5,951 results match your criteria ethanolic extracts


Extract of neem (Azadirachta indica) leaf exhibits bactericidal effect against multidrug resistant pathogenic bacteria of poultry.

Vet Med Sci 2021 May 6. Epub 2021 May 6.

Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.

The aim of the study was to determine the efficacy of neem leaf extract against multidrug resistant (MDR) pathogenic bacteria. Laboratory stock culture of Pasteurella multocida, Salmonella pullorum, Salmonella gallinarum and Escherichia coli was revived. Antibiogram profiles of these bacteria were determined by disc diffusion method. Read More

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Evaluation of Antibacterial Activity of Aqueous, Ethanolic and Methanolic Extracts Areca Nut Fruit on Selected Bacteria.

Biomed Res Int 2021 16;2021:6663399. Epub 2021 Apr 16.

Department of Chemistry, Tabriz Branch, Islamic Azad University, Tabriz, Iran.

Today, the tendency to use of natural preservatives to increase food security has expanded. In the present study, antibacterial effects of Areca Nut fruit extracts were evaluated against , , , and bacteria using agar disc diffusion technique. Methanol, ethanol, and water were used as solvents for extraction by maceration method, and extracts were analyzed by GC-MS. Read More

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Drying methodology effect on the phenolic content, antioxidant activity of Myrtus communis L. leaves ethanol extracts and soybean oil oxidative stability.

BMC Chem 2021 May 5;15(1):31. Epub 2021 May 5.

Higher School of Food Industries of Tunis (ESIAT), University of Carthage, 58 Avenue Alain Savary, 1003, Tunis El Khadra, Tunisia.

In this study, different drying methodologies (convective air, oven and microwave) of Myrtus communis L. (M. communis L. Read More

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Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study.

Arch Microbiol 2021 May 5. Epub 2021 May 5.

Faculty of Science, Department of Chemistry, Karadeniz Technical University, 61080, Trabzon, Turkey.

The angiotensin-converting enzyme (ACE)-related carboxypeptidase, ACE-II, is a type I integral membrane protein of 805 amino acids that contains 1 HEXXH-E zinc binding consensus sequence. ACE-II has been implicated in the regulation of heart function and also as a functional receptor for the coronavirus that causes the severe acute respiratory syndrome (SARS). In this study, the potential of some flavonoids presents in propolis to bind to ACE-II receptors was calculated with in silico. Read More

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Annona muricata silver nanoparticles exhibit strong anticancer activities against cervical and prostate adenocarcinomas through regulation of CASP9 and the CXCL1/CXCR2 genes axis.

Tumour Biol 2021 ;43(1):37-55

Department of Molecular Biology and Biotechnology, Pan African University Institute for Basic Sciences, Technology and Innovation, Nairobi, Kenya.

Background: Green synthesized nanoparticles have been earmarked for use in nanomedicine including for the development of better anticancer drugs.

Objective: The aim of this study was to undertake biochemical evaluation of anticancer activities of green synthesized silver nanoparticles (AgNPs) from ethanolic extracts of fruits (AgNPs-F) and leaves (AgNPs-L) of Annona muricata.

Methods: Previously synthesized silver nanoparticles were used for the study. Read More

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January 2021

Characterization of the chemical profile and the effects of ethanolic extracts of Maytenus ilicifolia Mart. ex Reissek on glucose metabolism in normal hyperglycemic rats.

J Ethnopharmacol 2021 Apr 29;276:114173. Epub 2021 Apr 29.

Western Higher Education Center, Santa Catarina State University - UDESC, Brazil. Electronic address:

Ethnopharmacological Relevance: Maytenus ilicifolia Mart. ex Reissek, Celastraceae, is popularly known as "espinheira-santa" and used to treat pathologies related to the stomach. However, in popular culture, this species has also been used to treat other disorders such as diabetes, but without scientific evidence, requiring more phytochemical and pharmacological studies on the plant. Read More

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Toxicity Bioassay and Cytotoxic Effects of the Benthic Marine Dinoflagellate .

J Xenobiot 2021 Apr 27;11(2):33-45. Epub 2021 Apr 27.

