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A step-by-step approach to endorectal proctopexy (ERPP): how we do it.

Tech Coloproctol 2021 07 28;25(7):879-886. Epub 2021 May 28.

Department of Colorectal Surgery, S. Rita Clinic, Vercelli, Italy.

There are many surgical treatments aimed at correcting internal mucosal prolapse and rectocele associated with obstructed defecation syndrome (ODS). Perineal procedures can be considered as first options in young men in whom an abdominal approach poses risks of sexual dysfunction and in selected women with isolated posterior compartment prolapse who failed conservative treatment. About 20 years ago, we described endorectal proctopexy (ERPP) also known as internal Delorme procedure. Read More

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EndoRectal ProctoPexy (ERPP) for recurrent semi-circumferential rectal polyp.

Tech Coloproctol 2018 03 9;22(3):235-237. Epub 2018 Feb 9.

Department of Colorectal Surgery, S. Rita Clinic, Vercelli, Italy.

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Crystal structures of the Erp protein family members ErpP and ErpC from Borrelia burgdorferi reveal the reason for different affinities for complement regulator factor H.

Biochim Biophys Acta 2015 May 9;1854(5):349-55. Epub 2015 Jan 9.

Latvian Biomedical Research and Study Centre, Ratsupites 1, LV-1067 Riga, Latvia; University of Latvia, Kronvalda bulv. 4, LV-1586, Riga, Latvia.

Borrelia burgdorferi is the causative agent of Lyme disease, which can be acquired after the bite of an infected Ixodes tick. As a strategy to resist the innate immunity and to successfully spread and proliferate, B. burgdorferi expresses a set of outer membrane proteins that are capable of binding complement regulator factor H (CFH), factor H-like protein 1 (CFHL-1) and factor H-related proteins (CFHR) to avoid complement-mediated killing. Read More

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Internal Delorme vs. STARR procedure for correction of obstructed defecation from rectocele and rectal intussusception.

Ann Ital Chir 2014 Mar-Apr;85(2):177-83

Purpose: "Outlet obstruction" is a complex functional disorder compelling patients to exhausting uneffective attempts to void. This study was designed to compare the effectiveness and a safety of the endorectal proctopexy (internal Delorme) vs STARR procedure in two groups of patients.

Methods: A total of 66 patients with rectocele and associated mucosal prolapse or anorectal intussusception between January 2006 and June 2010 were randomly assigned to Group # 1 Endorectal proctopexy with levatorplasty (ERPP) and Group # 2 STARR. Read More

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Consensus views on implementation and measurement of enhanced recovery after surgery in England: Delphi study.

BMJ Open 2012 12;2(6). Epub 2012 Dec 12.

Department of General Surgery, Yeovil District Hospital, Yeovil, UK.

Objective: The Department of Health's Enhanced Recovery Partnership Programme (ERPP) started a spread and adoption scheme of Enhanced Recovery After Surgery (ERAS) throughout England. In preparation for widespread adoption the ERPP wished to obtain expert consensus on appropriate outcome measures for ERAS, emerging techniques being widely adopted and proposed methods for the continued development and sustainability of ERAS in the National Health Service. The aim of this study was to interrogate expert opinion and define areas of consensus on these issues. Read More

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February 2013

The effectiveness of the error reporting promoting program on the nursing error incidence rate in Korean operating rooms.

Taehan Kanho Hakhoe Chi 2007 Mar;37(2):185-91

Department of Nursing, Ulsan College, Ulsan, Korea.

Purpose: The purpose of this study was to develop and evaluate an error reporting promoting program(ERPP) to systematically reduce the incidence rate of nursing errors in operating room.

Methods: A non-equivalent control group non-synchronized design was used. Twenty-six operating room nurses who were in one university hospital in Busan participated in this study. Read More

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Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs.

J Immunol 2002 Oct;169(7):3847-53

Department of Bacteriology and Immunology, Haartman Institute and Helsinki University Central Hospital, and Peptide and Protein Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland.

Borrelia burgdorferi spirochetes can circumvent the vertebrate host's immune system for long periods of time. B. burgdorferi sensu stricto and B. Read More

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October 2002

Enhancement of tumorigenicity and invasion capacity of rat mammary adenocarcinoma cells by epidermal growth factor and transforming growth factor-beta.

Jpn J Cancer Res 1993 Nov;84(11):1145-9

Laboratory of Pathology, Hokkaido University School of Medicine, Sapporo.

We have studied the effects of growth factors and cytokines on the tumorigenicity and invasion capacity of tumor cells by using regressor and progressor tumor cell lines (ER-1 and ERpP, respectively) derived from an SHR rat mammary adenocarcinoma. ER-1 cells regress spontaneously whereas ERpP cells show invasive growth and high metastasis to lung and other organs in syngeneic SHR rats. When ER-1 cells were pretreated with either epidermal growth factor (EGF) or transforming growth factor-beta (TGF-beta) for 24 h in vitro, and intraperitoneally transplanted into SHR rats, they grew and killed the host, whereas ER-1 cells pretreated with tumor necrosis factor-alpha did not. Read More

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November 1993
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