56,645 results match your criteria epidemiology covid-19

Effect of the COVID-19 Pandemic Preparation and Response on Essential Health Services in Primary and Tertiary Healthcare Settings of Amhara Region, Ethiopia.

Am J Trop Med Hyg 2021 Sep 20. Epub 2021 Sep 20.

Amsterdam UMC, University of Amsterdam, Department of Dermatology, Amsterdam Institute for Infection and Immunity (AI&I), Location Academic Medical Centre, Amsterdam, The Netherlands.

Countries like Ethiopia have had to make difficult decisions to balance between the demands of the COVID-19 pandemic and maintaining the essential health service delivery. We assessed the effect of preventive COVID-19 measures on essential healthcare services in selected health facilities of Ethiopia. In a comparative cross-sectional study, we analyzed and compared data from seven health facilities over two periods: the pre-COVID-19 period before the first reported COVID-19 case in the country and during the COVID-19 period. Read More

View Article and Full-Text PDF
September 2021

Case Report: Paucisymptomatic College-Age Population as a Reservoir for Potentially Neutralization-Resistant Severe Acute Respiratory Syndrome Coronavirus 2 Variants.

Am J Trop Med Hyg 2021 Sep 20. Epub 2021 Sep 20.

Global Health Research Complex, Division of Research, Texas A&M University, College Station, Texas.

To better understand the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant lineage distribution in a college campus population, we carried out viral genome surveillance over a 7-week period from January to March 2021. Among the sequences were three novel viral variants: BV-1 with a B.1. Read More

View Article and Full-Text PDF
September 2021

A snapshot of the immunogenicity, efficacy and safety of a full course of BNT162b2 anti-SARS-CoV-2 vaccine in cancer patients treated with PD-1/PD-L1 inhibitors: a longitudinal cohort study.

ESMO Open 2021 Sep 1;6(5):100272. Epub 2021 Sep 1.

Molecular Virology Unit, Department of Microbiology and Virology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Background: Very few cancer patients were enrolled in coronavirus disease-2019 vaccine studies. In order to address this gap of knowledge, real-world studies are mandatory. The aim of this study was to assess both humoral and cellular response after a messenger RNA vaccination schedule. Read More

View Article and Full-Text PDF
September 2021

Associations between older African academics' physical activity, walkability and mental health: a social distancing perspective.

Health Promot Int 2021 Sep 20. Epub 2021 Sep 20.

Africa Centre for Epidemiology, Gerontology and Geriatric Care, Accra North, Ghana.

This study aimed to assess the moderating influence of neighborhood walkability on the association between physical activity (PA) and mental health among older African academics aged 50 years or more in cities with social distancing protocols in response to the Coronavirus disease 2019 (COVID-19). A total of 905 volunteer academics participated in the study. A hierarchical linear regression analysis was employed to conduct sensitivity analyses and test the study hypotheses. Read More

View Article and Full-Text PDF
September 2021

Knowledge, attitudes, and practices of face mask utilization and associated factors in COVID-19 pandemic among Wachemo University Students, Southern Ethiopia: A cross-sectional study.

PLoS One 2021 20;16(9):e0257609. Epub 2021 Sep 20.

Department of Reproductive Health, College of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia.

Introduction: The widespread use of face masks by the general public may help to prevent the spread of viruses. Face masks are thought to be a good strategy to protect against respiratory diseases such as the Coronavirus. Identifying student knowledge, attitude, and practice about the use of face masks is crucial to detect vulnerabilities and respond rapidly to avoid the spread of the infection. Read More

View Article and Full-Text PDF
September 2021

Analysis of social interactions and risk factors relevant to the spread of infectious diseases at hospitals and nursing homes.

PLoS One 2021 20;16(9):e0257684. Epub 2021 Sep 20.

DTU Compute, Technical University of Denmark, Lyngby, Denmark.

