43 results match your criteria endosequence putty


Tooth Discoloration Induced by Different Calcium Silicate-Based Cements: A Two-Year Spectrophotometric and Photographic Evaluation in Vitro.

J Clin Pediatr Dent 2021 Apr;45(2):112-116

Objective: Calcium silicate-based cements (CSCs) may lead to coronal staining in young permanent teeth over the time. The purpose of this study was to evaluate and compare the long-term tooth discoloration induced by different CSCs.

Study Design: Ninety freshly-extracted human molars were assigned randomly into 6 groups (n=15/group) according to the CSC used as a pulpotomy material: ProRoot MTA, MTA Angelus, NeoMTA, EndoSequence Putty, Biodentine and Negative control (No cement). Read More

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Effects of pre-mixed hydraulic calcium silicate putties on osteogenic differentiation of human dental pulp stem cells in vitro.

J Dent 2021 05 30;108:103653. Epub 2021 Mar 30.

Department of Endodontics, The Dental College of Georgia, Augusta University, Augusta, GA, USA. Electronic address:

Objectives: An experimental tricalcium silicate and dicalcium silicate-containing endodontic putty has been designed to overcome the issue of reduced shelf life after exposure to atmospheric moisture during repeated opening of the container for clinical retrieval. The present study examined the effects of this experimental hydraulic putty on the mineralogenic characteristics of osteogenic lineage-committed human dental pulp stem cells (hDPSCs), by comparing the cellular responses with a commercially available putty (EndoSequence BC RRM Putty).

Methods: The osteogenic potential of hDPSCs that had been exposed to the putties was examined using quantitative reverse-transcription polymerase chain reaction for osteogenic gene expressions and western blot for osteogenic protein expressions. Read More

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Biomineralization of three calcium silicate-based cements after implantation in rat subcutaneous tissue.

Restor Dent Endod 2021 Feb 2;46(1):e1. Epub 2020 Dec 2.

Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, Canada.

Objectives: The aim of this study was to evaluate the dystrophic mineralization deposits from 3 calcium silicate-based cements (Micro-Mega mineral trioxide aggregate [MM-MTA], Biodentine [BD], and EndoSequence Root Repair Material [ESRRM] putty) over time after subcutaneous implantation into rats.

Materials And Methods: Forty-five silicon tubes containing the tested materials and 15 empty tubes (serving as a control group) were subcutaneously implanted into the backs of 15 Wistar rats. At 1, 4, and 8 weeks after implantation, the animals were euthanized ( = 5 animals/group), and the silicon tubes were removed with the surrounding tissues. Read More

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February 2021

Manoeuvrability and biocompatibility of endodontic tricalcium silicate-based putties.

J Dent 2021 01 19;104:103530. Epub 2020 Nov 19.

Department of Endodontics, The Dental College of Georgia, Augusta University, Augusta, GA, USA. Electronic address:

Objectives: The present study evaluated the indentation depth, storage modulus and biocompatibility of an experimental endodontic putty designed for endodontic perforation repair and direct pulp-capping (NeoPutty). The results were compared with the properties associated with the commercially available EndoSequence BC RRM Putty (ES Putty).

Methods: Indentation depth was measured by a profilometer following indentation with the 1/4 lb Gilmore needle. Read More

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January 2021

Spectrophotometric Analysis of Coronal Tooth Discoloration Induced by Tricalcium Silicate Cements in the Presence of Blood.

J Endod 2020 Dec 17;46(12):1913-1919. Epub 2020 Sep 17.

Department of Endodontics, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania.

Introduction: New tricalcium silicate cements have been shown to induce less coronal discoloration. The purpose of this in vitro study was to evaluate the degree of color change induced by various silicate materials in the presence and absence of blood.

Methods: One hundred human extracted anterior single-canal teeth were sectioned to standardized root lengths, accessed, and instrumented. Read More

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December 2020

Filling ability of three bioceramic root-end filling materials: A micro-computed tomography analysis.

Aust Endod J 2020 Dec 8;46(3):424-431. Epub 2020 Sep 8.

Department of Endodontics, University of Iowa College of Dentistry and Dental Clinics, Iowa City, IA, USA.

This study aimed at evaluating the volume of gaps and voids, and the total porosity percentage of three calcium-silicate-based materials in mandibular molars apicoectomy by Micro-CT analysis. Thirty-three mesial roots of extracted human mandibular molars were instrumented and obturated. The apical 3mm of each root was resected and prepared. Read More

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December 2020

Effect of Hydrogel-Based Antibiotic Intracanal Medicaments on Push-Out Bond Strength.

