1,885 results match your criteria endometrioma recurrence

Depression, Anxiety, and Correlating Factors in Endometriosis: A Systematic Review and Meta-Analysis.

J Womens Health (Larchmt) 2021 Jun 2. Epub 2021 Jun 2.

Department of Psychiatry and Psychology, MeHNS School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.

Endometriosis stage is not directly related to the burden of symptoms, and recurrence of symptoms occurs frequently. It is suggested that symptoms are associated with psychological distress, as in depression and anxiety disorders. Our aim was to explore the strength of the associations between endometriosis and depression or anxiety and to review correlating factors. Read More

View Article and Full-Text PDF

Clinical and Pathological Significance of Cellular Atypia in Endometriosis.

Medicina (Kaunas) 2021 May 7;57(5). Epub 2021 May 7.

Departament of Obstretics and Gynecology, University of Medicine and Pharmacies, Science and Technology George Emil Palade, 540139 Tîrgu Mureș, Romania.

: To highlight the most frequent localization of ovarian endometriosis, the presence of atypical endometriosis, and recurrences. Retrospective review of 259 patients diagnosed with ovarian endometriosis treated at Tîrgu-Mures Emergency County Hospital, Obstetric Gynecology Clinic, between January 2014 and December 2018. : Data were collected and analyzed for demographics, size of ovarian endometriotic cyst, and recurrences. Read More

View Article and Full-Text PDF

Endometriosis: Etiology, pathobiology, and therapeutic prospects.

Cell 2021 May;184(11):2807-2824

EXPPECT Centre, The University of Edinburgh, Edinburgh Bioquarter, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

Endometriosis is a common condition associated with infertility that causes chronic pain in many, but not all, women. It is defined by the presence of endometrial-like tissue outside the uterus. Although the cause and natural history of the disorder remain uncertain, hormonal, neurological, and immunological factors are all implicated in the mechanisms contributing to development of symptoms. Read More

View Article and Full-Text PDF

Diagnosis and Treatment of Vulvo-Perineal Endometriosis: A Systematic Review.

Front Surg 2021 11;8:637180. Epub 2021 May 11.

Department of Gynecology-Andrology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

To describe the available knowledge on vulvo-perineal endometriosis including its diagnosis, clinical management and recurrence rate. We followed the PRISMA guidelines for Systematic Reviews and our study was prospectively registered with PROSPERO (CRD42020202441). The terms " and " or " were used as keywords. Read More

View Article and Full-Text PDF

Dienogest vs GnRH agonists as postoperative therapy after laparoscopic eradication of deep infiltrating endometriosis with bowel and parametrial surgery: a randomized controlled trial.

Gynecol Endocrinol 2021 May 26:1-4. Epub 2021 May 26.

Ospedale Policlinico San Martino, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, Italy.

Background: The recurrence of deep infiltrating endometriosis (DIE) after its surgical excision is a big problem: postoperative treatment is crucial.

Objective: To compare two postoperative treatments: Dienogest and GnRH agonists.

Design: Prospective Randomized Controlled Trial (RCT). Read More

View Article and Full-Text PDF

The value of long noncoding RNAs for predicting the recurrence of endometriosis: A protocol for meta-analysis and bioinformatics analysis.

Medicine (Baltimore) 2021 May;100(21):e26036

Laboratory of the Key Perinatal Diseases, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education.

Background: As a gynecological disease, endometriosis (EM) seriously endangers the health of women at the age of childbearing and is closely related to long noncoding RNAs (lncRNAs). Current studies have discovered that there are differential expressions of many kinds of lncRNAs in EM. However, whether lncRNAs can be applied as a new marker for the prediction of the recurrence of EM is still controversial. Read More

View Article and Full-Text PDF

Comparison of surgical and oncologic outcomes in patients with clear cell ovarian carcinoma associated with and without endometriosis.

Arch Gynecol Obstet 2021 May 23. Epub 2021 May 23.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Purpose: To compare clinical characteristics, surgical and oncologic outcomes of clear cell ovarian cancer among patients with cancer arising from endometriosis, cancer coexisting with endometriosis, and cancer without endometriosis.

Methods: A retrospective chart review of patients diagnosed with clear cell ovarian cancer during January 1998-March 2013 was performed. All histopathology specimens were reviewed by a gynecologic pathologist and classified into one of the three following endometriosis status groups: arising group, coexisting group, or without group. Read More

View Article and Full-Text PDF

Study on diagnostic values and pathological conditions of serum HGF and CA199 in endometriosis.

Am J Transl Res 2021 15;13(4):2849-2857. Epub 2021 Apr 15.

Department of Pathology, Dongying Second People's Hospital Dongying 257335, Shandong Province, China.

