373 results match your criteria epilepticus head


Early and late-onset nonconvulsive status epilepticus after stroke.

Arq Neuropsiquiatr 2021 05;79(5):384-389

Antalya Education and Research Hospital, Department of Neurology, Antalya, Turkey.

Background: Nonconvulsive status epilepticus (NCSE) is a condition that needs timely diagnosis and treatment. It has insignificant clinical features and presents high risk of misdiagnosis.

Objective: To investigate NCSE among patients with stroke, given that stroke plays an important role in the etiology of NCSE. Read More

View Article and Full-Text PDF

Status Triphasicus Versus Status Epilepticus?

J Clin Neurophysiol 2021 Jun 18. Epub 2021 Jun 18.

Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, U.S.A.; and Neurology Services, University of Miami Hospital and Clinics and Jackson Memorial Hospital, Miami, Florida, U.S.A.

Summary: Generalized periodic patterns with triphasic wave morphology, long referred to as triphasic waves [TWs], had been associated with metabolic encephalopathies, although other neurologic and systemic causes have since been identified. In a recent classification of periodic patterns, TWs were formally grouped with the generalized periodic discharges, which are often associated with ictal activity. The interpretation of generalized periodic patterns with TWs as nonictal can have significant implications in the management of comatose patients in nonconvulsive status epilepticus. Read More

View Article and Full-Text PDF

Case Report: A Case of Eyelid Myoclonic Status With Tonic-Clonic Seizure and Literature Review.

Front Pediatr 2021 22;9:671732. Epub 2021 Apr 22.

Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.

Eyelid myoclonus with or without absence epilepsy is a rare and usually misdiagnosed disease in the neurology department. It is an idiopathic general epileptic syndrome, the onset period is 6-8 years, and is more common in girls. It is characterized by rapid abnormal eye blinking, accompanied by upward rolling of the eye and slight backward movement of the head, with eye closure sensitivity and photosensitivity. Read More

View Article and Full-Text PDF

Status epilepticus and diabetes ketoacidosis: uncommon clinical presentations of acromegaly.

Endocrinol Diabetes Metab Case Rep 2021 Apr 1;2021. Epub 2021 Apr 1.

Department of Internal Medicine, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Summary: Acromegaly is a rare disease caused by hypersecretion of the growth hormone (GH). Most cases are caused by either pituitary microadenoma or macroadenoma. The GH producing tumors present with clinical manifestations of acromegaly due to excessive GH secretion or symptoms resulting from mass effects of the enlarging tumor. Read More

View Article and Full-Text PDF

Successful treatment of epilepsia partialis continua with perampanel: two pediatric cases.

Epileptic Disord 2021 Apr;23(2):385-391

Department of Pediatric Neurology, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

Epilepsia partialis continua (EPC) is a form of focal motor status epilepticus, associated with multiple etiologies. Etiology-specific treatments, such as hemispherotomy for Rasmussen encephalitis, lesionectomy for focal cortical dysplasia, and metabolic correction for non-ketotic hyperglycemia, have proven to be efficacious in treating EPC, but, in general, EPC is difficult to treat and often drug-resistant, and there is little evidence to guide therapy. We report the successful treatment of EPC with perampanel in two pediatric patients. Read More

View Article and Full-Text PDF

Sporadic Creutzfeldt-Jakob disease presenting as epilepsia partialis continua and non-ictal nystagmus.

Eur J Neurol 2021 Jul;28(7):2456-2459

Neurology Department, Coimbra University and Hospital Centre, Coimbra, Portugal.

Background And Purpose: Creutzfeldt-Jakob disease (CJD) is a rare form of rapidly progressive neurodegenerative disorder. Seizures are uncommon in the early stage of CJD, increasing diagnostic difficulty.

Methods: An autopsy-proven case of CJD presenting initially as an epilepsia partialis continua is reported, in which the initial workup was unremarkable. Read More

View Article and Full-Text PDF

Radiological manifestation of familial acute necrotizing encephalopathy with RANBP2 mutation in a Far-East Asian family: Case report.

