486,790 results match your criteria endoscopic


The success of Eso-SPONGE® therapy in the treatment of anastomotic dehiscence after Ivor-Lewis subtotal esophagectomy: A case report.

Int J Surg Case Rep 2021 Oct 18;88:106525. Epub 2021 Oct 18.

Thoracic Surgery Unit, Dipartment of Diagnostic and Specialty Medicine - DIMES of the Alma Mater Studiorum, University of Bologna, G.B. Morgagni - L. Pierantoni Hospital, 34 Carlo Forlanini Street, 47121 Forlì, Italy. Electronic address:

Introduction: Eso-SPONGE® has proved to be an excellent method for the treatment of persistent dehiscence of the intrathoracic esophagogastric anastomosis during the operation of subtotal esophagectomy sec. Ivor Lewis.

Clinical Case Presentation: The case presented is of a 72-year-old patient with esophageal adenocarcinoma (ADK) who underwent sub-total esophagectomy and esophagoplasty sec. Read More

View Article and Full-Text PDF
October 2021

Mind the gap - Small bowel obstruction due to preperitoneal herniation following laparoscopic inguinal hernia repair - A case report.

Int J Surg Case Rep 2021 Oct 18;88:106532. Epub 2021 Oct 18.

Department of Visceral and Transplantation Surgery, University Hospital of Zürich, Zürich, Switzerland; Department of Surgery, Spital Männedorf, Männedorf, Switzerland.

Introduction And Importance: Inguinal hernia repair is a very frequent operation in general and visceral surgery worldwide. The laparo-endoscopic approaches such as TAPP have gained increasing acceptance among specialists and many consider them as standard of care due to perioperative safety and excellent postoperative results. Knowledge of specific complications after minimally invasive inguinal hernia surgery, however, is important for the successful management of these patients. Read More

View Article and Full-Text PDF
October 2021

Mixed neuroendocrine-non-neuroendocrine tumour of pancreas mimicking groove pancreatitis: Case report.

Int J Surg Case Rep 2021 Oct 18;88:106524. Epub 2021 Oct 18.

Department of Gastroenterology, Institute of Postgraduate Medical Education & Research, Kolkata, India.

Introduction: Mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) is a rare tumour of the pancreas which can mimic groove pancreatitis.

Case Report: We present a 49-year-old Indian male presented with constant, dull-aching epigastric pain for last 6 months radiating to back, not associated with jaundice, gastrointestinal bleed, fever or weight loss. He also had history of alcohol abuse for last 15 years. Read More

View Article and Full-Text PDF
October 2021

A case report of allergic fungal rhinosinusitis managed with Dupilumab.

Int J Surg Case Rep 2021 Oct 7;88:106479. Epub 2021 Oct 7.

Section of Allergy/Immunology, Department of Medicine, King Faisal Specialist Hospital and Research Center (KFSHR&RC), Riyadh, Saudi Arabia.

Introduction: Allergic fungal rhinosinusitis (AFRS) is a subtype of chronic rhinosinusitis with nasal polyps. It is characterized by eosinophilic mucin, which results from an inflammatory reaction to non-invasive fungal hyphae in the rhino-sinuses. It is clinically recognizable due to the criteria set by Bent and Kuhn. Read More

View Article and Full-Text PDF
October 2021

Anti-TNFα vs thiopurines for the prevention of postoperative recurrence in Crohn's disease: a meta-analysis of individual participant data.

Clin Gastroenterol Hepatol 2021 Oct 20. Epub 2021 Oct 20.

Erasmus University Medical Center, Department of Gastroenterology and Hepatology, Rotterdam, the Netherlands. Electronic address:

Background & Aims: The superiority of anti-TNFα agents to thiopurines for the prevention of postoperative recurrence of Crohn's disease (CD) after ileocolonic resection remains controversial. In this meta-analysis of individual participant data (IPD-MA), the effect of both strategies was compared and assessed after risk stratification.

Methods: After a systematic literature search, IPD were requested from randomized controlled trials investigating thiopurines and/or anti-TNFα agents after ileocolonic resection. Read More

View Article and Full-Text PDF
October 2021

MEDICAL MANAGEMENT OF CHRONIC RHINOSINUSITIS-YARDSTICK.

Ann Allergy Asthma Immunol 2021 Oct 20. Epub 2021 Oct 20.

