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Psychometric Properties of the Lasher and Faulkender Anxiety about Aging Scale (AAS) among Iranian Older Adults.

Eur J Investig Health Psychol Educ 2021 Jul 28;11(3):829-837. Epub 2021 Jul 28.

Department of Health Education & Promotion, Tabriz University of Medical Sciences, Tabriz 14711, Iran.

(1) Background: The older adult population of society is exposed to multiple stressors daily, such as the loss of loved ones, dysfunctional mobility, financial dependence, and suffering from numerous chronic illnesses. The present study aimed to assess the psychometric properties of the Anxiety about Aging Scale among older adults in Iran. (2) Methods: A sample of 703 community-dwelling older adults was recruited and screened using a standardized tool. Read More

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Functional Status among Polymedicated Geriatric Inpatients at Discharge: A Population-Based Hospital Register Analysis.

Geriatrics (Basel) 2021 Sep 3;6(3). Epub 2021 Sep 3.

School of Health Sciences, HES-SO Valais/Wallis, 1950 Sion, Switzerland.

This study explored and compared the functional status of polymedicated and non-polymedicated geriatric inpatients at hospital discharge. We used a cross-sectional registry of geriatric patients' hospital records from a multi-site public hospital center in Switzerland. The analysis included all inpatients aged 65 years old or more admitted between 1 January 2015 and 31 December 2017 (n = 53,690), of whom 67. Read More

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September 2021

Triglyceride/Glucose Index (TyG Index) as a marker of glucose status conversion among reproductive-aged women in Jakarta, Indonesia: The Bogor cohort study (2011-2016).

Diabetes Metab Syndr 2021 Sep 11;15(6):102280. Epub 2021 Sep 11.

Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

Background And Aims: Reproductive-aged women are prone to type 2 diabetes mellitus. This study aims to evaluate the optimal cut off point of Triglyceride/Glucose Index for predicting glucose status conversion among women of reproductive age.

Methods: This study involved normoglycemic and prediabetes women aged 20-49 years from the Bogor Non-Communicable Diseases Cohort Study (West Java, Indonesia) conducted from 2011 to 2016. Read More

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September 2021

Global prevalence and associated risk factors of diarrheagenic Giardia duodenalis in HIV/AIDS patients: A systematic review and meta-analysis.

Microb Pathog 2021 Sep 22:105202. Epub 2021 Sep 22.

Department of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Giardia duodenalis is one of the leading causes of diarrhea, mostly in underdeveloped nations of Africa and Asia. The present review provides insights into the prevalence, odds ratios (ORs) and associated risk factors of giardiasis in HIV/AIDS patients. Four major English databases (Web of Science, PubMed, Scopus, and Google Scholar) were excavated for relevant literature without time limitation until 20 November 2020. Read More

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September 2021

Estimated effect of increased diagnosis, treatment, and control of diabetes and its associated cardiovascular risk factors among low-income and middle-income countries: a microsimulation model.

Lancet Glob Health 2021 Sep 22. Epub 2021 Sep 22.

Institute for Applied Health Research, University of Birmingham, Birmingham, UK; Centre for Global Surgery, Department of Global Health, Stellenbosch University, Cape Town, South Africa; Medical Research Council-Wits University Rural Public Health and Health Transitions Research Unit, Faculty of Health Sciences, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa.

Background: Given the increasing prevalence of diabetes in low-income and middle-income countries (LMICs), we aimed to estimate the health and cost implications of achieving different targets for diagnosis, treatment, and control of diabetes and its associated cardiovascular risk factors among LMICs.