Alfred-Wegener-Institut, Helmholtz-Zentrum für Polar-und Meeresforschung, 27570 Bremerhaven, Germany.

Benthic dinoflagellates produce a wide array of bioactive compounds, primarily polyketides, that cause toxic effects on human consumers of seafood and perhaps mediate species interactions in the benthic microenvironment. This study assesses toxic and other bioactive effects of the benthic dinoflagellate (strain AA60) in two targeted bioassays. The brine shrimp () bioassay revealed lethal effects of direct exposure to live dinoflagellate cells (Treatment A) and even higher potency with ethanolic extracts of lysed cells (Treatment D). Read More

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Co-Microencapsulated Black Rice Anthocyanins and Lactic Acid Bacteria: Evidence on Powders Profile and In Vitro Digestion.

Molecules 2021 Apr 28;26(9). Epub 2021 Apr 28.

Faculty of Food Science and Engineering, Dunarea de Jos University of Galati, Romania, 111 Domneasca Street, 800201 Galati, Romania.

Two multi-functional powders, in terms of anthocyanins from black rice ( L.) and lactic acid bacteria () were obtained through co-microencapsulation into a biopolymer matrix composed of milk proteins and inulin. Two extracts were obtained using black rice flour as a raw material and hot water and ethanol as solvents. Read More

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Screening of Antioxidative Properties and Inhibition of Inflammation-Linked Enzymes by Aqueous and Ethanolic Extracts of Plants Traditionally Used in Wound Healing in Poland.

Antioxidants (Basel) 2021 Apr 28;10(5). Epub 2021 Apr 28.

Department of Pharmacognosy and Molecular Basis of Phytotherapy, Warsaw Medical University, Banacha 1, 02-097 Warsaw, Poland.

A wide range of plant-derived preparations have been used against skin inflammatory disorders and as wound healing agents in traditional medicine. The purpose of the study was to determine the antioxidant activity of aqueous and 70% ethanolic extracts from eleven species of plants traditionally used in Poland to treat inflammatory skin diseases. The ability of extracts to scavenge 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), hydrogen peroxide (HO), and superoxide anion (O), was studied. Read More

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Neuroprotective Assessment of Leaves Extract against Oxidative-Stress-Induced Cytotoxicity in SHSY5Y Neuroblastoma Cells.

Plants (Basel) 2021 Apr 28;10(5). Epub 2021 Apr 28.

Department of Biotechnology, Faculty of Technology, Khon Kaen University, Khon Kaen 40002, Thailand.

The current trend worldwide is searching plant extracts towards prevention of neurodegenerative disorders. This study aimed to investigate the neuroprotective effect of leaves (ALE), rhizomes (ARE), seeds (VSE), leaves (MLE), leaves (PLE) and rhizomes (PRE) ethanolic extracts on human neuroblastoma (SHSY5Y) cells. The 1-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging of VSE and MLE were 81% and 58%, respectively. Read More

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Valorisation of L. Olive Leaves through the Evaluation of Their Extracts: Antioxidant and Antimicrobial Activity.

Foods 2021 Apr 28;10(5). Epub 2021 Apr 28.

Food Science and Technology Department, Universidad de Córdoba, Darwin Building, 14014 Córdoba, Spain.

L. leaves constitute a source of bioactive compounds with recognized benefits for both human health and technological purposes. In the present work, different extracts from olive leaves were obtained by the application of two extraction methods, Soxhlet and microwave-assisted extraction (MAE), and six solvents (distilled water, ethanolic and glycerol mixtures solvents). Read More

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Neuroprotective and Antioxidant Enhancing Properties of Selective Extracts.

Molecules 2021 Apr 28;26(9). Epub 2021 Apr 28.

Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania.

The sterile stems belonging to the species are often used in traditional medicine of various nations, including Romanians. They are highly efficient in treating urinary tract infections, cardiovascular diseases, respiratory tract infections, and medical skin conditions due to their content of polyphenolic derivatives that have been isolated. In this regard, this study aimed to provide the chemical composition of the extracts obtained from the species (, , ) and to investigate the biological action in vitro and in vivo. Read More

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Phytochemical Analysis, Pharmacological and Safety Evaluations of Halophytic Plant, .

