31,209 results match your criteria enteral feeding

The correlation between gastric residual volumes and markers of gastric emptying: a post-hoc analysis of a randomized clinical trial.

JPEN J Parenter Enteral Nutr 2021 Jul 22. Epub 2021 Jul 22.

Clinical Evaluation Research Unit, Kingston Health Science Centre, Kingston, ON, Canada.

Background: The correlation between gastric residual volumes (GRV) and markers of gastric emptying (GE) in critically ill patients is unclear. This is especially true for ICU surgical patients as they are underrepresented in previous studies.

Methods: We conducted a post-hoc analysis of a multicenter trial that investigated the effectiveness of a promotility drug in increasing enteral nutrition intake. Read More

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Experiences with intestinal failure from an intestinal rehabilitation unit in a country without home parenteral nutrition.

JPEN J Parenter Enteral Nutr 2021 Jul 22. Epub 2021 Jul 22.

Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

Objective: For the first time, we aimed to report experiences with an intestinal rehabilitation unit (IRU) from a country without home parenteral nutrition (HPN).

Methods: We included all patients with a diagnosis of intestinal failure (IF) since the establishment of our IRU from February 2018 to February 2020. We further report on our protocols for management of enterocutaneous fistulas (ECF), short bowel syndrome (SBS), chronic intestinal pseudo-obstruction and motility disorders. Read More

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Fish oil-based lipid emulsion alleviates parenteral nutrition-associated liver diseases and intestinal injury in piglets.

JPEN J Parenter Enteral Nutr 2021 Jul 21. Epub 2021 Jul 21.

Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background And Aims: This study aimed to investigate the impact of fish oil-based lipid emulsion (FO) on enterohepatic injuries and intestinal microbiota in piglets of total parenteral nutrition (TPN).

Methods: Newborn piglets were divided into three groups, including enteral diet (the controls), TPN with 100% FO and TPN with MCT/LCT-based lipid emulsion (MCT/LCT) for 14 days. Serum biochemical indicators, hepatic and intestinal histology, and expression of genes associated with inflammation, oxidative stress, and lipid metabolism were measured. Read More

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Hypophosphatemia in critically ill pediatric patients receiving enteral and oral nutrition.

JPEN J Parenter Enteral Nutr 2021 Jul 21. Epub 2021 Jul 21.

State University of Campinas, Unicamp, Faculty of Medical Sciences, 126 Tessália Vieira de Camargo St., Barão Geraldo, Campinas, SP, Zip Code: 13083-887, Brazil.

Background: Hypophosphatemia (HP) is related to several comorbidities in pediatric intensive care units (PICUs). This study aimed to evaluate the incidence of HP in severely ill pediatric patients under oral and/or enteral nutrition. The secondary objectives were to investigate the association between HP and the inflammatory state, prolonged PICU length stay, severity, mortality, nutritional status, and protein, energy, calcium, vitamin D and phosphate intake METHODS: : A prospective, observational cohort study was conducted in a PICU of a quaternary hospital. Read More

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Clinical observation of individualized nutritional formula on inflammation index, immune status and gastrointestinal tolerance in patients with severe head injury.

Pak J Med Sci 2021 Jul-Aug;37(4):952-958

Qianqian Li, Department of Neuroscience Critical Care Unit, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.

Objectives: To evaluate the clinical significance of individualized nutritional formulas on inflammatory factors, immune status and gastrointestinal tolerance in patients with severe head injury.

Methods: A total of 80 patients with severe head injury who were hospitalized in Baoding No.1 Central Hospital from March 2017 to March 2020 were randomly divided into two groups with 40 cases in each group. Read More

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December 2020

Extremely low birth weight neonates with phenylketonuria require special dietary management.

Acta Paediatr 2021 Jul 21. Epub 2021 Jul 21.

Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General Faculty Hospital, Prague, Czech Republic.

Aim: Extremely low birth weight (ELBW) neonates require a high protein intake, but this can be challenging in the very rare cases when they also have phenylketonuria (PKU). This is due to a lack of suitable parenteral nutrition or enteral formula. Our aim was to analyse tolerance to phenylalanine in these infants. Read More

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Exudative Glutamine losses contribute to the high needs after burn injury.

JPEN J Parenter Enteral Nutr 2021 Jul 20. Epub 2021 Jul 20.