Medicine (Baltimore) 2021 Mar;100(12):e25171

Department of Pediatrics, Pusan National University Children's Hospital, Pusan National University School of Medicine, Yangsan, Korea.

Rationale: Acute necrotizing encephalopathy (ANE) is a specific type of encephalopathy usually followed by febrile infection. It has an aggressive clinical course; however, it usually does not recur after recovery in cases of spontaneous ANE. Nevertheless, there are several studies reporting recurrences in familial ANE with RAN-binding protein 2 (RANBP2) mutation. Read More

View Article and Full-Text PDF

[Nonconvulsive Status Epilepticus Associated with Theophylline: A Case Report].

Brain Nerve 2021 Mar;73(3):283-288

Department of Stroke Medicine, Kawasaki Medical School, General Medical Center.

An 87-year-old woman was admitted to our hospital because of speech disturbance and right facio-pharyngo-glosso-masticatory diplegia. She had bronchial asthma, was previously diagnosed with cerebral infarction, had experienced two events of convulsive status epilepticus, and was undergoing treatment with theophylline, levetiracetam, and clopidogrel. Head diffusion-weighted magnetic resonance imaging revealed a high-signal area in the left crus posterior capsula interna. Read More

View Article and Full-Text PDF

New Onset Non-Convulsive Status Epilepticus Despite Cefepime Renal Dose Adjustment.

Cureus 2021 Jan 13;13(1):e12689. Epub 2021 Jan 13.

Neurology, SSM Health St. Mary's Hospital, St. Louis, USA.

Cefepime, a widely used fourth-generation cephalosporin for coverage of both gram-positive and gram-negative bacteria, has been reported to have associated neurological adverse effects. These effects have been seen mostly in patients mostly with impaired renal function, and currently, dosing is based on creatinine clearance to reduce its toxic effect profile. Despite renal dose adjustment, we present a case of a 40-year-old woman who was managed for bacteremia, acute kidney injury, and hemorrhagic shock. Read More

View Article and Full-Text PDF
January 2021

Fluctuation of Clinical Signs With Near-Syncopal Episodes in a Dog With Gliomatosis Cerebri: A Diagnostic Challenge.

Top Companion Anim Med 2021 Jun 9;43:100508. Epub 2021 Jan 9.

University of Melbourne, Werribee Victoria, Australia.

A 2-year-old Bull Mastiff cross Boxer neutered male dog was evaluated because of 2-month history of non-progressive right head tilt and mild vestibular ataxia. MRI of the brain revealed a faint T2W, FLAIR, DWI and ADC heterogenous hyperintense and T1W isointense intra-axial lesion with indistinct margins at the level of the pons and medulla oblongata. The lesion did not show any susceptibility artefact on T2* GRE images or contrast enhancement and CSF analysis was normal. Read More

View Article and Full-Text PDF

Acute encephalopathy in children with tuberous sclerosis complex.

Orphanet J Rare Dis 2021 01 6;16(1). Epub 2021 Jan 6.

Department of Pediatrics, Aichi Medical University, 1-1 Yazako Karimata, Nagakute, Aichi, 480-1195, Japan.

Objective: We examined the clinical manifestations of acute encephalopathy (AE) and identify risk factors for AE in children with tuberous sclerosis complex (TSC).

Methods: The clinical data of 11 children with clinically diagnosed TSC associated with AE and 109 children with clinically diagnosed TSC alone aged 4 years or older were collected from 13 hospitals.

Results: Of the 11 children with AE, 5 had histories of febrile seizures (FS), and all had histories of febrile status epilepticus (FSE). Read More

View Article and Full-Text PDF
January 2021

Complications and Sequelae in Patients With Congenital Microcephaly Associated With Zika Virus Infection: Two-Year Follow-Up.

J Child Neurol 2021 Jun 7;36(7):537-544. Epub 2021 Jan 7.

28125Universidade Federal do Rio de Janeiro, v. Pedro Calmon, Rio de Janeiro, Brazil.

Background: We aim to describe the long term follow-up of a cohort of children exposed in utero to the Zika virus.