Ensuring the safety of healthcare workers is vital to overcome the ongoing COVID-19 pandemic. We here present an analysis of the social interactions between the healthcare workers at hospitals and nursing homes. Using data from an automated hand hygiene system, we inferred social interactions between healthcare workers to identify transmission paths of infection in hospitals and nursing homes. Read More

View Article and Full-Text PDF
September 2021

A multi-component, community-based strategy to facilitate COVID-19 vaccine uptake among Latinx populations: From theory to practice.

PLoS One 2021 20;16(9):e0257111. Epub 2021 Sep 20.

Division of HIV, Infectious Diseases and Global Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, University of California San Francisco, San Francisco, California, United States of America.

Background: COVID-19 vaccine coverage in the Latinx community depends on delivery systems that overcome barriers such as institutional distrust, misinformation, and access to care. We hypothesized that a community-centered vaccination strategy that included mobilization, vaccination, and "activation" components could successfully reach an underserved Latinx population, utilizing its social networks to boost vaccination coverage.

Methods: Our community-academic-public health partnership, "Unidos en Salud," utilized a theory-informed approach to design our "Motivate, Vaccinate, and Activate" COVID-19 vaccination strategy. Read More

View Article and Full-Text PDF
September 2021

Algorithm for Individual Prediction of COVID-19 Hospitalization from Symptoms: Development and Implementation Study.

JMIR Public Health Surveill 2021 Sep 14. Epub 2021 Sep 14.

Epidemiology Unit, Agency for the Protection of Health of the Metropolitan Area of Milan, Via Conca del Naviglio 45, Milan, IT.

Background: The coronavirus disease 2019 (COVID-19) pandemic has generated a huge strain on the health care system worldwide. The metropolitan area of Milan, Italy was one of the most hit area in the world.

Objective: Risk prediction models developed combining administrative data bases and basic clinical data are needed to stratify individual patient risk for public health purposes. Read More

View Article and Full-Text PDF
September 2021

Mechanical ventilation for older medical patients in a large tertiary medical care center.

Eur Geriatr Med 2021 Sep 20. Epub 2021 Sep 20.

The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.

Background: The development of technologies for the prolongation of life has resulted in an increase in the number of older ventilated patients in internal medicine and chronic care wards. Our study aimed to determine the factors influencing the outcomes of older ventilated medical patients in a large tertiary medical center.

Methods: We performed a prospective observational cohort study including all newly ventilated medical patients aged 65 years and older over a period of 18 months. Read More

View Article and Full-Text PDF
September 2021

SARS-CoV-2 adsorption on suspended solids along a sewerage network: mathematical model formulation, sensitivity analysis, and parametric study.

Environ Sci Pollut Res Int 2021 Sep 17. Epub 2021 Sep 17.

Faculty of Veterinary Medicine, School of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.

Accounting for SARS-CoV-2 adsorption on solids suspended in wastewater is a necessary step towards the reliable estimation of virus shedding rate in a sewerage system, based on measurements performed at a terminal collection station, i.e., at the entrance of a wastewater treatment plant. Read More

View Article and Full-Text PDF
September 2021

Migrants on the Move and Food (In)security: A Call for Research.

J Immigr Minor Health 2021 Sep 20. Epub 2021 Sep 20.

Instituto Nacional de Salud Pública, Cuernavaca, Mexico.

Food insecurity contributes to negative outcomes for health and wellbeing, and its impact may be exacerbated during periods of vulnerability. While food insecurity is both a driver and a consequence of migration, anecdotal evidence indicates that it is also common during migration when people are 'on the move', although its prevalence and severity during these periods are largely undocumented. Food security monitoring is critical to ensuring the universal right to food for migrants, and instruments must be designed which capture the unique challenges faced during these 'extra-ordinary' periods of mobility, including in the context of emergencies such as the COVID-19 pandemic. Read More

View Article and Full-Text PDF
September 2021

[COVID-19: epidemiology and mutations : An update].

Radiologe 2021 Sep 20. Epub 2021 Sep 20.

Abteilung für Tropenmedizin und Infektionskrankheiten, Universitätsmedizin Rostock, Ernst-Heydemann-Straße 5, 18057, Rostock, Deutschland.

