34 results match your criteria erm vaccination


Primary immunization using low antigen dosages and immunological tolerance in rainbow trout.

Fish Shellfish Immunol 2020 Oct 30;105:16-23. Epub 2020 Jun 30.

Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark.

Enteric redmouth disease (ERM), caused by the Gram negative enterobacterium Yersinia ruckeri, affects farming of salmonids, but vaccination against ERM confers a certain degree of protection dependent on the administration route. Recent studies on oral vaccination of rainbow trout suggest that immunological tolerance may be induced by primary immunization using a low antigen dosage. We have examined if low dosages of Y. Read More

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October 2020

Immunity to Hepatitis B is Undetectable in the Majority of Adolescents and Young Adults Seeking Outpatient Medication Treatment for Opioid Use Disorder.

J Addict Med 2020 12;14(6):e359-e361

Department of Biobehavioral Health, The Pennsylvania State University, PA (SWS); Division of Adolescent Medicine, Nationwide Children's Hospital, Columbus, OH (SWS, ERM, SCM, AEB); Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH (ERM, SCM, AEB); Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH (AEB).

Objective: To assess prevalence and predictors of hepatitis B immune status among adolescents and young adults (AYA) seeking outpatient medication treatment for opioid use disorder (MOUD).

Study Design: A retrospective medical chart review was conducted of AYA seeking MOUD between January 1, 2013 through December 31, 2015. Inclusion criteria included: diagnosis of opioid use disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition; received hepatitis serologic testing; and no evidence of prior or current hepatitis B infection. Read More

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December 2020

Effect of oral booster vaccination of rainbow trout against Yersinia ruckeri depends on type of primary immunization.

Fish Shellfish Immunol 2019 Feb 31;85:61-65. Epub 2017 Oct 31.

Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.

Vaccination of rainbow trout against Enteric Redmouth Disease (ERM) caused by Yersinia ruckeri can be successfully performed by administering vaccine (a bacterin consisting of formalin killed bacteria) by immersion, bath or injection. Booster immunization is known to increase the protection of fish already primed by one of these vaccination methods. Oral vaccination of trout (administering vaccine in feed) is an even more convenient way of presenting antigen to the fish but the effect of an oral booster has not previously been described in detail. Read More

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February 2019

Dissecting the immune pathways stimulated following injection vaccination of rainbow trout (Oncorhynchus mykiss) against enteric redmouth disease (ERM).

Fish Shellfish Immunol 2019 Feb 27;85:18-30. Epub 2017 Jul 27.

Scottish Fish Immunology Research Centre, School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, UK. Electronic address:

Enteric redmouth disease (ERM or yersiniosis) is one of the most important diseases of salmonids and leads to significant economic losses. It is caused by the Gram-negative bacterium Yersinia ruckeri but can be controlled by bacterin vaccination. The first commercial ERM vaccine was licenced in 1976 and is one of the most significant and successful health practices within the aquaculture industry. Read More

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February 2019

Secondary immune response of rainbow trout following repeated immersion vaccination.

J Fish Dis 2018 Jan 14;41(1):117-123. Epub 2017 Jul 14.

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.

Teleosts are able to raise a protective immune response, comprising both innate and adaptive elements, against various pathogens. This is the basis for a widespread use of vaccines, administered as injection or immersion, in the aquaculture industry. It has been described that repeated injection vaccination of fish raises a secondary immune response, consisting of rapid, accelerated and increased antibody reaction. Read More

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January 2018

Efficacy testing of 35-year-old commercially produced ERM bacterin reveals the remarkable stability of this product.

J Fish Dis 2017 Dec 26;40(12):1921-1924. Epub 2017 May 26.

Research Division, Clear Springs Foods, Inc., Buhl, ID, USA.

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December 2017

Determination of Characteristics of Erythromycin Resistant Streptococcus pneumoniae with Preferred PCV Usage in Iran.

PLoS One 2016 29;11(12):e0167803. Epub 2016 Dec 29.

Department of Microbiology, Pasteur Institute of Iran, Tehran, Iran.

