2,176 results match your criteria evidence arctic


Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke.

Cochrane Database Syst Rev 2021 Dec 1;12:CD010995. Epub 2021 Dec 1.

Brain and Circulation Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

Background: About one in five strokes occur during sleep (wake-up stroke). People with wake-up strokes have previously been considered to be ineligible for thrombolytic treatment because the time of stroke onset is unknown. However, recent studies suggest benefit from recanalisation therapies in selected patients. Read More

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December 2021

The effect of azithromycin for management of HIV-associated chronic lung disease on right heart function: Results from the BREATHE trial.

Int J Cardiol Heart Vasc 2021 Dec 20;37:100920. Epub 2021 Nov 20.

Biomedical Research & Training Institute, Harare, Zimbabwe.

Background: Right heart abnormalities and pulmonary hypertension (PH) may be secondary to chronic lung disease. Chronic lung disease is common in children with HIV. In the BREATHE trial ( NCT02426112), azithromycin (AZM) reduced the risk of acute respiratory exacerbations in children aged 6-19 years with HIV-associated chronic lung disease (HCLD) taking antiretroviral therapy. Read More

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December 2021

New climate models reveal faster and larger increases in Arctic precipitation than previously projected.

Nat Commun 2021 Nov 30;12(1):6765. Epub 2021 Nov 30.

College of Engineering, Maths, and Physical Sciences, University of Exeter, Exeter, UK.

As the Arctic continues to warm faster than the rest of the planet, evidence mounts that the region is experiencing unprecedented environmental change. The hydrological cycle is projected to intensify throughout the twenty-first century, with increased evaporation from expanding open water areas and more precipitation. The latest projections from the sixth phase of the Coupled Model Intercomparison Project (CMIP6) point to more rapid Arctic warming and sea-ice loss by the year 2100 than in previous projections, and consequently, larger and faster changes in the hydrological cycle. Read More

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November 2021

sp. nov., isolated from Arctic tundra soil, and emended descriptions of , and .

Int J Syst Evol Microbiol 2021 Nov;71(11)

China Center for Type Culture Collection (CCTCC), College of Life Sciences, Wuhan University, Wuhan 430072, PR China.

Strain Q3-56, isolated from Arctic tundra soil, was found to be a Gram-stain-negative, yellow-pigmented, oxidase- and catalase-positive, non-motile, non-spore-forming, rod-shaped and aerobic bacterium. Strain Q3-56 grew optimally at pH 7.0 and 28 °C. Read More

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November 2021

Can a key boreal Calanus copepod species now complete its life-cycle in the Arctic? Evidence and implications for Arctic food-webs.

Ambio 2021 Nov 29. Epub 2021 Nov 29.

The Laboratory, Citadel Hill, Plymouth, PL1 2PB, UK.

The changing Arctic environment is affecting zooplankton that support its abundant wildlife. We examined how these changes are influencing a key zooplankton species, Calanus finmarchicus, principally found in the North Atlantic but expatriated to the Arctic. Close to the ice-edge in the Fram Strait, we identified areas that, since the 1980s, are increasingly favourable to C. Read More

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November 2021

Insight and the number of completed modules predict a reduction of positive symptoms in an Internet-based intervention for people with psychosis.

Psychiatry Res 2021 Dec 25;306:114223. Epub 2021 Sep 25.

Department of Psychology, MSH Medical School Hamburg, Hamburg, Germany. Electronic address:

Emerging evidence suggests that Internet-based interventions for people with psychosis (ICBTp) are feasible and efficacious. However, predictors of adherence and treatment outcomes are largely unknown. To narrow this research gap, we conducted secondary analyses on data from a randomized controlled trial, which evaluated an eight-week ICBTp intervention targeting topics, such as voice hearing, mindfulness, and others. Read More

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December 2021

North Atlantic minke whale () feeding habits and migrations evaluated by stable isotope analysis of baleen.

Ecol Evol 2021 Nov 24;11(22):16344-16353. Epub 2021 Oct 24.

