426,829 results match your criteria endoscopic procedures


The effects of diabetes mellitus on gastric emptying: A prospective observational cohort study.

J Clin Anesth 2021 Jul 26;75:110463. Epub 2021 Jul 26.

Anesthesiology Institute, Cleveland Clinic, OH, United States; Department of General Anesthesiology, Cleveland Clinic, OH, United States.

Study Objective: Our goal was to evaluate the effect of diabetic severity and duration on preoperative residual gastric volume. Secondarily we compared ultrasonic estimates of residual gastric volume with actual volume determined by aspiration during endoscopy.

Design: This was a prospective, observational cohort study that included adults with a history of diabetes mellitus and/or opioid use scheduled for gastrointestinal endoscopic procedures. Read More

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Intraoperative Time-Out to Promote the Implementation of the Critical View of Safety in Laparoscopic Cholecystectomy: A Video-Based Assessment of 343 Procedures.

J Am Coll Surg 2021 Jul 26. Epub 2021 Jul 26.

ICube, University of Strasbourg, CNRS, IHU Strasbourg, France; IHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France.

Background: The critical view of safety (CVS) is poorly adopted in surgical practices although it is ubiquitously recommended to prevent major bile duct injuries during laparoscopic cholecystectomy (LC). This study aims to investigate whether performing a short intraoperative time out can improve CVS implementation.

Study Design: In this before versus after study, surgeons performing LCs at an academic center were invited to use a 5-second long time out to verify CVS before dividing the cystic duct (5-second rule). Read More

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Reinforcing the valuable role of gastric ultrasound for volume and content assessment: an observational study.

Braz J Anesthesiol 2021 Jul 26. Epub 2021 Jul 26.

University of Aveiro, Mathematics Department, Aveiro, Portugal.

Background: Pulmonary aspiration is one of the most important complications in anesthesiology. Assessment of gastric content by ultrasound is a good method to quantify gastric volume and to determine the risk of intraoperative pulmonary aspiration. The aim of this study is to determine the accuracy of the gastric ultrasonography in the qualitative analysis of gastric content, mainly in the analysis of small amounts of liquid content. Read More

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Presentation, Diagnosis and Management of Subglottic and Tracheal Stenosis During Systemic Inflammatory Diseases.

Chest 2021 Jul 26. Epub 2021 Jul 26.

Department of Internal Medicine, National Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (APHP)-Centre Université Paris (CUP), Paris, France. Electronic address:

Background: Subglottic (SGS) and tracheal stenoses (TS) are characterized by a narrowing of the airways. We aimed to describe characteristics and prognosis of nontraumatic and nontumoral SGS or TS.

Research Question: What are the inflammatory etiologies of subglottic and tracheal stenosis and what are their characteristics and prognosis?

Study Design And Methods: We conducted a multicenter observational retrospective study of patients with neither traumatic nor tumoral SGS or TS. Read More

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Comparison of Long-term Outcomes of Colonic Stenting as a "Bridge to Surgery" and Emergency Surgery in Patients With Left-Sided Malignant Colonic Obstruction.

Ann Coloproctol 2021 Jul 29. Epub 2021 Jul 29.

Surgical Endoscopy Colorectal Division, Department of Surgery, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Purpose: Long-term oncologic outcomes of colonic stenting as a "bridge to surgery" in patients with left-sided malignant colonic obstruction (LMCO) are unclear. This study was performed to compare long-term outcomes of self-expandable metal stent (SEMS) insertion as a bridge to surgery and emergency surgery in patients with acute LMCO.

Methods: This retrospective cohort study included patients with acute LMCO who underwent SEMS insertion as a bridge to surgery or emergency surgery. Read More

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Efficacy of double-balloon enteroscopy-assisted endoscopic balloon dilatation combined with stent deployment for hepaticojejunostomy anastomotic stricture.

Dig Endosc 2021 Jul 29. Epub 2021 Jul 29.

Department of Gastroenterology and Hepatology, Okayama University Hospital, Okayama, Japan.

Background: Hepaticojejunostomy anastomotic stricture (HJAS) is a significant complication of biliary reconstruction surgery. Endoscopic management of HJAS using double-balloon enteroscopy has expanded; however, retrospective reports in this setting are limited. This study aimed to evaluate the efficacy of endoscopic balloon dilatation combined with stent deployment for HJAS. Read More

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Transjugular intrahepatic portosystemic shunt (TIPS) placement at index portal hypertensive decompensation (anticipant TIPS) in cirrhosis and the role of early intervention in variceal bleeding and ascites.