Methods: We constructed a microsimulation model to estimate disability-adjusted life-years (DALYs) lost and health-care costs of diagnosis, treatment, and control of blood pressure, dyslipidaemia, and glycaemia among people with diabetes in LMICs. We used individual participant data-specifically from the subset of people who were defined as having any type of diabetes by WHO standards-from nationally representative, cross-sectional surveys (2006-18) spanning 15 world regions to estimate the baseline 10-year risk of atherosclerotic cardiovascular disease (defined as fatal and non-fatal myocardial infarction and stroke), heart failure (ejection fraction of <40%, with New York Heart Association class III or IV functional limitations), end-stage renal disease (defined as an estimated glomerular filtration rate <15 mL/min per 1·73 m or needing dialysis or transplant), retinopathy with severe vision loss (<20/200 visual acuity as measured by the Snellen chart), and neuropathy with pressure sensation loss (assessed by the Semmes-Weinstein 5·07/10 g monofilament exam). Read More

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September 2021

Prevalence of collusion in cancer communications: A meta-analysis.

Psychooncology 2021 Sep 25. Epub 2021 Sep 25.

Department of Environmental Health and Epidemiology, Indian Council of Medical Research, National Institute for Research in Environmental Health, Bhopal, India.

Introduction: Collusion is the non-disclosure of information about diagnosis or prognosis, frequently encountered in cancer care and palliative services. Unraveling collusion is a skill and differences among communication techniques by Health Care Workers have maintained the process of non-disclosure to patients and caregivers. Identifying the prevalence of collusion in cancer care is required to improve the existing strategies across the world. Read More

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September 2021

Intravenous immunoglobulin and the current risk of moderate and severe anaphylactic events, a cohort study.

Clin Exp Immunol 2021 Sep 25. Epub 2021 Sep 25.

Clinical Associate Professor Sheryl van Nunen MB BS MM (Sleep Medicine) FRACP, Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia and Visiting Medical Officer, Clinical Immunology and Allergy, Northern Beaches Hospital, Frenchs Forest, NSW, 2065, Australia.

This large cohort study from the US Premier Healthcare Database evaluated the risk and predictors of anaphylaxis in association with intravenous immunoglobulin (IVIg) therapy in the inpatient and outpatient setting. Data were collected retrospectively (01/2009-12/2018) from 24,919 patients administered IgPro10 IVIg, median age 54 years. Immunoglobulins of interest were IgPro10 and other IVIg given before or after IgPro10. Read More

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September 2021

Right bundle branch block and risk of cardiovascular mortality: the Ibaraki Prefectural Health Study.

Heart Vessels 2021 Sep 25. Epub 2021 Sep 25.

Ibaraki Health Plaza, Ibaraki Health Service Association, Mito, Japan.

Historically, a right bundle branch block has been considered a benign finding in asymptomatic individuals. However, this conclusion is based on a few old studies with small sample sizes. We examined the association between a complete right bundle branch block (CRBBB) and subsequent cardiovascular mortality in the general population in Japan. Read More

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September 2021

Lack of documentation of lymph node examination in patients with squamous cell carcinoma of the lower lip.

Arch Dermatol Res 2021 Sep 25. Epub 2021 Sep 25.

Department of Dermatology, University of Wisconsin School of Medicine and Public Health, 1 South Park Street, Seventh Floor, Madison, WI, 53715, USA.

Cutaneous squamous cell carcinoma is the second most common cutaneous malignancy with a 5-year disease-specific survival rate of approximately 90%, which decreases dramatically to 50% in the presence of regional lymph node metastases. We sought to examine clinicians' documentation of pertinent neurological symptoms/signs and lymph node palpation at the time of initial biopsy and treatment using lower lip SCC patients as a cohort. Subsequently, we investigated the correlation between clinical and pathologic SCC features and the aforementioned documentation. Read More

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September 2021

Long-term diet quality and its change in relation to late-life subjective cognitive decline.

Am J Clin Nutr 2021 Sep 25. Epub 2021 Sep 25.

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Background: Evidence regarding the role of diet quality, especially its change, in subjective cognitive decline (SCD) is scarce.

Objectives: To examine associations of long-term diet qualities, including Alternate Mediterranean Diet (AMED), Dietary Approaches to Stop Hypertension (DASH), and Alternate Healthy Eating Index 2010 (AHEI-2010) with SCD in the Nurses' Health Study.