Department of Internal Medicine, Division of Immunology/Allergy Section, The University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address:

Chronic rhinosinusitis (CRS) is an inflammatory condition of the paranasal sinuses defined by classic symptoms, imaging findings, and/or endoscopic findings. There are a growing number of emerging pharmacologic therapies being evaluated to treat patients with CRS, some of which have gained indication status in the United States. There have not been updated treatment guidelines published in the United States however since 2014. Read More

View Article and Full-Text PDF
October 2021

Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk.

Gastroenterology 2021 Oct 20. Epub 2021 Oct 20.

Division of Allergy and Immunology, University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center. Electronic address:

Background & Aims: Eosinophilic esophagitis (EoE) can progress to fibrostenosis by unclear mechanisms. Herein, we investigated gene dysregulation in fibrostenotic EoE, its association with clinical parameters and specific pathways, and the functional consequences.

Methods: Esophageal biopsies from subjects with EoE were collected across 11 Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) sites (n = 311) and two independent replication cohorts (n = 83). Read More

View Article and Full-Text PDF
October 2021

TREATMENT OF MYCOBACTERIOSIS CAUSED BY SSP. IN A GROUP OF CAPTIVE LOWLAND TAPIRS ().

J Zoo Wildl Med 2021 Sep;52(3):939-948

National Reference Laboratory for Bovine Tuberculosis, Friedrich-Loeffler Institut/Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, 07743 Jena, Germany.

Tapirs are a taxonomic group with a high susceptibility to mycobacterial diseases. However, successful therapy has only been documented sporadically. Here treatment of mycobacteriosis diagnosed in three, one male and two female, lowland tapirs () in a zoo in Germany is reported. Read More

View Article and Full-Text PDF
September 2021

[Impact of Covid 19 on endoscopy in Germany].

Z Gastroenterol 2021 Oct 22. Epub 2021 Oct 22.

III. Medizinische Klinik - Gastroenterologie und Infektiologie, Universitätsklinikum Augsburg, Augsburg, Germany.

Background: Practices and hospitals are facing great challenges in coping with the COVID-19-pandemic. So far, data on the impact of the pandemic on gastroenterological facilities are lacking, especially on a temporal course. A database is lacking, especially for the outpatient care sector. Read More

View Article and Full-Text PDF
October 2021

Advancing Laryngeal Adductor Reflex Testing Beyond Sensory Threshold Detection.

Dysphagia 2021 Oct 22. Epub 2021 Oct 22.

Department of Otolaryngology - Head and Neck Surgery, University of Missouri School of Medicine, One Hospital Dr. MA314, Columbia, MO, 65212, USA.

Flexible endoscopic evaluation of swallowing with sensory testing (FEESST) is a promising clinical tool to assess airway integrity via the laryngeal adductor reflex (LAR). The current clinical protocol relies on sensory threshold detection, as relatively little is known about the motor response of this sensorimotor airway protective reflex. Here, we focused on characterizing normative LAR motion dynamics in 20 healthy young participants using our prototype high-pressure syringe-based air pulse device and analytic software (VFtrack™) that tracks vocal fold (VF) motion in endoscopic videos. Read More

View Article and Full-Text PDF
October 2021

Organ preservation following short-course radiotherapy for rectal cancer.

BJS Open 2021 Sep;5(5)

Department of Pelvic Cancer, Division of Coloproctology, Karolinska University Hospital, Stockholm, Sweden.

Background: Non-operative management of rectal cancer is increasingly being used in selected patients. Most reports include patients treated with chemoradiotherapy (CRT) before inclusion into a Watch & Wait (W&W) programme. The aim of this study was to report outcomes from a single-centre W&W programme involving a large cohort of patients. Read More

View Article and Full-Text PDF
September 2021

Efficacy and safety of gastric peroral endoscopic myotomy (G-POEM) for refractory gastroparesis: 3-year follow up results.

J Formos Med Assoc 2021 Oct 19. Epub 2021 Oct 19.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, College of Medicine, Taipei, Taiwan.

Background/purpose: Gastroparesis is a common but easily overlooked disease. Gastric peroral endoscopic myotomy (G-POEM) is one of the third-space endoscopy techniques to treat gastroparesis. In this study, we aimed to evaluate the efficacy and safety of G-POEM for patients with refractory gastroparesis. Read More

View Article and Full-Text PDF
October 2021

Near-focus narrow-band imaging for endoscopic assessment of duodenal villi: Making the case more than ever?