Methods: Descriptive study of a cohort of microcephalic children due to Zika virus. Logistic regression was used to evaluate variables associated with worse prognosis epilepsy. Read More

View Article and Full-Text PDF

The Role of Tourniquet Placement in Management of a Patient With Status Epilepticus.

J Emerg Med 2021 May 24;60(5):607-609. Epub 2020 Dec 24.

Department of Emergency Medicine, Augusta University Health and Medical College of Georgia, Augusta, Georgia.

Background: The global burden of seizure disorders is apparent and necessitates the effective management of patients with status epilepticus (SE). The goal of management is universally accepted as the prompt mitigation of seizure activity with appropriate supportive care. During management, patients may require intubation. Read More

View Article and Full-Text PDF

Temporal subcortical T2 hypointensity on MRI in epilepsia partialis continua, a non ketotic hyperglycemia rather than herpes encephalitis.

Int J Neurosci 2020 Dec 8:1-3. Epub 2020 Dec 8.

Physiotherapy Department, Tarbiat Modares University, Tehran, Iran.

Purpose: Hyperglycemia can present as many neurological problems, one of them is seizure. Different brain MRI features can be seen in focal seizures associated with nonketotic hyperglycemia that subcortical T2 hypointensity is the only characteristic one. Finding this MRI feature is highly valuable in early diagnosis and treatment. Read More

View Article and Full-Text PDF
December 2020

"Neurological manifestations of COVID-19" - guideline of the German society of neurology.

Neurol Res Pract 2020 2;2:51. Epub 2020 Dec 2.

Interdisciplinary Center for Smelling and Tasting, University ENT Hospital Dresden, German Society for ENT Medicine, Dresden, Germany.

Infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to a previously unknown clinical picture, which is known as COVID-19 (COrona VIrus Disease-2019) and was first described in the Hubei region of China. The SARS-CoV-2 pandemic has implications for all areas of medicine. It directly and indirectly affects the care of neurological diseases. Read More

View Article and Full-Text PDF
December 2020

Creutzfeldt-Jakob Disease With Atypical Magnetic Resonance Imaging Features.

Cureus 2020 Nov 2;12(11):e11294. Epub 2020 Nov 2.

Internal Medicine, University at Buffalo - Sisters of Charity Hospital, Buffalo, USA.

Creutzfeld-Jakob disease (CJD) is a rare neurodegenerative condition characterized by rapid progression and fatal outcomes. Patients with progressive dementia and associated atypical features should be investigated, especially with the MRI brain for CJD. Cortical ribboning on diffusion-weighted MRI images is a very crucial diagnostic sign for CJD. Read More

View Article and Full-Text PDF
November 2020

Development and Considerations for Virtual Reality Simulations for Resuscitation Training and Stress Inoculation.

Simul Healthc 2020 Dec 2. Epub 2020 Dec 2.

From the Division of Emergency Medicine, Keck School of Medicine, University of Southern California (T.P.C.), and Division of Emergency and Transport Medicine (T.H.), Children's Hospital Los Angeles, Los Angeles, CA; A.i.Solve, Ltd (T.D.), Luton, United Kingdom; and PM Pediatrics (J.M.S.), Los Angeles, CA.

Introduction: Resuscitation simulations immerse learners into the complexity of emergency patient management. Head-Mounted Display Virtual Reality (VR) has been used for stress inoculation therapy for phobias and posttraumatic stress disorder. However, VR for stress inoculation in resuscitation leadership training has not been studied. Read More

View Article and Full-Text PDF
December 2020

Clinical features and outcomes of nonconvulsive status epilepticus in a developing country: A 5-year retrospective study.

Epilepsy Behav 2020 12 24;113:107547. Epub 2020 Nov 24.

Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines; Electroencephalography Unit, Department of Neurosciences, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.

Background: This study aimed to determine the frequency of electrographically confirmed nonconvulsive status epilepticus (NCSE) in a cohort suspected with this condition and to determine the demographic/clinical profile, treatment, and outcomes of these patients in the context of a developing country, the Philippines.