Methods: We followed 49,493 female registered nurses averaged 48 years from 1984 to 2014. Read More

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September 2021

Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A Two-Site Cross-Sectional Study of Four Racial Or Ethnic Groups.

J Nutr 2021 Sep 25. Epub 2021 Sep 25.

Division of Epidemiology and Community Health, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454.

Background: Valid biomarkers of fruit and vegetable (FV) intake are needed for field-based nutrition research.

Objective: To examine criterion-related validity of pressure-mediated reflection spectroscopy as a proxy measure of FV intake, using plasma carotenoids and self-reported FV and carotenoid intake as primary and secondary criterion measures, respectively.

Methods: Healthy adults 18-65 years of age, self-identifying as African American/ black (n = 61), Asian (n = 53), white (n = 70), or Hispanic (n = 29) in North Carolina and Minnesota were recruited. Read More

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September 2021

Objectively measured patterns of daily physical activity and phenotypic frailty.

J Gerontol A Biol Sci Med Sci 2021 Sep 25. Epub 2021 Sep 25.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Background: Self-reported low physical activity is a defining feature of phenotypic frailty but does not adequately capture physical activity performed throughout the day. This study examined associations between accelerometer-derived patterns of routine daily physical activity and frailty.

Methods: Wrist accelerometer and frailty data from 638 participants (mean age 77 (SD=5. Read More

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September 2021

Patients' preferences for quality-of-life aspects in sarcopenia: a best-worst scaling study.

Eur Geriatr Med 2021 Sep 25. Epub 2021 Sep 25.

Division of Public Health, Epidemiology and Health Economics, World Health Organization Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Ageing, University of Liège, Liège, Belgium.

Purpose: As information on patients' preferences regarding quality-of-life aspects in sarcopenia is lacking, this study aims to assess the relative importance of the 14 items of a QoL questionnaire designed for sarcopenia (the SF-SarQoL) using a best-worst scaling (BWS) survey.

Methods: Participants, aged 65 years or older and community dwelling, who previously participated in the SarcoPhAge study, received a BWS survey via the mail. An object case BWS was selected in which participants completed 12 choice tasks, picking the most and least important aspect from 4 out of 14 SF-SarQoL items for each task. Read More

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September 2021

Adolescent-Centered HIV Prevention: Perspectives on Acceptability of Oral Antiretroviral Pre-exposure Prophylaxis for Adolescents in a Global Priority Setting.

Arch Sex Behav 2021 Sep 24. Epub 2021 Sep 24.

Department of Behavioral and Social Sciences, Brown University, Providence, RI, USA.

With oral antiretroviral pre-exposure prophylaxis (PrEP) rollout expanding to include adolescents in South Africa, research is needed to better understand perceptions of PrEP acceptability among adolescents and clinical service providers. We conducted an exploratory mixed-methods study among 57 adolescents, 16-17 years of age, living with and without HIV, and 25 clinical service providers in Cape Town, South Africa from 2015 to 2016. Cross-sectional survey and semi-structured qualitative interview data were used to explore (1) willingness to use PrEP and support partner PrEP use among adolescents living with and without HIV, (2) willingness to prescribe or support prescription of PrEP among service providers, and (3) perceptions of barriers and facilitators to PrEP implementation and interpretations of PrEP efficacy messaging for adolescent HIV prevention among all participants. Read More

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September 2021

Sleep health mediates the relationship between physical activity and depression symptoms.

Sleep Breath 2021 Sep 24. Epub 2021 Sep 24.

Neuroscience Program, Washington and Lee University, Parmly Hall, 204 West Washington Street, Lexington, VA, 24450, USA.

Purpose: This study aimed to investigate cross-sectional associations between physical activity, sleep health, and depression symptoms using mediation models.

Methods: Participants (N = 1576, M = 39.3 years, 40% female) were recruited online from Amazon's Mechanical Turk crowd-sourcing service. Read More

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September 2021

Galectin-3 for prediction of cardiac function compared to NT-proBNP in individuals with prediabetes and type 2 diabetes mellitus.

