Cell Death Dis 2014 Nov 20;5:e1532. Epub 2014 Nov 20.
1] Research Center for Biomineralization Disorders, and Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea  Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.
Osteoblasts and adipocytes are differentiated from common mesenchymal stem cells (MSCs) in processes which are tightly controlled by various growth factors, signaling molecules, transcriptional factors and microRNAs. Recently, chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) was identified as a critical regulator of MSC fate. In the present study, we aimed to identify some microRNAs (miR), which target COUP-TFII, and to determine the effects on MSCs fate. Read More