119,088 results match your criteria exercise condition

The Experimental Effect of Parent Versus Peer Influence on Children's Physical Activity and Sedentary Behavior.

Pediatr Exerc Sci 2021 Jun 24:1-7. Epub 2021 Jun 24.

Kent State University.

Purpose: To assess children's physical activity, sedentary behavior, liking, and motivation during 3 separate simulated recess conditions: playing alone, with their parent participating, and with their peer participating.

Methods: Children participated in the 3 separate conditions. During each condition, the children had access to an outdoor playground and sedentary activity options for 30 minutes. Read More

View Article and Full-Text PDF

Progressive Visual Occlusion and Postural Control Responses in Individuals With and Without Chronic Ankle Instability.

J Sport Rehabil 2021 Jun 24:1-6. Epub 2021 Jun 24.

Context: Prophylactic and rehabilitative balance training is needed to maximize postural control and develop appropriate sensory organization strategies. Partially occluding vision during functional exercise may promote appropriate sensory organization strategies, but little is known about the influence of partially occluded vision on postural control in those with and without a history of musculoskeletal injury.

Objective: To determine the effect of increasing levels of visual occlusion on postural control in a heterogeneous sample of those with and without chronic ankle instability (CAI). Read More

View Article and Full-Text PDF

Inflammatory and oxidative biomarkers as determinants of functional capacity in patients with COPD assessed by 6-min walk test-derived outcomes.

Exp Gerontol 2021 Jun 21:111456. Epub 2021 Jun 21.

Laboratório de Inflamação e Metabolismo - LIM - CIPq/Saúde, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Minas Gerais, Brazil; Programa de Pós-Graduação Multicêntrico em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Minas Gerais, Brazil. Electronic address:

Introduction: Reduction in functional capacity is a negative clinical outcome of chronic obstructive pulmonary disease (COPD). Studies have shown association between inflammatory and oxidative stress biomarkers and functional capacity. However, it is unclear whether these biomarkers are associated with outcomes of functional capacity. Read More

View Article and Full-Text PDF

Schistosomal appendicitis: Case series and systematic literature review.

PLoS Negl Trop Dis 2021 Jun 24;15(6):e0009478. Epub 2021 Jun 24.

The Cambridge Centre for Sport & Exercise Sciences, Anglia Ruskin University, Cambridge, United Kingdom.

Background: Globally, schistosomiasis affects at least 240 million people each year with a high proportion of cases in sub-Saharan Africa. The infection presents a wide range of symptoms mainly at the gastrointestinal and urogenital level. Cases of schistosomiasis-related appendicitis are seldom reported. Read More

View Article and Full-Text PDF

Towards Molecular Therapy of Atrioventricular Nodal Dysfunction.

Circ Res 2021 Jun 24;129(1):6-8. Epub 2021 Jun 24.

Amsterdam University Medical Centers, the Netherlands.

View Article and Full-Text PDF

Physical activity, sports participation and exercise-related constraints in adult women with primary hypothyroidism treated with thyroid hormone replacement therapy.

J Sports Sci 2021 Jun 24:1-10. Epub 2021 Jun 24.

Department of Rehabilitation, Physical Therapy Science and Sport, University Medical Center Utrecht, Utrecht, The Netherlands.

Awareness of physical activity (PA) constraints in patients with primary hypothyroidism on thyroid hormone replacement therapy (THR) is important. Hence, this cross-sectional matched case-control study aimed to determine PA and sports participation (SP) in patients with hypothyroidism on THR in comparison to control subjects. Accordingly, survey questions were selected from the National Survey on Injuries and Physical Activity in the Netherlands (IPAN), supplemented with questions related to self-reported clinical characteristics and exercise-related constraints (ERC) of patients. Read More

View Article and Full-Text PDF

Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice.

Mol Neurobiol 2021 Jun 23. Epub 2021 Jun 23.

Department of Rehabilitation Sciences, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, 11 Yuk Choi Road, Hung Hom, Hong Kong SAR.