Indian J Gastroenterol 2021 Jul 29. Epub 2021 Jul 29.

Gastroenterology and Advanced G.I. Endoscopy, Ernakulam Medical Center, Kochi 682 028, India.

Background: Transjugular intrahepatic portosystemic shunt (TIPS) placement improves survival in patients with refractory/recurrent acute variceal bleeding (RAVB) and refractory ascites/hydrothorax. Recently, early TIPS was shown to reduce rebleeding and improve survival compared to the conventional TIPS. We aimed to study outcomes in patients with cirrhosis undergoing TIPS at first significant portal hypertensive (PHT) decompensation (termed anticipant TIPS) compared to those undergoing TIPS for recurrent or persistent PHT complications (conventional) and compared the former to matched controls on standard medical management (SMT). Read More

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LINC00324 suppresses apoptosis and autophagy in nasopharyngeal carcinoma through upregulation of PAD4 and activation of the PI3K/AKT signaling pathway.

Cell Biol Toxicol 2021 Jul 28. Epub 2021 Jul 28.

Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuchang District, Wuhan, 430000, Hubei, China.

Background: Nasopharyngeal carcinoma (NPC) has high incidence in Southern China and is derived from the mucosal epithelium of the nasopharynx. Accumulating evidence has revealed that peptidyl arginine deiminase 4 (PAD4) exerts carcinogenic effect on certain cancers. We designed this study to probe the specific role that PAD4 plays in NPC and its molecular mechanism. Read More

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A prospective multicenter study of the magnifying endoscopic evaluation of the invasion depth of superficial esophageal cancers.

Surg Endosc 2021 Jul 28. Epub 2021 Jul 28.

Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, 2-5-1 Shikata, Okayama, 700-8558, Japan.

Background: Treatment strategies for superficial esophageal squamous cell carcinoma (SESCC) are determined mainly on the basis of the invasion depth. The Japan Esophageal Society (JES) developed a simplified magnifying endoscopic classification for estimating the invasion depth of SESCC. We aimed to evaluate its accuracy. Read More

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Epstein-Barr Virus (EBV) acute acalculous cholecystitis in an immunocompromised adult patient: a case report and a literature review of a neglected clinical presentation.

J Prev Med Hyg 2021 Mar 29;62(1):E237-E242. Epub 2021 Apr 29.

University of Padova, Italy - IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.

Primary Epstein-Barr virus (EBV) infection may present with self-limiting abdominal involvement, characterized by hepatitis with mild elevation of aminotransferases, splenomegaly, and rarely with acute acalculous cholecystitis (AAC). Usually, treatment of EBV related AAC is symptomatic, without the need for surgery. Here, we describe a severe case of AAC occurring as the first manifestation of infectious mononucleosis in a young adult woman, receiving treatment with interleukin 6 receptor (IL-6r) inhibitor for rheumatoid arthritis (RA); moreover, we have performed a review of the literature on EBV-related AAC. Read More

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Case Report: Uroenteric Fistula in a Pediatric-en-bloc Kidney Transplant Manifests as Deceptive Watery Diarrhea and Normal Anion Gap Acidosis.

Front Pediatr 2021 12;9:687396. Epub 2021 Jul 12.

Division of Pediatric Nephrology, Department of Pediatrics, University of Miami/Holtz Children's Hospital, Miami, FL, United States.

The diagnosis of a post-surgical uroenteric fistula can be challenging and may be delayed for months after symptoms begin. A normal anion gap metabolic acidosis has been reported in up to 100% of patients after ureterosigmoidostomy, and bladder substitution using small bowel and/or colonic segments. Here, we describe a rare case of a pediatric patient who developed a uroenteric fistula from the transplant ureters into the small bowel, after an en-bloc kidney transplantation resulting in profound acidosis and deceptive watery diarrhea. Read More

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Isolation of lymphocytes from the human gastric mucosa.

World J Methodol 2021 Jul 20;11(4):199-207. Epub 2021 Jul 20.

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

Flow cytometry is widely used for lymphocyte immunophenotyping in clinical settings. However, few studies have applied it for analyzing lymphocytes of the gastric mucosa. This review offers an overview of methodologies for isolating lymphocytes from the human stomach. Read More

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Blowing off steam-Identifying bowel perforation after routine colonoscopy.

Clin Case Rep 2021 Jul 23;9(7):e04515. Epub 2021 Jul 23.