St. Catharine's College Cambridge UK.

Isotopic analyses of the incrementally growing baleen in Mysticeti have been used to learn about their feeding and movement patterns. Using methods previously applied to Pacific minke whales, stable δN and δC isotope values were measured along the baleen plates of male and female minke whales from two locations in the Northeast Atlantic. The sample sizes used in this study are comparable to those previously used in the literature, and, although limited in size, the evidence suggests differences in isotopic signatures between whales caught at different locations. Read More

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November 2021

Effect of azithromycin on incidence of acute respiratory exacerbations in children with HIV taking antiretroviral therapy and co-morbid chronic lung disease: a secondary analysis of the BREATHE trial.

EClinicalMedicine 2021 Dec 13;42:101195. Epub 2021 Nov 13.

MRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.

Background: In the BREATHE trial weekly azithromycin decreased the rate of acute respiratory exacerbations (AREs) compared to placebo among children and adolescents with HIV-associated chronic lung disease (CLD) taking antiretroviral therapy (ART). The aim of this analysis was to identify risk factors associated with AREs and mediators of the effect of azithromycin on AREs.

Methods: The primary outcome of this analysis was the rate of AREs by study arm up to 49 weeks. Read More

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December 2021

Evidence of Arctic Fox Survival following Exposure to Rabies Virus.

J Wildl Dis 2021 Nov 23. Epub 2021 Nov 23.

US Department of Agriculture, National Wildlife Research Center, 4101 Laporte Avenue, Fort Collins, Colorado 80521, USA.

The arctic fox variant of the rabies virus (RABV) is enzootic in the circumpolar north. Reports of abortive RABV exposures motivated a retrospective analysis of sera from 41 arctic foxes captured at Karrak Lake in Nunavut, Canada, during 2011-2015. Estimated RABV antibody prevalence among foxes was 14% (95% confidence interval, 7-28%). Read More

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November 2021

Endogenous Circulating Sex Hormone Concentrations and Colon Cancer Risk in Postmenopausal Women: A Prospective Study and Meta-Analysis.

JNCI Cancer Spectr 2021 Dec 28;5(6):pkab084. Epub 2021 Sep 28.

Faculty of Health Sciences, Department of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

Background: Observational studies have consistently reported that postmenopausal hormone therapy use is associated with lower colon cancer risk, but epidemiologic studies examining the associations between circulating concentrations of endogenous estrogens and colorectal cancer have reported inconsistent results.

Methods: We investigated the associations between circulating concentrations of estrone, estradiol, free estradiol, testosterone, free testosterone, androstenedione, dehydroepiandrosterone (DHEA), progesterone, and sex hormone-binding globulin (SHBG) with colon cancer risk in a nested case-control study of 1028 postmenopausal European women (512 colon cancer cases, 516 matched controls) who were noncurrent users of exogenous hormones at blood collection. Multivariable conditional logistic regression models were used to compute odds ratios and 95% confidence intervals to evaluate the association between circulating sex hormones and colon cancer risk. Read More

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December 2021

Organisation of services and systems of care in paediatric spinal cord injury rehabilitation in seven countries: a survey with a descriptive cross-sectional design.

Spinal Cord 2021 Nov 20. Epub 2021 Nov 20.

The Research Department, Sunnaas Rehabilitation Hospital, Bjørnemyr, Norway.

Study Design: International multicentre cross-sectional study.

Objectives: To describe the organisation and systems of paediatric spinal cord injury (SCI) rehabilitation services in seven countries and compare them with available recommendations and key features of paediatric SCI.

Setting: Ten SCI rehabilitation units in seven countries admitting children and adolescents with SCI < 18 years of age. Read More

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November 2021

Dietary Fatty Acids, Macronutrient Substitutions, Food Sources and Incidence of Coronary Heart Disease: Findings From the EPIC-CVD Case-Cohort Study Across Nine European Countries.

