2,734 results match your criteria extensive unilateral


Volume reduction without neuronal loss in the primate pulvinar complex following striate cortex lesions.

Brain Struct Funct 2021 Jul 29. Epub 2021 Jul 29.

Department of Physiology and Neuroscience Program, Biomedicine Discovery Institute, Monash University, Melbourne, VIC, 3800, Australia.

Lesions in the primary visual cortex (V1) cause extensive retrograde degeneration in the lateral geniculate nucleus, but it remains unclear whether they also trigger any neuronal loss in other subcortical visual centers. The inferior (IPul) and lateral (LPul) pulvinar nuclei have been regarded as part of the pathways that convey visual information to both V1 and extrastriate cortex. Here, we apply stereological analysis techniques to NeuN-stained sections of marmoset brain, in order to investigate whether the volume of these nuclei, and the number of neurons they comprise, change following unilateral long-term V1 lesions. Read More

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Ophthalmic artery occlusion due to orbital compartment syndrome after a frontotemporal craniotomy.

Indian J Ophthalmol Case Rep 2021 Apr-Jun;1(2):383-385. Epub 2021 Apr 1.

Department of Ophthalmology, New York University, New York, NY, USA.

A 32-year-old female with a right frontal lobe glioma underwent an elective frontotemporal craniotomy. One hour postoperatively, the patient developed a right orbital compartment syndrome (OCS) with unilateral acute vision loss, proptosis, afferent pupillary defect, and complete ophthalmoplegia. The patient underwent emergent lateral canthotomy and inferior cantholysis. Read More

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Thyroid surgery outcomes at a Children's Hospital: The value of a multidisciplinary team approach.

J Pediatr Surg 2021 Jul 7. Epub 2021 Jul 7.

Division of Pediatric Surgery, Department of Surgery, Baylor College of Medicine, Texas Children's Hospital, 6701 Fannin Street, Suite 1210, Houston, TX 77030, United States. Electronic address:

Background: Our purpose is to describe the structure, function and outcomes of our multidisciplinary pediatric thyroid program and to evaluate our experience in comparison to other high-volume centers.

Methods: We reviewed all thyroid operations performed 10/2012 through 09/2019, and examined number of cases per year, patient demographics, procedures, final diagnoses and results. Primary outcomes were hypoparathyroidism and recurrent laryngeal nerve (RLN) injury at 12 months. Read More

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Measurement of Cortical Atrophy and Its Correlation to Memory Impairment in Patients With Asymptomatic Carotid Artery Stenosis Based on VBM-DARTEL.

Front Aging Neurosci 2021 5;13:620763. Epub 2021 Jul 5.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Objective: Severe carotid artery stenosis (CAS) can lead to atrophy of gray matter (GM) and memory impairment; however, the underlying mechanism is unknown. Thus, we aimed to identify memory impairment and GM atrophy and explore the possible correlation between them in patients with asymptomatic severe CAS.

Methods: Twenty-four patients with asymptomatic severe CAS and 10 healthy controls completed the mini-mental state examination (MMSE) and clinical memory scale (CMS) and underwent 7T magnetic resonance imaging (MRI) scan. Read More

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Clinical features and imaging manifestations of retinoblastoma with hepatic metastasis.

Pediatr Blood Cancer 2021 Jul 22:e28959. Epub 2021 Jul 22.

Department of Pediatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Clinical data of five patients with hepatic metastases of retinoblastoma were analyzed retrospectively (two had bilateral tumors three had unilateral intraocular tumors). On computed tomography, multiple and single low-density foci were observed. Four patients had tumor remission, and one showed no response after chemotherapy. Read More

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Interrater and test-retest reliability of the Hand Assessment for Infants.

Dev Med Child Neurol 2021 Jul 5. Epub 2021 Jul 5.

Neuropediatric Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

Aim: To evaluate the interrater and test-retest reliability, standard error of measurement (SEM), and the smallest detectable difference (SDD) of the Hand Assessment for Infants (HAI).

Method: HAI assessments of 55 infants (26 females, 29 males), 25 with clinical signs of unilateral cerebral palsy (CP) and 30 typically developing (mean [SD] age 6.8mo [2. Read More

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Clinical and Radiological Characteristics Associated with Respiratory Failure in Unilateral Lateral Medullary Infarction.