Gastrointest Endosc 2021 Oct 19. Epub 2021 Oct 19.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.

View Article and Full-Text PDF
October 2021

Comparison of sampling methods in assessing the microbiome from patients with ulcerative colitis.

BMC Gastroenterol 2021 Oct 22;21(1):396. Epub 2021 Oct 22.

Department of Internal Medicine, Inje University College of Medicine, Busan Paik Hospital, 75 Bokji-ro, Busanjin-gu, Busan, 47392, Korea.

Background: Dysbiosis of ulcerative colitis (UC) has been frequently investigated using readily accessible stool samples. However, stool samples might insufficiently represent the mucosa-associated microbiome status. We hypothesized that luminal contents including loosely adherent luminal bacteria after bowel preparation may be suitable for diagnosing the dysbiosis of UC. Read More

View Article and Full-Text PDF
October 2021

Time trends in the prevalence of infection in patients with peptic ulcer disease: a single-center retrospective study in Shanghai.

J Int Med Res 2021 Oct;49(10):3000605211051167

Department of Gastroenterology and Hepatology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Disease, Key Laboratory of Gastroenterology & Hepatology, Ministry of Health, Shanghai, China.

Objective: The present study aimed to investigate the recent trends in infection associated with peptic ulcer disease in a large population in Shanghai.

Methods: We analyzed the medical records of all patients who had undergone upper gastrointestinal endoscopy (EGD) for uninvestigated dyspepsia at Ren Ji Hospital between 2013 and 2019 to determine the prevalence of infection in patients with peptic ulcers.

Results: Peptic ulcers were found in 40,385 of the 383,413 patients who underwent EGD during the study period. Read More

View Article and Full-Text PDF
October 2021

Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and Cells.

Authors:
Peter Blümler

Cells 2021 Oct 9;10(10). Epub 2021 Oct 9.

Institute of Physics, University of Mainz, Staudingerweg 7, 55099 Mainz, Germany.

The idea of remote magnetic guiding is developed from the underlying physics of a concept that allows for bijective force generation over the inner volume of magnet systems. This concept can equally be implemented by electro- or permanent magnets. Here, permanent magnets are in the focus because they offer many advantages. Read More

View Article and Full-Text PDF
October 2021

Lifestyle, WCRF/AICR Recommendations, and Esophageal Adenocarcinoma Risk: A Systematic Review of the Literature.

Nutrients 2021 Oct 8;13(10). Epub 2021 Oct 8.

School of Medicine, Vita-Salute San Raffaele University, Via Olgettina, 60, 20132 Milan, Italy.

One of the most notable changes in the epidemiology of esophageal cancer (EC) is the rising incidence and prevalence of esophageal adenocarcinoma (EAC) in developed countries. The aim of this systematic review was to collect and summarize all the available evidence regarding lifestyle, diet, and EAC risk. We searched the PubMed and Scopus databases in January 2021 for studies providing information about lifestyle, diet, WCRF/AICR recommendations, and EAC risk; published in English; without a time filter. Read More

View Article and Full-Text PDF
October 2021

Exploring the Advantages of a Hydrolyzed Rice Formula in the Dietary Management of Infants with Cow's Milk Allergy in the Middle East, North Africa, and Pakistan Region.

Nutrients 2021 Sep 28;13(10). Epub 2021 Sep 28.

Pediatric Gastroenterology Department, Mediclinic Airport Road, Abu Dhabi 48481, United Arab Emirates.

Cow's milk allergy (CMA) is the most common food allergy in early childhood, and its prevalence continues to rise. Exclusive breastfeeding is recommended for infants in the first 6 months of life, but this recommendation is poorly adhered to in many parts of the world, including the Middle East, North Africa, and Pakistan (MENAP) region. If the infant is affected by CMA, current guidelines recommend extensively hydrolyzed formulas (eHFs) or amino acid-based formulas (AAFs) in the case of severe symptoms, and hydrolyzed rice formulas (HRFs) where available. Read More

View Article and Full-Text PDF
September 2021

The Role of Contrast-Enhanced Harmonic Endoscopic Ultrasound in Interventional Endoscopic Ultrasound.

Medicina (Kaunas) 2021 Oct 11;57(10). Epub 2021 Oct 11.

Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena Hospitals, AUSL Romagna, 47121 Forlì, Italy.