Objective: This study aimed at exploring the diagnostic values and pathological conditions of serum HGF and CA199 in endometriosis (EMT).

Methods: From May 2017 to January 2019, 86 patients with EMT, who were admitted to our hospital, were grouped as Group B, whereas 78 healthy women undergoing physical examinations during the same period were grouped as Group A. Serum HGF and CA199 levels in both groups were detected to analyze their diagnostic values for EMT and their relationships with clinical data. Read More

View Article and Full-Text PDF

Anastrozole and levonorgrestrel-releasing intrauterine device in the treatment of endometriosis: a randomized clinical trial.

BMC Womens Health 2021 05 20;21(1):211. Epub 2021 May 20.

Department/Division of Gynecology, Miguel Hernández University, San Juan Campus, 03550, San Juan, Alicante, Spain.

Background: To study the effectiveness of an aromatase inhibitor (Anastrozole) associated with levonorgestrel-releasing intrauterine device (LNG-IUD, Mirena®) in the treatment of endometriosis.

Methods: Prospective, randomized clinical trial.

Setting: University Hospital (single center). Read More

View Article and Full-Text PDF

Are we better off using multiple endometriosis classifications in imaging and surgery than settle for one universal less than perfect protocol? Review of staging systems in ultrasound, magnetic resonance and surgery.

J Obstet Gynaecol 2021 May 19:1-7. Epub 2021 May 19.

Department of Obstetrics and Gynaecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague 2, Czech Republic.

There are multiple classifications in imaging and surgery of endometriosis and in this article, we offer a review of the main evaluation systems. The International Deep Endometriosis Analysis group consensus is the leading document for ultrasound assessment, while magnetic resonance imaging is guided by the European Society for Urogenital Radiology recommendations on technical protocol. In surgery, the revised American Society for Reproductive Medicine classification is the oldest system, ideally combined with newer classifications, such as Enzian or Endometriosis Fertility Index. Read More

View Article and Full-Text PDF

Outcomes of laparoscopic management of chronic pelvic pain and endometriosis.

J Obstet Gynaecol 2021 May 19:1-7. Epub 2021 May 19.

Department of Obstetrics and Gynecology, Division of Minimally Invasive Gynecologic Surgery, University of Florida, Gainesville, FL, USA.

This study was designed to determine the rates of reoperation following laparoscopic management of endometriosis, with additional aims to examine long-term fertility and quality of life outcomes. This is a retrospective study and a prospective questionnaire of subjects who underwent laparoscopic surgery for pelvic pain and/or endometriosis from 2010 to 2015. The rate of reoperation was 8. Read More

View Article and Full-Text PDF

Role of surgical treatment in endometriosis.

Minerva Obstet Gynecol 2021 Jun;73(3):317-332

Division of Obstetrics and Gynecology, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.

Endometriosis can take one of three forms depending on its clinical presentation and management: endometriotic ovarian cyst (ovarian endometrioma), superficial or peritoneal endometriosis and deep infiltrating endometriosis (DIE).Among them, DIE is considered the most aggressive, and the patient is often affected by more than one type together. The therapeutic methodology should not be influenced by a combination of different types of endometriotic lesion. Read More

View Article and Full-Text PDF

Role of medical treatment of endometriosis.

Minerva Obstet Gynecol 2021 Jun;73(3):304-316

Department of Molecular and Developmental Medicine, Obstetrics and Gynecology, University of Siena, Siena, Italy -

Endometriosis is a chronic benign disease that affects women of reproductive age. Medical therapy is often the first line of management for women with endometriosis in order to ameliorate symptoms or to prevent post-surgical disease recurrence. Currently, there are several medical options for the management of patients with endometriosis and long-term treatments should balance clinical efficacy (controlling pain symptoms and preventing recurrence of disease after surgery) with an acceptable safety-profile. Read More

View Article and Full-Text PDF

Impact of exercise on pain perception in women with endometriosis: A systematic review.

Acta Obstet Gynecol Scand 2021 May 17. Epub 2021 May 17.

Department of Obstetrics and Gynecology, Odense University Hospital, Odense, Denmark.

Introduction: Endometriosis is challenging to treat. It is a painful and chronic inflammatory disorder that impacts up to 10% of women of reproductive age. Despite available surgical and medical treatment options, recurrence of symptoms is common. Read More

View Article and Full-Text PDF

Risk factors for recurrence of deep infiltrating endometriosis after surgical treatment.

J Obstet Gynaecol Res 2021 May 16. Epub 2021 May 16.

School of Medical Sciences, Department of Obstetrics and Gynecology, University of Campinas (Unicamp), Campinas, Brazil.

Aim: To evaluate the frequency of complications and factors associated with the recurrence of endometriosis in women with deep infiltrating endometriosis (DIE) undergoing surgical treatment.

