Med Sci Sports Exerc 2020 Dec 23;Publish Ahead of Print. Epub 2020 Dec 23.
Health Unit, Flemish Institute for Technological Research (VITO), Mol, Belgium Measure, Model & Manage Bioresponses, Department of Biosystems, KU Leuven, Leuven, Belgium ISGlobal, Barcelona, Spain Universitat Pompeu Fabra (UPF), Barcelona, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium Department of Biology, University of Antwerp, Wilrijk, Belgium Department of Research and Development, CIRO, Horn, The Netherlands School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Centre, Maastricht, The Netherlands Department of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands Ludwig Boltzmann Institute for Lung Health, Vienna, Austria Rehabilitation Research Center (REVAL), Biomedical Research Institute (BIOMED), Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium.
Purpose: Not all patients with chronic obstructive pulmonary disease (COPD) experience similar benefits following pulmonary rehabilitation (PR). This pre-post PR study used a large sample of patients with COPD to determine whether PR-induced changes of oxygen uptake (V[Combining Dot Above]O2) kinetics and exercise responses of V[Combining Dot Above]O2, carbon dioxide output (V[Combining Dot Above]CO2), minute ventilation (V[Combining Dot Above]E), V[Combining Dot Above]E/V[Combining Dot Above]CO2, breathing frequency and tidal volume differed between responders and non-responders to PR.
Methods: Responders to PR were defined as patients with a minimal clinically important increase in endurance time of 105 s. Read More