Service of Adult Intensive Care, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

Background: Burn patients characteristically have increased energy, glucose and protein requirements. Glutamine supplementation is strongly recommended during early phase treatment and is associated with improved immunity, wound healing, and reduced mortality. This study evaluated if early burn exudative losses might contribute to higher supplementation needs. Read More

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Handgrip strength stratifies the risk of covert and overt hepatic encephalopathy in patients with cirrhosis.

JPEN J Parenter Enteral Nutr 2021 Jul 20. Epub 2021 Jul 20.

Department of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.

Background: Handgrip strength (HGS) is a simple and convenient method to assess nutritional status in patients with cirrhosis. This retrospective study aimed to investigate the utility of HGS for predicting patients with covert hepatic encephalopathy (CHE) and patients at high risk of overt hepatic encephalopathy (OHE).

Methods: We reviewed 963 patients with cirrhosis and consequently enrolled eligible 270 patients. Read More

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Bile acid - farnesoid X receptor - fibroblast growth factor 19 axis in patients with short bowel syndrome: the randomized glepaglutide phase 2 trial.

JPEN J Parenter Enteral Nutr 2021 Jul 20. Epub 2021 Jul 20.

Department of Intestinal Failure and Liver Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Background: The gut-liver axis and enterohepatic circulation have gained increasing attention lately. Patients with short bowel syndrome (SBS) are, in fact, human knock-out models that may assist in the understanding of bile acid synthesis and regulation.

Objective: We evaluated effect of glepaglutide, a long-acting glucagon-like peptide-2 analog, on bile acid synthesis, the enterohepatic circulation of bile acids and liver biochemistry in patients with SBS. Read More

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ASPEN definitions in pediatric intestinal failure.

JPEN J Parenter Enteral Nutr 2021 Jul 21. Epub 2021 Jul 21.

Group for Improvement of Intestinal Function and Treatment, Department of Surgery, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

Pediatric intestinal failure (PIF) is a relatively rare disease entity which requires focused interdisciplinary care and specialized nutrition management. There has long been a lack of consensus in the definition of key terms related to PIF due to its rarity and plethora of small studies rather than large trials. As such, the American Society for Parenteral and Enteral Nutrition (ASPEN) Pediatric Intestinal Failure Section, composed of clinicians from a variety of disciplines caring for children with intestinal failure, is uniquely poised to provide insight into this definition void. Read More

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Catheter-related infection rates in patients on customized home parenteral nutrition compared to multi-chamber bags.

JPEN J Parenter Enteral Nutr 2021 Jul 20. Epub 2021 Jul 20.

Intestinal Failure Unit, Salford Royal NHS Foundation Trust.

Background: The risk of blood stream infections may be increased in hospitalized patients receiving ready-made multi-chamber parenteral nutrition bags (MCB) compared to customized parenteral nutrition (PN); however, as highlighted in recent international guidelines, there are no comparable data relating to home PN (HPN).

Methods: Data from a prospectively maintained database were analysed to compare incidence rates of catheter-related blood stream infections (CRBSI) between patients receiving customized HPN compared to MCB HPN at a national UK referral centre between May 2018 and August 2020.

Results: Sixty patients with chronic intestinal failure were commenced on MCB and 45 on customized HPN for a total of 5914 and 7641 catheter days respectively. Read More

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Impact of Propofol Sedation upon Caloric Overfeeding and Protein Inadequacy in Critically Ill Patients Receiving Nutrition Support.

Pharmacy (Basel) 2021 Jul 1;9(3). Epub 2021 Jul 1.

College of Pharmacy, Union University, Jackson, TN 38305, USA.

Propofol, a commonly used sedative in the intensive care unit, is formulated in a 10% lipid emulsion that contributes 1.1 kcals per mL. As a result, propofol can significantly contribute to caloric intake and can potentially result in complications of overfeeding for patients who receive concurrent enteral or parenteral nutrition therapy. Read More

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Effect of Home Enteral Nutrition on Nutritional Status, Body Composition and Quality of Life in Patients With Malnourished Intestinal Failure.

Front Nutr 2021 1;8:643907. Epub 2021 Jul 1.

Affiliated Jinling Hospital, Research Institute of General Surgery, Medical School of Nanjing University, Nanjing, China.

