4,451 results match your criteria epiretinal membranes


A simple new technique for the induction of residual posterior vitreous cortex removal and membrane peeling.

Int J Ophthalmol 2021 18;14(4):622-625. Epub 2021 Apr 18.

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China.

Aim: To describe a quick, cost-effective alternative to using a scraper to remove the residual posterior vitreous cortex and create an inner limiting membrane (ILM) flap during vitrectomy.

Methods: The surgical technique and a retrospective interventional single-center series of cases were described. A hook was made on the tip of a conventional syringe needle (outer diameter, 0. Read More

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Versatility of use of fibrin glue in wound closure and vitreo-retinal surgery.

Int J Retina Vitreous 2021 Apr 15;7(1):33. Epub 2021 Apr 15.

Retina and Vitreus Department, Asociacion para Evitar la Ceguera en México, IAP, Vicente García Torres 46, Col. Barrio San Lucas, Coyoacan, 04030, Mexico City, Mexico.

Background: Fibrin glue is an absorbable blood-derived product, a biological tissue adhesive which imitates the final stages of the coagulation cascade, it produces a firm clot, forming a seal along the whole length of the wound, the resultant fibrin clot degrades physiologically into granulation tissue 2 weeks after the application. Biological glue has been used extensively in many forms of surgical procedures. Its use in eye surgery has grown lately as we have evidence that showed it was effective in securing conjunctival grafts in pterygium surgery, in securing wounds after glaucoma surgery and more importantly in 20G and 23G vitrectomy. Read More

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Surgical outcomes in patients with lamellar macular holes selected based on the optical coherence tomography consensus definition.

Int J Retina Vitreous 2021 Apr 13;7(1):31. Epub 2021 Apr 13.

Ophthalmology Department, AP-HP, Hôpital Lariboisière, Université de Paris, 2 rue Ambroise Paré, 75010, Paris, France.

Purpose: The surgical indication for lamellar macular holes (LMH) is controversial due to a misclassification of different macular diseases. A consensus based on an optical coherence tomography (OCT) definition has recently been suggested. The aim of this study was to investigate the surgical outcomes of patients with LMH selected based on this OCT-based consensus definition. Read More

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Preoperative imaging optimized for epiretinal membrane surgery.

Int J Retina Vitreous 2021 Apr 13;7(1):32. Epub 2021 Apr 13.

Ophthalmology Department, AP-HP, Hôpital Lariboisière, Université de Paris, 75010, Paris, France.

Background: To compare imaging modalities for visualizing primary epiretinal membrane (ERM) with each other and with intraoperative digital images (IDI) after blue staining.

Methods: The records of consecutive patients operated for primary ERM over a 12-month period were retrospectively reviewed. Preoperative imaging included color fundus photography (CFP), En Face spectral-domain optical coherence tomography (OCT), 45° infrared- (IR) and blue-reflectance (BR) scanning laser ophthalmoscopy. Read More

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A prospective randomized clinical trial comparing nepafenac, intravitreal triamcinolone and no adjuvant therapy for epiretinal membrane.

Acta Ophthalmol 2021 Apr 12. Epub 2021 Apr 12.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.

Purpose: To compare the efficacy of topical nepafenac 0.1% versus intravitreal triamcinolone acetonide (IVTA) at the conclusion of vitrectomy surgery versus no adjuvant therapy (NAT) in improving macular morphology post-operatively in patients undergoing vitrectomy for epiretinal membrane (ERM), as measured by optical coherence tomography (OCT) imaging and best-corrected visual acuity (BCVA).

Methods: Design: Prospective randomized clinical trial Setting: Multi-centre 80 patients scheduled to undergo vitrectomy surgery for idiopathic ERM were randomized to receive either IVTA (4 mg/0. Read More

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Multimodal imaging characteristics in eyes with vitreoretinal lymphoma treated with intravitreal rituximab.

Int Ophthalmol 2021 Apr 8. Epub 2021 Apr 8.

Medical Research Foundation, Shri Bhagwan Mahavir Vitreo-Retinal Services, Sankara Nethralaya, 18 College Road, Chennai, 600006, Tamilnadu, India.

Purpose: To characterize the imaging features in eyes with vitreoretinal lymphoma (VRL) using ultra-widefield fundus photography (UWF-FP), swept-source optical coherence tomography (SSOCT) and fundus autofluorescence (FAF) that are correlated to ongoing treatment with intravitreal Rituximab(IVR).