J Am Heart Assoc 2021 Nov 19:e019814. Epub 2021 Nov 19.

Danish Cancer Society Research Center Copenhagen Denmark.

Background There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain. Methods and Results We conducted a case-cohort study involving 10 529 incident CHD cases and a random subcohort of 16 730 adults selected from a cohort of 385 747 participants in 9 countries of the EPIC (European Prospective Investigation into Cancer and Nutrition) study. Read More

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November 2021

MapToCleave: High-throughput profiling of microRNA biogenesis in living cells.

Cell Rep 2021 Nov;37(7):110015

Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden. Electronic address:

Previous large-scale studies have uncovered many features that determine the processing of microRNA (miRNA) precursors; however, they have been conducted in vitro. Here, we introduce MapToCleave, a method to simultaneously profile processing of thousands of distinct RNA structures in living cells. We find that miRNA precursors with a stable lower basal stem are more efficiently processed and also have higher expression in vivo in tissues from 20 animal species. Read More

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November 2021

Neolithic farmers or Neolithic foragers? Organic residue analysis of early pottery from Rakushechny Yar on the Lower Don (Russia).

Archaeol Anthropol Sci 2021 26;13(8):141. Epub 2021 Jul 26.

BioArCh, University of York, Environment Building, Wentworth Way Heslington, York, YO10 5DD UK.

The emergence of pottery in Europe is associated with two distinct traditions: hunter-gatherers in the east of the continent during the early 6th millennium BC and early agricultural communities in the south-west in the late 7th millennium BC. Here we investigate the function of pottery from the site of Rakushechny Yar, located at the Southern fringe of Eastern Europe, in this putative contact zone between these two economic 'worlds'. To investigate, organic residue analysis was conducted on 120 samples from the Early Neolithic phase (ca. Read More

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Recurrent transitions to Little Ice Age-like climatic regimes over the Holocene.

Clim Dyn 2021 6;56(11-12):3817-3833. Epub 2021 Feb 6.

Laboratory of Chronology, Finnish Museum of Natural History, University of Helsinki, Gustaf Hällströmin Katu 2, 00014 Helsinki, Finland.

Holocene climate variability is punctuated by episodic climatic events such as the Little Ice Age (LIA) predating the industrial-era warming. Their dating and forcing mechanisms have however remained controversial. Even more crucially, it is uncertain whether earlier events represent climatic regimes similar to the LIA. Read More

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February 2021

Prenatal exposure to persistent organic pollutants and metals and problematic child behavior at 3-5 years of age: a Greenlandic cohort study.

Sci Rep 2021 Nov 12;11(1):22182. Epub 2021 Nov 12.

Center for Arctic Health and Molecular Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark.

High levels of persistent organic pollutants (POPs) and heavy metals are found in Arctic populations. POP and heavy metals are linked to impaired cognitive development. This study examined associations between prenatal POP and metals exposure and problematic child behavior using the Strength and Difficulties Questionnaire (SDQ). Read More

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November 2021

Mitochondrial genomes of two parasitic Cuscuta species lack clear evidence of horizontal gene transfer and retain unusually fragmented ccmF genes.

BMC Genomics 2021 Nov 12;22(1):816. Epub 2021 Nov 12.

Department of Ecology, Environment and Plant Sciences, Stockholm University, SE-106 91, Stockholm, Sweden.

Background: The intimate association between parasitic plants and their hosts favours the exchange of genetic material, potentially leading to horizontal gene transfer (HGT) between plants. With the recent publication of several parasitic plant nuclear genomes, there has been considerable focus on such non-sexual exchange of genes. To enhance the picture on HGT events in a widely distributed parasitic genus, Cuscuta (dodders), we assembled and analyzed the organellar genomes of two recently sequenced species, C. Read More

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November 2021

Modeling Eastern Russian High Arctic Geese (Anser fabalis, A. albifrons) during moult and brood rearing in the 'New Digital Arctic'.

Sci Rep 2021 Nov 11;11(1):22051. Epub 2021 Nov 11.