Over the last decades, contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) has emerged as an important diagnostic tool for the diagnosis and differentiation of several gastrointestinal diseases. The key advantage of CH-EUS is that the influx and washout of contrast in the target lesion can be observed in real time, accurately depicting microvasculature. CH-EUS is established as an evidence-based technique complementary to B-mode EUS to differentiate solid appearing structures, to characterize mass lesions, and to improve the staging of gastrointestinal and pancreatobiliary cancer. Read More

View Article and Full-Text PDF
October 2021

ENT Residents Benefit from a Structured Operation Planning Approach in the Training of Functional Endoscopic Sinus Surgery.

Medicina (Kaunas) 2021 Oct 4;57(10). Epub 2021 Oct 4.

Department of Otorhinolaryngology, University Medical Center Bonn, 53127 Bonn, Germany.

: Preoperative planning utilizing computed tomographies (CT) is of utmost importance in functional endoscopic sinus surgery (FESS). Frequently, no uniform documentation and planning structures are available to residents in training. Consequently, overall completeness and quality of operation planning may vary greatly. Read More

View Article and Full-Text PDF
October 2021

Anemia in Crohn's Disease-The Unseen Face of Inflammatory Bowel Disease.

Medicina (Kaunas) 2021 Sep 30;57(10). Epub 2021 Sep 30.

Medicale I Department "Grigore T. Popa", University of Medicine and Pharmacy, 700111 Iasi, Romania.

: Anemia is the most frequent complication of inflammatory bowel diseases. Clinically, anemia can affect important quality-of-life (QoL) components, such as exercise capacity, cognitive function, and the ability to carry out social activities. The disease activity has a significant impact on QoL, mainly due to clinical manifestations, which are more severe during the periods of disease activity. Read More

View Article and Full-Text PDF
September 2021

EUS and ERCP in the Same Session for Biliary Stones: From Risk Stratification to Treatment Strategy in Different Clinical Conditions.

Medicina (Kaunas) 2021 Sep 25;57(10). Epub 2021 Sep 25.

Gastrointestinal Unit, Department of Medical and Surgical Sciences, Hospital of Imola, University of Bologna, Via Montericco 4, 40026 Imola, BO, Italy.

Endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and stone extraction is the treatment of choice for choledocholithiasis, reaching a successful clearance of the common bile duct (CBD) in up to 90% of the cases. Endoscopic ultrasound (EUS) has the best diagnostic accuracy for CBD stones, its sensitivity and specificity range being 89-94% and 94-95%, respectively. Traditionally seen as two separate entities, the two worlds of EUS and ERCP have recently come together under the new discipline of bilio-pancreatic endoscopy. Read More

View Article and Full-Text PDF
September 2021

Biliopancreatic Endoscopy in Altered Anatomy.

Medicina (Kaunas) 2021 Sep 25;57(10). Epub 2021 Sep 25.

Endoscopy Service, Department of Diagnostic and Therapeutic Services, IRCCS-ISMETT, 90127 Palermo, Italy.

: Anatomical post-surgical alterations of the upper gastrointestinal (GI) tract have always been challenging for performing diagnostic and therapeutic endoscopy, especially when biliopancreatic diseases are involved. Esophagectomy, gastrectomy with various reconstructions and pancreaticoduodenectomy are among the most common surgeries causing upper GI tract alterations. Technological improvements and new methods have increased the endoscopic success rate in these patients, and the literature has been rapidly increasing over the past few years. Read More

View Article and Full-Text PDF
September 2021

Model-Informed Precision Dosing during Infliximab Induction Therapy Reduces Variability in Exposure and Endoscopic Improvement between Patients with Ulcerative Colitis.

Pharmaceutics 2021 Oct 6;13(10). Epub 2021 Oct 6.

Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.

Model-informed precision dosing (MIPD) may be a solution to therapeutic failure of infliximab for patients with ulcerative colitis (UC), as underexposure could be avoided, and the probability of endoscopic improvement (pEI; Mayo endoscopic subscore ≤ 1) could be optimized. To investigate in silico whether this claim has merit, four induction dosing regimens were simulated: 5 mg/kg (label dosing), 10 mg/kg, covariate-based MIPD (fat-free mass, corticosteroid use, and presence of extensive colitis at baseline), and concentration-based MIPD (based on the trough concentration at day 14). Covariate- and concentration-based MIPD were chosen to target the same median area under the infliximab concentration-time curve up to endoscopy at day 84 (AUC), as was predicted from 10 mg/kg dosing. Read More

View Article and Full-Text PDF
October 2021

Challenges in Determining the Role of Microbiome Evolution in Barrett's Esophagus and Progression to Esophageal Adenocarcinoma.