The ultimate goal of intestinal failure (IF) management is to maintain optimal nutritional status, improve the quality of life (QoL), and promote intestinal adaptation. Enteral nutrition support is safe and effective in patients with IF and plays a central role in the management of patients with IF. The purpose of this study was to evaluate the effect of home enteral nutrition on nutritional status, body composition (BC), QoL and other clinical outcomes in malnourished patients with intestinal failure. Read More

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The Use of High-Flow Nasal Cannula and the Timing of Safe Feeding in Children with Bronchiolitis.

Cureus 2021 Jun 15;13(6):e15665. Epub 2021 Jun 15.

Pediatric Critical Care, NYU Winthrop, Mineola, USA.

Objective The use of high-flow nasal cannula (HFNC) as non-invasive respiratory support in children with bronchiolitis has increased over the last several years. Several studies have investigated enteral feeding safety while on HFNC. This study compares the safety of oral feeding prior to and following implementation of an HFNC feeding guideline. Read More

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Identifying patients with malnutrition and improving use of nutrition interventions: A quality study in four US hospitals.

Nutrition 2021 May 30;91-92:111360. Epub 2021 May 30.

Abbott Nutrition, Columbus, Ohio, United States.

Objective: This study investigated how specific nutrition interventions were implemented at four US hospitals, compared rates of malnutrition diagnosis and assessment between physicians and registered dietitian nutritionists (RDNs), and examined how these differences affected the nutrition intervention received during patients' hospital stay.

Methods: Data on patients' nutrition status and nutrition interventions were collected from 16 669 hospital inpatient records. Data on intervention utilization for patients with differing nutrition assessments and diagnoses from different health care practitioners were compared using descriptive statistics and χ tests. Read More

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Experiences and needs of home caregivers for enteral nutrition: A systematic review of qualitative research.

Nurs Open 2021 Jul 17. Epub 2021 Jul 17.

The First Hospital of Jilin University, Changchun, Jilin Province, China.

Aims: To systematically identify, evaluate and synthesize the qualitative evidence on enteral nutrition of home caregivers.

Design: A qualitative evidence synthesis using the Sandelowski and Barroso methodology.

Data Sources: We reviewed articles from eight databases: CINAHL, Embase, PubMed, Web of Science, Cochrane, CNKI, Wanfang Data and CSTJ. Read More

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Nutrition rehabilitation-related complications in primary mitochondrial disorders.

Nutr Clin Pract 2021 Jul 16. Epub 2021 Jul 16.

Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Primary mitochondrial disorders (PMDs) comprise a group of hundreds of individual genetic diseases affecting mitochondrial function, including oxidative phosphorylation and energy production. The estimated prevalence of these disorders ranges from 2.9 to 20 cases per 100,000. Read More

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NeoCHIRP: A model for intestinal rehabilitation in the neonatal intensive care unit.

Nutr Clin Pract 2021 Jul 16. Epub 2021 Jul 16.

Division of Neonatology, BC Women's Hospital and Health Centre/University of British Columbia, Vancouver, British Columbia, Canada.

Multidisciplinary intestinal rehabilitation (IR) teams have transformed care in pediatric intestinal failure (IF). Although most children with IF are identified in the neonatal intensive care unit (NICU), IR teams may not be involved at this stage. We describe our collaborative model, blending NICU and IR expertise to optimize care. Read More

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Knowledge Levels and Practices About the Enteral Nutritional Practices of Informal Caregivers Caring for Patients Fed Through a Percutaneous Endoscopic Gastrostomy Tube: A Descriptive Observational Study.

Gastroenterol Nurs 2021 Jul 13. Epub 2021 Jul 13.

Guldan Kahveci, MSc, RN, Ümraniye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey. Semiha Akin, PhD, Msc, RN, is Professor, Hamidiye Faculty of Nursing, University of Health Sciences - Turkey, Istanbul, Turkey.

This research aimed to evaluate informal caregivers' knowledge of and practices with enteral nutrition in caring for patients fed through a percutaneous endoscopic gastrostomy tube. Knowledge levels of caregivers about nutritional practices and percutaneous endoscopic gastrostomy tube care practices for patients fed enterally are important to prevent possible complications associated with the percutaneous endoscopic gastrostomy tube in the early period. The research sample for this descriptive observational study consisted of 126 individuals caring for patients fed through a gastrostomy tube. Read More

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[Enteral feeding in extremely low birth weight infants with a gestational age of <28 weeks versus ≥ 28 weeks].