Methods: A retrospective observational cohort study with 72 women who underwent surgery and followed up by DIE at the University of Campinas from 2007 to 2017. The variables analyzed were clinical characteristics, use and type of drug treatment before and after surgery, operative time and complications inherent to the procedure, as well as the recurrence of lesions on imaging. Read More

View Article and Full-Text PDF

Recommendations for Postoperative Surveillance of Pediatric Benign Ovarian Neoplasms.

J Pediatr Adolesc Gynecol 2021 May 11. Epub 2021 May 11.

Division of Pediatric and Adolescent Gynecology, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, OH. Electronic address:

Study Objective: Assess postoperative management of pediatric patients with benign ovarian neoplasms to develop recommendations for postoperative care.

Design: A retrospective cohort study.

Setting: Eight pediatric hospitals in the Midwest. Read More

View Article and Full-Text PDF

Selective oestrogen receptor modulators (SERMs) for endometriosis.

Cochrane Database Syst Rev 2021 May 11;5:CD011169. Epub 2021 May 11.

Isala Hospitals Zwolle, Zwolle, Netherlands.

Background: Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. This chronic and recurring condition occurs in women of reproductive age. It is a common cause of pain or infertility and can cause non-specific symptoms such as lower back pain, dyspareunia (pain during or after intercourse), and dysmenorrhoea (menstrual pain). Read More

View Article and Full-Text PDF

Dienogest as a Maintenance Treatment for Endometriosis Following Surgery: A Systematic Review and Meta-Analysis.

Front Med (Lausanne) 2021 7;8:652505. Epub 2021 Apr 7.

Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, China.

This study aimed to comprehensively assess the value of Dienogest (DNG) as a maintenance treatment following conservative surgery for endometriosis in terms of the outcomes of disease and pregnancy. We searched for relevant studies and trials up to November 2020 from PubMed, Cochrane Library, Medline, and EMBASE databases as well as the Web of Science. Patients who received DNG maintenance treatment were compared to those who received other treatments (OT), including the levonorgestrel-releasing intrauterine system (LNG-IUS) and gonadotropin-releasing hormone analogs (GnRH-a), or non-treatment (NT). Read More

View Article and Full-Text PDF

Long-term follow-up of endometriosis surgery in Ontario: a population-based cohort study.

Am J Obstet Gynecol 2021 Apr 21. Epub 2021 Apr 21.

Department of Obstetrics and Gynaecology, Queen's University, Kingston Health Sciences Centre, Kingston, Ontario, Canada; Institute for Clinical Evaluative Sciences, Queen's University, Kingston, Ontario, Canada.

Background: Endometriosis is a chronic gynecological disease affecting approximately 10% of reproductive aged females and leads to decreased quality of life and productivity. Despite effective medical options, many women do require surgery for endometriosis. There is limited literature examining long term outcomes of endometriosis surgery. Read More

View Article and Full-Text PDF

Surgical management of diaphragmatic and thoracic endometriosis': A French multicentric descriptive study.

J Gynecol Obstet Hum Reprod 2021 Apr 20;50(8):102147. Epub 2021 Apr 20.

Department of gynecology, Croix Rousse University Hospital, Hospices civils de Lyon (HCL), 103 Grande Rue de la Croix-Rousse, 69004 Lyon, France. Electronic address:

Introduction: Surgical management of Diaphragmatic and thoracic endometriosis (DTE) is still controversial, a thoracic or an abdominal approach can be proposed.

Methods: We conducted a multicentric retrospective study in 8 thoracic, gynecology or digestive surgery units in 5 French university hospitals. The main objective was to review the current management of DTE. Read More

View Article and Full-Text PDF

Endometriosis-Related Pleural Effusion: A Case Report and a PRISMA-Compliant Systematic Review.

Front Med (Lausanne) 2021 30;8:631048. Epub 2021 Mar 30.

Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.

Endometriosis-related pleural effusion (PE) is a relatively rare but treatable cause of bloody PE. The clinical characteristics and outcome of patients with endometriosis-related PE remain unknown. We present a case of endometriosis-related PE diagnosed on pleural fluid cytology. Read More

View Article and Full-Text PDF

Abdominal wall endometriosis: a case report.

J Surg Case Rep 2021 Apr 6;2021(4):rjab055. Epub 2021 Apr 6.

Department of Surgery, University Hospital of Ioannina, Ioannina, Greece.

Abdominal wall endometriosis has an incidence of 0.3-1% of extrapelvic disease. Α 48-year-old female appeared in the emergency department with cellulitis in a lower midline incision. Read More

View Article and Full-Text PDF

Perineal endometriosis: a rare case of a unique sizeable nodule.

Pan Afr Med J 2021 18;38:47. Epub 2021 Jan 18.

