198,377 results match your criteria estimation pp'-ddt


Comparison of the current abattoir surveillance system for detection of paratuberculosis in Australian sheep with quantitative PCR tissue strategies using simulation modelling.

Prev Vet Med 2021 Sep 15;196:105495. Epub 2021 Sep 15.

Faculty of Science, Sydney School of Veterinary Science, The University of Sydney, Camden, NSW, Australia. Electronic address:

Abattoir surveillance for Johne's disease monitoring in Australia has provided valuable feedback to producers about their flock's disease status since its commencement in 1999. The current surveillance system relies on the identification of gross lesions in sheep carcases at an abattoir, followed by sampling and histopathology testing. This manual inspection system has not been adapted to meet the changing disease situation, as infection prevalence levels have declined over time due to vaccination. Read More

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September 2021

Which is the best alternative to estimate muscle mass for sarcopenia diagnosis when DXA is unavailable?

Arch Gerontol Geriatr 2021 Sep 3;97:104517. Epub 2021 Sep 3.

FCNAUP - Faculdade de Ciências da Nutrição e Alimentação, Universidade do Porto, 4150-180 Porto, Portugal; LAETA-INEGI - Faculdade de Engenharia, Universidade do Porto, Porto, Portugal.

Background: Dual x-ray absorptiometry (DXA) is widely adopted to estimate muscle mass for research, but for daily practice is only available in a limited number of facilities.

Aim: To elucidate if it is anthropometry or bioelectrical impedance analysis (BIA) the method more concordant with DXA in estimating muscle mass for sarcopenia diagnosis among older adults, and to investigate the impact of several cut-off points in sarcopenia frequency.

Methods: 159 older adults (≥65 years) were included in a cross-sectional analysis. Read More

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September 2021

Delay discounting, time perspective, and self-schemas in adolescent alcohol drinking and disordered eating behaviors.

Appetite 2021 Sep 18:105703. Epub 2021 Sep 18.

Department of Health Management, I-Shou University, 8 Yida Road, Kaohsiung, 82445, Taiwan. Electronic address:

Delay discounting, time perspective, and self-schemas are well-known predictors of health risk behaviors among adolescents. However, the associations between these constructs and their influence on such behaviors are yet to be examined. This study aimed to determine the relationships among three cognitive constructs, namely, delay discounting, time perspective, and self-schemas, and determine the associations of these constructs with alcohol drinking (alcohol use and alcohol problems) and disordered eating behaviors in adolescents. Read More

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September 2021

Estimating parameters of a stochastic cell invasion model with fluorescent cell cycle labelling using approximate Bayesian computation.

J R Soc Interface 2021 Sep 22;18(182):20210362. Epub 2021 Sep 22.

School of Mathematical Sciences, Queensland University of Technology, Brisbane, Australia.

We develop a parameter estimation method based on approximate Bayesian computation (ABC) for a stochastic cell invasion model using fluorescent cell cycle labelling with proliferation, migration and crowding effects. Previously, inference has been performed on a deterministic version of the model fitted to cell density data, and not all parameters were identifiable. Considering the stochastic model allows us to harness more features of experimental data, including cell trajectories and cell count data, which we show overcomes the parameter identifiability problem. Read More

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September 2021

Comparing the performance of machine learning algorithms for remote and in situ estimations of chlorophyll-a content: a case study in the Tri An Reservoir, Vietnam.

Water Environ Res 2021 Sep 21. Epub 2021 Sep 21.

Ho Chi Minh City University of Technology (HUTECH), Binh Thanh District, Ho Chi Minh City, Vietnam.

Chlorophyll-a (Chl-a) is one of the most important indicators of the trophic status of inland waters, and its continued monitoring is essential. Recently, the operated Sentinel-2 MSI satellite offers high spatial resolution images for remote water quality monitoring. In this study, we tested the performance of the three well-known machine learning (ML) [random forest (RF), support vector machine (SVM), Gaussian process (GP)] and the two novel ML [extreme gradient boost (XGB), CatBoost (CB)] models for estimation a wide-range of Chl-a concentration (10. Read More

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September 2021

The amount of light reaching the leaves in seagrass (Zostera marina) meadows.

PLoS One 2021 21;16(9):e0257586. Epub 2021 Sep 21.

School of Natural Sciences, Technology and Environmental Studies, Södertörn University, Huddinge, Sweden.

