatial frequencies on national and continental levels. The input data are the global time series data with 117 countries over 109 days on a national level; and 6 continents over 447 days on a continental level. Read More

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Automatic fetal movement recognition from multi-channel accelerometry data.

Comput Methods Programs Biomed 2021 Aug 30;210:106377. Epub 2021 Aug 30.

University of Queensland Centre for Clinical Research, The University of Queensland, Brisbane, Australia.

Background And Objective: Significant health care resources are allocated to monitoring high risk pregnancies to minimize growth compromise, reduce morbidity and prevent stillbirth. Fetal movement has been recognized as an important indicator of fetal health. Studies have shown that 25% of pregnancies with decreased fetal movement in the third trimester led to poor outcomes at birth. Read More

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First report of root rot caused by () on hydroponically grown collard greens ().

Plant Dis 2021 Sep 13. Epub 2021 Sep 13.

Tri Cal, TriCal Diagnostics, 8100 Arroyo Circle, Gilroy, California, United States, 95020;

Collards (Brassica oleracea var. acephala) are grown throughout the United States. Hydroponic greens are more common now due to technological advances lowering the cost and increasing the efficacy of production. Read More

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September 2021

First Report of Southern Blight Caused by on in China.

Plant Dis 2021 Sep 13. Epub 2021 Sep 13.

Shanghai Academy of Landscape Architecture Science and Planning, Institute of Plant Protection, Shanghai, Shanghai, China.

is an evergreen shrub-vine in the family Celastraceae, widely used as a groundcover or a vine to climb walls, or traditional herbal medicine in China. In August 2019, typical southern blight symptoms that included basal stem rot and the presence of sclerotia in rotted tissue were observed on in Kunshan city, Jiangsu province, China. Disease incidence was estimated at approximately 15 to 20%; meanwhile, approximately 30 to 40% of diseased plants died. Read More

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September 2021

First Report of Causing Leaf Spot Disease on in China.

Plant Dis 2021 Sep 13. Epub 2021 Sep 13.

Guangxi University for Nationalities, 47874, Guangxi Colleges and Universities Key Laboratory of Utilization of Microbial and Botanical Resources, 188 Daxuedong Road, Nanning, Guangxi, China, 530006.

(Thunb.) Rchb. f. Read More

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September 2021

Economic growth target and environmental regulation intensity: evidence from 284 cities in China.

Environ Sci Pollut Res Int 2021 Sep 13. Epub 2021 Sep 13.

School of Economics and Finance, South China University of Technology, Panyu District, Guangzhou City, 510006, Guangdong, China.

Management of economic growth targets is a universal measure employed by worldwide governments for macroeconomic regulation. This paper aims to empirically investigate the impact of economic growth targets set by governments of prefecture-level cities on the environmental regulation intensity. We extracted panel data on annual economic growth targets and environmental regulation indicators from the government work reports (2009-2016) of 284 China's prefecture-level cities. Read More

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September 2021

Adipose-derived stem cells inhibit dermal fibroblast growth and induce apoptosis in keloids through the arachidonic acid-derived cyclooxygenase-2/prostaglandin E2 cascade by paracrine.

Burns Trauma 2021 11;9:tkab020. Epub 2021 Sep 11.

Department of Burn and Plastic Surgery, the Fourth Medical Centre, Chinese People's Liberation Army General Hospital, No. 51 Fucheng Road, Haidian District, Beijing, 100038, China.

Background: The clinical features of keloids consist of aberrant proliferation, secretion, differentiation and apoptosis of keloid dermis-derived fibroblasts (KFBs). Notably, the apoptosis rate of KFBs is lower than the proliferation rate. Though the anti-fibrotic effect of adipose-derived stem cells (ADSCs) on keloids has become a hot topic of research, the exact anti-fibrotic mechanism of the paracrine effect remains unclear. Read More

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September 2021

Baicalein Potentiated M1 Macrophage Polarization in Cancer Through Targeting PI3Kγ/ NF-κB Signaling.

Front Pharmacol 2021 25;12:743837. Epub 2021 Aug 25.

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.

Baicalein is one of the bioactive compounds extracted from . Recent studies indicated the antitumor effects of baicalein, however, the underlying mechanisms are needed to be further determined. In this study, we found that baicalein could inhibit the tumor growth in mice models of breast cancer and melanoma and worked as an immunomodulator to promote the infiltration of tumor-associated macrophages (TAMs) and skew the TAMs towards the M1-like phenotype. Read More

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Chinese Herbal Medicine Combined With First-Generation EGFR-TKIs in Treatment of Advanced Non-Small Cell Lung Cancer With EGFR Sensitizing Mutation: A Systematic Review and Meta-Analysis.

Front Pharmacol 2021 27;12:698371. Epub 2021 Aug 27.

Department of Oncology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) significantly improve prognosis of advanced NSCLC patients harboring EGFR sensitizing mutation. However, acquired resistance to EGFR-TKIs limits the good outcomes. Read More

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Cattail fibers as source of cellulose to prepare a novel type of composite aerogel adsorbent for the removal of enrofloxacin in wastewater.

Int J Biol Macromol 2021 Sep 9. Epub 2021 Sep 9.

School of Civil Engineering, Inner Mongolia University of Technology, Hohhot 010051, PR China.

In this study, cattail was researched as a natural cellulose source to extract cellulose. Dewaxing, alkali and bleaching treatments were carried out for the cattail fibers (CFs). The FTIR, SEM and XRD results indicated that hemicellulose and lignin were successfully removed from the CFs, and the content of cattail cellulose increased from 41. Read More

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September 2021

Intervention impact on alcohol use, alcohol harms, and a combination of both: A latent class, secondary analysis of results from a randomized controlled trial.

Drug Alcohol Depend 2021 Aug 5;227:108944. Epub 2021 Aug 5.

Department of Psychology, Royal College of Surgeons in Ireland, Beaux Lane House, Mercer Street, Dublin 2, Ireland. Electronic address:

Background: Alcohol use and alcohol-related harm (ARH) among adolescents places a substantial burden on health, and public services more generally. To date, attempts to intervene at a universal level have yielded results varying from iatrogenic to null, although some skill-enhancing universal interventions have successfully impacted drinking behaviors. One such intervention is SHAHRP. Read More

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