Amongst 100 Streptococcus pneumoniae isolated from clinical cases and nasopharynx of healthy individuals, 60 erythromycin resistant strains were isolated and characterized using MLST, PFGE, transposon analysis and Quellung reaction. Most of the S. pneumoniae erythromycin resistant (80%) were found to be attributable to the ermB-edncoded ribosome methylase activity which differs from the dominant mechanism of macrolide resistance seen in North America. Read More

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Yersinia ruckeri Isolates Recovered from Diseased Atlantic Salmon (Salmo salar) in Scotland Are More Diverse than Those from Rainbow Trout (Oncorhynchus mykiss) and Represent Distinct Subpopulations.

Appl Environ Microbiol 2016 10 16;82(19):5785-94. Epub 2016 Sep 16.

Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Unlabelled: Yersinia ruckeri is the etiological agent of enteric redmouth (ERM) disease of farmed salmonids. Enteric redmouth disease is traditionally associated with rainbow trout (Oncorhynchus mykiss, Walbaum), but its incidence in Atlantic salmon (Salmo salar) is increasing. Yersinia ruckeri isolates recovered from diseased Atlantic salmon have been poorly characterized, and very little is known about the relationship of the isolates associated with these two species. Read More

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October 2016

Yersinia ruckeri lipopolysaccharide is necessary and sufficient for eliciting a protective immune response in rainbow trout (Oncorhynchus mykiss, Walbaum).

Fish Shellfish Immunol 2016 Feb 4;49:420-6. Epub 2016 Jan 4.

Research Division, Clear Springs Foods, Inc., PO Box 712, Buhl, ID 83316, USA.

Enteric redmouth disease (ERM), caused by Yersinia ruckeri, has been controlled successfully using immersion-applied bacterin vaccines for several decades. While the host response to vaccination and the mechanism of protection of this vaccine have been elucidated, the bacterial components eliciting protection have remained unclear. Here we show that highly purified serotype O1 Y. Read More

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February 2016

Effects of adjuvant Montanide™ ISA 763 A VG in rainbow trout injection vaccinated against Yersinia ruckeri.

Fish Shellfish Immunol 2015 Dec 19;47(2):797-806. Epub 2015 Oct 19.

Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.

Enteric redmouth disease (ERM) caused by the fish pathogen Yersinia ruckeri is a major threat to freshwater production of rainbow trout (Oncorhynchus mykiss) throughout all life stages. Injection vaccination of rainbow trout against Y. ruckeri infection has been shown to confer better protection compared to the traditionally applied immersion vaccination. Read More

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December 2015

Yersinia ruckeri, the causative agent of enteric redmouth disease in fish.

Vet Res 2015 Sep 24;46:103. Epub 2015 Sep 24.

Clinical Division of Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine, Vienna, Austria.

Enteric redmouth disease (ERM) is a serious septicemic bacterial disease of salmonid fish species. It is caused by Yersinia ruckeri, a Gram-negative rod-shaped enterobacterium. It has a wide host range, broad geographical distribution, and causes significant economic losses in the fish aquaculture industry. Read More

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September 2015

Nasal vaccination of young rainbow trout (Oncorhynchus mykiss) against infectious hematopoietic necrosis and enteric red mouth disease.

Dev Comp Immunol 2015 Nov 23;53(1):105-11. Epub 2015 Jun 23.

Mathematics and Statistics, University of New Mexico, Albuquerque, NM, USA.

Determining the earliest age at which farmed fish can be successfully vaccinated is a very important question for fish farmers. Nasal vaccines are novel mucosal vaccines that prevent aquatic infectious diseases of finfish. The present study investigates the ontogeny of the olfactory organ of rainbow trout by histology and aims to establish the earliest age for vaccination against infectious hematopoietic necrosis (IHN) and enteric red mouth (ERM) disease using the nasal route. Read More

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November 2015

Global 3D imaging of Yersinia ruckeri bacterin uptake in rainbow trout fry.

PLoS One 2015 6;10(2):e0117263. Epub 2015 Feb 6.

