357,012 results match your criteria emergency department

Prenatal diagnosis and molecular cytogenetic characterization of inherited chromosome 2q11.1q11.2 microduplication with fetal intrauterine growth retardation.

Taiwan J Obstet Gynecol 2022 Jul;61(4):726-727

Department of Endocrinology, Wuhan Hankou Hospital, Wuhan, Hubei, PR China. Electronic address:

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Ultrasonographic findings of placental abruption observed on superb microvascular imaging.

Taiwan J Obstet Gynecol 2022 Jul;61(4):713-716

Department of Obstetrics and Gynecology, St. Marianna University School of Medicine, Kawasaki, Japan.

Objective: To demonstrate ultrasound pathological findings of placental abruption (PA) detected using a new Doppler method: superb microvascular imaging (SMI).

Case Report: The patient was a pregnant woman with dark brown vaginal discharge at 32 + 4 weeks of gestation. Conventional ultrasound revealed an exophytic heterogeneous area measuring 3 cm, between the placenta and myometrium. Read More

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Timing of Cow's Milk Protein Introduction and Childhood Adverse Reactions to Cow's Milk.

J Allergy Clin Immunol Pract 2022 Jun 29. Epub 2022 Jun 29.

Division of Gastroenterology/Nutrition, Department of Pediatrics, University of Massachusetts Medical School; Pediatric Gastroenterology, UMass Memorial Medical Center.

Background: Current guidelines emphasize early introduction to potentially allergenic foods, but the optimal timing, amount and exposure routes for foods other than peanut are not well-established. Cow's milk is often the first allergenic food introduced through infant formulas.

Objective: We examined timing of cow's milk protein introduction (CMPI), including interaction with formula supplementation after delivery, in relation to reported cow's milk adverse reactions (CMARs), throughout childhood. Read More

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Unmanned aerial vehicles (UAVs) as a tool for hazard assessment: The 2021 eruption of Cumbre Vieja volcano, La Palma Island (Spain).

Sci Total Environ 2022 Jun 29:157092. Epub 2022 Jun 29.

Department of Ecology and Coastal Management, Institute of Marine Sciences of Andalusia (ICMAN), Spanish National Research Council (CSIC), 11510 Puerto Real, Spain.

Monitoring for assessment of natural disasters, such as volcanic eruptions, presents a methodological challenge for the scientific community. Here, we present Unmanned Aerial Vehicles (UAVs) as a feasible, precise, rapid and safe tool for real time monitoring of the impacts of a volcanic event during the Cumbre Vieja eruption on La Palma Island, Spain (2021). UAV surveys with optical RGB (Red-Green-Blue), thermal and multispectral sensors, and a water sampling device, were carried out in different areas affected by the lava flow, including the upper volcanic edifice and the lava delta formed on the coastal fringe of the island. Read More

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Emergency department utilization by patients with bipolar disorder: a national population-based study.

J Affect Disord 2022 Jun 29. Epub 2022 Jun 29.

Department of Psychiatry, Meharry Medical College, Nashville, TN, USA.

Background: There is a scarcity of national United States (US) data on emergency department (ED) utilization of patients with bipolar disorder (BD). This study aims to determine the most common reasons for ED visits of patients with BD, and baseline characteristics of patients who present due to BD.

Methods: We obtained data from the Nationwide Emergency Department Sample (NEDS), the largest all-payer ED database in the US. Read More

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Aberrant mitochondrial DNA methylation and declined pulmonary function in a population with polycyclic aromatic hydrocarbon composition in particulate matter.

Environ Res 2022 Jun 29:113797. Epub 2022 Jun 29.

Key Laboratory of Chemical Safety and Health, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China. Electronic address:

Air pollution exposure has been found to be associated with epigenetic modification of the mitochondrial genome, which could subsequently induce adverse health outcomes. However, very limited studies exist regarding the association between fine particulate matter (PM) exposure and pulmonary function at the molecular level of mitochondrial epigenetic changes. This study aimed to investigate the association of platelet mitochondrial DNA (mtDNA) methylation with occupational PM exposure and pulmonary function. Read More

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The AusPollen partnership project: Allergenic airborne grass pollen seasonality and magnitude across temperate and subtropical eastern Australia, 2016-2020.

Environ Res 2022 Jun 29:113762. Epub 2022 Jun 29.

Department of Earth and Environmental Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, New South Wales, 2109, Australia.

Background: Allergic rhinitis affects half a billion people globally, including a fifth of the Australian population. As the foremost outdoor allergen source, ambient grass pollen exposure is likely to be altered by climate change. The AusPollen Partnership aimed to standardize pollen monitoring and examine broad-scale biogeographical and meteorological factors influencing interannual variation in seasonality of grass pollen aerobiology in Australia. Read More

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Outcomes of gynecological cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-GO Cancer study.

Am J Obstet Gynecol 2022 Jun 29. Epub 2022 Jun 29.

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom. Electronic address:

Background: The CovidSurg-Cancer consortium aimed to explore the impact of COVID-19 in surgical patients and services for solid cancers at the start of the pandemic. The CovidSurg-GO Cancer subgroup was particularly concerned about the magnitude of adverse outcomes caused by the disrupted surgical gynecological cancer care during the COVID-19 pandemic, which is currently unclear.

Objective: To evaluate the changes in care and short-term outcomes of surgical patients with gynecological cancers during the COVID-19 pandemic. Read More

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Deploying a Novel Custom Mobile Application for STEMI Activation and Transfer in a Large Healthcare System to Improve Cross-Team Workflow. STEMIcathAID Implementation Project.

Am Heart J 2022 Jun 29. Epub 2022 Jun 29.

