14,739 results match your criteria ethanol extract

Study on effects of sweating treatment and different drying methods on the quality of Gentianae macrophyllae Radix.

Sci Rep 2021 May 6;11(1):9717. Epub 2021 May 6.

College of Life Science, Northwest University, North Tabai Road, Beilin District, Xi'an, 710069, People's Republic of China.

To provide basis for improving the quality of Gentianae macrophyllae Radix and optimising the field processing method. Gentianae macrophyllae Radix samples were collected from Long County. Five main active iridoids were determined by using HPLC. Read More

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Pulsed electric field assisted process for extraction of bioactive compounds from custard apple (Annona squamosa) leaves.

Food Chem 2021 Apr 28;359:129976. Epub 2021 Apr 28.

International Center of Excellence in Seafood Science and Innovation, Faculty of Agro-Industry, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand. Electronic address:

Impact of pulsed electric field (PEF) assisted process on preparation of custard apple leaf extract (CALE) using ethanol (70%, v/v) was studied. Different electric field strengths (2-6 kV/cm), pulse numbers (100-300 pulses) with specific energies (45-142 kJ/kg) for 2.5 to 5 min were implemented. Read More

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species suppress nitric oxide production in LPS-stimulated RAW 264.7 macrophages.

Nat Prod Res 2021 May 6:1-5. Epub 2021 May 6.

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.

Aerial parts and roots from three species were extracted with 70% ethanol. The phytochemical composition was investigated using GC-MS and multivariate data analysis. The total phenolic and flavonoid contents were also assessed. Read More

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Evaluation of Antibacterial Activity of Aqueous, Ethanolic and Methanolic Extracts Areca Nut Fruit on Selected Bacteria.

Biomed Res Int 2021 16;2021:6663399. Epub 2021 Apr 16.

Department of Chemistry, Tabriz Branch, Islamic Azad University, Tabriz, Iran.

Today, the tendency to use of natural preservatives to increase food security has expanded. In the present study, antibacterial effects of Areca Nut fruit extracts were evaluated against , , , and bacteria using agar disc diffusion technique. Methanol, ethanol, and water were used as solvents for extraction by maceration method, and extracts were analyzed by GC-MS. Read More

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Protective effects of seed ethanol extract on aluminum chloride-induced testosterone, testicular and hematological changes in an experimental male rat model.

Vet Res Forum 2021 15;12(1):7-13. Epub 2021 Mar 15.

Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria.

The study was done to ascertain the protective potentials of ethanol seed extract of on aluminum chloride-induced reproductive and hematological toxicities. Thirty mature male rats were used for the study. They were assigned into five groups (n = 6). Read More

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Drying methodology effect on the phenolic content, antioxidant activity of Myrtus communis L. leaves ethanol extracts and soybean oil oxidative stability.

BMC Chem 2021 May 5;15(1):31. Epub 2021 May 5.

Higher School of Food Industries of Tunis (ESIAT), University of Carthage, 58 Avenue Alain Savary, 1003, Tunis El Khadra, Tunisia.

In this study, different drying methodologies (convective air, oven and microwave) of Myrtus communis L. (M. communis L. Read More

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Propolis Extract Regulate microRNA Expression in Glioblastoma and Brain Cancer Stem Cells.

Anticancer Agents Med Chem 2021 May 3. Epub 2021 May 3.

Ege University, Faculty of Medicine, Department of Pediatrics, Izmir, Turkey.

Background: Grade IV gliomas are classified as glioblastoma (GBM), which is the most malignant brain cancer type. Various genetic and epigenetic mechanisms play a role in the initiation and progression of GBM. MicroRNAs (miRNAs) are small, non-coding RNA molecules that are the main epigenetic regulatory RNA class. Read More

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Comparative study of antimicrobial action of aloe vera and antibiotics against different bacterial isolates from skin infection.

Vet Med Sci 2021 May 5. Epub 2021 May 5.

Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.

Background: We aimed to investigate the prevalence of Aloe Vera gel extract and antibiotic resistance against in Escherichia coli, Shigella, Salmonella spp and Staphylococcus aureus were isolated from animal's skin infection.

Objective: The purpose of this study was has been designed to check the antibacterial effect of Aloe Vera against some common skin pathogens, and its comparison to commonly used antibiotics, with the aim to provide the cheap source of medication.

Material And Methods: We performed a prospective study to determine 150 Skin infections were isolates obtained from septic wounds with sterile cotton swab at different Animal and applied to freshly prepared slants of nutrient agar, Mannitol Salt agar (Oxoid), and further conformation Catalase and a coagulase test were performed for biochemical characterization. Read More

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Periplocin and cardiac glycosides suppress the unfolded protein response.