Eur J Dent 2020 Oct 29;14(4):575-583. Epub 2020 Jul 29.

Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, Indiana, United States.

Objective:  This study aimed to evaluate the effects of typical clinical concentration (1,000 mg/mL), low concentration (1 mg/mL) triple antibiotic pastes (TAP), and double antibiotic pastes (DAP) on the bond strength between various root cements and radicular dentin.

Materials And Methods:  Intact single-rooted human teeth ( = 144) were horizontally decoronated and canals instrumented. The roots were treated for 4 weeks with Ca(OH), 1,000 mg/mL of TAP or DAP, and 1 mg/mL of TAP or DAP. Read More

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October 2020

Morphological and chemical analysis of surface interaction of irrigant-endosequence root repair material.

J Biomed Mater Res B Appl Biomater 2020 11 8;108(8):3383-3392. Epub 2020 Jul 8.

Endodontic Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.

This study aimed to evaluate the characterization of chemical interaction of root canal irrigants on the surface of EndoSequence root repair materials using spectroscopy analysis. Round discs of putty and paste were obtained and immersed in saline, sodium hypochlorite (NaOCl), or chlorhexidine. On the surface of chlorhexidine treated putty, diffuse red pigmentation was detected by Raman analysis and diffuse black pigmentation having unusual needle-like shaped crystals was detected by scanning electron microscopy. Read More

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November 2020

Bioactivity and Physicochemical Properties of Three Calcium Silicate-Based Cements: An In Vitro Study.

Biomed Res Int 2020 22;2020:9576930. Epub 2020 May 22.

Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

Objective: This study evaluated the bioactivity and physicochemical properties of three commercial calcium silicate-based endodontic materials (MTA, EndoSequence Root Repair Material putty, and Biodentine™). . Horizontal sections of 3 mm thickness from 18 root canals of human teeth were subjected to biomechanical preparation with WaveOne Gold large rotary instruments. Read More

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The Response of the Pulp-Dentine Complex, PDL, and Bone to Three Calcium Silicate-Based Cements: A Histological Study in an Animal Rat Model.

Bioinorg Chem Appl 2020 13;2020:9582165. Epub 2020 Apr 13.

Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

Objective: The aim of this study was to histologically examine the tissue reaction of three different calcium silicate cements in the closure of perforations in rat incisor teeth. . An experimental lateral root perforation with pulp exposure was performed in 32 lower incisors of 16 male Wistar albino rats. Read More

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Comparison between iRoot BP Plus (EndoSequence Root Repair Material) and Mineral Trioxide Aggregate as Pulp-capping Agents: A Systematic Review.

J Int Soc Prev Community Dent 2019 Nov-Dec;9(6):542-552. Epub 2019 Nov 13.

Department of General Dentistry, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Introduction: iRoot BP Plus, also known as EndoSequence root repair material (EERM) is a premixed bioceramic thick/putty. According to its instruction manual, iRoot BP Plus is composed of tricalcium silicate, zirconium oxide, tantalum pentoxide, dicalcium silicate, calcium sulfate, calcium phosphate monobasic, and filler agents. This systematic review was carried out to evaluate and present the iRoot BP Plus material as a pulp-capping agent. Read More

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November 2019

Comparative evaluation of the pushout bond strength of two root-end materials: An study.

J Conserv Dent 2019 Jul-Aug;22(4):340-343

Department of Conservative Dentistry and Endodontics, A.B. Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to be University), Mangalore, Karnataka, India.

Aim: The aim of this study is to evaluate the pushout bond strength of two bioceramic materials, two component calcium trisilicate material (biodentine), and premixed calcium trisilicate putty (Endosequence root repair material-fast set putty).

Subjects And Methods: 20 maxillary incisors were used in the study. Apical sections of 3mm were obtained and retro cavities to a depth of 3mm were prepared using a straight fissure bur. Read More

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December 2019

Morphological and Spectroscopic Study of an Apatite Layer Induced by Fast-Set Versus Regular-Set EndoSequence Root Repair Materials.

Materials (Basel) 2019 Nov 8;12(22). Epub 2019 Nov 8.