J Stroke Cerebrovasc Dis 2021 Jun 27;30(9):105947. Epub 2021 Jun 27.

Department of Vascular Neurology and Intensive Therapy, University Medical Centre Ljubljana, Slovenia; Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Slovenia.

Background: The prognosis for unilateral lateral medullary infarction (ULMI) is generally good but may be aggravated by respiratory failure with fatal outcome. Respiratory failure has been reported in patients with severe bulbar dysfunction and large rostral medullary lesions, but its associated factors have not been systematically studied. We aimed to assess clinical and radiological characteristics associated with respiratory failure in patients with pure acute ULMI. Read More

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Staged reconstruction of unilateral neglected hip dislocation through total hip arthroplasty and subsequent intramedullary femoral lengthening.

Int Orthop 2021 Jun 28. Epub 2021 Jun 28.

Children's Orthopedics, Deformity Reconstruction and Foot Surgery, University Hospital of Muenster, Muenster, Germany.

Background And Purpose: Total hip arthroplasty (THA) is a successful approach to treat unilateral symptomatic neglected hip dislocation (NHD). However, the extensive leg length discrepancy (LLD) can hereby only be partially corrected. In case of residual LLD of more than 2 cm, subsequent femoral lengthening can be considered. Read More

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Phenotypic Spectrum of Peters Anomaly: Implications for Management.

Cornea 2021 Jun 29. Epub 2021 Jun 29.

Department of Ophthalmology, Rabin Medical Center, Schneider Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada; Peterborough Health Regional Center, Peterborough, ON, Canada; and Department of Ophthalmology and Vision Sciences, University of Alberta, Edmonton, AB, Canada.

Purpose: The aim of this study was to characterize the wide phenotypic spectrum of Peters anomaly and to suggest a management algorithm based on disease phenotype.

Methods: The charts of all children diagnosed with Peters anomaly between January 2000 and December 2013 were reviewed retrospectively. Anterior segment color photographs, anterior segment optical coherence tomography, and ultrasound biomicroscopy images were used to phenotype disease severity and to guide management. Read More

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Exploring partial intrinsic and extrinsic symmetry in 3D medical imaging.

Med Image Anal 2021 08 3;72:102127. Epub 2021 Jun 3.

Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA; Laboratory for Computer Aided Medical Procedures, Technical University of Munich, Munich, Germany.

We present a novel methodology to detect imperfect bilateral symmetry in CT of human anatomy. In this paper, the structurally symmetric nature of the pelvic bone is explored and is used to provide interventional image augmentation for treatment of unilateral fractures in patients with traumatic injuries. The mathematical basis of our solution is based on the incorporation of attributes and characteristics that satisfy the properties of intrinsic and extrinsic symmetry and are robust to outliers. Read More

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Effective connectivity and spatial selectivity-dependent fMRI changes elicited by microstimulation of pulvinar and LIP.

Neuroimage 2021 Jun 17;240:118283. Epub 2021 Jun 17.

Decision and Awareness Group, Cognitive Neuroscience Laboratory, German Primate Center, Leibniz Institute for Primate Research, Kellnerweg 4, Goettingen 37077, Germany; Department of Cognitive Neurology, University of Goettingen, Robert-Koch-Str. 40, Goettingen 37075, Germany; Leibniz ScienceCampus Primate Cognition, Kellnerweg 4, Goettingen 37077, Germany.

The thalamic pulvinar and the lateral intraparietal area (LIP) share reciprocal anatomical connections and are part of an extensive cortical and subcortical network involved in spatial attention and oculomotor processing. The goal of this study was to compare the effective connectivity of dorsal pulvinar (dPul) and LIP and to probe the dependency of microstimulation effects on task demands and spatial tuning properties of a given brain region. To this end, we applied unilateral electrical microstimulation in the dPul (mainly medial pulvinar) and LIP in combination with event-related BOLD fMRI in monkeys performing fixation and memory-guided saccade tasks. Read More

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Unilateral extensive purpura resulting from chronic iliofemoral deep venous thrombosis successfully treated by endovascular therapy with iliac vein stenting.