Methods: Retrospective observational imaging-based study of 15 treatment-naive eyes with VRL treated with IVR. All patients with primary VRL underwent vitreous biopsy using 23/25G microincision vitrectomy system for confirmation of diagnosis. Read More

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Rapid Morphological Restoration of Normal Foveal Contour After Spontaneous Epiretinal Membrane Separation from Retina in Eye with Macular Pseudohole: A Case Report.

Int Med Case Rep J 2021 31;14:211-214. Epub 2021 Mar 31.

Department of Ophthalmology, Akita University Graduate School of Medicine, Akita, Japan.

Purpose: This study aims to report a case of idiopathic epiretinal membrane (ERM) spontaneously separated from the retinal surface even in eyes with a macular pseudohole, which was immediately followed by resolution of visual deterioration and morphological findings.

Case Report: A 66-year-old man presented with visual deterioration and metamorphopsia in the right eye. An ERM with a macular pseudohole in the right eye was shown by fundus examinations and optical coherence tomography (OCT) images. Read More

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Recurrent macular hole retinal detachment in a patient with pathologic myopia treated by additional intravitreal silicone oil injection: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25465

Department of Ophthalmology, Keimyung University School of Medicine, Daegu, Republic of Korea.

Rationale: Treatment of macular hole retinal detachment (MHRD) in patients with pathologic myopia may require multiple surgeries due to the risk of surgical failures or recurrences. Intravitreal silicone oil injection before an additional surgery may be another option for recurrent MHRD in aphakic eyes, but this procedure is rarely performed.

Patient Concerns: A 69-year-old man visited the hospital with a chief complaint of metamorphopsia in his right eye for 5 days. Read More

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Clinical update on metamorphopsia: epidemiology, diagnosis and imaging.

Curr Eye Res 2021 Apr 7. Epub 2021 Apr 7.

NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom.

Purpose: To discuss the pathophysiology of metamorphopsia, its characterisation using retinal imaging and methods of assessment of patient symptoms and visual function.

Methods: A literature search of electronic databases was performedResults: Metamorphopsia has commonly been associated with vitreomacular interface disorders (such as epiretinal membrane) and has also regularly been noted in diseases of the retina and choroid, particularly age-related macular degeneration and central serous chorioretinopathy. Developments in optical coherence tomography retinal imaging have enabled improved imaging of the foveal microstructure and have led to the localisation of the pathophysiology of metamorphopsia within the retinal layers of the macula. Read More

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The Effect of the Idiopathic Epiretinal Membrane and Surgically Induced Posterior Vitreous Detachment on the Retinal Nerve Fiber Layer.

Authors:
A Altun

J Ophthalmol 2020 18;2020:5217645. Epub 2020 Nov 18.

Bahçeşehir University, Department of Ophthalmology, Istanbul, Turkey.

Aim: To investigate the changes in the retinal nerve fiber layer (RNFL) following pars plana vitrectomy (PPV) with surgically induced posterior vitreous detachment (PVD) and idiopathic epiretinal membrane (ERM) and internal limiting membrane (ILM) peeling.

Methods: Patients with unilateral ERM with vitreomacular traction were included in this prospective, randomized, and controlled clinical trial. The control group (Group 1) was formed with the nonoperated fellow eyes of the patients, and the study group (Group 2) was formed with the eyes that underwent PPV including idiopathic ERM and ILM peeling. Read More

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November 2020

The Role of OCT Angiography in the Assessment of Epiretinal Macular Membrane.

J Ophthalmol 2021 24;2021:8866407. Epub 2021 Mar 24.

Department of Neurosciences, Psychology, Drug Research and Child Health Eye Clinic, University of Florence, AOU Careggi, Florence 50139, Italy.

Background: The aim of this observational study is to assess pre- and postoperative retinochoroidal vascular changes in patients undergoing epiretinal macular membrane (ERM) surgery by using optical coherence tomography angiography (OCTA).

Materials And Methods: 23 eyes affected by ERM and those which underwent phacovitrectomy associated with ERM peeling were enrolled. They were evaluated using structural OCT and OCTA before surgery and at 1, 3, and 6 months postoperatively. Read More

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Vital dyes in macular hole surgery.