Methods: We conducted a retrospective study among patients with suspected with NCSE admitted in the Philippine General Hospital from 2014 to 2019. Using the Salzberg 2013 criteria to diagnose NCSE, three electroencephalographers independently reviewed the electroencephalogram (EEG) tracings of suspected patients and were blinded from the clinical information. Read More

View Article and Full-Text PDF
December 2020

Can Neuron Specific Enolase Be a Diagnostic Biomarker for Neuronal Injury in COVID-19?

Cureus 2020 Oct 19;12(10):e11033. Epub 2020 Oct 19.

Clinical Sciences, University of Central Florida College of Medicine, Orlando, USA.

Neuron specific enolase (NSE) is a biomarker for neuronal injury. However, increased levels in cerebrospinal fluid (CSF) and serum is associated with the clinical outcome in patients with head injury, ischemic stroke, intracerebral hemorrhage, cardiac arrest, anoxic encephalopathy, encephalitis, brain metastasis, and status epilepticus. Recently, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which started in China, rapidly evolved into the coronavirus disease 2019 (COVID-19) pandemic. Read More

View Article and Full-Text PDF
October 2020

[Surgical Case of Accidental Infantile Acute Subdural Hematoma Caused by Household Minor Head Trauma:Hyperperfusion during Postoperative Hemispheric Hypodensity, Namely "Big Black Brain"].

No Shinkei Geka 2020 Sep;48(9):841-847

Department of Neurosurgery, Nagano Red Cross Hospital.

We experienced a case of an accidental infantile acute subdural hematoma caused by household minor head trauma(Nakamura type I intracranial hemorrhage)with postoperative hemispheric hypodensity lesion(Big Black Brain)whose pathophysiology was analyzed using perfusion MRI. A ten-month-old boy was admitted to our hospital in a comatose state. His mother revealed that the boy suffered a fall from a sofa bed. Read More

View Article and Full-Text PDF
September 2020

Age-Dependent Reduction in Severity and Discrete Topographical Patterns in Rasmussen Encephalitis: A Link to Cortical Maturation?

Pediatr Neurol 2020 11 11;112:25-33. Epub 2020 Aug 11.

Professor of Neuropathology and Head, General Pathology, Department of General Pathology, Christian Medical College, Vellore, India.

Background: Autopsy studies in Rasmussen encephalitis reveal areas of sparing within the affected hemisphere. Clinical progression and inflammation are milder with an older onset. We sought to demonstrate radiological corroboration for these patterns. Read More

View Article and Full-Text PDF
November 2020

Electrical status epilepticus during sleep in patients with congenital Zika virus syndrome: An unprecedented clinical finding.

Seizure 2020 Oct 21;81:250-253. Epub 2020 Aug 21.

Universidade Federal do Ceará, Brazil.

Background: Brazil experienced a disproportionately higher rate of microcephaly cases in November 2015 with evidence of a causal link with Zika virus (ZIKV) infections during pregnancy. Epilepsy is a major neurological feature seen as part of congenital Zika virus syndrome (CZVS). Different seizure types and electroencephalographic (EEG) abnormalities have been described in association with this syndrome. Read More

View Article and Full-Text PDF
October 2020

Head mounted telemetry system for seizures monitoring and sleep scoring on non-human primate.

J Neurosci Methods 2020 12 19;346:108915. Epub 2020 Aug 19.

Yerkes National Primate Research Center, Emory University, Atlanta, United States; Department of Neurology, School of Medicine, Emory University, United States. Electronic address:

Radio telemetry systems are a useful way to continuously monitor broad electrical neuronal activity in behaving animals. It can also be used to study sleep disturbances or monitor seizure activity. Many different telemeter styles are available, but the more versatile and cost-efficient ones are the head mounted systems. Read More

View Article and Full-Text PDF
December 2020

Cefepime-Induced Seizures: The Overlooked Outpatient Adverse Reaction.

Cureus 2020 Jul 19;12(7):e9268. Epub 2020 Jul 19.

Medicine, State University of New York (SUNY) Upstate Medical University, Syracuse, USA.