Mutations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enhance the spread and the infectiousness and decrease the protective effect of antibodies present after infection, vaccination or antibody treatment. The alpha variant (B.1. Read More

View Article and Full-Text PDF
September 2021

Air travel-related outbreak of multiple SARS-CoV-2 variants.

J Travel Med 2021 Sep 20. Epub 2021 Sep 20.

School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

Background: A large cluster of 59 cases were linked to a single flight with 146 passengers from New Delhi to Hong Kong in April 2021. This outbreak coincided with early reports of exponential pandemic growth in New Delhi, which reached a peak of > 400 000 newly confirmed cases on 7 May 2021.

Methods: Epidemiological information including date of symptom onset, date of positive-sample detection, and travel and contact history for individual cases from this flight were collected. Read More

View Article and Full-Text PDF
September 2021

Spatial clusters, social determinants of health and risk of maternal mortality by COVID-19 in Brazil: a national population-based ecological study.

Lancet Reg Health Am 2021 Nov 10;3:100076. Epub 2021 Sep 10.

Health Science Graduate Program, Federal University of Sergipe, Aracaju, Brazil.

Background: Detailed information on how socio-economic characteristics are related to COVID-19 incident cases and maternal deaths is needed. We investigated the spatial distribution of COVID-19 cases and maternal deaths in Brazil and their association with social determinants of health.

Methods: This was a population-based ecological study with a spatial analysis of all cases and deaths of COVID-19 in the obstetric population. Read More

View Article and Full-Text PDF
November 2021

Public Attitudes and Factors of COVID-19 Testing Hesitancy in the United Kingdom and China: Comparative Infodemiology Study.

JMIR Infodemiology 2021 Jan-Dec;1(1):e26895. Epub 2021 Aug 27.

School of Public Health Fudan University Shanghai China.

Background: Massive community-wide testing has become the cornerstone of management strategies for the COVID-19 pandemic.

Objective: This study was a comparative analysis between the United Kingdom and China, which aimed to assess public attitudes and uptake regarding COVID-19 testing, with a focus on factors of COVID-19 testing hesitancy, including effectiveness, access, risk perception, and communication.

Methods: We collected and manually coded 3856 UK tweets and 9299 Chinese Sina Weibo posts mentioning COVID-19 testing from June 1 to July 15, 2020. Read More

View Article and Full-Text PDF

New Metrics for Assessing the State Performance in Combating the COVID-19 Pandemic.

Geohealth 2021 Sep 1;5(9):e2021GH000450. Epub 2021 Sep 1.

Department of Geography and GeoInformation Science George Mason University Fairfax VA USA.

Previous research has noted that many factors greatly influence the spread of COVID-19. Contrary to explicit factors that are measurable, such as population density, number of medical staff, and the daily test rate, many factors are not directly observable, for instance, culture differences and attitudes toward the disease, which may introduce unobserved heterogeneity. Most contemporary COVID-19 related research has focused on modeling the relationship between explicitly measurable factors and the response variable of interest (such as the infection rate or the death rate). Read More

View Article and Full-Text PDF
September 2021

Follow-Ups on Persistent Symptoms and Pulmonary Function Among Post-Acute COVID-19 Patients: A Systematic Review and Meta-Analysis.

Front Med (Lausanne) 2021 3;8:702635. Epub 2021 Sep 3.

Department of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, China.

As the number of recovering COVID-19 patients increases worldwide, the persistence of symptoms and signs through the post-acute phase indicates an urgent need for prolonged follow-up care. To explore existing data about post-acute COVID-19 syndrome, this meta-analysis assesses the prevalence of persistent manifestations in multiple systems and abnormalities in lung function, as well as their related risks in patients with various severities. Articles about discharged COVID-19 patients (published from January 1, 2020 to February 23, 2021) were obtained by searching four databases. Read More

View Article and Full-Text PDF
September 2021

Global COVID-19 pandemic waves: Limited lessons learned worldwide over the past year.

Engineering (Beijing) 2021 Sep 14. Epub 2021 Sep 14.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, China.