Exp Ther Med 2021 May 22;21(5):527. Epub 2021 Mar 22.

Department of Ophthalmology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

Currently, surgical techniques, such as internal limiting membrane peeling, are used widely for macular holes, macular puckers, epiretinal membranes, diabetic macular edema, retinal detachment, retinal vein occlusions, vitreomacular traction, optic pit maculopathy, and Terson syndrome. This study aimed to highlight any differences regarding visual acuity and ocular tomography coherence changes after staining the internal limiting membrane with dilutions of Brilliant Blue G vs. lutein/zeaxanthin-based dyes. Read More

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Epiretinal Membrane Surgery After Retinal Detachment Repair: Visual Acuity Outcomes and Optical Coherence Tomography Analysis.

Ophthalmol Retina 2021 Mar 29. Epub 2021 Mar 29.

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Purpose: To assess visual acuity (VA) outcomes of epiretinal membrane (ERM) surgery following primary rhegmatogenous retinal detachment (RD) repair.

Design: Retrospective, consecutive case series.

Subjects: Eyes undergoing pars plana vitrectomy (PPV) with membrane peel (MP) surgery for ERM following primary RD repair (PPV with or without scleral buckle (SB) and gas tamponade). Read More

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Clinical and Optical Coherence Tomography Analysis of Intraretinal Microcysts in Patients with Epiretinal Membrane.

Semin Ophthalmol 2021 Apr 1:1-7. Epub 2021 Apr 1.

Department of Ophthalmology; Kahramanmaraş Sütçü Imam University School of Medicine, Kahramanmaraş, Turkey.

: To perform clinical and optical coherence tomography analysis of intraretinal microcysts (IRM) in patients undergoing pars plana vitrectomy (PPV) for primary epiretinal membrane (ERM) treatment. The files of 137 patients who were operated on by a single surgeon for primary epiretinal membrane treatment in our clinic between September 2017 and January 2020 were retrospectively reviewed. Patients with ERM due to secondary pathology were excluded from the study. Read More

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Development and evaluation of a deep learning model for the detection of multiple fundus diseases based on colour fundus photography.

Br J Ophthalmol 2021 Mar 30. Epub 2021 Mar 30.

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China

Aim: To explore and evaluate an appropriate deep learning system (DLS) for the detection of 12 major fundus diseases using colour fundus photography.

Methods: Diagnostic performance of a DLS was tested on the detection of normal fundus and 12 major fundus diseases including referable diabetic retinopathy, pathologic myopic retinal degeneration, retinal vein occlusion, retinitis pigmentosa, retinal detachment, wet and dry age-related macular degeneration, epiretinal membrane, macula hole, possible glaucomatous optic neuropathy, papilledema and optic nerve atrophy. The DLS was developed with 56 738 images and tested with 8176 images from one internal test set and two external test sets. Read More

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Patterns of ellipsoid zone change associated with visual outcome for diabetic macular oedema.

Clin Exp Optom 2021 Mar 29:1-7. Epub 2021 Mar 29.

Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

: Optical coherence tomography biomarkers are dynamic and possibly change over time. The dynamic biomarkers may better predict improvement of final vision than those at baseline for diabetic macular oedema after treatment.: To investigate predictors for ellipsoid zone (EZ) dynamics and the association with visual acuity after treatment for diabetic macular oedema: A total of 135 eyes from 135 patients with anti-vascular endothelial growth factor treatment for diabetic macular oedema were retrospectively enrolled in this study. Read More

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Optical Coherence Tomography Biomarkers in Bilateral Diabetic Macular Edema Patients with Asymmetric anti-VEGF Response.

Semin Ophthalmol 2021 Mar 29:1-8. Epub 2021 Mar 29.

Medicine, Department of Ophthalmology, Izmir Katip Celebi University, Izmir, Turkey.

: This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular edema (DME) Bilateral DME patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab/aflibercept) treatment were retrospectively studied. The morphologic response criterion was central subfield thickness (CST) ≤300 µm; asymmetric response was defined as ≥10% difference in CST reduction between the eyes. The functional response criterion was an increase in logMAR acuity of ≥3 lines, with an increase below this threshold in the fellow eye considered asymmetric response. Read More

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Identification and Characterization of Epivascular Glia using En Face OCT.