Kaohsiung J Med Sci 2021 Jun 17. Epub 2021 Jun 17.

Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

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A Pregnant Patient Presenting With Unilateral Sacroiliitis Following Dengue Hemorrhagic Fever: A Case Report.

Cureus 2021 May 10;13(5):e14946. Epub 2021 May 10.

Clinical Medicine, Teaching Hospital, Batticaloa, LKA.

Dengue virus infection is an arthropod-born infection with high global prevalence. A spectrum of clinical syndromes and complications were recognized following dengue fever that can range from undifferentiated fever to dengue shock syndrome. Neurological complications following dengue fever can extend to various sequelae, including transverse myelitis. Read More

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Unilateral Optic Neuritis Associated with SARS-CoV-2 Infection: A Rare Complication.

Am J Case Rep 2021 Jun 13;22:e931665. Epub 2021 Jun 13.

Department of Medicine, St. George's University School of Medicine, St. Georges, Grenada.

BACKGROUND Since the outbreak of the SARS-CoV-2 infection, extensive research has been conducted on the pulmonary implications of this novel disease. However, there has been limited data on the extrapulmonary manifestations. There have been few documented causes of optic involvement and little is understood about the pathophysiology around its presentation and the possible treatments to prevent long-term complications. Read More

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Chromosome-level genome assembly of a regenerable maize inbred line A188.

Genome Biol 2021 Jun 9;22(1):175. Epub 2021 Jun 9.

Department of Plant Pathology, Kansas State University, 4024 Throckmorton Center, Manhattan, KS, 66506-5502, USA.

Background: The maize inbred line A188 is an attractive model for elucidation of gene function and improvement due to its high embryogenic capacity and many contrasting traits to the first maize reference genome, B73, and other elite lines. The lack of a genome assembly of A188 limits its use as a model for functional studies.

Results: Here, we present a chromosome-level genome assembly of A188 using long reads and optical maps. Read More

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What is the effect of supervised rehabilitation regime vs. self-management instruction following unicompartmental knee arthroplasty? - a pilot study in two cohorts.

J Exp Orthop 2021 Jun 9;8(1):38. Epub 2021 Jun 9.

University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3B, 2200, Copenhagen N, Denmark.

Purpose: The optimal rehabilitation strategy after a unicompartmental knee arthroplasty (UKA) is unclear. This study aims to compare the effect of transitioning from a supervised to a self-management rehabilitation regime by pilot study of patient outcomes subsequent to UKA surgery.

Methods: Fifty consecutive patients scheduled to undergo unilateral UKA surgery at our institution between 22 February 2016 and 18of January 2017 were prospectively identified via local medical database and included. Read More

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Thickness accuracy of virtually designed patient-specific implants for large neurocranial defects.

J Anat 2021 Jun 4. Epub 2021 Jun 4.

Research Group Computed Tomography, University of Applied Sciences Upper Austria, Wels, Austria.

The combination of computer-aided design (CAD) techniques based on computed tomography (CT) data to generate patient-specific implants is in use for decades. However, persisting disadvantages are complicated design procedures and rigid reconstruction protocols, for example, for tailored implants mimicking the patient-specific thickness distribution of missing cranial bone. In this study we used two different approaches, CAD- versus thin-plate spline (TPS)-based implants, to reconstruct extensive unilateral and bilateral cranial defects in three clinical cases. Read More

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Maximizing the Smile Symmetry in Facial Paralysis Reconstruction: An Algorithm Based on Twenty Years' Experience.

Facial Plast Surg 2021 Jun 1;37(3):360-369. Epub 2021 Jun 1.

Department of Plastic and Reconstructive Surgery, Clínica Universidad de Navarra, Pamplona, Spain.

Over the last two decades, the senior author (B.H.) has had an extensive experience with facial paralysis reconstruction. Read More

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Prediction of pelvic mobility using whole-spinal and pelvic alignment in standing and sitting position in total hip arthroplasty patients.

J Orthop Surg (Hong Kong) 2021 May-Aug;29(2):23094990211019099

Department of Orthopedic Surgery, 13155Yokohama City University, Yokohama City, Kanagawa, Japan.