Endodontic Department, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

This study aimed to evaluate the morphology and chemistry of an apatite layer induced by fast-set versus regular-set EndoSequence root repair materials using spectroscopic analysis. Holes of a 4 mm diameter were created in the root canal dentin, which were filled with the test material. Fetal calf serum was used as the incubation medium, and the samples incubated in deionized water were used as controls. Read More

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November 2019

Shear Bond Comparison between 4 Bioceramic Materials and Dual-cure Composite Resin.

J Endod 2019 Nov 3;45(11):1378-1383. Epub 2019 Sep 3.

Department of Endodontics, Louisiana State University, School of Dentistry, New Orleans, Louisiana.

Introduction: Bioceramic materials have shown biologic and physical properties favorable for regenerative treatment. A key to treatment success is an adequate restoration to prevent microleakage; however, research is limited regarding the bond strength between restorative and bioceramic materials used in regenerative procedures. This study compared the bond strength between 4 bioceramic materials and a dual-cure composite resin. Read More

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November 2019

Induction of Osteogenic Differentiation of Mesenchymal Stem Cells by Bioceramic Root Repair Material.

Materials (Basel) 2019 Jul 19;12(14). Epub 2019 Jul 19.

Stem Cell Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah 23839, Saudi Arabia.

This study aimed to evaluate the osteogenic activity of Endosequence Root Repair Material (ERRM) putty using rat mesenchymal stem cells (MSCs). The extract of set ERRM and ProRoot-mineral trioxide aggregate (MTA) (control) was cocultured with rat MSCs and incubated for one, three, and seven days. The cell viability and proliferation were assessed. Read More

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The effect of different chelating agents on the push-out bond strength of proroot mta and endosequence root repair material.

Eur Oral Res 2019 May 1;53(2):88-93. Epub 2019 May 1.

Sivas Cumhuriyet University, Faculty of Dentistry, Department of Pediatric Dentistry, Sivas,Turkey.

Purpose: This study aimed to evaluate the effects of 17% ethylenediaminetetraacetic acid (EDTA), 7% maleic acid (MA), and 10% citric acid (CA) on the push-out bond strength of ProRooT MTA and Endosequence Root Repair Material (ERRM) putty.

Materials And Methods: Eighty single-rooted extracted human teeth were instrumented to obtain a standardized immature teeth model. Based on the chelating agents tested, the specimens were randomly divided into three experimental groups: Group 1 (17% EDTA), Group 2 (7% MA), Group 3 (10% CA), and Group 4 (Positive Control) (n=20 for each group). Read More

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Effect of Irrigants on the Push-Out Bond Strength of Two Bioceramic Root Repair Materials.

Materials (Basel) 2019 Jun 14;12(12). Epub 2019 Jun 14.

Endodontic Department, Faculty of Dentistry, King Abdulaziz University, Jeddah 22252, Saudi Arabia.

The purpose of this study was to compare different irrigants' effect on two EndoSequence root repair materials' push-out bond strength. Sixty root slices were filled either with EndoSequence premixed fast-set putty or regular-set paste, and then immersed either in sodium hypochlorite, chlorhexidine gluconate, or saline (as control) for 30 min, after which the slices were subjected to the push-out test. The surface structures were evaluated with Scanning Electron Microscopy and Fourier Transform Infrared. Read More

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Molecular Analysis of the Antibacterial Effects of Photodynamic Therapy in Endodontic Surgery: A Case Series.

J Endod 2018 Oct 28;44(10):1593-1597. Epub 2018 Aug 28.

Postgraduation Program in Dentistry, Estácio de Sá University, Duque de Caxias, Rio de Janeiro, Rio de Janeiro, Brazil.

In this case series, bacterial reduction promoted by antimicrobial photodynamic therapy (PDT) used during endodontic surgery was evaluated. Cases were also followed up, and the surgical outcome was reported. The study consisted of 19 teeth with posttreatment apical periodontitis that were consecutively treated by endodontic surgery. Read More

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October 2018

Effect of acidic pH on microhardness and microstructure of theraCal LC, endosequence, mineral trioxide aggregate, and biodentine when used as root repair material.

J Conserv Dent 2018 Jul-Aug;21(4):408-412

Department of Conservative Dentistry and Endodontics, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India.

Introduction: The aim of this study was to investigate the microhardness and microstructural features of newer tricalcium silicate materials: TheraCal LC, mineral trioxide aggregate (MTA), biodentine (BD), and Endosequence Root Repair Material (ERRM) putty, after exposure to acidic environments in comparison with distilled water.