Molecules 2021 Apr 20;26(8). Epub 2021 Apr 20.

Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Qassim 51452, Saudi Arabia.

, an edible halophyte, is traditionally used for inflammation and pain. To confirm the claimed anti-inflammatory and analgesic properties, a detailed study on respective pharmacological actions was undertaken. The activities are contemplated to arise from its phytoconstituents. Read More

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Effects of Drying Methods on Antioxidant, Anti-Inflammatory, and Anticancer Potentials of Phenolic Acids in Lovage Elicited by Jasmonic Acid and Yeast Extract.

Antioxidants (Basel) 2021 Apr 24;10(5). Epub 2021 Apr 24.

Department of Biochemistry and Food Chemistry, University of Life Sciences in Lublin, Skromna 8, 20-704 Lublin, Poland.

The study presents the effect of drying methods (traditional, convection, microwave, and freeze-drying) on the content and bioactivity (determined as antioxidative, anti-inflammatory, and antiproliferative potential) of potentially bioavailable fractions of phenolic acids contained in lovage elicited with jasmonic acid (JA) and yeast extract (YE) and in untreated control leaves. The highest amount of syringic acid was recorded in the convectionally dried lovage samples, while ethanolic extracts from lyophilized lovage had the highest content of protocatechuic and caffeic acids. The drying method significantly influenced the tested properties only in some cases. Read More

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LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kınkor ().

Molecules 2021 Apr 23;26(9). Epub 2021 Apr 23.

Department of Chemistry, Faculty of Science, Ataturk University, 25240 Erzurum, Turkey.

Kınkor () is Turkish medicinal plant species and used in folk medicine against some diseases. As far as we know, the data are not available on the biological activities and chemical composition of this medicinal plant. In this study, the phytochemical composition; some metabolic enzyme inhibition; and antidiabetic, anticholinergic, and antioxidant activities of this plant were assessed. Read More

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Antioxidant Activity of Frozen and Freeze-Dried Drone Brood Homogenate Regarding the Stage of Larval Development.

Antioxidants (Basel) 2021 Apr 22;10(5). Epub 2021 Apr 22.

Department of Chemistry and Food Toxicology, Institute of Food Technology and Nutrition, University of Rzeszów, Ćwiklińskiej 1a St., 35-601 Rzeszów, Poland.

Drone brood is a little-known and poorly studied bee product used and valued in the treatment of many diseases, including male infertility and women's menopausal disorders. The aim of this study was to evaluate the antioxidant activity of drone brood depending on the stage of larval development and the method of preservation. Aqueous and ethanolic homogenate extracts of drone brood were assayed for antioxidant activity (with the DPPH, FRAP, and ABTS methods), polyphenol, and flavonoid content. Read More

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Antioxidant, Antidiabetic, and Antiobesity Properties, TC7-Cell Cytotoxicity and Uptake of (Marcela) Conventional and High Pressure-Assisted Extracts.

Foods 2021 Apr 19;10(4). Epub 2021 Apr 19.

Departamento de Ciencia y Tecnología de Alimentos, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.

The growing incidence of non-communicable diseases makes the search for natural sources of bioactive compounds a priority for such disease prevention/control. ('marcela'), a plant rich in polyphenols and native to Brazil, Uruguay, Paraguay, and Argentina, could be used for this purpose. Data on its antidiabetic/antiobesity properties and cellular uptake of bioactive compounds are lacking. Read More

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Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2.

Biology (Basel) 2021 Apr 11;10(4). Epub 2021 Apr 11.

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Steroid 5-alpha reductases (SRD5As) are responsible for the conversion of testosterone to dihydrotestosterone, a potent androgen, which is the aetiologic factor of androgenetic alopecia. This study aimed to compare the gene expression suppression activity exerted by Thai rice bran extracts and their components and investigate the interactional mechanism between bioactive compounds and SRD5A2 using molecular dynamics (MD) simulation. Bran of cv. Read More

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High Throughput Profiling of Flavonoid Abundance in Residue-Valorizing under Explored Mexican Plant.