Administration of exercise mimetic drugs could be a novel therapeutic approach to combat comorbid neurodegeneration and metabolic syndromes. Adiponectin is an adipocyte-secreted hormone. In addition to its antidiabetic effect, adiponectin mediates the antidepressant effect of physical exercise associated with adult hippocampal neurogenesis. Read More

View Article and Full-Text PDF

COVID-19 Patient Returned to Work after Long Hospitalization and Follow-up: A Case Report.

Prog Rehabil Med 2021 8;6:20210025. Epub 2021 Jun 8.

Department of Rehabilitation Medicine, Hyogo College of Medicine, Nishinomiya, Japan.

Background: Coronavirus disease 2019 (COVID-19) causes severe respiratory dysfunction and post-intensive care syndrome (PICS), which can significantly affect the return to work after discharge from the hospital. This report describes the first case of a patient with severe COVID-19 at our institution during the first wave of the COVID-19 pandemic (February to June 2020) who returned to work following rehabilitation management.

Case: A 48-year-old female nurse was admitted with COVID-19 and underwent mechanical ventilation (MV). Read More

View Article and Full-Text PDF

Managing cardiovascular disease risk in South Asian kidney transplant recipients.

World J Transplant 2021 Jun;11(6):147-160

Kidney Transplant Program, St. Michael's Hospital, Toronto M5C 2T2, ON, Canada.

South Asians (SA) are at higher cardiovascular risk than other ethnic groups, and SA kidney transplant recipients (SA KTR) are no exception. SA KTR experience increased major adverse cardiovascular events both early and late post-transplantation. Cardiovascular risk management should therefore begin well before transplantation. Read More

View Article and Full-Text PDF

The burden of excessive saturated fatty acid intake attributed to ultra-processed food consumption: a study conducted with nationally representative cross-sectional studies from eight countries.

J Nutr Sci 2021 4;10:e43. Epub 2021 Jun 4.

Department of Nutrition, School of Public Health, University of São Paulo, São Paulo, Brazil.

Cross-sectional nutritional survey data collected in eight countries were used to estimate saturated fatty acid intakes. Our objective was to estimate the proportion of excessive saturated fatty acid intakes (>10 % of total energy intake) that could be avoided if ultra-processed food consumption was reduced to levels observed in the first quintile of each country. Secondary analysis was performed of 24 h dietary recall or food diary/record data collected by the most recently available nationally representative cross-sectional surveys carried out in Brazil (2008-9), Chile (2010), Colombia (2005), Mexico (2012), Australia (2011-12), the UK (2008-16), Canada (2015) and the US (2015-16). Read More

View Article and Full-Text PDF

Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy.

Chem Sci 2021 Apr 29;12(21):7308-7323. Epub 2021 Apr 29.

Department of Biomedical Sciences, Florida State University, College of Medicine 1115 West Call Street, Room: 1370 (lab) - 1350-H (office) Tallahassee FL 32306 USA +1-850-645-0016.

Cardiac TnC (cTnC) is highly conserved among mammals, and genetic variants can result in disease by perturbing Ca-regulation of myocardial contraction. Here, we report the molecular basis of a human mutation in cTnC's αD-helix (-p.C84Y) that impacts conformational dynamics of the D/E central-linker and sampling of discrete states in the N-domain, favoring the "primed" state associated with Ca binding. Read More

View Article and Full-Text PDF

Effect of Oxidative Stress on Diaphragm Dysfunction and Exercise Intervention in Chronic Obstructive Pulmonary Disease.

Front Physiol 2021 7;12:684453. Epub 2021 Jun 7.

Department of Sports Medicine, Shanghai University of Sport, Shanghai, China.

Chronic obstructive pulmonary disease (COPD) can cause extrapulmonary injury such as diaphragm dysfunction. Oxidative stress is one of the main factors causing diaphragm dysfunction in COPD. Exercise plays a positive role in the prevention and treatment of diaphragm dysfunction in COPD, and the changes in diaphragm structure and function induced by exercise are closely related to the regulation of oxidative stress. Read More

View Article and Full-Text PDF

Physical Activity and Inhibition of ACE Additively Modulate ACE/ACE-2 Balance in Heart Failure in Mice.