Sci Rep 2021 May 4;11(1):9528. Epub 2021 May 4.

Department of Cell Signaling, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, 467-8603, Japan.

The unfolded protein response (UPR) controls protein homeostasis through transcriptional and translational regulation. However, dysregulated UPR signaling has been associated with the pathogenesis of many human diseases. Therefore, the compounds modulating UPR may provide molecular insights for these pathologies in the context of UPR. Read More

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ROS-Mediated Anti-Tumor Effect of Coptidis Rhizoma against Human Hepatocellular Carcinoma Hep3B Cells and Xenografts.

Int J Mol Sci 2021 Apr 30;22(9). Epub 2021 Apr 30.

Anti-Aging Research Center, Dongeui University, Busan 47340, Korea.

Coptidis Rhizoma is the dried rhizome from the Franch. that has been shown to have a number of beneficial pharmacological properties including antioxidant, anti-inflammatory, and anti-cancer effects. However, the anti-cancer effects of Coptidis Rhizoma on hepatocellular carcinoma (HCC) remain unclear. Read More

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First Report of Fusarium ipomoeae Causing Peanut leaf Spot in China.

Plant Dis 2021 May 4. Epub 2021 May 4.

Shandong Peanut Research Institute , Plant Protect, No. 126 Wannianquan Road, Licang, Qingdao, Shandong, 266100, China, Qingdao, Shandong Province, China, 266100.

Peanut (Arachis hypogaea L.) is one of the most economically important crops as an important source of edible oil and protein. In August 2020, circular to oval-shaped brown leaf spots (2-6 mm in diameter) with well-defined borders surrounded by a yellow margin were observed on peanut plant leaves in Laixi City, Shandong Province, China. Read More

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Purification of polysaccharides from by using an aqueous two-phase system and evaluation of the physicochemical and antioxidant properties of polysaccharides .

Prep Biochem Biotechnol 2021 May 3:1-10. Epub 2021 May 3.

School of Food & Biological Engineering, Jiangsu University, Zhenjiang, China.

In this study, polysaccharides (PLPS) and proteins were simultaneously separated from . mycelia by using an aqueous two-phase system (ATPS) based on choline chloride ([Chol]Cl)/KHPO, and the physicochemical and antioxidant properties of PLPS after ATPS extraction were evaluated. Results demonstrated that the maximal extraction efficiencies of 68. Read More

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Iridoid compounds from the aerial parts of Franch. with cytotoxic activity.

Nat Prod Res 2021 May 6;35(9):1544-1549. Epub 2019 Sep 6.

Institute of Biomechanics and Medical Engineering, Tsinghua University, Beijing, China.

One new secoiridoid compound swertiamarin B (), along with a known compound lytanthosalin (), were isolated from ethanol extract of the aerial parts of . Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were first isolated from the genus. Read More

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A facile macroporous resin-based method for separation of yellow and orange pigments.

Food Sci Biotechnol 2021 Apr 8;30(4):545-553. Epub 2021 Mar 8.

College of Life Science, Yangtze University, Jingzhou, 434025 Hubei China.

The yellow pigments (YMPs) named monascin and ankaflavin and the orange pigments (OMPs) named rubropunctatin and monascorubrin are two groups of bioactive components in a mixture state in the fermented products. In order to separate these two groups of bioactive pigments, a facile macroporous resin-based method was developed. The weak-polar resin CAD-40 was selected from the seven tested macroporous resins as it revealed better properties for the adsorption and desorption of the YMPs and OMPs. Read More

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Danggui-Shaoyao-San (DSS) Ameliorates Cerebral Ischemia-Reperfusion Injury via Activating SIRT1 Signaling and Inhibiting NADPH Oxidases.

Front Pharmacol 2021 15;12:653795. Epub 2021 Apr 15.

Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.

Danggui-Shayao-San (DSS) is a famous Traditional Chinese Medicine formula that used for treating pain disorders and maintaining neurological health. Recent studies indicate that DSS has neuroprotective effects against ischemic brain damage but its underlining mechanisms remain unclear. Herein, we investigated the neuroprotective mechanisms of DSS for treating ischemic stroke. Read More

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A Review of the Toxicity and Phytochemistry of Medicinal Plant Species Used by Herbalists in Treating People Living With HIV/AIDS in Uganda.

Front Pharmacol 2021 15;12:615147. Epub 2021 Apr 15.

Institute for Virology, University Clinics and Faculty of Medicine, University of Leipzig, Leipzig, Germany.