Research Group of Fish Diseases and Immunology, Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark.

Yersinia ruckeri is the causative agent of enteric redmouth disease (ERM) in rainbow trout, and the first commercially available fish vaccine was an immersion vaccine against ERM consisting of Y. ruckeri bacterin. The ERM immersion vaccine has been successfully used in aquaculture farming of salmonids for more than 35 years. Read More

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January 2016

Evaluation of dual nasal delivery of infectious hematopoietic necrosis virus and enteric red mouth vaccines in rainbow trout (Oncorhynchus mykiss).

Vaccine 2015 Feb 3;33(6):771-6. Epub 2015 Jan 3.

Center for Evolutionary and Theoretical Immunology, Department of Biology, University of New Mexico, Albuquerque, NM, USA. Electronic address:

Farmed fish are susceptible to different infectious disease agents including viruses and bacteria. Thus, multivalent vaccines or vaccination programs against two or more pathogens are valuable tools in aquaculture. Recently, nasal vaccines have been shown to be very effective in rainbow trout. Read More

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February 2015

Oral and anal vaccination confers full protection against enteric redmouth disease (ERM) in rainbow trout.

PLoS One 2014 4;9(4):e93845. Epub 2014 Apr 4.

Research group of Fish Diseases and Immunology, Section of Veterinary Clinical Microbiology, Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

The effect of oral vaccines against bacterial fish diseases has been a topic for debate for decades. Recently both M-like cells and dendritic cells have been discovered in the intestine of rainbow trout. It is therefore likely that antigens reaching the intestine can be taken up and thereby induce immunity in orally vaccinated fish. Read More

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January 2015

Biochemical and molecular characterization of the tegument protein RT10 from Raillietina tetragona.

Authors:
Li Chen Haiyun Li

Parasitol Res 2014 Mar 22;113(3):1239-45. Epub 2014 Jan 22.

Department of Aquiculture, College of Animal Science, South China Agricultural University, 483 Wushan Road, Guangzhou, 510642, People's Republic of China.

Tegument antigens of tapeworm play an important role in modulation of host response and parasite survival. Characterizing appropriate antigens for parasite infection diagnosis and vaccination is rational and could have both economic and epidemiological significance in poultry industry. In the present study, a major protoscolex homologue (named RT10) of Echinococcus and Taenia spp. Read More

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Comparative evaluation of administration methods for a vaccine protecting rainbow trout against Yersinia ruckeri O1 biotype 2 infections.

Vet Immunol Immunopathol 2013 Jul 8;154(1-2):42-7. Epub 2013 Apr 8.

Laboratory of Aquatic Pathobiology, Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Numerous outbreaks of enteric red mouth disease (ERM) caused by Yersinia ruckeri O1 biotype 2 in rainbow trout farms are currently being recorded despite established vaccination procedures against this disease. This could indicate that the currently used application of single immersion vaccination (using a commercial vaccine AquaVac(®) RELERA™) does not provide full protection. We elucidated by a controlled duplicated experiment if different vaccine administration methods can improve level and extent of protection. Read More

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Identification of surrogates of protection against yersiniosis in immersion vaccinated Atlantic salmon.

PLoS One 2012 12;7(7):e40841. Epub 2012 Jul 12.

National Centre for Marine Conservation and Resource Sustainability, University of Tasmania, Tasmania, Australia.

Simple cost-effective bacterins are the earliest and most successfully used commercial vaccines in fish. In particular, those prepared from Yersinia ruckeri have proven effective at controlling Enteric Red Mouth Disease (ERM) and yersiniosis in rainbow trout and Atlantic salmon, respectively. However, the emergence of outbreaks of ERM caused by atypical biotypes of Y. Read More

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January 2013

Antimicrobial susceptibility of Streptococcus pneumoniae isolates from vaccinated and non-vaccinated patients with a clinically confirmed diagnosis of community-acquired pneumonia in Belgium.

Int J Antimicrob Agents 2012 Mar 14;39(3):208-16. Epub 2012 Jan 14.