Plants (Basel) 2021 Apr 3;10(4). Epub 2021 Apr 3.

Programa Catedra CONACYT-CIBNOR, Av. Instituto Politécnico Nacional 195, Playa Palo Santa Rita Sur, La Paz 23096, Mexico.

waste biomass () is an undervalued abundant plant material with natural active compounds such as flavonoids. Hence, the search and conservation of flavonoids through the different productive areas have to be studied to promote the use of this agro-residue for industrial purposes. In this work, we compared the proportion of total flavonoid content (TFC) among the total polyphenolics (TPC) and described the variation of specific flavonoid profiles (HPLC-UV-MS/MS) of from three locations. Read More

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In Vitro Screening of East Asian Plant Extracts for Potential Use in Reducing Ruminal Methane Production.

Animals (Basel) 2021 Apr 4;11(4). Epub 2021 Apr 4.

Department of Ecofriendly Livestock Science, Institute of Green Bio Science and Technology, Seoul National University, Pyeongchang 25354, Gangwon-do, Korea.

Indiscriminate use of antibiotics can result in antibiotic residues in animal products; thus, plant compounds may be better alternative sources for mitigating methane (CH) production. An in vitro screening experiment was conducted to evaluate the potential application of 152 dry methanolic or ethanolic extracts from 137 plant species distributed in East Asian countries as anti-methanogenic additives in ruminant feed. The experimental material consisted of 200 mg total mixed ration, 20 mg plant extract, and 30 mL diluted ruminal fluid-buffer mixture in 60 mL serum bottles that were sealed with rubber stoppers and incubated at 39 °C for 24 h. Read More

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Bromelain and Olea europaea (L.) leaf extract mediated alleviation of benzo(a)pyrene induced lung cancer through Nrf2 and NFκB pathway.

Environ Sci Pollut Res Int 2021 Apr 23. Epub 2021 Apr 23.

Immunology Microbiology Lab, Department of Human Physiology, Tripura University, Suryamaninagar Tripura, 799022, India.

Lung cancer is the most aggressive as well as deadly form of cancer and most of the lung cancer cases are involved in direct smoking or passive smoking. Oxidative stress and pulmonary inflammation regulated by some transcription factors like Nrf2, NF-κB etc. play important roles in lung cancer. Read More

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A comparative study of Caesalpinia bonduc (L.) Roxb. root extracts on sexual behaviour in male Wistar rats.

Andrologia 2021 Apr 23:e14072. Epub 2021 Apr 23.

Institute of Modeling and Analysis in Geo-environmental and Health, Perpignan Via Domitia University, Perpignan, France.

Caesalpinia bonduc is among the traditionally used plant in Benin, for its enhancement of male sexual activity. This study was undertaken to investigate the potential effect of C. bonduc root extracts on sexual behaviour of male Wistar rats. Read More

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Antimicrobial activity of bioactive compounds of and against human pathogenic microorganisms.

Iran J Microbiol 2021 Feb;13(1):98-103

Department of Microbiology, Faculty of Health Sciences, University of Talca, Talca, Chile.

Background And Objectives: and are medicinal shrubs native to Chile and are popularly known as "Bailahuén". Regularly, this plant is used for liver, digestive and renal affections, as well as colds and the cleaning of infected wounds. The aim of the study was to identify the responsible compounds for the antimicrobial activity of and

Materials And Methods: Infusions and ethanolic extracts of and were analysed by thin-layer chromatography bioautography (TLC-B) to determine the compounds responsible for the antimicrobial activity against Gram-positive and Gram-negative bacterial strains and yeasts of Bailahuén. Read More

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February 2021

Larvicidal activity of Maytenus guianensis (Celastraceae) against Aedes aegypti (Diptera: Culicidae).

Rev Soc Bras Med Trop 2021 12;54:e0835. Epub 2021 Apr 12.

Universidade Federal de Rondônia, Laboratório de Bioecologia de Insetos, Departamento de Biologia, Porto Velho, RO, Brasil.

Introduction: Bioprospection of plant products is used to discover new insecticides.