University of Medicine of Sfax, Department of Gynecology and Obstetrics, Hedi Chaker Hospital, 3029, Sfax, Tunisia.

Endometriosis is the presence of endometrial tissue in abnormal locations outside the uterine cavity. These locations are usually the ovaries, the peritoneum, and the uterine ligaments. Less frequently, the endometrial tissue can affect the perineum especially after surgical procedures or obstetric lesions. Read More

View Article and Full-Text PDF

Thoracic endometriosis: a case report and review of the literature.

Ann Palliat Med 2021 Mar;10(3):3500-3503

Department of Thoracic Surgery, The Affiliated Hospital of Zunyi Medical University, Guizhou, China.

Thoracic endometriosis is characterized by the presence of normal functioning endometrial tissues in normal pleural, diaphragm, or lung parenchyma, and main clinical symptoms include pneumothorax, menstrual hemothorax, menstrual hemoptysis, and pulmonary nodules. Chest X-ray (CXR), computed tomography (CT), magnetic resonance imaging (MRI), bronchoscopy, and surgical biopsy could be applied to the diagnosis of TE. Both drug therapy and surgical treatment were widely used to treat this disease, but no theory was used to guide the choice of treatment options. Read More

View Article and Full-Text PDF

Long-Term Medical Therapy after Laparoscopic Excision of Ovarian Endometriomas: Can We Reduce and Predict the Risk of Recurrence?

Gynecol Obstet Invest 2021 13;86(1-2):170-176. Epub 2021 Apr 13.

Gynecology and Human Reproduction Physiopathology, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Objectives: Up to 32% of women experience anatomic recurrence after conservative surgery for endometriomas, while pain recurs in 10-40% of cases. Long-term postoperative hormonal therapy is recommended to prevent disease recurrence. We evaluated the efficacy of long-term therapy with estroprogestins (EPs) or progestins (Ps) in preventing endometrioma recurrence, as identifiable cysts and subjective symptoms, after laparoscopic excision. Read More

View Article and Full-Text PDF

Primary inguinal subcutaneous endometriosis accompanied with an inguinal hernia: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25460

Department of Obstetrics and Gynecology.

Rationale: We report a case with inguinal subcutaneous endometriosis without typical cyclic dysmenorrhea and accompanied with a hernia sac treated with resection of the tumor and herniorrhaphy.

Patient Concerns: A 40-year-old woman had a painless enlarged inguinal nodule for 3 months.

Diagnoses: Subcutaneous endometriosis accompanied with a hernia sac. Read More

View Article and Full-Text PDF

Clear-cell carcinoma originating from cesarean section scar: two case reports.

J Med Case Rep 2021 Apr 3;15(1):146. Epub 2021 Apr 3.

University Hospital Schleswig-Holstein, Campus Kiel, Kiel School of Gynaecological Endoscopy, Arnold-Heller-Str. 3, Haus 24, 24105, Kiel, Germany.

Background: Clear-cell carcinoma arising from the surgical cesarean section scar is very infrequent. The present study reports two patients with clear-cell carcinoma arising from an abdominal wall scar 20 and 23 years after their last cesarean section.

Case Presentation: Both Iranian patients had prior cesarean sections nearly 20 years earlier. Read More

View Article and Full-Text PDF

Assisted reproductive technology for women with endometriosis, a clinically oriented review.

Curr Opin Obstet Gynecol 2021 Jun;33(3):225-231

Department of Obstetrics and Gynecology, Istanbul University Istanbul School of Medicine, Istanbul, Turkish Republic.

Purpose Of Review: To discuss optimal management of an assisted reproductive technology (ART) cycle in women with endometriosis.

Recent Findings: New studies involving euploid embryo transfers provide more insight on the etiology of endometriosis-associated infertility. Oocyte competence to reach live birth seems unlikely to be affected by the disease. Read More

View Article and Full-Text PDF

Scar endometriosis: not a rare cause for a painful scar.

Clin Ter 2021 Mar;172(2):129-133

Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo, Palermo.

Conclusion: High suspicion of scar endometriosis are painful no-dule in the abdominal scar. Wide surgical excision is the treatment of choice.

Introduction: Endometriosis has been described as the presence of endometrial tissue outside uterine cavity. Read More

View Article and Full-Text PDF

Providing new insights into the endometriosisassociated cancer arising in episiotomy scars.

Ginekol Pol 2021 10;92(3):220-225. Epub 2021 Mar 10.

Universitary Clinic of Gynecology, Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, Coimbra, Portugal.

Endometriosis-associated malignancy in an episiotomy scar is rare. The predictive factors are poorly understood as are the mechanisms and pathways associated with implantation and malignant transformation. In this study we describe the cases reported in the literature of malignancies arising in endometriosis foci of an episiotomy scar. Read More

View Article and Full-Text PDF