Materials And Methods: A total of 80 extracted single-rooted premolars were collected. All the selected specimens were sectioned vertically, and cavities were prepared on the root surface. Read More

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Evaluation of bioceramics and zirconia-reinforced glass ionomer cement in repair of furcation perforations: An study.

J Conserv Dent 2018 Mar-Apr;21(2):184-189

Department of Conservative Dentistry and Endodontics, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.

Aim: The aim and objective of this study was to evaluate and compare the sealing ability of EndoSequence BC RRM-fast set putty, Proroot mineral trioxide aggregate (MTA), and Zirconomer in the repair of furcal perforation by measuring dye leakage under stereomicroscope.

Methodology: A standard access cavity was made on forty-eight extracted mandibular and maxillary first molars followed by creating a furcal perforation in the center of the pulp chamber by using No. 4 round bur (creating a perforation of 2 mm diameter). Read More

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Effect of 3 Bioceramic Materials on Stem Cells of the Apical Papilla Proliferation and Differentiation Using a Dentin Disk Model.

J Endod 2018 Apr 14;44(4):599-603. Epub 2018 Feb 14.

Department of Endodontics, University of Texas Health Science Center at San Antonio, San Antonio, Texas. Electronic address:

Introduction: There is a complex interaction between biomaterials placed as a coronal barrier with stem cells and dentin in regenerative procedures. In this study, the effect of Biodentine (BD; Septodont, Saint-Maurdes-Fossés, France), Endosequence BC Root Repair Material-Putty (ES; Brasseler, Savannah, GA), Endosequence BC Root Repair Material-Putty Fast set (ES-fast, Brasseler), and ProRoot (Dentsply Tulsa Dental Specialties, Johnson City, TN) mineral trioxide aggregate (MTA) on the viability and differentiation of stem cells of the apical papilla (SCAP) was evaluated using an ex vivo dentin disk model.

Methods: Standardized human dentin disks were treated using an established protocol. Read More

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Effect of Blood Exposure on Push-Out Bond Strength of Four Calcium Silicate Based Cements.

Iran Endod J 2017 ;12(2):196-200

Dental Research Center, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

Introduction: The purpose of this study was to compare the push-out bond strength of white ProRoot Mineral Trioxide Aggregate (MTA), Biodentine, calcium-enriched mixture (CEM) cement and Endosequence Root Repair Material (ERRM) putty after exposure to blood.

Methods And Materials: A total of 96 root dentin slices with a standardized thickness of 1.00±0. Read More

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January 2017

Effect of Sodium Hypochlorite on Push-out Bond Strength of Four Calcium Silicate-based Endodontic Materials when used for repairing Perforations on Human Dentin: An in vitro Evaluation.

Authors:
Sara A Alsubait

J Contemp Dent Pract 2017 Apr 1;18(4):289-294. Epub 2017 Apr 1.

Department of Restorative Dental Science, College of Dentistry King Saud University, Riyadh, Kingdom of Saudi Arabia, e-mail:

Aim: This study aimed to evaluate the push-out bond strength of NeoMTA Plus (NMTA), EndoSequence root repair material fast set putty (ERRMF), biodentine (BD), and ProRoot white mineral trioxide aggregate (PMTA) when used as perforation repair materials after exposure to 2.5% sodium hypochlorite (NaOCl) during the early setting phase.

Materials And Methods: Horizontal midroot sections were prepared from single-rooted human teeth. Read More

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Outcome of Revascularization Procedure: A Retrospective Case Series.

J Endod 2016 Dec 7;42(12):1752-1759. Epub 2016 Oct 7.

Department of Endodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

Introduction: The purpose of this retrospective case series was to investigate the outcome of the revascularization procedure in necrotic immature teeth.

Methods: The residents and faculty members at the University of Pennsylvania endodontic department were invited to submit consecutive revascularization cases treated by them, irrespective of the outcome, during the time period of 2009 to 2012. Twenty-eight of 35 submitted necrotic immature teeth met the inclusion criteria. Read More

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December 2016

A Comparison of the Discoloration Potential for EndoSequence Bioceramic Root Repair Material Fast Set Putty and ProRoot MTA in Human Teeth: An In Vitro Study.

J Esthet Restor Dent 2017 Feb 17;29(1):59-67. Epub 2016 Sep 17.

Dental intern, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

Objective: To compare the discoloration potential of Endosequence Bioceramic Root Repair Material fast set putty (ERRMF) and ProRoot MTA (PMTA) when placed coronally in human extracted teeth over a 4-month period.