Methods: The larvicidal activity of ethanolic extract and triterpene (tingenone B) from the bark of Maytenus guianensis and their effect on pupation and emergence were evaluated against Aedes aegypti.

Results: Crude extract LC50 was 11. Read More

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A comprehensive assessment of the chemical composition, antioxidant, genoprotective and antigenotoxic activities of Lamiaceae species using different experimental models in vitro.

Food Funct 2021 Apr 23;12(7):3233-3245. Epub 2021 Mar 23.

Institute of Botany and Botanical Garden "Jevremovac", Chair of Plant Morphology and Systematics, Faculty of Biology, University of Belgrade, Belgrade, Serbia.

This research was aimed to assess the potential of Glechoma hederacea, Hyssopus officinalis, Lavandula angustifolia, Leonurus cardiaca, Marrubium vulgare and Sideritis scardica (Lamiaceae) methanolic, ethanolic and aqueous extracts against the damaging effects of oxidative stress using different experimental models. The chemical characterization was done spectrophotometrically by quantifying total phenolics, phenolic acids, flavonoids and flavonols in the extracts, as well as by employing HPLC-DAD technique. Moreover, DPPH assay was used to assess the extracts' radical scavenging potential. Read More

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Comparative lipid and uric acid suppressing properties of four common herbs in high fat-induced obese mice with their total phenolic and flavonoid index.

Biochem Biophys Rep 2021 Jul 30;26:100990. Epub 2021 Mar 30.

Faculty of Science, Department of Pharmacy, Noakhali Science and Technology University, Noakhali-3814, Bangladesh.

Our present study was designed to investigate the comparative anti-obesity efficacy of ethanolic extract of , , L. and in high fat-induced mice with their total phenolic and flavonoid profile. Total phenolic and flavonoid content were determined by Folin-Ciocalteu's and Aluminium chloride UV method respectively. Read More

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Neem Leaf ( A. Juss) Ethanolic Extract on the Liver and Kidney Function of Rats.

ScientificWorldJournal 2021 30;2021:7970424. Epub 2021 Mar 30.

Laboratory of Pathology, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.

Neem ( A. Juss) is one of the tropical plants found in Indonesia that has been used to prevent and treat various diseases. This study aimed to investigate the effect of the ethanol extract of neem leaves on the concentration of aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, and creatinine in male rats. Read More

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Acute toxicity studies and protective effects of bark extract in streptozotocin-induced diabetic rats.

Drug Chem Toxicol 2021 Apr 13:1-11. Epub 2021 Apr 13.

Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, India.

The medicinal properties of () bark have been reported for their clinical importance for many diseases including diabetes. However, there is no clear evidence so far regarding dose selection for its hepato- and nephroprotective effect in diabetic condition. Hence, the present study aims at evaluating antioxidant activity, the acute toxicity, and dose fixation of bark for their effective medicinal values in streptozotocin (STZ)-induced rats. Read More

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Natural photosensitizers from Tripterygium wilfordii and their antimicrobial photodynamic therapeutic effects in a Caenorhabditis elegans model.

J Photochem Photobiol B 2021 May 29;218:112184. Epub 2021 Mar 29.

Natural Product Informatics Research Center, Gangneung Institute of Natural Products, Korea Institute of Science and Technology, Gangwon-do 25451, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology (UST), Gangneung, Gangwon-do 25451, Republic of Korea. Electronic address:

Tripterygium wilfordii Hook. f. is a traditional medicinal plant and has long been used in East Asia to treat many diseases. Read More

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Novel Prosopis juliflora leaf ethanolic extract as natural antimicrobial agent against food spoiling microorganisms.

Sci Rep 2021 Apr 12;11(1):7871. Epub 2021 Apr 12.

Department of Biological and Environmental Sciences, College of Art and Science, Qatar University, P.O. Box 2713, Doha, Qatar.

Fresh produces spoilage is a worldwide concern that accompany the global increase in food demand. Adverse human health and environmental effects of commercial spoilage control agents are major public concern. In this study, Prosopis juliflora leaves and fruit extracts had their antimicrobial activities evaluated against the growth of selected bacteria and yeast, and against mycelial growth and conidial germination of selected mycotoxins-producing fungi. Read More

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