Division of Pulmonary/Critical Care Department of Internal Medicine Michigan State University at Hurley Medical Center Flint MI USA.

Colonoscopy is an effective procedure for colorectal cancer (CRC) screening. Perforation is a rare yet the most severe complication, identified by landmarks-double dolphin, triangle, or double-wall sign signifying air and intracolonic contents leaking into the peritoneal space. Prompt recognition and surgical intervention are imperative to avoid high mortality. Read More

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Clinical management for malignant afferent loop obstruction.

World J Gastrointest Oncol 2021 Jul;13(7):684-692

Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Hyogo, Japan.

Afferent loop obstruction (ALO) is defined as duodenal or jejunal mechanical obstruction at the proximal anastomosis site of a gastrojejunostomy. With advances in chemotherapy, the incidence of malignant ALO is increasing. Malignant ALO can be complicated by ischemia, gangrenous bowel, pancreatitis, and ascending cholangitis. Read More

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Sporadic fundic gland polyps with dysplasia or carcinoma: Clinical and endoscopic characteristics.

World J Gastrointest Oncol 2021 Jul;13(7):662-672

Gastrointestinal Center, Sano Hospital, Kobe 655-0031, Hyogo, Japan.

Fundic gland polyps (FGPs) are the most common gastric polyps and have been regarded as benign lesions with little malignant potential, except in the setting of familial adenomatous polyposis. However, in recent years, the prevalence of FGPs has been increasing along with the widespread and frequent use of proton pump inhibitors (PPIs). To date, several cases of FGPs with dysplasia or carcinoma (FGPD/CAs) have been reported. Read More

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Identification and Validation of the Immune Regulator CXCR4 as a Novel Promising Target for Gastric Cancer.

Front Immunol 2021 12;12:702615. Epub 2021 Jul 12.

Endoscopy Center, Minhang Hospital, Fudan University, Shanghai, China.

Immune checkpoint blockade has attracted a lot of attention in the treatment of human malignant tumors. We are trying to establish a prognostic model of gastric cancer (GC) based on the expression profile of immunoregulatory factor-related genes. Based on the TCGA database, we identified 234 differentially expressed immunoregulatory factors. Read More

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Post-Operative Sleep Endoscopy with Target-Controlled Infusion After Palatopharyngoplasty for Obstructive Sleep Apnea: Anatomical and Polysomnographic Outcomes.

Nat Sci Sleep 2021 20;13:1181-1193. Epub 2021 Jul 20.

Department of Otolaryngology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

Introduction: The findings of drug-induced sleep endoscopy (DISE) are not always correlated with the outcome of upper airway surgery for obstructive sleep apnea (OSA), and whether multilevel surgery is truly required in treating multilevel obstruction identified in preoperative DISE remains an issue. We attempted to compare DISE findings before and after palatopharyngoplasty in patients with OSA because changes in DISE may be beneficial to better understand polysomnographic and anatomical outcomes.

Methods: This was a prospective cohort study for 34 patients with moderate to severe OSA who underwent palatopharyngoplasty at a tertiary care center from 2016 to 2018. Read More

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Gastric schwannoma treated by endoscopic full-thickness resection and endoscopic purse-string suture: A case report.

World J Gastroenterol 2021 Jul;27(25):3940-3947

Departments of Gastroenterology, Institute of Digestive, Southwest Hospital, Army Military Medical University, Chongqing 400038, China.

Background: Schwannomas, also known as neurinomas, are tumors that derive from Schwann cells. Gastrointestinal schwannomas are extremely rare, but the stomach is the most common site. Gastric schwannomas are usually asymptomatic. Read More

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Endoscopic submucosal dissection endoscopic mucosal resection for colorectal polyps: A meta-analysis and meta-regression with single arm analysis.

World J Gastroenterol 2021 Jul;27(25):3925-3939

Department of Medicine, National University Hospital, Singapore 119074, Singapore.

Background: Endoscopic submucosal dissection (ESD) has shown to be effective in management of colorectal neoplasm in the Asian countries, while its implementation in Western countries where endoscopic mucosal resection (EMR) is preferred is still debatable.

Aim: To compare the surgical, histological, and oncological outcomes between ESD and EMR in the treatment of colorectal polyps, with subgroup analysis comparing the efficacy of ESD and EMR between Japan and the rest of the world.