Purpose: Dislocation is a major complication after total hip arthroplasty (THA), and pelvic stiffness is reportedly a significant risk factor for dislocation. This study aimed to investigate spinopelvic alignment, and identify preoperative factors associated with postoperative pelvic mobility.

Methods: We enrolled 78 THA patients with unilateral osteoarthritis. Read More

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Clinical experience of plasmapheresis for neuromyelitis optica patients in Mexico.

Mult Scler Relat Disord 2021 Jul 15;52:103022. Epub 2021 May 15.

Multiple sclerosis and Demyelinating disorders Clinic, National Institute of Neurology and Neurosurgery, Insurgentes Sur 3877, La Fama, Tlalpan, Mexico City 14269, Mexico. Electronic address:

Background: Neuromyelitis optica spectrum disorders (NMOSDs) are a group of chronic immune-mediated demyelinating diseases of the central nervous system. Their pathophysiology dependent on humoral mediated responses caused by autoreactive IgG antibodies against aquaporin-4 water channels (AQP4-IgG) or myelin oligodendrocyte glycoprotein (MOG-IgG). Plasma exchange (PLEX) has proved to be a beneficial therapy in patients with severe relapses. Read More

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Orbital varix: A rare case of unilateral exophthalmos, case report.

Ann Med Surg (Lond) 2021 Jun 29;66:102346. Epub 2021 Apr 29.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

The etiologies of unilateral exophthalmos are multiple, rarely represented by an intra- or extra-conical vascular mass. Orbito-palpebral varixes are rare (2% of orbital masses) and represent a main cause of unilateral intermittent exophthalmos, often of an inflammatory nature. We report a Case of right orbito-palpebral varix in a 65-year-old adult, with no particular history, evolving for 2 years. Read More

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Percutaneous drainage of a fluid-containing emphysematous bulla.

BMJ Case Rep 2021 May 21;14(5). Epub 2021 May 21.

Respiratory Medicine, Homerton University Hospital NHS Foundation Trust, London, UK.

We present the case of a 38-year-old man, with congenital bullous emphysema, who presented with unilateral pleuritic chest pain, rigors and a non-productive cough. A chest X-ray on admission demonstrated extensive bilateral bullous lung disease with left-sided lung collapse. There were fluid levels present within several bullae, with the largest bulla compromising most of the posterior aspect of the left lung base. Read More

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Expanding the clinical spectrum and management of Traboulsi syndrome: report on two siblings homozygous for a novel pathogenic variant in .

Ophthalmic Genet 2021 Aug 21;42(4):493-499. Epub 2021 May 21.

Department of Ophthalmology, Ghent University Hospital, Ghent, Belgium.

Background: Traboulsi syndrome is a very rare, syndromic form of ectopia lentis that is potentially sight-threatening at a young age. It is characterized by typical facial, skeletal and ocular signs.

Materials And Methods: Two siblings, born to consanguineous parents, with a clinical phenotype consistent with Traboulsi syndrome, underwent extensive ophthalmic imaging and exome-based genetic testing. Read More

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Outcomes of vitrectomy for retinal detachment in a patient with Ehlers-Danlos syndrome type IV: a case report.

J Med Case Rep 2021 May 20;15(1):249. Epub 2021 May 20.

Eye Hospital, University Medical Centre Ljubljana, Grablovičeva ulica 46, 1000, Ljubljana, Slovenia.

Background: The Ehlers-Danlos syndrome (EDS) is a group of connective tissue disorders characterized by fragile blood vessels and an increased tendency for bleeding and scarring. Here, we report the outcome of a pars plana vitrectomy for the treatment of rhegmatogenous retinal detachment in a patient with EDS type IV (vascular type).

Case Presentation: A 40-year-old Slovenian man with high myopia, unilateral bullous retinal detachment, and vitreous hemorrhage was referred for surgery. Read More

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Catastrophic, Bilateral Retinal Vascular Occlusion after Intravitreal Bevacizumab Injection.

Retin Cases Brief Rep 2021 May 10. Epub 2021 May 10.