Am J Ophthalmol 2021 Mar 24. Epub 2021 Mar 24.

Retinal Disorders and Ophthalmic Genetics, Stein Eye Institute, University of California, Los Angeles, Los Angeles, CA; Greater Los Angeles VA Healthcare Center, Los Angeles, CA. Electronic address:

Purpose: To describe the clinical features of epivascular glia (EVG) using en face optical coherence tomography (OCT).

Design: Retrospective cross-sectional study.

Methods: Single institution en face OCT images were reviewed. Read More

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The extracellular matrix complexity of idiopathic epiretinal membranes and the bilaminar arrangement of the associated internal limiting membrane in the posterior retina.

Graefes Arch Clin Exp Ophthalmol 2021 Mar 24. Epub 2021 Mar 24.

Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.

Purpose: To study the composition of the internal limiting membrane (ILM) of the retina, the extracellular matrix (ECM) of idiopathic epiretinal membranes (iERMs), and the relationships occurring between the two membranes.

Methods: Forty-six iERMs, 24 of them associated with the ILM, were collected and included in this study. The investigation has been carried out by immunofluorescence and confocal microscopy on glutaraldehyde- and osmium-fixed epon-embedded samples and on frozen samples. Read More

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Surgery for idiopathic epiretinal membrane.

Cochrane Database Syst Rev 2021 03 24;3:CD013297. Epub 2021 Mar 24.

UCL Institute of Ophthalmology, London, UK.

Background: Epiretinal membrane is an abnormal sheet of avascular fibrocellular tissue that develops on the inner surface of the retina. Epiretinal membrane can cause impairment of sight as a consequence of progressive distortion of retinal architecture.

Objectives: To determine the effects of surgery compared to no intervention for epiretinal membrane. Read More

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Prediction of Visual Prognosis after Epiretinal Membrane Surgery Using Regression Tree Analysis.

Semin Ophthalmol 2021 Mar 18:1-6. Epub 2021 Mar 18.

Hayashi Eye Hospital, Fukuoka, Japan.

: Confounding factors should be considered when predicting visual prognosis after epiretinal membrane (ERM) surgery. We aimed to predict visual acuity after ERM surgery using regression tree analysis.: We retrospectively reviewed 343 eyes of 343 patients who underwent vitrectomy for idiopathic ERM. Read More

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Comparison of Anatomical and Functional Results of Surgeries Performed with Nitinol Flex Loop or Forceps in Primary Epiretinal Membrane.

Semin Ophthalmol 2021 Mar 18:1-10. Epub 2021 Mar 18.

Department of Ophthalmology, Kayserı City Training and Research Hospital, Kocasinan, Kayseri, TURKEY.

: To compare surgery's effect with nitinol flex loop (NFL) or forceps on retinal layers and functional outcomes in the primary epiretinal membrane (ERM).: The operations were classified according to the use of the NFL or forceps. Automatic segmentation of the individual inner retinal layers was performed by spectral-domain optical coherence tomography software, and best-corrected visual acuity (BCVA) before surgery and at the last follow-up visit postoperatively were compared. Read More

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Modified surgical technique for lamellar macular holes with lamellar hole-associated epiretinal proliferation (LHEP).

Int Ophthalmol 2021 Mar 17. Epub 2021 Mar 17.

Vitreo-Retina Consultant, DISHA Eye Hospital, 88(63A), Ghoshpara Road, Barrackpore, Kolkata, 700120, West Bengal, India.

Purpose: To evaluate the efficacy and safety of lamellar hole-associated epiretinal proliferation embedding technique with modification in the surgical management of degenerative lamellar macular hole (LMH).

Methods: There is retrospective case series of consecutive eyes who underwent pars plana vitrectomy with LHEP embedding with internal limiting membrane (ILM) inversion technique for degenerative LMH. Primary outcome measure was improvement in foveal contour and central foveal thickness (CFT). Read More

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A novel quantitative analysis method for idiopathic epiretinal membrane.

PLoS One 2021 17;16(3):e0247192. Epub 2021 Mar 17.

Department of Biomedical Sciences, Humanitas University, Milan, Italy.

Purpose: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole.

Methods: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. Read More

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Outcomes after Descemet membrane endothelial keratoplasty over a period of 7 years at a tertiary referral center: endothelial cell density, central corneal thickness, and visual acuity.