Front Pharmacol 2021 7;12:682432. Epub 2021 Jun 7.

Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.

Angiotensin-converting enzyme inhibition (ACE-I) and physical activity favorably modulate the ACE/ACE-2 balance. However, it is not clear whether physical activity and ACE-I could synergistically modulate ACE/ACE-2 balance in the course of heart failure (HF). Here, we studied the effects of combined spontaneous physical activity and ACE-I-based treatment on angiotensin (Ang) pattern and cardiac function in a mouse model of HF (Tgαq*44). Read More

View Article and Full-Text PDF

Bioinformatics Analysis Identifies Potential Ferroptosis Key Genes in the Pathogenesis of Intracerebral Hemorrhage.

Front Neurosci 2021 7;15:661663. Epub 2021 Jun 7.

Department of Rehabilitation Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.

Intracerebral hemorrhage (ICH) is a dangerous neurological disease. The mechanism of ferroptosis in ICH remains unclear. Using bioinformatics analysis, we aimed to identify the key molecules involved in ferroptosis and provide treatment targets for ICH to further explore the mechanism of ferroptosis in ICH. Read More

View Article and Full-Text PDF

Diabetes and COVID19: a bidirectional relationship.

Eur J Clin Nutr 2021 Jun 23. Epub 2021 Jun 23.

Fortis-C-DOC Centre of Excellence for Diabetes, Metabolic Diseases and Endocrinology, New Delhi, India.

The advent and rapid spread of the coronavirus disease-2019 (COVID19) pandemic across the world has focused attention on the relationship of commonly occurring comorbidities such as diabetes on the course and outcomes of this infection. While diabetes does not seem to be associated with an increased risk of COVID19 infection per se, it has been clearly demonstrated that the presence of hyperglycemia of any degree predisposes to worse outcomes, such as more severe respiratory involvement, ICU admissions, need for mechanical ventilation and mortality. Further, COVID19 infection has been associated with the development of new-onset hyperglycemia and diabetes, and worsening of glycemic control in pre-existing diabetes, due to direct pancreatic damage by the virus, body's stress response to infection (including cytokine storm) and use of diabetogenic drugs such as corticosteroids in the treatment of severe COVID19. Read More

View Article and Full-Text PDF

Association between serum sphingolipids and eudaimonic well-being in white U.S. adults.

Sci Rep 2021 Jun 23;11(1):13139. Epub 2021 Jun 23.

Institute on Aging, University of Wisconsin-Madison, Madison, WI, USA.

Emerging research has linked psychological well-being with many physiological markers as well as morbidity and mortality. In this analysis, the relationship between components of eudaimonic well-being and serum sphingolipids levels was investigated using data from a large national survey of middle-aged American adults (Midlife in the United States). Health behaviors (i. Read More

View Article and Full-Text PDF

Quantifying prescribed high dose opioids in the community and risk of overdose.

BMC Public Health 2021 Jun 24;21(1):1174. Epub 2021 Jun 24.

Salvation Army Centre for Addiction Services and Research, Faculty of Social Sciences, Colin Bell Building, University of Stirling, Stirling, FK9 4LA, Scotland.

Background: Opioid prescribing for a range of health issues is increasing globally. The risk of fatal and non-fatal overdose is increased among people prescribed strong opioids: in high doses in the context of polypharmacy (the use of multiple medications at the same time), especially with other sedatives; and among people with multiple morbidities including cardiorespiratory, hepatic and renal conditions. This study described and quantified the prescribing of strong opioids, comorbidities and other overdose risk factors among those prescribed strong opioids, and factors associated with high/very high opioid dosage in a regional health authority in Scotland as part of a wider service improvement exercise. Read More

View Article and Full-Text PDF

The association of physical activity on homocysteine in pregnant women.

J Matern Fetal Neonatal Med 2021 Jun 23:1-8. Epub 2021 Jun 23.

Department of Human Movement Sciences, Old Dominion University, Norfolk, VA, USA.