West Coast Retina Medical Group, San Francisco, California. The Department of Ophthalmology, California Pacific Medical Center, San Francisco, California. Massachusetts Eye and Ear Infirmary, Harvard Medical School, Ocular Immunology and Uveitis Service, Boston, Massachusetts. The Department of Ophthalmology, Stanford University School of Medicine, Stanford, California. The Francis I. Proctor Foundation, UCSF School of Medicine, San Francisco, California. Massachusetts Eye and Ear Infirmary, Harvard Medical School, Vitreoretinal Service, Boston, Massachusetts. Ophthalmic Consultants of Boston, Vitreoretinal Service, Boston, Massachusetts. Ophthalmic Consultants of Boston, Uveitis Service, Boston, Massachusetts.

Purpose: To describe two cases of catastrophic, bilateral retinal vascular occlusion following intravitreal (IVT) bevacizumab injection.

Methods: Case series. Main outcome measures included clinical and fluorescein angiography (FA) findings. Read More

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Occurrence and Risk Factors of Infected Pancreatic Necrosis in Intensive Care Unit-Treated Patients with Necrotizing Severe Acute Pancreatitis.

J Gastrointest Surg 2021 May 13. Epub 2021 May 13.

Department of Abdominal Surgery, University of Helsinki and Helsinki University Hospital, P.O. BOX 340, 00029 HUS, Helsinki, Finland.

Background: In patients with severe acute pancreatitis (SAP), infected pancreatic necrosis (IPN) is associated with a worsened outcome. We studied risk factors and consequences of IPN in patients with necrotizing SAP.

Methods: The study consisted of a retrospective cohort of 163 consecutive patients treated for necrotizing SAP at a university hospital intensive care unit (ICU) between 2010 and 2018. Read More

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Unilateral frosted branch angiitis in an human immunodeficiency virus-infected patient with concurrent COVID-19 infection: a case report.

J Med Case Rep 2021 May 12;15(1):267. Epub 2021 May 12.

Department of Ophthalmology, Queen Elizabeth Hospital, Sabah, Malaysia.

Background: Frosted branch angiitis (FBA) is an uncommon ocular sign with multiple causes. With the recent outbreak of coronavirus disease 2019 (COVID-19), many cases of ocular manifestation in association with this disease have been reported. However, as yet we have no complete understanding of this condition. Read More

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Case Report: Atraumatic Orbital Emphysema after Bronchoscopy with Endobronchial Biopsy.

Optom Vis Sci 2021 05;98(5):440-445

Significance: Orbital emphysema is a well-documented condition where air enters the orbital soft tissue typically because of direct or indirect trauma; however, atraumatic cases can be encountered. The following is a novel case report of acute unilateral atraumatic orbital emphysema 24 hours after bronchoscopy with endobronchial biopsy.

Purpose: To the best of the authors' knowledge, this is the first known case report of atraumatic orbital emphysema as a postprocedure complication of bronchoscopy with endobronchial biopsy in the literature. Read More

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Dyspnea With Unilateral Pulmonary Ground Glass Opacities and Cavitary Lesions.

Chest 2021 May;159(5):e337-e342

Section Pulmonary and Critical Care, St. Luke's University Health Network, Bethlehem, PA.

Case Presentation: A 62-year-old man presented with a 3-month history of shortness of breath and a dry cough. He had a medical history of hypertension (without use of angiotensin-converting enzyme inhibitors), hyperlipidemia, depression, and 10-pack-years of cigarette smoking several decades ago. He was a limousine driver and denied any history of occupational high-risk exposures. Read More

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Renal tubular dilation and fibrosis after unilateral ureter obstruction revealed by relaxometry and spin-lock exchange MRI.

NMR Biomed 2021 Aug 8;34(8):e4539. Epub 2021 May 8.

Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

We evaluated the use of quantitative MRI relaxometry, including the dispersion of spin-lock relaxation with different locking fields, for detecting and assessing tubular dilation and fibrosis in a mouse model of unilateral ureter obstruction (UUO). C57BL/6 J and BALB/c mice that exhibit different levels of tubular dilation and renal fibrosis after UUO were subjected to MR imaging at 7 T. Mice were imaged before UUO surgery, and at 5, 10 and 15 days after surgery. Read More

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