Seagrass meadows, and other submerged vegetated habitats, support a wide range of essential ecological services, but the true extents of these services are in many ways still not quantified. One important tool needed to assess and model many of these services is accurate estimations of the systems´ primary productivity. Such productivity estimations require an understanding of the underwater light field, especially regarding the amount of light that actually reaches the plants' photosynthetic tissue. Read More

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September 2021

Stabilization of Discrete-Time Stochastic Delayed Neural Networks by Intermittent Control.

IEEE Trans Cybern 2021 Sep 21;PP. Epub 2021 Sep 21.

This article investigates the stabilization of discrete-time stochastic neural networks with time-varying delay via aperiodically intermittent control (AIC). A comprehensive analysis of the stabilization of discrete-time delayed systems via AIC is provided, where the Lyapunov function method and the Lyapunov-Krasovskii functional method are investigated, respectively. Then, three stabilization criteria are given, which extend previous works from the continuous-time framework to the discrete-time one, and the average activation time ratio (AATR) of AIC is estimated. Read More

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September 2021

GeoDualCNN: Geometry-supporting Dual Convolutional Neural Network for Noisy Point Clouds.

IEEE Trans Vis Comput Graph 2021 Sep 21;PP. Epub 2021 Sep 21.

We propose a geometry-supporting dual convolutional neural network (GeoDualCNN) for both point cloud normal estimation and denoising. GeoDualCNN fuses the geometry domain knowledge that the underlying surface of a noisy point cloud is piecewisely smooth with the fact that a point normal is properly defined only when local surface smoothness is guaranteed. Centered around this insight, we define the homogeneous neighborhood (HoNe) which stays clear of surface discontinuities, and associate each HoNe with a point whose geometry and normal orientation is mostly consistent with that of HoNe. Read More

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September 2021

Joint Multi-Dimension Pruning via Numerical Gradient Update.

IEEE Trans Image Process 2021 Sep 21;PP. Epub 2021 Sep 21.

We present joint multi-dimension pruning (abbreviated as JointPruning), an effective method of pruning a network on three crucial aspects: spatial, depth and channel simultaneously. To tackle these three naturally different dimensions, we proposed a general framework by defining pruning as seeking the best pruning vector (i.e. Read More

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September 2021

Keypoint-Based Disentangled Pose Network for Category-Level 6D Object Pose Tracking.

IEEE Comput Graph Appl 2021 Sep 21;PP. Epub 2021 Sep 21.

Category-level 6D object pose tracking is very challenging in the field of 3D computer vision. Keypoint-based object pose estimation has demonstrated its effectiveness in dealing with it. However, current approaches first estimate the keypoints through a neural network and further compute the inter-frame pose change via least-squares optimization. Read More

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September 2021

Naomi: a new modelling tool for estimating HIV epidemic indicators at the district level in sub-Saharan Africa.

J Int AIDS Soc 2021 Sep;24 Suppl 5:e25788

Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Lilongwe, Malawi.

Introduction: HIV planning requires granular estimates for the number of people living with HIV (PLHIV), antiretroviral treatment (ART) coverage and unmet need, and new HIV infections by district, or equivalent subnational administrative level. We developed a Bayesian small-area estimation model, called Naomi, to estimate these quantities stratified by subnational administrative units, sex, and five-year age groups.

Methods: Small-area regressions for HIV prevalence, ART coverage and HIV incidence were jointly calibrated using subnational household survey data on all three indicators, routine antenatal service delivery data on HIV prevalence and ART coverage among pregnant women, and service delivery data on the number of PLHIV receiving ART. Read More

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September 2021

Updates to the Spectrum/AIM model for the UNAIDS 2020 HIV estimates.

J Int AIDS Soc 2021 Sep;24 Suppl 5:e25778

Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.

Introduction: The Spectrum/AIM model is used by national HIV programs and UNAIDS to prepare annual estimates of key HIV indicators. This article describes key updates to paediatric and adult models for the 2021 round of HIV estimates.

Methods: Potential updates to Spectrum arise due to newly available data, new analyses of existing data, and the need for new issues to be addressed. Read More

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September 2021

Evaluation of Scopio Labs X100 Full Field PBS: The first high-resolution full field viewing of peripheral blood specimens combined with artificial intelligence-based morphological analysis.

Int J Lab Hematol 2021 Sep 21. Epub 2021 Sep 21.

Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

Background: Current digital cell imaging systems perform peripheral blood smear (PBS) analysis in limited regions of the PBS and require the support of manual microscopy without achieving full digital microscopy. We report a multicenter study that validated the Scopio Labs X100 Full Field PBS, a novel digital imaging system that utilizes a full field view approach for cell recognition and classification, in a decision support system mode.

Methods: We analyzed 335 normal and 310 abnormal PBS from patients with various clinical conditions and compared the performance of Scopio's Full Field PBS as the test method, with manual PBS analysis as the reference method. Read More

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September 2021

The estimation of a preference-based single index for the IBS-QoL by mapping to the EQ-5D-5L in patients with irritable bowel syndrome.

Qual Life Res 2021 Sep 21. Epub 2021 Sep 21.

Department of Clinical Epidemiology and Medical Technology Assessment, CAPHRI Care and Public Health Research Institute, Maastricht University Medical Center, Maastricht, The Netherlands.

Purpose: The Irritable Bowel Syndrome Quality of Life (IBS-QoL) questionnaire is a commonly used and validated IBS-specific QoL instrument. However, this questionnaire is in contrast to the EQ-5D-5L, not preference-based and as such does not allow calculation of QALYs. The objective of this study was to describe the convergent- and known-group validity of both questionnaires and to develop a mapping algorithm from EQ-5D-5L which enable IBS-QoL scores to be transformed into utility scores for use in economic evaluations. Read More

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September 2021

Direct determination of molar absorption coefficients of several molecules in the lowest excited singlet states.

Photochem Photobiol Sci 2021 Sep 21. Epub 2021 Sep 21.

Division of Frontier Materials Science and Center for Advanced Interdisciplinary Research, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, 560-8531, Japan.

Molar absorption coefficient of the lowest excited state is an indispensable information for the quantitative investigation of photochemical reactions by means of transient absorption spectroscopy. In the present work, we quantitatively estimated the molar absorption coefficients of the S state of the solute in three solution systems, Rhodamine B in ethanol, ZnTPP in DMF and N,N'-bis(2,6-diisopropylphenyl)terrylene-3,4,11,12-tetracarboxydiimide (TDI) in chloroform, by perfectly bleaching the ground state molecules using the picosecond 532-nm laser pulse with a large number of photons. These solution systems were selected because no obvious photodegradation was detected in the present range of the excitation intensity. Read More

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September 2021

Emotional behavior and brain anatomy of the mdx52 mouse model of Duchenne muscular dystrophy.

Dis Model Mech 2021 Sep 21;14(9). Epub 2021 Sep 21.

Université Paris-Saclay, CNRS, Institut des Neurosciences Paris Saclay, 91190, Gif-sur-Yvette, France.

The exon-52-deleted mdx52 mouse is a critical model of Duchenne muscular dystrophy (DMD), as it features a deletion in a hotspot region of the DMD gene, frequently mutated in patients. Deletion of exon 52 impedes expression of several brain dystrophins (Dp427, Dp260 and Dp140), thus providing a key model for studying the cognitive impairment associated with DMD and testing rescuing strategies. Here, using in vivo magnetic resonance imaging and neurohistology, we found no gross brain abnormalities in mdx52 mice, suggesting that the neural dysfunctions in this model are likely at the level of brain cellular functionalities. Read More

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September 2021

The role of immature platelet count and immature platelet fraction in determining the need for transfusion in patients undergoing CABG.

Cardiovasc J Afr 2021 Sep 20;32:1-5. Epub 2021 Sep 20.

Okmeydani Training and Research Hospital, Istanbul, Turkey.

Background: Platelet dysfunction has been shown to play a role in postoperative bleeding, however it is not clear whether immature platelets (IP) can induce appropriate homeostasis to prevent excessive bleeding in patients undergoing coronary artery bypass grafting (CABG). The aim of this study was to evaluate the postoperative change in IP count (IPC), IP fraction (IPF) and mean platelet volume (MPV), and to examine their relationship with postoperative bleeding and blood transfusion.

Methods: One hundred and forty-nine consecutive patients undergoing elective CABG were included in this prospective study. Read More

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September 2021

Overview, consequences, and strategies for overcoming matrix effects in LC-MS analysis: a critical review.

Analyst 2021 Sep 21. Epub 2021 Sep 21.

Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

The high-performance liquid chromatography-mass spectrometry (LC-MS) technique is widely applied to routine analysis in many matrices. Despite the enormous application of LC/MS, this technique is subjected to drawbacks called matrix effects (MEs) that could lead to ion suppression or ion enhancement. This phenomenon can exert a deleterious impact on the ionization efficacy of an analyte and subsequently on the important method performance parameters. Read More

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September 2021

A Fully Automated Analytic System for Measuring Endolymphatic Hydrops Ratios in Patients With Ménière Disease via Magnetic Resonance Imaging: Deep Learning Model Development Study.

J Med Internet Res 2021 Sep 21;23(9):e29678. Epub 2021 Sep 21.

Department of Medical Device Management and Research, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul, Republic of Korea.

Background: Recently, the analysis of endolymphatic hydropses (EHs) via inner ear magnetic resonance imaging (MRI) for patients with Ménière disease has been attempted in various studies. In addition, artificial intelligence has rapidly been incorporated into the medical field. In our previous studies, an automated algorithm for EH analysis was developed by using a convolutional neural network. Read More

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September 2021

Noninvasive Estimation of Hepatic Steatosis by Controlled Attenuation Parameter in Living Donor Liver Transplant.

Exp Clin Transplant 2021 Sep 20. Epub 2021 Sep 20.

From the Shiraz Transplant Center, Abu-Ali Sina Hospital, Shiraz, Iran.

Objectives: Estimation of liver fat among living donor candidates is necessary before living donor liver transplant. This study aimed to investigate the usefulness of the controlled attenuation parameter compared with liver biopsy for pretransplant estimation of hepatic steatosis in living liver donors.

Materials And Methods: In this retrospective study, we included all individuals who underwent transient elastography with controlled attenuation parameter and ultrasonography-guided liver biopsy as a part of donor evaluations before living donor liver transplant. Read More

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September 2021

Uncertainty in denoising of MRSI using low-rank methods.

Magn Reson Med 2021 Sep 21. Epub 2021 Sep 21.

Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

Purpose: Low-rank denoising of MRSI data results in an apparent increase in spectral SNR. However, it is not clear if this translates to a lower uncertainty in metabolite concentrations after spectroscopic fitting. Estimation of the true uncertainty after denoising is desirable for downstream analysis in spectroscopy. Read More

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September 2021

Training data distribution significantly impacts the estimation of tissue microstructure with machine learning.

Magn Reson Med 2021 Sep 21. Epub 2021 Sep 21.

Centre for Medical Image Computing, Department of Computer Science, University College London, London, UK.

Purpose: Supervised machine learning (ML) provides a compelling alternative to traditional model fitting for parameter mapping in quantitative MRI. The aim of this work is to demonstrate and quantify the effect of different training data distributions on the accuracy and precision of parameter estimates when supervised ML is used for fitting.

Methods: We fit a two- and three-compartment biophysical model to diffusion measurements from in-vivo human brain, as well as simulated diffusion data, using both traditional model fitting and supervised ML. Read More

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September 2021

Estimation of diffuse Cherenkov optical emission from external beam radiation build-up in tissue.

J Biomed Opt 2021 Sep;26(9)

Thayer School of Engineering at Dartmouth, Dartmouth College, United States.

Significance: Optical imaging of Cherenkov emission during radiation therapy could be used to verify dose delivery in real-time if a more comprehensive quantitative understanding of the factors affecting emission intensity could be developed.

Aim: This study aims to explore the change in diffuse Cherenkov emission intensity with x-ray beam energy from irradiated tissue, both theoretically and experimentally.

Approach: Derivation of the emitted Cherenkov signal was achieved using diffusion theory, and experimental studies with 6 to 18 MV energy x-rays were performed in tissue phantoms to confirm the model predictions as related to the radiation build-up factor with depth into tissue. Read More

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September 2021

Hepatic Iron Quantification Using a Free-Breathing 3D Radial Gradient Echo Technique and Validation With a 2D Biopsy-Calibrated R Relaxometry Method.

J Magn Reson Imaging 2021 Sep 20. Epub 2021 Sep 20.

Department of Biomedical Engineering, The University of Memphis, Memphis, Tennessee, USA.