Methodology: Forty-eight premolars were sectioned 2 mm below the cementoenamel junction. The pulp chambers were cleaned chemo-mechanically. Read More

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February 2017

In vitro evaluation of different dental materials used for the treatment of extensive cervical root defects using human periodontal cells.

Clin Oral Investig 2017 Apr 14;21(3):753-761. Epub 2016 May 14.

Clinic for Oral, Dental and Maxillofacial Diseases, Department of Conservative Dentistry, Division of Endodontics and Dental Traumatology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

Introduction: Repair materials for extensive cervical root defects may come in direct contact with periodontal tissues. This in vitro study compared the effects of four calcium silicate cements (CSC), one resin-modified glass ionomer cement, and one glass carbomer cement on primary human gingival fibroblasts (HGF), alveolar osteoblasts (HAO), and a human osteoblast cell line (hFOB 1.19). Read More

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In Vitro Cytotoxicity Evaluation of Three Root-End Filling Materials in Human Periodontal Ligament Fibroblasts.

Braz Dent J 2016 Mar-Apr;27(2):187-91

Department of Endodontics, Dental School, Universidad Peruana Cayetano Heredia, Lima, Peru.

The aim of this study was to evaluate in vitro the cytotoxicity on human periodontal ligament fibroblasts of three root-end filling materials: MTA Angelus®, EndoSequence Root Repair Material Putty® and Super EBA®. A primary culture of human periodontal ligament fibroblasts was previously obtained in order to evaluate the cytotoxicity of the three extracts from the root-end filling materials after 2 and 7 days of setting. Serial dilutions of these extracts (1:1, 1:2, 1:4 and 1:8) were evaluated at 1, 3 and 7 days using the methyl-thiazol-tetrazolium (MTT) colorimetric assay. Read More

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Surface microhardness of different thicknesses of a premixed bioceramic material with or without the application of a moist cotton pellet.

Dent Res J (Isfahan) 2016 Jan-Feb;13(1):58-62

Department of Endodontics, Laboratory of Molecular Neuroscience, Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Background: This study was conducted to assess the effect of thickness and hydration condition on the surface microhardness of Endosequence Root Repair Material putty (ERRM; Brasseler USA, Savannah, GA), a premixed bioceramic material.

Materials And Methods: Polymethyl methacrylate cylindrical molds with an internal diameter of 4 mm and three heights of 2, 4, and 6 mm were fabricated. In Group 1 (dry condition), the molds with heights of 2, 4, and 6 mm (10 molds of each) were filled with ERRM. Read More

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Comparative Analysis of Calcium Silicate-based Root Filling Materials Using an Open Apex Model.

J Endod 2016 Apr 27;42(4):654-8. Epub 2016 Feb 27.

Department of Endodontics, Texas A&M University Baylor College of Dentistry, Dallas, Texas.

Introduction: Many new calcium silicate-based root filling materials have emerged in the market; however, their performance in the orthograde obturation of an open apex has not been evaluated. The purpose of this study was to compare the marginal adaptation of ProRoot MTA (Dentsply Tulsa Dental, Tulsa, OK), NeoMTA Plus (Avalon Biomed Inc, Bradenton, FL), and Endosequence BC RRM-Fast Set Putty (BC RRM-FS; Brasseler USA, Savannah, GA) after orthograde placement in roots with open apices.

Methods: Palatal roots of maxillary molars were instrumented to create divergent open apices and divided into 4 groups for orthograde obturation: ProRoot MTA, NeoMTA Plus, BC RRM-FS, and BC RRM-FS + BC Sealer. Read More

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Physical properties and hydration behavior of a fast-setting bioceramic endodontic material.

BMC Oral Health 2016 Feb 20;16:23. Epub 2016 Feb 20.

Division of Endodontics, Department of Oral Biological & Medical Sciences, Faculty of Dentistry, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.

Background: To investigate the physical properties and the hydration behaviour of the fast-setting bioceramic iRoot FS Fast Set Root Repair Material (iRoot FS) and three other endodontic cements.

Methods: iRoot FS, Endosequence Root Repair Material Putty (ERRM Putty), gray and white mineral trioxide aggregate (G-MTA & W-MTA), and intermediate restorative material (IRM) were evaluated. The setting time was measured using ANSI/ADA standards. Read More

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February 2016