Despite concerns about toxicity, potentially harmful effects and herb-drug interactions, the use of herbal medicines remains widely practiced by people living with HIV/AIDS (PLHIV) in Uganda. The objective of the paper was to comprehensively review the literature on the toxicity and chemical composition of commonly used medicinal plant species in treating PLHIV in Uganda. We reviewed relevant articles and books published over the last sixty years on ethnobotany, antiviral/anti-HIV activity, toxicity, phytochemistry of , , , , , , , , , and and their synonyms. Read More

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Cytotoxic, Cellular Antioxidant, and Antiglucuronidase Properties of the Ethanol Leaf Extract from .

ScientificWorldJournal 2021 14;2021:6622318. Epub 2021 Apr 14.

School of Biology and Environmental Sciences, University of Mpumalanga, Private Bag X11283, Mbombela 1200, South Africa.

(L.) Spreng (Xanthorrhoeaceae family), popularly known in South Africa as "ibhucu" or "Balsamkopieva," is a perennial plant traditionally used to treat skin diseases, including sunburns, rough skin, dressing burns, itches, and aging. The present study reports the cytotoxic, cellular antioxidant, and antiglucuronidase properties of the ethanol leaf extract from . Read More

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Histopathological evaluation of Rusby in 7,12-dimethylbenz(α) anthracene-induced breast cancer in female rats.

Vet World 2021 Mar 6;14(3):569-577. Epub 2021 Mar 6.

Department of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, India.

Background And Aim: Rusby (SrR) is a medicinal plant of the Asteraceae family and traditionally consumed as infusion in the Andean region from Peru for inflammatory disorders. This study aimed to determine the histopathological changes afforded by SrR in 7, 12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer (BC) in rats.

Materials And Methods: An ethanolic extract of SrR aerial parts was prepared by maceration with 96% ethanol, and the chemical components were identified by gas chromatography coupled to mass spectrometry; the antioxidant activity was determined by 1,1-diphenyl-2-picril-hidrazil (DPPH) assay; and the acute toxicity was assessed according to the OCED 423 guidelines. Read More

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The biologically active compound of (L.) Dunal, docosanyl ferulate, is endowed with potent anxiolytic properties but devoid of typical benzodiazepine-like side effects.

J Psychopharmacol 2021 May 3:2698811211008588. Epub 2021 May 3.

Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.

Background: Clinical and experimental studies support the therapeutic potential of () (L.) Dunal on anxiety disorders. This potential is attributable to components present in different plant extracts; however, the individual compound(s) endowed with specific anxiolytic effects and potential modulatory activity of the GABA receptor complex (GABAR) have remained unidentified until the recent isolation from a WS methanolic root extract of some GABAR-active compounds, including the long alkyl-chain ferulic acid ester, docosanyl ferulate (DF). Read More

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First Report of Bacterial Soft Rot Disease on Taro Caused by in China.

Plant Dis 2021 May 2. Epub 2021 May 2.

South China Agricultural University, 12526, Guangdong Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre,, Guangzhou, Guangdong, China.

Taro [ (L.) Schott.] is an important root crop in the world with great economic value. Read More

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Comparison of ultrasound and microwave assisted extraction of diosgenin from Trigonella foenum graceum seed.

Ultrason Sonochem 2021 Apr 22;74:105572. Epub 2021 Apr 22.

Sant Longowal Institute of Engineering and Technology, Longowal, Punjab 148106, India. Electronic address:

From the recent market trend, there is a huge demand for the bioactive compounds from various food matrices that could be capable enough to combat the emerging health effects in day-to-day life. Fenugreek is a well-known spice from ancient times for its medicinal and health benefits. In the present study, two methods of green extraction microwave (MAE) and ultrasound (UAE) assisted were studied in regard of extraction of fenugreek diosgenin. Read More

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8-hydroxypinoresinol-4-O-β-D-glucoside from Valeriana officinalis L. Is a Novel Kv1.5 Channel Blocker.

J Ethnopharmacol 2021 Apr 28;276:114168. Epub 2021 Apr 28.

The Macrohard Institute of Health, 231 North Ave, Battle Creek, MI, 49017, USA; The American Academy of Tradition Chinese Medicine Inc., 1925 W County Rd B2, Roseville, MN, 55113, USA. Electronic address:

Ethnopharmacology Relevance: In folkloric medicine of many cultures, one of the medical uses of Valeriana officinalis Linn is to treat heart-related disease. Recently, it was shown that the ethanol extracts from V. officinalis could effectively prevent auricular fibrillation, and 8-hydroxypinoresinol-4-O-β-D-glucoside (HPG) from the extracts is one of the two active compounds showing antiarrhythmia activities. Read More

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Secoiridoid glycosides from the fruits of .