Cefepime is a 4th generation cephalosporin often used for its ability to cover gram-positives, gram negatives, anaerobic bacteria, and, most importantly, pseudomonas. Prior to initiation of cefepime, the medication is dosed based on the renal function to avoid a multitude of its toxicity profiles, including encephalopathy, aphasia, myoclonus, seizures, and nonconvulsive status epilepticus. These risks are increased in the presence of renal impairment. Read More

View Article and Full-Text PDF

[A Case of Anterior Cranial Fossa Dural Arteriovenous Fistula Involving Uncontrolled Seizures Diagnosed Based on Characteristic Findings on Arterial Spin-labeling Imaging].

No Shinkei Geka 2020 Jun;48(6):547-552

Department of Neurosurgery, Division of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki.

We report a case of anterior cranial fossa dural arteriovenous fistula(ACF-DAVF)in a patient whose diagnosis was made according to characteristic findings on arterial spin labeling(ASL)MRI. CASE:A 68-year-old man was admitted to our hospital because of intractable epilepsy. Based on the initial MRI findings, an initial diagnosis of limbic encephalitis was made. Read More

View Article and Full-Text PDF

Status epilepticus as an initial presentation of aortic dissection: A case report.

Technol Health Care 2021 ;29(2):357-360

Background: Status epilepticus (SE) as the initial presentation of aortic dissection in the absence of chest pain is very rare. We report a case of aortic dissection (AD), which presented as SE with markedly elevated levels of D-dimer, a reliable and sensitive index of fibrin deposition and stabilization.

Case Report: A 74-year-old Asian woman presented to the emergency department (ED) with an altered mental state following three consecutive generalized tonic-clonic seizures at home. Read More

View Article and Full-Text PDF
January 2021

Clinical outcomes and treatments effectiveness in status epilepticus resolved by antiepileptic drugs: A five-year observational study.

Epilepsia Open 2020 Jun 2;5(2):166-175. Epub 2020 Mar 2.

Neurology Unit OCB Hospital Azienda Ospedaliera-Universitaria Modena Italy.

Objective: To evaluate clinical outcomes and treatment effectiveness of status epilepticus finally resolved by nonbenzodiazepine antiepileptic drugs (AEDs).

Methods: All consecutive SE episodes observed from September 1, 2013, to September 1, 2018, and resolved by AEDs were considered. Diagnosis and classification of SE followed the 2015 ILAE proposal. Read More

View Article and Full-Text PDF

Successful early diagnosis and treatment of non-convulsive status epilepticus-induced Takotsubo syndrome.

Intractable Rare Dis Res 2020 May;9(2):123-125

Department of Neurosurgery, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan.

Takotsubo syndrome (TTS) is often preceded by emotional or physical stress. Epileptic seizures have been described in more than 100 TTS cases. Due to the lack of typical symptoms, seizure-induced TTS can be overlooked. Read More

View Article and Full-Text PDF

How to carry out and interpret EEG recordings in COVID-19 patients in ICU?

Clin Neurophysiol 2020 08 13;131(8):2023-2031. Epub 2020 May 13.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

There are questions and challenges regarding neurologic complications in COVID-19 patients. EEG is a safe and efficient tool for the evaluation of brain function, even in the context of COVID-19. However, EEG technologists should not be put in danger if obtaining an EEG does not significantly advance diagnosis or change management in the patient. Read More

View Article and Full-Text PDF

Diagnosis and long-term management of post-traumatic seizures in a white-crowned pionus ().

J Am Vet Med Assoc 2020 May;256(10):1145-1152

Case Description: A 13-year-old female white-crowned pionus () was examined because of seizures 22 months after it was treated for a traumatic brain injury (TBI) characterized by vision loss, hemiparesis, nystagmus, circling, and head tilt.

Clinical Findings: Bloodwork performed during the initial seizure workup revealed hypercalcemia and hypercholesterolemia, which were attributed to vitellogenesis given the bird's previous egg-laying history and recent onset of reproductive behavior. Magnetic resonance imaging of the brain revealed diffuse right pallium atrophy with multifocal hydrocephalus ex vacuo, which were believed to be the result of the previous TBI. Read More

View Article and Full-Text PDF