Background: Hepatic iron content (HIC) is an important parameter for the management of iron overload. Non-invasive HIC assessment is often performed using biopsy-calibrated two-dimensional breath-hold Cartesian gradient echo (2D BH GRE) R -MRI. However, breath-holding is not possible in most pediatric patients or those with respiratory problems, and three-dimensional free-breathing radial GRE (3D FB rGRE) has emerged as a viable alternative. Read More

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September 2021

Muscarinic receptor binding activity in rat tissues by vibegron and prediction of its receptor occupancy levels in the human bladder.

Int J Urol 2021 Sep 21. Epub 2021 Sep 21.

Department of Pharmacology II, School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women's University, Nishinomiya, Japan.

Objectives: To examine the effects of vibegron, a selective β -adrenoceptor agonist, used to treat overactive bladder, on muscarinic receptors in the rat bladder, and to predict the occupancy levels of muscarinic receptors by vibegron in the bladders of humans orally administered a clinical dose.

Methods: Muscarinic receptors in the rat bladder and other tissues were examined by a radioligand binding assay using [N-methyl- H]scopolamine chloride. The occupancy levels of muscarinic receptors by vibegron in bladders of humans after its oral administration were predicted from the estimation of unbound concentrations in human plasma and urine in the literature. Read More

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September 2021

Assessing the Kinetics of Metabolite Uptake and Utilization by Isolated Mitochondria Using Selective Reaction Monitoring Mass Spectrometry (SRM-MS).

Methods Mol Biol 2022 ;2363:85-100

ARC Centre of Excellence in Plant Energy Biology, Bayliss Building M316, University of Western Australia, Crawley, WA, Australia.

Transport of tricarboxylic acid (TCA) cycle substrates across mitochondrial membranes and their subsequent oxidative decarboxylation in the matrix provide reductants for respiration-coupled ATP synthesis. These processes are typically assessed together through the ability of mitochondria to consume oxygen or release carbon dioxide, however, this approach fails to assess or separate the complexity of transport and the subsequent metabolism of substrates and products. In this chapter, we provide a strategy for simultaneously measuring substrate transport and utilization by isolated mitochondria using a mass spectrometry-based technique. Read More

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January 2022

Early and Late Neural Correlates of Mentalizing: ALE Meta-Analyses in Adults, Children and Adolescents.

Soc Cogn Affect Neurosci 2021 Sep 21. Epub 2021 Sep 21.

Jacobs Center for Productive Youth Development, University of Zurich, Zurich, Switzerland.

The ability to understand mental states of others is referred to as mentalizing and enabled by our Theory of Mind. This social skill relies on brain regions comprising the mentalizing network, as robustly observed in adults, but also in a growing number of developmental studies. We summarized and compared neuroimaging evidence in children/adolescents and adults during mentalizing using coordinate-based activation likelihood estimation meta-analyses to inform about brain regions consistently or differentially engaged across age categories. Read More

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September 2021

SARS-CoV-2 serology across scales: a framework for unbiased seroprevalence estimation incorporating antibody kinetics and epidemic recency.

medRxiv 2021 Sep 14. Epub 2021 Sep 14.

Serosurveys are a key resource for measuring SARS-CoV-2 cumulative incidence. A growing body of evidence suggests that asymptomatic and mild infections (together making up over 95% of all infections) are associated with lower antibody titers than severe infections. Antibody levels also peak a few weeks after infection and decay gradually. Read More

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September 2021

Estimation of pollutant sources in multi-zone buildings through different deconvolution algorithms.

Build Simul 2021 Sep 10:1-14. Epub 2021 Sep 10.

College of Electrical Engineering and Control Science, Nanjing Tech University, Nanjing, 210009 China.

Effective identification of pollution sources is particularly important for indoor air quality. Accurate estimation of source strength is the basis for source effective identification. This paper proposes an optimization method for the deconvolution process in the source strength inverse calculation. Read More

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September 2021

Image Processing for the Prevention of Infectious Diseases: Determination of Mask Wearing, Measurement of Hand Washing Time, and Disinfection Support System.

New Gener Comput 2021 Sep 16:1-14. Epub 2021 Sep 16.

Lightblue Technology Inc., Tokyo, Japan.

The new coronavirus infection (COVID-19) has spread to numerous countries around the world since several cases of the disease were first reported in late December 2019 in China. Currently, the WHO strongly recommends infection prevention measures such as wearing masks, hand washing, and frequent disinfection of high-touch surfaces, but there were many arguments against infection prevention policy in March 2020. For example, the WHO did not recommend the use of masks for the healthy general public. Read More

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September 2021