EWHALE lab - Institute of Arctic Biology, Biology & Wildlife Department, University of Alaska Fairbanks (UAF), Fairbanks, Alaska, USA.

Many polar species and habitats are now affected by man-made global climate change and underlying infrastructure. These anthropogenic forces have resulted in clear implications and many significant changes in the arctic, leading to the emergence of new climate, habitats and other issues including digital online infrastructure representing a 'New Artic'. Arctic grazers, like Eastern Russian migratory populations of Tundra Bean Goose Anser fabalis and Greater White-fronted Goose A. Read More

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November 2021

Effects of competitive pressure and habitat heterogeneity on niche partitioning between Arctic and boreal congeners.

Sci Rep 2021 Nov 11;11(1):22133. Epub 2021 Nov 11.

British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge, CB3 0ET, UK.

The rapidly changing climate in the Arctic is expected to have a major impact on the foraging ecology of seabirds, owing to changes in the distribution and abundance of their prey but also that of competitors (e.g. southerly species expanding their range into the Arctic). Read More

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November 2021

Parenting interventions for families with refugee backgrounds: a randomized factorial, mixed-methods design study protocol.

Trials 2021 Nov 11;22(1):790. Epub 2021 Nov 11.

UiT The Arctic University of Norway, Tromsø, Norway.

Background: Raising children in new social and cultural contexts can be challenging for parents. In order to help parents address these challenges, the Norwegian government has instituted a policy of mandatory parent training for families who settle in Norway as refugees. The Incredible Years (IY) and The International Child Development Programme (ICDP) have been widely adopted throughout Norway. Read More

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November 2021

Effectiveness of Natalizumab in Achieving No Evidence of Disease Activity (NEDA-3)-Data From a Local Norwegian Cohort.

Front Neurol 2021 20;12:765837. Epub 2021 Oct 20.

Department of Neurology, Nordland Hospital Trust, Bodø, Norway.

We aimed to determine the effectiveness of natalizumab (NTZ) by assessing overall No Evidence of Disease Activity 3 (NEDA-3) in a local Norwegian cohort. NTZ is an immunomodulating drug used in the treatment of multiple sclerosis (MS). It has typically been used as a second-line treatment, but certain patients with high disease activity have started directly with NTZ. Read More

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October 2021

Process-explicit models reveal pathway to extinction for woolly mammoth using pattern-oriented validation.

Ecol Lett 2021 Nov 5. Epub 2021 Nov 5.

Center for Macroecology, Evolution, and Climate, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.

Pathways to extinction start long before the death of the last individual. However, causes of early stage population declines and the susceptibility of small residual populations to extirpation are typically studied in isolation. Using validated process-explicit models, we disentangle the ecological mechanisms and threats that were integral in the initial decline and later extinction of the woolly mammoth. Read More

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November 2021

Multiple energy sources and metabolic strategies sustain microbial diversity in Antarctic desert soils.

Proc Natl Acad Sci U S A 2021 Nov;118(45)

Department of Microbiology, Monash Biomedicine Discovery Institute, Clayton VIC 3800, Australia;

Numerous diverse microorganisms reside in the cold desert soils of continental Antarctica, though we lack a holistic understanding of the metabolic processes that sustain them. Here, we profile the composition, capabilities, and activities of the microbial communities in 16 physicochemically diverse mountainous and glacial soils. We assembled 451 metagenome-assembled genomes from 18 microbial phyla and inferred through Bayesian divergence analysis that the dominant lineages present are likely native to Antarctica. Read More

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November 2021

Early Eukaryotes in the Lakhanda Biota (Mesoproterozoic, Southeastern Siberia)-Morphological and Geochemical Evidence.

Dokl Biol Sci 2021 Sep 3;500(1):127-132. Epub 2021 Nov 3.

Borissiak Paleontological Institute, Russian Academy of Sciences, Moscow, Russia.