Sci Rep 2021 Sep 24;11(1):19012. Epub 2021 Sep 24.

German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.

Use of galectin-3 for assessing cardiac function in prediabetes and type 2 diabetes mellitus (T2DM) needs to be established. Within the Gutenberg Health Study cohort (N = 15,010, 35-74 years) patient characteristics were investigated regarding galectin-3 levels. Prognostic value of galectin-3 compared to NT-proBNP concerning cardiac function and mortality was assessed in individuals with euglycaemia, prediabetes and T2DM in 5 years follow-up. Read More

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September 2021

Anal human papillomavirus prevalence among vaccinated and unvaccinated gay, bisexual, and other men who have sex with men in Canada.

Sex Transm Dis 2021 Sep 22. Epub 2021 Sep 22.

Dalla Lana School of Public Health, University of Toronto, Toronto, Canada MAP Centre for Urban Health Solutions, St. Michael's Hospital, Unity Health Toronto, Toronto, Canada Department of Health and Wellness, Government of Nova Scotia, Halifax, Canada ICES, Sunnybrook Research Institute, Toronto, Canada Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Canada McGill University Health Centre Research Institute, McGill University, Montréal, Canada Clinical Prevention Services, British Columbia Centre for Disease Control, Vancouver, Canada Department of Psychology, Ryerson University, Toronto, Canada Direction régionale de santé publique de Montréal, Montréal, Canada British Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada Département de microbiologie, infectiologie et immunologie, Université de Montréal, Montréal, Canada Laboratoire de virologie moléculaire, Centre de recherche du Centre hospitalier de l'Université de Montréal, Montréal, Canada Department of Family and Community Medicine, University of Toronto, Toronto, Canada.

Background: Starting in 2015, human papillomavirus (HPV) vaccine has been publicly funded for gay, bisexual, and other men who have sex with men (GBM) aged ≤26 years in Canada.

Methods: Self-identified GBM who reported having sex with another man within the past six months were enrolled using respondent-driven sampling (RDS) between February 2017 and August 2019 in Montreal, Toronto, and Vancouver, Canada. Men aged 16-30 years self-collected anal specimens for HPV-DNA testing. Read More

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September 2021

Risk of serious infection with low-dose glucocorticoids in patients with rheumatoid arthritis: an instrumental variable analysis.

Epidemiology 2021 Sep 20. Epub 2021 Sep 20.

University of Pennsylvania, Division of Rheumatology, Philadelphia, Pennsylvania, UA University of Pennsylvania, Department of Biostatistics, Epidemiology, and Informatics, Philadelphia, Pennsylvania, UA University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, Birmingham, Alabama, UA.

Background: Low-dose glucocorticoids are commonly used in the treatment of rheumatoid arthritis (RA). Observational studies have found increased risk of serious infection associated with low-dose glucocorticoids, but concerns about residual confounding remain.

Methods: We identified adults with RA on stable immunomodulatory therapy for >6 months receiving no glucocorticoids or ≤5mg/day using Medicare data from 2006-2015. Read More

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September 2021

The Role of Childhood Asthma in Obesity Development: A Nationwide U.S. Multi-cohort Study.

Epidemiology 2021 Sep 20. Epub 2021 Sep 20.