Ying Li Fan Wu

Zhongguo Dang Dai Er Ke Za Zhi 2021 Jul;23(7):690-695

Department of Neonatology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.

Objective: To investigate the condition of enteral feeding and the incidence of feeding intolerance (FI) in extremely low birth weight (ELBW) infants with a gestational age (GA) of < 28 weeks versus ≥ 28 weeks.

Methods: A retrospective analysis was performed for the ELBW infants who were admitted to the Department of Neonatology, The Third Affiliated Hospital of Guangzhou Medical University, from January 2018 to January 2020. According to GA, they were divided into two groups:GA < 28 weeks (=41) and GA ≥ 28 weeks (=38). Read More

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Evaluation of slurry sampling preparation of enteral nutrition formulations for multielement determination using inductively coupled plasma optical emission spectrometry.

Food Chem 2021 Jun 26;365:130474. Epub 2021 Jun 26.

Universidade Federal da Bahia, Instituto de Química, Departamento de Química Analítica, Campus Universitário de Ondina, 40170-115 Salvador, Bahia, Brazil; INCT de Energia e Ambiente - Universidade Federal da Bahia, Campus Universitário de Ondina, 40170-115 Salvador, Bahia, Brazil. Electronic address:

An analytical procedure for the multielement determination in enteral nutrition formulations employing slurry sampling and inductively coupled plasma optical emission spectrometry (ICP OES) is proposed. A two-level full-factorial design was applied to assess the influence of the presence of stabilizing agents (HNO, Triton X-100 and ethanol) on the composition of the slurry. Multiple response was established as a dependent variable. Read More

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[Assessment of nutritive status and its correction in oncological patients after operations in the hepatopancreatoduodenal zone].

Vopr Pitan 2021;90(3):77-83. Epub 2021 May 17.

Nonprofit Joint Stock Company "Medical University of Karaganda", 100000, Karaganda, Republic of Kazakhstan.

Surgical interventions in the hepatopancreatoduodenal zone in cancer patients are associated with high risk of nutritional deficiency in the postoperative period. This feature is due to both the volume of the operation itself (pancreatoduodenectomy), and the predominance of catabolic processes in the early postoperative period. In this regard, the monitoring of the main indicators of carbohydrate, protein and fat metabolism in the early postoperative period becomes fundamental for choosing the correct tactics of nutritional support for this patients. Read More

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Refeeding syndrome in a miniature donkey.

J Vet Emerg Crit Care (San Antonio) 2021 Jul 14. Epub 2021 Jul 14.

Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, Michigan.

Objective: To describe refeeding syndrome in an equid without a history of recognized risk factors.

Case Summary: Refeeding syndrome with marked hypophosphatemia developed in an aged miniature donkey gelding during treatment of suspected enterocolitis. Hypophosphatemia (manifested clinically as ileus and neuromuscular weakness) developed despite a short (3 day) history of hyporexia, increased body condition (7/9), and adherence to nutritional recommendations for critically ill equids. Read More

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Incomplete small bowel obstruction in a patient with ankylosing spondylitis.

Radiol Case Rep 2021 Sep 3;16(9):2505-2508. Epub 2021 Jul 3.

Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No.138, Sheng Li Road, Tainan 704, Taiwan.

Small bowel obstruction is a blockage in the small intestine, which is usually caused by adhesion scar tissue, hernia, medication, or malignancy. The symptoms of small bowel obstruction include nausea and vomiting of bile, abdominal distention and obstipation. We present a case of a 61-year-old man with ankylosing spondylitis and scoliosis, who suffered from incomplete small bowel obstruction due to unusual direction of duodenum and externally compressed by liver, gallbladder and pancreas. Read More

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September 2021

Monitoring Adult Patients for Intolerance to Gastric Tube Feedings.

Norma A Metheny

Am J Nurs 2021 Jul 7. Epub 2021 Jul 7.

Norma A. Metheny is the Dorothy A. Votsmier Endowed Chair in Nursing and professor emerita at Saint Louis University, St. Louis. Contact author: The author and planners have disclosed no potential conflicts of interest, financial or otherwise. A podcast with the author is available at www.ajnonline.com.