Methods: Embase and Medline databases were searched from inception to October 2020 in accordance with PRISMA guidelines for studies comparing , complete resection, margin involvement, resection time, need for additional surgery, complications, and recurrence rate of ESD with EMR. Read More

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Does endoscopic intervention prevent subsequent gastrointestinal bleeding in patients with left ventricular assist devices? A retrospective study.

World J Gastroenterol 2021 Jul;27(25):3877-3887

Division of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA 19104, United States.

Background: Patients with left ventricular assist devices (LVADs) are at increased risk for recurrent gastrointestinal bleeding (GIB) and repeat endoscopic procedures. We assessed the frequency of endoscopy for GIB in patients with LVADs and the impact of endoscopic intervention on preventing a subsequent GIB.

Aim: To evaluate for an association between endoscopic intervention and subsequent GIB. Read More

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Artificial intelligence in small intestinal diseases: Application and prospects.

World J Gastroenterol 2021 Jul;27(25):3734-3747

Trauma Research Center, The Fourth Medical Center and Medical Innovation Research Division of the Chinese People's Liberation Army General Hospital, Beijing 100048, China.

The small intestine is located in the middle of the gastrointestinal tract, so small intestinal diseases are more difficult to diagnose than other gastrointestinal diseases. However, with the extensive application of artificial intelligence in the field of small intestinal diseases, with its efficient learning capacities and computational power, artificial intelligence plays an important role in the auxiliary diagnosis and prognosis prediction based on the capsule endoscopy and other examination methods, which improves the accuracy of diagnosis and prediction and reduces the workload of doctors. In this review, a comprehensive retrieval was performed on articles published up to October 2020 from PubMed and other databases. Read More

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Eosinophil-Derived Neurotoxin Predicts Response to Proton-Pump Inhibitor Treatment in Pediatric Eosinophilic Esophagitis.

J Pediatr Gastroenterol Nutr 2021 Jul 27. Epub 2021 Jul 27.

Orlando Health Arnold Palmer Hospital for Children, Orlando, FL, USA Mayo Clinic Children's Center, Rochester, MN, USA.

Objectives: There are no tests or patient factors to help predict the best treatment approach for a patient with eosinophilic esophagitis (EoE). The prevalence of PPI responsive EoE in children ranges from 30%-71% with multiple studies showing similar characteristics in responders and non-responders. Eosinophil-derived neurotoxin (EDN), an eosinophilic granule protein, measured in esophageal brushing has been shown to be a viable measure of disease activity in EoE. Read More

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PEITC inhibits the invasion and migration of colorectal cancer cells by blocking TGF-β-induced EMT.

Biomed Pharmacother 2020 Oct 17;130:110743. Epub 2020 Sep 17.

Department of Medicine Oncology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China. Electronic address:

Aim: Tumor metastasis is the leading cause of death in patients with colorectal cancer (CRC), in which epithelial-mesenchymal transition(EMT) plays a vital role. However, the exact mechanisms of this process remain largely unknown. The aim of the present study was to determine the role of phenethyl isothiocyanate (PEITC) in CRC metastasis by regulating EMT. Read More

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October 2020

Corrigendum to 'Physiological and pathophysiological roles of Acidic mammalian chitinase (CHIA) in multiple organs' [Biomed. Pharmacother. 138 (2021) 111465].

Biomed Pharmacother 2021 Jul 14;139:111699. Epub 2021 May 14.

Department of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou Province 563003, China; Digestive Disease Institute of Guizhou Province, Zunyi, Guizhou Province 563003, China; Endoscopy Center, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou Province 563003, China. Electronic address:

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Implementation of European Society of Gastrointestinal Endoscopy (ESGE) recommendations for small-bowel capsule endoscopy into clinical practice: Results of an official ESGE survey.

Endoscopy 2021 Jul 28. Epub 2021 Jul 28.

Pomeranian Medical University, Department of Social Medicine and Public Health, Faculty of Health Science, Szczecin, Poland.

Background:  We aimed to document international practices in small-bowel capsule endoscopy (SBCE), measuring adherence to European Society of Gastrointestinal Endoscopy (ESGE) technical and clinical recommendations.

Methods:  Participants reached through the ESGE contact list completed a 52-item web-based survey.

Results:  217 responded from 47 countries (176 and 41, respectively, from countries with or without a national society affiliated to ESGE). Read More

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Image-enhanced endoscopy for detection of second primary esophageal neoplasms in patients with hypopharyngeal cancer: prevalence, risk factors, and characteristics.

J Chin Med Assoc 2021 Jul 26. Epub 2021 Jul 26.