Pharmacologie cellulaire et moléculaire, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.

We assessed the in vitro susceptibility of Streptococcus pneumoniae isolates from patients with confirmed community-acquired pneumonia (CAP) to β-lactams, macrolides and fluoroquinolones and the association of non-susceptibility and resistance with serotypes/serogroups (STs/SGs), patient's risk factors and vaccination status. Samples (blood or lower respiratory tract) were obtained in 2007-2009 from 249 patients (from seven hospitals in Belgium) with a clinical and radiological diagnosis of CAP [median age 61 years (11.6% aged <5 years); 85% without previous antibiotic therapy; 86% adults with level II Niederman's severity score]. Read More

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Comparative protection of two different commercial vaccines against Yersinia ruckeri serotype O1 and biotype 2 in rainbow trout (Oncorhynchus mykiss).

Vet Immunol Immunopathol 2012 Jan 21;145(1-2):379-85. Epub 2011 Dec 21.

Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Denmark.

Differentially extended specific protection by two commercial vaccines against Yersinia ruckeri serotype O1 biotype 2 was studied following 30s immersion exposure. Rainbow trout were challenged intra-peritoneally (i.p. Read More

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January 2012

Serotype emergence and genotype distribution among macrolide-resistant invasive Streptococcus pneumoniae isolates in the postconjugate vaccine (PCV-7) era.

Antimicrob Agents Chemother 2012 Feb 28;56(2):743-50. Epub 2011 Nov 28.

Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

We conducted population-based surveillance for pneumococcal bacteremia within a 5-county region surrounding Philadelphia from October 2001 through September 2008, the period following introduction of the seven-valent pneumococcal conjugate vaccine. Erythromycin resistance increased from 14.7% in 2001-2002 to 20. Read More

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February 2012

Clonality behind the increase of multidrug-resistance among non-invasive pneumococci in Southern Finland.

Eur J Clin Microbiol Infect Dis 2012 May 26;31(5):867-71. Epub 2011 Aug 26.

Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare, Helsinki and Turku, Finland.

Multidrug-resistance among Streptococcus pneumoniae isolates, especially of serotype 19A, has increased in several countries recently. Even before the introduction of the pneumococcal conjugate vaccine into the Finnish National Vaccination Programme, the proportion of multidrug-resistant (MDR) pneumococci had doubled from 2007 to 2008, when it reached 3.6% in Southern Finland. Read More

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Association between plasma antibody response and protection in rainbow trout Oncorhynchus mykiss immersion vaccinated against Yersinia ruckeri.

PLoS One 2011 24;6(6):e18832. Epub 2011 Jun 24.

Department of Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark.

A key hallmark of the vertebrate adaptive immune system is the generation of antigen-specific antibodies from B cells. Fish are the most primitive gnathostomes (jawed vertebrates) possessing an adaptive immune system. Vaccination of rainbow trout against enteric redmouth disease (ERM) by immersion in Yersinia ruckeri bacterin confers a high degree of protection to the fish. Read More

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November 2011

Gene expression profiling in naïve and vaccinated rainbow trout after Yersinia ruckeri infection: insights into the mechanisms of protection seen in vaccinated fish.

Vaccine 2011 Jun 17;29(26):4388-99. Epub 2011 Apr 17.

Scottish Fish Immunology Research Centre, University of Aberdeen, Institute of Biological and Environmental Sciences, Tillydrone Avenue, Aberdeen AB24 2TZ, Scotland, UK.

Despite the importance and success of vaccination against bacterial diseases in fish, little is known about the mechanisms of vaccine-induced disease resistance. In this study a known efficacious bacterial vaccine, to Enteric Redmouth Disease (ERM), was used to vaccinate rainbow trout, and sixty days later the fish were challenged with the causative agent of the disease, Yersinia ruckeri. The bacterial burden in the spleen, the spleen index, and the expression profiles of pro- and anti-inflammatory cytokines and marker genes for T helper (Th) cells in the spleen and gills were analyzed, in comparison to the profiles in naïve/challenged fish. Read More

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Genotypic and phenotypic characterisation of invasive Streptococcus pneumoniae isolates from Hungary, and coverage of the conjugate vaccines.