Abstract: Gastric tube feeding is a common and valuable intervention for patients in a variety of care settings. While tube feeding can save the lives of patients for whom oral feeding isn't possible, intolerance to tube feeding is a potential complication. This article discusses risk factors for feeding intolerance; the assessment of signs and symptoms of feeding intolerance; the various means of assessing gastric emptying, including the practice of monitoring gastric residual volume (GRV); the controversy surrounding GRV monitoring in assessing feeding tolerance; and the special considerations for monitoring feeding tolerance in acutely and critically ill adults with coronavirus disease 2019. Read More

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Medium-Chain Triglyceride Oil and Blood Lipids: A Systematic Review and Meta-Analysis of Randomized Trials.

J Nutr 2021 Jul 13. Epub 2021 Jul 13.

Boden Collaboration for Obesity, Nutrition, Exercise & Eating Disorders, D17-Charles Perkins Centre, University of Sydney, Sydney, Australia.

Background: Dietary saturated fat raises total cholesterol and LDL cholesterol levels. It is unclear whether these effects differ by the fatty acid chain lengths of saturated fats; particularly, it is unclear whether medium-chain fatty acids increase lipid levels.

Objectives: We conducted a systematic review to determine the effects of medium-chain triglyceride (MCT) oil, consisting almost exclusively of medium-chain fatty acids (6:0-10:0), on blood lipids. Read More

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Determinants of fatty acid content and composition of human milk fed to infants born weighing <1250 g.

Am J Clin Nutr 2021 Jul 13. Epub 2021 Jul 13.

Translational Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada.

Background: Infants born at very low birth weight (VLBW) are vulnerable to deficits in fatty acids (FAs) but little is known of factors that influence the intakes or composition of their human milk feeds.

Objectives: We aimed to identify sources of variability in the fat composition of human milk fed to VLBW infants and examine the impact of milk source (mother's own or donor) on fat and FA intakes.

Methods: Serial samples of mother's milk (n = 476) and donor milk (n = 53) fed to infants born weighing <1250 g (n = 114 infants from 100 mothers) were collected [Optimizing Mothers' Milk for Preterm Infants (OptiMoM) randomized clinical trial]. Read More

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Nasogastric or nasojejunal feeding in pediatric acute pancreatitis: a randomized controlled trial.

World J Pediatr 2021 Jul 12. Epub 2021 Jul 12.

Department of Gastroenterology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310052 , China.

Background: The aim of this study was to compare nasogastric (NG) feeding with nasojejunal (NJ) feeding when treating pediatric patients with acute pancreatitis (AP).

Methods: We performed a single-center, prospective, randomized, active-controlled trial involving 77 pediatric patients with AP from April 2014 to December 2017. The patients were randomized into two groups: the NG tube feeding group (34 patients) and the NJ tube feeding group (33 patients). Read More

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[Interobserver agreement in using a checklist for the safe administration of enteral nutrition].

Nutr Hosp 2021 Jul 12. Epub 2021 Jul 12.

Programa de Pós-Graduação em Enfermagem da Universidade Federal do Rio Grande do Sul (PPGENF/UFRGS).

Objective: to describe an evaluation of interobserver agreement in the use of a checklist related to the use of nasoenteral tube (NSS) as a presupposition for quality in obtaining data.

Method: a methodological study conducted in 2018 in a Brazilian hospital, preceding the data collection of an open-label clinical trial. Independent observers, blinded to the evaluation of their peers, evaluated patients with NSS through a 25-item checklist. Read More

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Exocrine Pancreatic Maturation in Pre-term and Term Piglets Supplemented With Bovine Colostrum.

Front Nutr 2021 24;8:687056. Epub 2021 Jun 24.

Section of Comparative Pediatrics and Nutrition, Department of Veterinary and Animal Science, University of Copenhagen, Copenhagen, Denmark.

Pre-term infants have an immature digestive system predisposing to short- and long-term complications including feeding intolerance, maldigestion and necrotizing enterocolitis (NEC). Optimal feeding strategies are required to promote maturation of the gut including the exocrine pancreas. Little is known about age- and diet-related development of pancreatic exocrine enzymes following pre-term birth. Read More

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