The occurrence of coronavirus disease 2019 (COVID-19) was followed by a small burst of cases around the world; afterward, due to a series of emergency non-pharmaceutical interventions (NPIs), the increasing number of confirmed cases slowed down in many countries. However, the subsequent gradual easing of governance led to a sudden increase in cases in late July 2020, arousing deep concern across the globe. This study evaluates the situation of the COVID-19 pandemic in countries and territories worldwide from January 2020 to February 2021. Read More

View Article and Full-Text PDF
September 2021

Descriptive epidemiology of the first wave of COVID-19 in Petaling District, Malaysia: Focus on asymptomatic transmission.

Western Pac Surveill Response J 2021 Apr-Jun;12(2):82-88. Epub 2021 Apr 21.

Petaling District Health Office, Selangor, Malaysia.

Background: COVID-19 was first detected in Malaysia on 25 January 2020. Multiple clusters were detected in Petaling District, with the first locally transmitted case reported on 8 February. Descriptive analyses of the epidemiology of the COVID-19 outbreak in Petaling are presented, from the first case to the end of the first wave. Read More

View Article and Full-Text PDF

Early reports of epidemiological parameters of the COVID-19 pandemic.

Western Pac Surveill Response J 2021 Apr-Jun;12(2):65-81. Epub 2021 May 11.

National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australian Capital Territory, Australia.

Background: The emergence of a new pathogen requires a rapid assessment of its transmissibility, to inform appropriate public health interventions.

Methods: The peer-reviewed literature published between 1 January and 30 April 2020 on COVID-19 in PubMed was searched. Estimates of the incubation period, serial interval and reproduction number for COVID-19 were obtained and compared. Read More

View Article and Full-Text PDF

The first community outbreak of COVID-19 in Viet Nam: description and lessons learned.

Western Pac Surveill Response J 2021 Apr-Jun;12(2):42-50. Epub 2019 Apr 27.

National Institute of Hygiene and Epidemiology, Ministry of Health, Hanoi, Viet Nam.

Objective: At the time of this study, the prevention of novel coronavirus disease 2019 (COVID-19) relied solely on nonpharmaceutical interventions. Implementation of these interventions is not always optimal and, consequently, several cases were imported into non-epidemic areas and led to large community outbreaks. This report describes the characteristics of the first community outbreak of COVID-19 in Viet Nam and the intensive preventive measures taken in response. Read More

View Article and Full-Text PDF

All around suboptimal health - a joint position paper of the Suboptimal Health Study Consortium and European Association for Predictive, Preventive and Personalised Medicine.

EPMA J 2021 Sep 13:1-31. Epub 2021 Sep 13.

Suboptimal Health Study Consortium, Kumasi, Ghana.

First two decades of the twenty-first century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of patients diagnosed with cardiovascular diseases and the type 2 diabetes mellitus, breast, lung, liver and prostate malignancies, neurological, sleep, mood and eye disorders, amongst others. Consequent socio-economic burden is tremendous. Unprecedented decrease in age of maladaptive individuals has been reported. Read More

View Article and Full-Text PDF
September 2021

The mRNA-1273 Vaccine Induces Cross-Variant Antibody Responses to SARS-CoV-2 With Distinct Profiles in Individuals With or Without Pre-Existing Immunity.

Front Immunol 2021 3;12:737083. Epub 2021 Sep 3.

Translational Clinical Research Program, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, Spain.

mRNA-based vaccines effectively induce protective neutralizing antibodies against SARS-CoV-2, the etiological agent of COVID-19. Yet, the kinetics and compositional patterns of vaccine-induced antibody responses to the original strain and emerging variants of concern remain largely unknown. Here we characterized serum antibody classes and subclasses targeting the spike receptor-binding domain of SARS-CoV-2 wild type and α, β, γ and δ variants in a longitudinal cohort of SARS-CoV-2 naïve and COVID-19 recovered individuals receiving the mRNA-1273 vaccine. Read More

View Article and Full-Text PDF
September 2021

Favipiravir Versus Arbidol for Clinical Recovery Rate in Moderate and Severe Adult COVID-19 Patients: A Prospective, Multicenter, Open-Label, Randomized Controlled Clinical Trial.