Introduction: Women with high levels of physical activity have improved pregnancy, labor, and delivery outcomes related to cardiovascular health. Hyperhomocysteinemia, which predicts cardiovascular disease risk, is associated with maternal vascular complications during pregnancy, such as placental abruption and preeclampsia. However, studies are lacking on whether physical activity impacts homocysteine in pregnant women, pointing to a potential mechanism behind the improved cardiovascular health in women who exercise during pregnancy. Read More

View Article and Full-Text PDF

Body mass-normalized moderate dose of dietary nitrate intake improves endothelial function and walking capacity in patients with peripheral artery disease.

Am J Physiol Regul Integr Comp Physiol 2021 06 23. Epub 2021 Jun 23.

School of Health & Kinesiology, University of Nebraska at Omaha, Omaha, NE, United States.

Peripheral artery disease (PAD) is characterized by the accumulation of atherosclerotic plaques in the lower extremity conduit arteries, which impairs blood flow and walking capacity. Dietary nitrate has been used to reduce blood pressure (BP) and improve walking capacity in PAD. However, a standardized dose for PAD has not been determined. Read More

View Article and Full-Text PDF

Occupational heat exposure and the risk of chronic kidney disease of non-traditional origin in the United States.

Am J Physiol Regul Integr Comp Physiol 2021 06 23. Epub 2021 Jun 23.

Department of Kinesiology, School of Public Health, Indiana University, Bloomington, IN, United States.

Occupational heat exposure is linked to the development of kidney injury and disease in individuals who frequently perform physically demanding work in the heat. For instance, in Central America, an epidemic of chronic kidney disease of non-traditional origin (CKDnt) is occurring among manual laborers, while potentially related epidemics have emerged in India and Sri Lanka. There is growing concern that workers in the United States suffer with CKDnt, but reports are limited. Read More

View Article and Full-Text PDF

A randomized trial of exercise and diet on health-related quality of life in survivors of breast cancer with overweight or obesity.

Cancer 2021 Jun 23. Epub 2021 Jun 23.

Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania.

Background: Obesity is a chronic, relapsing, and progressive disease; it is associated with poor health-related quality of life (HRQOL) in survivors of breast cancer.

Methods: In this 2 × 2 factorial trial, 351 survivors of breast cancer with overweight or obesity were randomized to 1 of 4 treatment groups for 52 weeks: control, exercise alone, diet alone, or exercise plus diet. HRQOL end points were measured at baseline and at week 52 using the 36-Item Medical Outcomes Survey-Short Form (SF-36). Read More

View Article and Full-Text PDF

Physical exercise is effective for neuropsychiatric symptoms in Alzheimer's disease: a systematic review.

Arq Neuropsiquiatr 2021 May;79(5):447-456

Universidade Federal do Triângulo Mineiro, Programa de Pós-Graduação em Educação Física, Uberaba MG, Brazil.

Background: Neuropsychiatric symptoms are disorders frequently seen in Alzheimer's disease. These symptoms contribute to reduction of brain reserve capacity and, in addition, they present unfavorable implications, such as: poor prognosis for the disease, increased functional decline, increased burden on the caregiver and institutionalization. This scenario makes neuropsychiatric symptoms one of the biggest problems in Alzheimer's disease, and gives rise to a need for treatments focused on improving these symptoms. Read More

View Article and Full-Text PDF

Limited cardiopulmonary capacity in patients with liver cirrhosis when compared to healthy subjects.

Rev Assoc Med Bras (1992) 2021 Jan;67(1):94-100

Universidade Federal do Rio de Janeiro, Escola de Educação Física e Desportos - Rio de Janeiro (RJ), Brasil.

Objectives: The present study compared cardiorespiratory capacity between cirrhotic patients and healthy subjects.

Methods: Nineteen cirrhotic patients and 19 healthy subjects, paired by age and gender, participated in the study. Volunteers performed an incremental cardiopulmonary test with a ramp protocol, a ventilatory and metabolic variables were obtained and analyzed. Read More

View Article and Full-Text PDF
January 2021

The human gut microbiome and health inequities.

Proc Natl Acad Sci U S A 2021 Jun;118(25)

Department of Anthropology, Northwestern University, Evanston, IL 60208.