Department of Otolaryngology, Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, ROC School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC Endoscopy Center for Diagnosis and Treatment, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

Background: Esophageal second primary neoplasms (ESPNs) are common in hypopharyngeal squamous cell carcinoma (HPSCC) patients and are associated with poor prognoses. The effectiveness of image-enhanced endoscopy (IEE) has not been well established.

Methods: We reviewed the patients between April 2016 and April 2018 with HPSCC receiving ESPNs screening via white-light imaging, narrow-band imaging, and Lugol chromoendoscopy. Read More

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Video Consent for Colonoscopy Improves Knowledge Retention and Patient Satisfaction: A Randomized Controlled Study.

J Clin Gastroenterol 2021 Jul 28. Epub 2021 Jul 28.

Department of Gastroenterology, Hepatology, and Nutrition, Digestive Diseases and Surgery Institute Department of Internal Medicine, Community Care Institute, Cleveland Clinic, Cleveland, OH.

Background And Aim: Informed consent for endoscopy is variable across institutions and remains understudied in gastrointestinal endoscopy. This study aims to standardize informed consent for screening and diagnostic colonoscopies with a supplemental video tool that includes the key components of informed consent.

Methods: A video tool was developed that incorporated the key components of informed consent for colonoscopy. Read More

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The Impact of Night-time Emergency Department Presentation on Upper Gastrointestinal Hemorrhage Outcomes.

J Clin Gastroenterol 2021 Jul 28. Epub 2021 Jul 28.

Department of Internal Medicine, St. Luke's Hospital, Chesterfield John T. Milliken Department of Medicine, Division of Gastroenterology, Washington University School of Medicine in Saint Louis, St. Louis, MO Department of Medicine, University of Minnesota, Minneapolis, MN Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, Pittsburgh, PA Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA.

Goals: The aim was to investigate the impact of night-time emergency department (ED) presentation on outcomes of patients admitted for acute upper gastrointestinal hemorrhage (UGIH).

Background: The relationship between time of ED presentation and outcomes of gastrointestinal hemorrhage is unclear.

Study: Using the 2016 and 2017 Florida State Inpatient Databases which provide times of ED arrival, we identified and categorized adults hospitalized for UGIH to daytime (07:00 to 18:59 h) and night-time (19:00 to 06:59 h) based on the time of ED presentation. Read More

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Identifying Predictors of Airway Complications During Conscious Sedation Procedures.

Gastroenterol Nurs 2021 Jul 27. Epub 2021 Jul 27.

Rosemary Bray, DNP, RN, CCRN, CNML, is Senior Director of Nursing, Intensive Care Unit, Gastroenterology Services, Ambulatory Surgery and Nursing Administration, French Hospital Medical Center, San Luis Obispo, California. Herschel Knapp, PhD, MSSW, is Director, Dignity Health Nursing Research Fellowship Program, Southern California Regional Office, Los Angeles.

Conscious sedation procedures are complicated by unanticipated airway compromise and obstruction. The STOP-Bang questionnaire (University of Toronto, 2012) is a validated obstructive sleep apnea screening questionnaire used as a preprocedure evaluation tool to assess a patient's risk for obstructive sleep apnea. The purpose of this study was to determine whether risk factors for obstructive sleep apnea, using the STOP-Bang questionnaire, could predict procedural airway complications in 152 endoscopy patients following conscious sedation. Read More

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Deep Learning-Guided Fiberoptic Raman Spectroscopy Enables Real-Time Diagnosis and Assessment of Nasopharyngeal Carcinoma and Post-treatment Efficacy during Endoscopy.

Anal Chem 2021 Jul 28. Epub 2021 Jul 28.

Optical Bioimaging Laboratory, Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore 117576, Singapore.

In this work, we develop a deep learning-guided fiberoptic Raman diagnostic platform to assess its ability of real-time nasopharyngeal carcinoma (NPC) diagnosis and post-treatment follow-up of NPC patients. The robust Raman diagnostic platform is established using innovative multi-layer Raman-specified convolutional neural networks (RS-CNN) together with simultaneous fingerprint and high-wavenumber spectra acquired within sub-seconds using a fiberoptic Raman endoscopy system. We have acquired a total of 15,354 FP/HW Raman spectra (control: 1761; NPC: 4147; and post-treatment (PT): 9446) from 888 tissue sites of 418 subjects (healthy control: 85; NPC: 82; and PT: 251) during endoscopic examination. Read More

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