J Clin Pathol 2010 Dec 13;63(12):1116-20. Epub 2010 Oct 13.

Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary.

Background And Aims: The 7-valent conjugate pneumococcal vaccine (Prevenar) was introduced as a recommended (but not yet obligatory) vaccine in Hungary in April 2009 and there was a sharp increase in the number of children vaccinated. Hence there is an urgent need for in-depth epidemiological data on invasive pneumococci before vaccination becomes widespread. Such a study has never been done before in Hungary. Read More

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December 2010

The antimicrobial resistance profile of Streptococcus pneumoniae.

Authors:
R R Reinert

Clin Microbiol Infect 2009 Apr;15 Suppl 3:7-11

International Scientific & Clinical Affairs, Vaccines, Wyeth Pharmaceuticals, La Défense, Paris, France.

Antibacterial resistance in pneumococci is increasing worldwide, primarily against beta-lactams and macrolides. Understanding the role played by molecular determinants of resistance, transformation and competence in the evolution of Streptococcus pneumoniae is important in addressing this trend. Data from the Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin (PROTEKT) study indicate that about 40% of pneumococci display multidrug-resistant phenotypes (resistance to three or more antibiotics), with highly variable prevalence rates observed in different countries. Read More

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Antimicrobial susceptibility and molecular epidemiology of Streptococcus pneumoniae isolated from Shanghai, China.

Int J Antimicrob Agents 2008 Nov 23;32(5):386-91. Epub 2008 Aug 23.

Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, China.

In this study, the antimicrobial resistance profiles of pneumococci isolated from respiratory specimens of patients from Shanghai, China, in 2004 and 2005 are described. Non-susceptible rates to penicillin and erythromycin among paediatric isolates (n=122) were 63.1% and 94. Read More

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November 2008

Bath vaccination of rainbow trout (Oncorhynchus mykiss Walbaum) against Yersinia ruckeri: effects of temperature on protection and gene expression.

Vaccine 2008 Feb 10;26(8):1050-62. Epub 2008 Jan 10.

Faculty of Life Sciences, Department of Veterinary Pathobiology, University of Copenhagen, Frederiksberg, Denmark.

Protection of rainbow trout fry following bath vaccination with a bacterin of Y. ruckeri O1, the bacterial pathogen causing enteric red mouth disease (ERM), was investigated at 5, 15 and 25 degrees C. Rainbow trout fry were acclimatised for 8 weeks at the three temperatures before vaccination. Read More

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February 2008

Temperature-dependent expression of immune-relevant genes in rainbow trout following Yersinia ruckeri vaccination.

Dis Aquat Organ 2007 Aug;77(1):41-52

Department of Veterinary Pathobiology, Section of Fish Diseases, Faculty of Life Sciences, The University of Copenhagen, Stigbøjlen 7, 1870 Frederiksberg C., Denmark.

The gene expression of immune-relevant genes in rainbow trout Oncorhynchus mykiss following vaccination with a bacterin of Yersinia ruckeri, a bacterial pathogen causing enteric red mouth disease (ERM), was investigated at 5, 15, and 25 degrees C. Rainbow trout were immunized by i.p. Read More

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First description of non-motile Yersinia ruckeri serovar I strains causing disease in rainbow trout, Oncorhynchus mykiss (Walbaum), cultured in Spain.

J Fish Dis 2006 Jun;29(6):339-46

Department of Microbiology and Ecology, Faculty of Biology, University of Valencia, Valencia, Spain.

Yersinia ruckeri, the causal agent of enteric redmouth (ERM) disease, was isolated from epizootics that occurred in different Spanish rainbow trout, Oncorhynchus mykiss (Walbaum), farms in which vaccination against ERM had been performed. In all episodes, the most pronounced clinical signs exhibited by affected fish were severe haemorrhages in the mouth, eyes and around the vent. The isolates were identified as Y. Read More

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