Individuals who are minoritized as a result of race, sexual identity, gender, or socioeconomic status experience a higher prevalence of many diseases. Understanding the biological processes that cause and maintain these socially driven health inequities is essential for addressing them. The gut microbiome is strongly shaped by host environments and affects host metabolic, immune, and neuroendocrine functions, making it an important pathway by which differences in experiences caused by social, political, and economic forces could contribute to health inequities. Read More

View Article and Full-Text PDF

Utilization and Impact of Complementary and Alternative Medicines in Symptomatic Autoimmune Hepatitis Patients.

Dig Dis Sci 2021 Jun 23. Epub 2021 Jun 23.

Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, 702 Rotary Circle, Suite 225, Indianapolis, IN, 46202, USA.

Background: Complementary and alternative medicine (CAM) use has become increasingly common. It is also prevalent in patients with chronic liver disease, but the scope, depth, and safety of use is not well known.

Aims: This study aimed to evaluate the prevalence and patterns of CAM use in autoimmune hepatitis (AIH) patients. Read More

View Article and Full-Text PDF


Harefuah 2021 Jun;160(6):377-381

Child Health and Sports Center, Meir Medical Center.

Introduction: McArdle disease (Glycogen storage disease type V) is a myopathy caused by an inherited deficit of muscle glycogen phosphorylase (PYGM). Since glycogen is an important fuel for muscular activity, people with McArdle's disease experience exercise intolerance. Dynamic or static vigorous exercise may lead to rhabdomyolysis, myoglobinuria and renal failure. Read More

View Article and Full-Text PDF

Frailty in elderly inpatients with cardiovascular disease: an exploration of associated factors.

Eur J Cardiovasc Nurs 2021 Jun 23. Epub 2021 Jun 23.

School of Nursing, Medical College, Soochow University, Box 203, No.1, Shizi St., Suzhou, 215000, Jiangsu, China.

Aims: Older patients with cardiovascular diseases (CVDs) are more likely to develop frailty. Few studies have investigated frailty status, and its multiple associated factors, in this population. The aim of the present study was to explore frailty status, and its multidimensional associated factors, in elderly inpatients with CVDs. Read More

View Article and Full-Text PDF

Comparative Lipidomics of Chick Yolk Sac during the Embryogenesis Provides Insight into Understanding the Development-Related Lipid Supply.

J Agric Food Chem 2021 Jun 23. Epub 2021 Jun 23.

CASS Food Research Centre, School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria 3125, Australia.

Yolk sac (YS, include the yolk content) at different chick embryogenesis stages possesses varying lipid distributions, which are nutrition-influencing factors for the health of an early embryo and a later adult. YS lipids can substantially influence embryogenesis metabolism, but a comprehensive understanding of lipid's influence remains unknown. Herein, the effects of embryogenesis on lipid profiling of chick YS were investigated by UHPLC-MS/MS-based lipidomics. Read More

View Article and Full-Text PDF

Differences in adolescent cerebral perfusion as a function of obesity: Results from the FLEX-Brain study.

Obesity (Silver Spring) 2021 Jul;29(7):1171-1177

Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Objective: Children and adolescents have greater resting cerebral blood flow (rCBF) during periods of rapid brain growth. Overweight and obesity have a global impact on brain cerebrovascular health in adults, but whether these effects are discernable in adolescents with overweight and obesity remains unknown. This study examined differences in rCBF between adolescents with a healthy weight (HW) and adolescents with overweight or obesity (OW). Read More

View Article and Full-Text PDF

Hearing impairment and diverse health outcomes : An umbrella review of meta-analyses of observational studies.

Wien Klin Wochenschr 2021 Jun 22. Epub 2021 Jun 22.

Vision and Eye Research Institute (VERI), School of Medicine, Anglia Ruskin University, Young Street, CB1 2LZ, Cambridge, UK.

Background: Globally, it is estimated that approximately 1.3 billion people live with some form of hearing impairment. Major causes of hearing loss include infection/disease, age-related factors, and occupational factors. Read More

View Article and Full-Text PDF