The Mesoproterozoic Lakhanda Group (~1030 Ma) preserves one of the most diverse communities of pre-Ediacaran eukaryotes. More precisely, the Lakhanda Biota includes more than twenty taxa that have been assigned to eukaryotes with different degrees of confidence. Eight of these taxa meet current criteria for the identification of eukaryotic fossils in ancient records. Read More

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September 2021

The aquaculture supply chain in the time of covid-19 pandemic: Vulnerability, resilience, solutions and priorities at the global scale.

Environ Sci Policy 2022 Jan 27;127:98-110. Epub 2021 Oct 27.

South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, China.

The COVID-19 global pandemic has had severe, unpredictable and synchronous impacts on all levels of perishable food supply chains (PFSC), across multiple sectors and spatial scales. Aquaculture plays a vital and rapidly expanding role in food security, in some cases overtaking wild caught fisheries in the production of high-quality animal protein in this PFSC. We performed a rapid global assessment to evaluate the effects of the COVID-19 pandemic and related emerging control measures on the aquaculture supply chain. Read More

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January 2022

Toward a Conversational Agent to Support the Self-Management of Adults and Young Adults With Sickle Cell Disease: Usability and Usefulness Study.

Front Digit Health 2021 29;3:600333. Epub 2021 Jan 29.

Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Sickle cell disease (SCD) is the most common genetic blood disorder in the world and affects millions of people. With aging, patients encounter an increasing number of comorbidities that can be acute, chronic, and potentially lethal (e.g. Read More

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January 2021

Survival and abundance of polar bears in Alaska's Beaufort Sea, 2001-2016.

Ecol Evol 2021 Oct 23;11(20):14250-14267. Epub 2021 Sep 23.

U.S. Geological Survey Alaska Science Center Anchorage AK USA.

The Arctic Ocean is undergoing rapid transformation toward a seasonally ice-free ecosystem. As ice-adapted apex predators, polar bears () are challenged to cope with ongoing habitat degradation and changes in their prey base driven by food-web response to climate warming. Knowledge of polar bear response to environmental change is necessary to understand ecosystem dynamics and inform conservation decisions. Read More

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October 2021

Variation in parasite resistance of Arctic charr, , between and within sympatric morphs.

Ecol Evol 2021 Oct 14;11(20):14024-14032. Epub 2021 Sep 14.

Department of Aquaculture and Fish Biology Hólar University Sauðárkrókur Iceland.

Genetic variation in resistance against parasite infections is a predominant feature in host-parasite systems. However, mechanisms maintaining genetic polymorphism in resistance in natural host populations are generally poorly known. We explored whether differences in natural infection pressure between resource-based morphs of Arctic charr () have resulted in differentiation in resistance profiles. Read More

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October 2021

YG-1 Extract Improves Acute Pulmonary Inflammation by Inducing Bronchodilation and Inhibiting Inflammatory Cytokines.

Nutrients 2021 Sep 28;13(10). Epub 2021 Sep 28.

Hanbang Cardio-Renal Research Center & Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan 54538, Korea.

YG-1 extract used in this study is a mixture of , , and . The present study was designed to investigate the effect of YG-1 extract on bronchodilatation (ex vivo) and acute bronchial and pulmonary inflammation relief (in vivo). Ex vivo: The bronchodilation reaction was confirmed by treatment with YG-1 concentration-accumulation (0. Read More

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September 2021

Nutrient Inputs Stimulate Mercury Methylation by Syntrophs in a Subarctic Peatland.

Front Microbiol 2021 4;12:741523. Epub 2021 Oct 4.

Department of Biochemistry and Microbiology, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States.

Climate change dramatically impacts Arctic and subarctic regions, inducing shifts in wetland nutrient regimes as a consequence of thawing permafrost. Altered hydrological regimes may drive changes in the dynamics of microbial mercury (Hg) methylation and bioavailability. Important knowledge gaps remain on the contribution of specific microbial groups to methylmercury (MeHg) production in wetlands of various trophic status. Read More

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October 2021