Department of Preventive Medicine, University of Southern California, Los Angeles, CA Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD Department of Civil and Environmental Engineering, Northeastern University, Boston, MA Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston MA Department of Pediatrics, Hackensack Meridian School of Medicine, Nutley NJ and the Albert Einstein College of Medicine, Bronx, NY Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN Departments of Pediatrics and Medicine, The University of Chicago, Chicago, IL University of Colorado, Anschutz Medical Campus, Aurora, CO Nell Hodgson Woodruff School of Nursing and Department of Family & Preventive Medicine, Emory University, Atlanta, GA Avera Research Institute, Sioux Falls, SD Kaiser Permanente Northern California Division of Research Department of Psychology The George Washington University, Washington, DC Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA University of California, Davis, School of Medicine, CA Geisel School of Medicine, Dartmouth College, Hanover, NH Department of Pediatrics & Environmental and Occupational Health Sciences, University of Washington, WA Department of Psychiatry and Human Behavior and Department of Pediatrics, Brown Alpert Medical School and Women and Infants Hospital, Providence, RI. Department of Education, University of Oregon, Eugene, OR Division of Pediatric Pulmonary Medicine, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY Department of Pediatrics, Oregon Health and Science University, Portland, OR Division of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY Departments of Psychiatry, Psychology, Neuroscience and Obstetrics and Gynecology, University of Rochester, NY Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT Division of Allergy, Immunology, and Pulmonary Medicine, Department of PediatricsSt. Louis Children's Hospital, Washington University School of Medicine St. Louis, MO Departments of Pediatrics, Environmental Medicine and Population Health, New York University School of Medicine, NY Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY Department of Internal Medicine, University of Utah, Salt Lake City, UT Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY.

Rationale: Asthma and obesity often co-occur. It has been hypothesized that asthma may contribute to childhood obesity onset.

Objectives: To determine if childhood asthma is associated with incident obesity and examine the role of asthma medication in this association. Read More

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September 2021

Accounting for Preinvasive Conditions in Analysis of Invasive Cancer Risk: Application to Breast Cancer.

Epidemiology 2021 Sep 20. Epub 2021 Sep 20.

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences Department of Biostatistics, University of North Carolina at Chapel Hill Epidemiology Branch, National Institute of Environmental Health Sciences.

Background: Preinvasive cancer conditions are often actively treated to minimize progression to life-threatening invasive cancers, but this creates challenges for analysis of invasive cancer risk. Conventional methods of treating preinvasive conditions as censoring events or targeting at the composite outcome could both lead to bias.

Methods: We propose two solutions: one that provides exact estimates of risk based on distributional assumptions about progression, and one that provides risk bounds corresponding to extreme cases of no or complete progression. Read More

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September 2021

Public acceptability of the UK Soft Drinks Industry Levy: repeat cross-sectional analysis of the International Food Policy Study (2017-2019).

BMJ Open 2021 Sep 24;11(9):e051677. Epub 2021 Sep 24.

MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.

Objectives: To determine whether public acceptability, in terms of both support for and perceived effectiveness of, the UK Soft Drinks Industry Levy (SDIL) changed between 4 months prior to, and 8 and 20 months after, implementation.

Design: Repeat cross-sectional online survey.

Setting: The UK. Read More

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September 2021

Knowledge, attitude and practice of antibiotics and their determinants in Eritrea: an urban population-based survey.

BMJ Open 2021 Sep 24;11(9):e046432. Epub 2021 Sep 24.

Department of Statistics, Eritrean Institute Technology, Asmara, Eritrea.

Objective: To measure knowledge, attitude and practice of antibiotics and antibiotic resistance (ABR) and their determinants in the Eritrean urban population.

Design: A population-based, nation-wide, cross-sectional study.

Setting: Urban settings of Eritrea. Read More

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September 2021

Derivation and validation of a risk score for admission to the Intensive Care Unit in patients with COVID-19.

Rev Clin Esp (Barc) 2021 Sep 14. Epub 2021 Sep 14.

Departamento de Medicina Interna, Hospital Regional de Málaga, Instituto de Investigación Biomédica (IBIMA), Universidad de Málaga, Málaga, Spain.

Background: This work aims to identify and validate a risk scale for admission to intensive care units (ICU) in hospitalized patients with coronavirus disease 2019 (COVID-19).

Methods: We created a derivation rule and a validation rule for ICU admission using data from a national registry of a cohort of patients with confirmed SARS-CoV-2 infection who were admitted between March and August 2020 (N = 16,298). We analyzed the available demographic, clinical, radiological, and laboratory variables recorded at hospital admission. Read More

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September 2021

Frequency and severity of prehospital obstetric events encountered by emergency medical services in the United States.

BMC Pregnancy Childbirth 2021 Sep 24;21(1):655. Epub 2021 Sep 24.

Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Background: Prehospital obstetric events encountered by emergency medical services (EMS) can be high-risk patient presentations for which suboptimal care can cause substantial morbidity and mortality. The frequency of prehospital obstetric events is unclear because existing descriptions have reported obstetric and gynecological conditions together, without delineating specific patient presentations. Our objective was to identify the types, frequency, and acuity of prehospital obstetric events treated by EMS personnel in the US. Read More

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September 2021

Effectiveness of medical rehabilitation in persons with back pain - lessons learned from a German cohort study.

Disabil Rehabil 2021 Sep 24:1-9. Epub 2021 Sep 24.

Institute for Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany.

Purpose: Evidence for health-related effects of German medical rehabilitation programs for back pain is inconclusive. This cohort study aimed to examine the effectiveness of medical rehabilitation in residents with back pain (German Clinical Trial Register: DRKS00011554).

Material And Methods: A sample of 45 000 people aged 45-59 years was randomly drawn from two pension agencies. Read More

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September 2021

Association Between Hyperoxemia and Increased Cell-Free Plasma Hemoglobin During Cardiopulmonary Bypass in Infants and Children.

Pediatr Crit Care Med 2021 Sep 24. Epub 2021 Sep 24.

Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA. Department of Pediatrics, Division of Critical Care Medicine, Ochsner Hospital for Children, New Orleans, LA. Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA. Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA. UPMC Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA. Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA.

Objectives: To determine potential risk factors for severe hemolysis during pediatric cardiopulmonary bypass and examine whether supraphysiologic levels of oxygen and cardiopulmonary bypass duration are associated with hemolysis.

Design: Prospective observational study.

Setting: Cardiac ICU in a university-affiliated children's hospital. Read More

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September 2021

Antimicrobial Stewardship in Bronchiolitis: A Retrospective Cohort Study of Three PICUs in Canada.

Pediatr Crit Care Med 2021 Sep 27. Epub 2021 Sep 27.

Department of Pediatric Critical Care, Critical Care Center, King Fahad Medical City, Riyadh, Saudi Arabia. Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada. Division of Pediatric Critical Care, Department of Pediatrics, University of Toronto, Toronto, ON, Canada. Department of Pathology and Lab Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada. Division of Pediatric Critical Care, Department of Pediatrics, McGill University, Montreal, QC, Canada. Division of Pediatric Infectious Diseases, Department of Pediatrics, McGill University, Montreal, QC, Canada. Department of Microbiology, Infectious Diseases and Immunology, Université de Montréal, Montreal, QC, Canada. Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada. Division of Pediatric Critical Care, Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada. Research Institute of the McGill University Health Centre, Montreal, QC, Canada. Division of Pediatric Critical Care, Department of Pediatrics, Centre Hospitalier Universitaire Sainte Justine, Montreal, QC, Canada.

Objectives: To determine the association between the implementation of an antimicrobial stewardship program at a local PICU and to determine the association between the presence of an antimicrobial stewardship programs and antimicrobial use across three Canadian PICUs, among critically ill children with bronchiolitis.

Design: A multicenter retrospective cohort study.

Setting: Three Canadian PICUs over two winter seasons. Read More

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September 2021

Patterns of Mandibular Fractures in South Australia: Epidemiology, Treatment, and Clinical Outcomes.

J Craniofac Surg 2021 Sep 24. Epub 2021 Sep 24.

Australian Craniofacial Unit, Royal Adelaide Hospital, Women and Children's Hospital, University of Adelaide, Adelaide School of Medicine, University of Notre Dame, Sydney, Australia.

Introduction: The mandible is one of the most common facial bones to be injured with great clinical variability across countries caused by assaults, road traffic accidents, and falls.

Methods: A retrospective review was conducted for adult mandibular fractures from January 2012 to January 2017 at the Royal Adelaide Hospital, Adelaide. Our aim was to describe epidemiological trends of mandibular fractures, differences for sex and age, and clinical outcomes. Read More

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September 2021