Ophthalmic Plast Reconstr Surg 2021 Jul 19. Epub 2021 Jul 19.
Department of Ophthalmology, Byers Eye Institute at Stanford University, Palo Alto, California, U.S.A. Department of Ophthalmology, Pacific Eye Associates and California Pacific Medical Center, San Francisco, California, U.S.A. Department of Medicine, Oregon Health & Science University, Portland, Oregon, U.S.A. Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, South Korea.
Purpose: Conventional modalities of external-beam radiation therapy (EBRT) are associated with high incidences of severe vision-threatening ocular and orbital toxicities when used to treat orbital malignancies. We investigate toxicities associated with high-dose volumetric modulated arc therapy (VMAT), a commonly used contemporary treatment modality for these tumors.
Methods: Retrospective analysis of malignant orbital tumors managed with adjuvant high-dose VMAT preceded by globe-salvaging surgical therapy (GST) or exenteration. Read More