Nat Prod Res 2020 Oct 14:1-7. Epub 2020 Oct 14.

Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing, China.

Five new secoiridoid glycosides, cornusphenosides E-I (-), were isolated and characterized from an active fraction of ethanol extract of the fruits of . Their structures were determined by extensive spectroscopic data analysis, including 2 D NMR and HRESIMS experiments. In the preliminary assay, compound (when evaluated at 10 M) showed the neuroprotective effect against HO-induced SH-SY5Y cell damage. Read More

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October 2020

Four new polyacetylenes from the roots of .

Nat Prod Res 2021 Jan 10:1-8. Epub 2021 Jan 10.

Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin, P.R. China.

Four new polyacetylene substances, sadivaethynes A-D, were isolated from the ethanol extract of the roots of (Turcz.) Schischk using repeated column chromatography. Structural elucidation of compounds was established by 1D and 2D NMR spectra referring to the literature, together with high-resolution mass spectrometric analysis. Read More

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January 2021

Facile production of chlorophyllides using recombinant CrCLH1 and their cytotoxicity towards multidrug resistant breast cancer cell lines.

PLoS One 2021 30;16(4):e0250565. Epub 2021 Apr 30.

Department of Biological Science and Technology, I-Shou University, Kaohsiung, Taiwan.

The purity of chlorophylls plays one of the key role for the production of chlorophyllides. We have designed a facile method for chlorophyll purification by twice solvent extraction. Twice extraction causes the loss of chlorophylls, but the purity of total chlorophylls can be enhanced 182%. Read More

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Evaluation of Antiulcer Activity of Hydro-Methanol Extract and Solvent Fractions of the Stem Bark of (Moraceae) on Rodent Models.

Biomed Res Int 2021 9;2021:6685395. Epub 2021 Apr 9.

Department of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Introduction: The stem bark of is used by Ethiopian traditional healers and the community for the treatment of peptic ulcer disease. Thus, the current study was aimed at evaluating the antiulcer effect of hydro-methanol extract and solvent fractions of .

Methods: The stem bark of was collected and shed dried. Read More

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Roxb. Ethanol Extract Has Anti-Inflammatory and Hepatoprotective Effects In Vitro and In Vivo by Targeting the IRAK1/AP-1 Pathway.

Molecules 2021 Apr 26;26(9). Epub 2021 Apr 26.

Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.

Roxb. has been used traditionally as a remedy for many diseases, especially inflammation. Therefore, we analyzed and explored the mechanism of the anti-inflammatory effect of a Roxb. Read More

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Co-Microencapsulated Black Rice Anthocyanins and Lactic Acid Bacteria: Evidence on Powders Profile and In Vitro Digestion.

Molecules 2021 Apr 28;26(9). Epub 2021 Apr 28.

Faculty of Food Science and Engineering, Dunarea de Jos University of Galati, Romania, 111 Domneasca Street, 800201 Galati, Romania.

Two multi-functional powders, in terms of anthocyanins from black rice ( L.) and lactic acid bacteria () were obtained through co-microencapsulation into a biopolymer matrix composed of milk proteins and inulin. Two extracts were obtained using black rice flour as a raw material and hot water and ethanol as solvents. Read More

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Physicochemical, Antioxidant, and Anti-Inflammatory Properties of Rapeseed Lecithin Liposomes Loading a Chia ( L.) Seed Extract.

Antioxidants (Basel) 2021 Apr 28;10(5). Epub 2021 Apr 28.

Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), C/José Antonio Novais, 10, 28040 Madrid, Spain.

Vegetal waste materials were used to produce liposomes with both antioxidant and anti-inflammatory properties. Differences in the chemical composition of rapeseed lecithin (LEC) and a partially purified phospholipid fraction (PPL) were studied in terms of fatty acids (neutral lipids, free fatty acids, and phospholipids), sterols, tocopherols, and amino acid composition. Neutral lipids, campesterol, β-sitosterol, and γ-tocopherol were the most depleted compounds in PPL. Read More

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Adsorption and Purification of Baicalin from Georgi Extract by Ionic Liquids (ILs) Grafted Silica.

Molecules 2021 Apr 16;26(8). Epub 2021 Apr 16.

College of Science and Technology, Jiaozuo Teachers College, Jiaozuo 454000, China.

Baicalin which has multiple biological activities is the main active component of the root of Georgi (SBG). Although its isolation and purification by adsorption methods have aroused much interest of the scientific community, it suffered from the poor selectivity of the adsorbents. In this work, an environmentally benign method was developed to prepare ionic liquids (ILs) grafted silica by using IL 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([Cmim]NTf) and ethanol as reaction media. Read More

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