Microorganisms 2021 Sep 22;9(10). Epub 2021 Sep 22.

Division of Biomedical Informatics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.

Esophageal adenocarcinoma (EAC) claims the lives of half of patients within the first year of diagnosis, and its incidence has rapidly increased since the 1970s despite extensive research into etiological factors. The changes in the microbiome within the distal esophagus in modern populations may help explain the growth in cases that other common EAC risk factors together cannot fully explain. The precursor to EAC is Barrett's esophagus (BE), a metaplasia adapted to a reflux-mediated microenvironment that can be challenging to diagnose in patients who do not undergo endoscopic screening. Read More

View Article and Full-Text PDF
September 2021

TRANS-TACE: Prognostic Role of the Transient Hypertransaminasemia after Conventional Chemoembolization for Hepatocellular Carcinoma.

J Pers Med 2021 Oct 17;11(10). Epub 2021 Oct 17.

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40137 Bologna, Italy.

The aim of the present study was to correlate laboratory data and postprocedural parameters after conventional transarterial chemoembolization (cTACE) for hepatocellular carcinoma (HCC) with the radiological response. The study consisted of a retrospective analysis of prospectively collected data from 70 consecutive patients who underwent cTACE. Laboratory parameters were assessed daily after cTACE and compared to pretreatment values. Read More

View Article and Full-Text PDF
October 2021

Flexible Magnifying Endoscopy with Narrow Band Imaging for Diagnosing Uterine Cervical Neoplasms: A Multicenter Prospective Study.

J Clin Med 2021 Oct 16;10(20). Epub 2021 Oct 16.

Department of Gynecology, Kochi Red Cross Hospital, Kochi, 2-13-51 Shinhonmachi, Kochi 780-8562, Japan.

We aimed to investigate the diagnostic ability of magnifying endoscopy with narrow band imaging (ME-NBI) for cervical intraepithelial neoplasia grade 2 or worse (CIN2+). This was a multicenter prospective study. Eligible patients had positive Pap smear results or follow-up high-grade cytology or CIN3 diagnosed in referring hospitals. Read More

View Article and Full-Text PDF
October 2021

Machine Learning Prediction Model for Inflammatory Bowel Disease Based on Laboratory Markers. Working Model in a Discovery Cohort Study.

J Clin Med 2021 Oct 16;10(20). Epub 2021 Oct 16.

Divison of Dietetics, Department of Gastroenterology and Hepatology, Wroclaw Medical University, Borowska 213, 50-556 Wrocław, Poland.

Inflammatory bowel disease (IBD) is a chronic, incurable disease involving the gastrointestinal tract. It is characterized by complex, unclear pathogenesis, increased prevalence worldwide, and a wide spectrum of extraintestinal manifestations and comorbidities. Recognition of IBD remains challenging and delays in disease diagnosis still poses a significant clinical problem as it negatively impacts disease outcome. Read More

View Article and Full-Text PDF
October 2021

Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery.

J Clin Med 2021 Oct 13;10(20). Epub 2021 Oct 13.

Department of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology in Katowice, 41-800 Zabrze, Poland.

Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). Read More

View Article and Full-Text PDF
October 2021

Effect of Endoscopic Sinus Surgery on Eustachian Tube Function in Adult Sinusitis Patients: A Prospective Case-Control Study.

J Clin Med 2021 Oct 13;10(20). Epub 2021 Oct 13.

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Kangnam Sacred Heart Hospital, Hallym University, Seoul 07441, Korea.

The eustachian tube (E-tube) function is known to be related with sinusitis; however, the effect of endoscopic sinus surgery (ESS) on E-tube function is not clearly documented. This study aimed to prospectively evaluate the function of the E-tube by using both subjective and objective tests in adult chronic sinusitis patients undergoing ESS, and to compare with those of the patients without sinusitis. Thirty adult patients who underwent ESS for treatment of chronic sinusitis and another thirty patients without sinusitis who underwent other nasal surgeries (septoplasty, rhinoplasty, or closed reduction) were evaluated and compared for E-tube function before and after three months of their surgeries. Read More

View Article and Full-Text PDF
October 2021