Graefes Arch Clin Exp Ophthalmol 2021 Mar 15. Epub 2021 Mar 15.

Department of Ophthalmology, University Hospital of Tübingen, Tübingen, Baden-Württemberg, Germany.

Purpose: To better assess clinical trajectories of patients with or without ocular comorbidity after Descemet membrane endothelial keratoplasty.

Background: To report on the outcomes of eyes with differing starting conditions following surgery.

Design: Retrospective study at a University Eye Hospital. Read More

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Risk of Cataract in Intermediate Uveitis.

Am J Ophthalmol 2021 Mar 10. Epub 2021 Mar 10.

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA; Department of Ophthalmology, Harvard Medical School, Boston, MA; Department of Ophthalmology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; MCM Eye Unit; MyungSung Christian Medical Center (MCM General Hospital) and MyungSung Medical School, Addis Ababa, Ethiopia. Electronic address:

Purpose: To determine the incidence of and predictive factors for cataract in intermediate uveitis.

Design: Retrospective cohort study METHODS: Patients were identified from the Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study, in which medical records were reviewed to determine demographic and clinical data of every eye/patient at every visit at five participating United States tertiary care uveitis centers. The primary outcome was development of vision-compromising cataract as defined by a decrease in visual acuity to 20/40 or less, or requiring cataract surgery. Read More

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Assessment of epiretinal membrane formation using en face optical coherence tomography after rhegmatogenous retinal detachment repair.

Graefes Arch Clin Exp Ophthalmol 2021 Mar 12. Epub 2021 Mar 12.

Department of Ophthalmology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama, 700-8558, Japan.

Purpose: To investigate epiretinal membrane (ERM) formation using en face optical coherence tomography (OCT) after vitrectomy for rhegmatogenous retinal detachment (RRD).

Methods: We retrospectively reviewed the medical records of 64 consecutive eyes (64 patients) with RRD treated by vitrectomy without ERM and internal limiting membrane peeling. ERMs and retinal folds were detected by B-scan and en face imaging. Read More

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[Optical coherence tomography biomarkers in epimacular membranes and vitreomacular traction syndrome].

Ophthalmologe 2021 Apr 10;118(4):308-319. Epub 2021 Mar 10.

 Augen- und Poliklinik, Technische Universität München, München, Deutschland.

Using high-resolution imaging, such as optical coherence tomography (OCT), the different layers of the retina as well as the vitreoretinal interface and its alterations can be very clearly differentiated. This includes the morphological characteristics of tractive maculopathies, such as epiretinal gliosis and vitreomacular traction syndrome. Additionally, structural alterations of the various layers of the neurosensory retina as a result of traction due to these pathologies can be demarcated. Read More

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Functional recovery after macula involving retinal detachment and its correlation with preoperative biomarkers in optical coherence tomography.

Graefes Arch Clin Exp Ophthalmol 2021 Mar 6. Epub 2021 Mar 6.

Klinik und Poliklinik für Augenheilkunde, Technische Universität München, Munich, Germany.

To introduce an ETDRS grid-based classification for macula involving retinal detachment (MIRD) with or without center (foveal) involvement and to identify biomarkers in preoperative optical coherence tomography (OCT) associated with a favorable postoperative functional outcome in eyes with center involving retinal detachment (CIRD). One hundred and two eyes of 102 consecutive patients (f/m: 35/67) with primary rhegmatogenous retinal detachment, preoperative evidence of MIRD (perifoveal involvement of ≤ 6.0 mm), and successful retinal surgery were included in this retrospective cohort study. Read More

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Expression of Lymphatic Markers in the Berger's Space and Bursa Premacularis.

Int J Mol Sci 2021 Feb 19;22(4). Epub 2021 Feb 19.

Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-City 569-8686, Osaka, Japan.

We previously reported that the bursa premacularis (BPM), a peculiar vitreous structure located above the macula, contains numerous cells expressing markers of lymphatic endothelial cells, such as podoplanin and LYVE-1. Herein, we examined the expression of lymphatic markers in the Berger's space (BS), BPM, and vitreous core (VC). BS, BPM, and VC specimens were selectively collected in macular hole and epiretinal membrane patients during vitrectomy and were then immunostained with antibodies for podoplanin, LYVE-1, and fibrillin-1 and -2. Read More

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February 2021