Front Pharmacol 2021 2;12:683296. Epub 2021 Sep 2.

Clinical Trial Center, Zhongnan Hospital of Wuhan University, Wuhan, China.

In addition to supportive therapy, antiviral therapy is an effective treatment for coronavirus disease 2019 (COVID-19). To compare the efficacy and safety of favipiravir and umifenovir (Arbidol) to treat COVID-19 patients. We conducted a prospective, randomized, controlled, open-label multicenter trial involving adult patients with COVID-19. Read More

View Article and Full-Text PDF
September 2021

Impaired psychological well-being of healthcare workers in a German department of anesthesiology is independent of immediate SARS-CoV-2 exposure - a longitudinal observational study.

Ger Med Sci 2021 1;19:Doc11. Epub 2021 Sep 1.

Department of Anesthesiology, Würzburg University Hospital, Würzburg, Germany.

The study aimed to assess the mental well-being of healthcare professionals at a German department of anesthesiology and critical care with a specialized ICU for treatment of COVID-19 patients during the first two peaks of the 2020 pandemic, and identifying risk and protective factors. A single-center longitudinal, online-based survey was conducted in healthcare workers from a department of anesthesiology and critical care in Bavaria, the most affected federal state in Germany at the time of assessment. Validated scores for depression, anxiety, somatic disorders, burnout, resilience, and self-management were used and complemented by questions about perceived COVID-19-related stressors. Read More

View Article and Full-Text PDF
September 2021

A nanoenzyme linked immunochromatographic sensor for rapid and quantitative detection of SARS-CoV-2 nucleocapsid protein in human blood.

Sens Actuators B Chem 2021 Sep 12:130718. Epub 2021 Sep 12.

Department of Transfusion Medicine, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China.

The establishment of a simple, low-cost, high-sensitive and rapid immunoassay for detecting SARS-CoV-2 antigen in human blood is an effective mean of discovering early SARS-CoV-2 infection and controlling the pandemic of COVID-19. Herein, a smartphone based nanozyme linked immunochromatographic sensor (NLICS) for the detection of SARS-CoV-2 nucleocapsid protein (NP) has been developed on demand. The system is integrated by disposable immunochromatography assay (ICA) and optical sensor devices. Read More

View Article and Full-Text PDF
September 2021

Factors Associated With Severe COVID-19 Infection Among Persons of Different Ages Living in a Defined Midwestern US Population.

Mayo Clin Proc 2021 Jul 5. Epub 2021 Jul 5.

Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.

Objective: To identify risk factors associated with severe COVID-19 infection in a defined Midwestern US population overall and within different age groups.

Patients And Methods: We used the Rochester Epidemiology Project research infrastructure to identify persons residing in a defined 27-county Midwestern region who had positive results on polymerase chain reaction tests for COVID-19 between March 1, 2020, and September 30, 2020 (N=9928). Age, sex, race, ethnicity, body mass index, smoking status, and 44 chronic disease categories were considered as possible risk factors for severe infection. Read More

View Article and Full-Text PDF

Neurological Effects of COVID-19 in Children.

Pediatr Clin North Am 2021 Oct;68(5):1081-1091

Department of Pediatric Neurology, Children's Hospital of Michigan Specialty Center, 2nd Floor, 3950 Beaubien Street, Detroit, MI 48202, USA; Department of Pediatrics, Central Michigan University, Pleasant, MI, USA; Department of Neurology, Central Michigan University, Pleasant, MI, USA. Electronic address:

The COVID-19 pandemic has spread rapidly across the world in 2020, affecting both adults and, to a lesser extent, children. In this article, the authors describe the neurologic manifestations of COVID-19 in children, including the epidemiology, pathogenesis, clinical features, laboratory and imaging findings, and treatment options. The management of patients with concomitant neuroimmunologic disorders and drug interactions between medications used to treat COVID-19 and other neurologic disorders (especially immune-modifying drugs) is also discussed. Read More

View Article and Full-Text PDF
October 2021