The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

Background: ST-segment elevation myocardial infarction (STEMI) is a high-risk patient medical emergency. We developed a secure mobile application, STEMIcathAID, to optimize care for STEMI patients by providing a digital platform for communication between the STEMI care team members, EKG transmission, cardiac catherization laboratory (cath lab) activation and ambulance tracking. The aim of this report is to describe the implementation of the app into the current STEMI workflow in preparation for a pilot project employing the app for inter-hospital STEMI transfer. Read More

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Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial.

Lancet Haematol 2022 Jun 29. Epub 2022 Jun 29.

Department of Angiology, University Hospital Zurich, Zurich, Switzerland; University of Zurich, Zurich, Switzerland.

Background: COVID-19 is a viral prothrombotic respiratory infection. Heparins exert antithrombotic and anti-inflammatory effects, and might have antiviral properties. We aimed to investigate whether thromboprophylaxis with enoxaparin would prevent untoward hospitalisation and death in symptomatic, but clinically stable outpatients with COVID-19. Read More

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The effectiveness of intensive home treatment as a substitute for hospital admission in acute psychiatric crisis resolution in the Netherlands: a two-centre Zelen double-consent randomised controlled trial.

Lancet Psychiatry 2022 Jun 29. Epub 2022 Jun 29.

Department of Research, Arkin, Amsterdam, Netherlands; Vrije Universiteit Department Clinical Psychology, Amsterdam, The Netherlands.

Background: Although de-institutionalisation has been underway for decades, admission to hospital followed by low-intensity outpatient care remains the usual treatment for patients with an acute psychiatric crisis. Intensive home treatment has been developed for patients in a severe psychiatric crisis as an alternative to inpatient care. This study aimed to evaluate the potential of intensive home treatment to reduce bed-days and its clinical effectiveness compared with treatment as usual. Read More

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Outcomes After Transfer of Pediatric Trauma Patients: Does Everyone Need to Visit the Trauma Bay?

J Surg Res 2022 Jun 29;279:164-169. Epub 2022 Jun 29.

Department of Surgery, Valley Children's Hospital, Madera, California. Electronic address:

Introduction: Critically injured children and teens often present to adult trauma centers or nontrauma facilities prior to transfer to a pediatric trauma center. For pediatric patients wanting transfer to the intensive care unit (ICU), there is little data to guide which can be safely transferred directly to the unit, and which should be evaluated first in the trauma bay.

Methods: We used our institutional trauma registry to evaluate transferred trauma patients over a three year period. Read More

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Methyl butyrate attenuates concanavalin A-induced autoimmune hepatitis by inhibiting Th1-cell activation and homing to the liver.

Cell Immunol 2022 Jun 24;378:104575. Epub 2022 Jun 24.

Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, 200040, China. Electronic address:

Con A-induced hepatitis is the most commonly used animal model for simulating autoimmune hepatitis (AIH). In this study, we investigated whether methyl butyrate (MB) alleviates Con A-induced hepatitis and how it affects Con A-stimulated lymphocytes. MB improves liver function in AIH mice, reducing the expression of several inflammatory cytokines and Th1 cell-associated chemokines in the liver, while significantly inhibiting toll-like receptor signaling pathway. Read More

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Electrocardiogram changes in pediatric patients with myocarditis.

Am J Emerg Med 2022 Jun 17;59:49-53. Epub 2022 Jun 17.

Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.

Background: It is traditionally taught that pediatric patients with myocarditis almost always have an abnormal electrocardiogram (ECG) at presentation. However, there has never been a study to objectively evaluate ECG changes in pediatric myocarditis patients compared to healthy controls or explore if specific ECG changes correlate with clinical outcomes.

Methods: Pediatric patients diagnosed with acute myocarditis were age and sex matched 1:2 with healthy controls in this retrospective case-control study spanning a seven-year period. Read More

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Emergency department-to-community care transition barriers: A qualitative study of older adults.

J Am Geriatr Soc 2022 Jul 2. Epub 2022 Jul 2.

Department of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

Background: Over one-half of older adults are discharged to the community after emergency department (ED) visits, and studies have shown there is increased risk of adverse health outcomes in the immediate post-discharge period. Understanding the experiences of older adults during ED-to-community care transitions has the potential to improve geriatric emergency clinical care and inform intervention development. We therefore sought to assess barriers experienced by older adults during ED-to-community care transitions. Read More

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Retrospective analysis and risk of progression of partial anterior cruciate ligament injuries in a young population.

Arch Orthop Trauma Surg 2022 Jul 2. Epub 2022 Jul 2.

Department of Trauma and Emergency, Base Hospital, Guwahati, Assam, 781029, India.

Background: The anterior cruciate ligament (ACL) is a common knee ligament injury. Partial ACL tears are common, and at least 10-27% of isolated ACL tears are diagnosed as partial tears. Patients with partial tears have high risk of progression of tears to complete tears, which may require surgical reconstruction. Read More

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Requirement of preoperative blood typing for cholecystectomy and appendectomy: a systematic review.

Langenbecks Arch Surg 2022 Jul 2. Epub 2022 Jul 2.

Department of General Surgery, Chelsea and Westminster Hospital, 369 Fulham Road, London, SW10 9NH, UK.

Purpose: Blood typing, or group and save (G&S) testing, is commonly performed prior to cholecystectomy and appendectomy in many hospitals. In order to determine whether G&S testing is required prior to these procedures, we set out to evaluate the relevant literature and associated rates of perioperative blood transfusion.

Methods: Studies from January 1990 to June 2021 assessing the requirement of preoperative G&S testing for elective or emergency cholecystectomy and appendectomy were retrieved from MEDLINE, EMBASE and CINAHL databases. Read More

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Emilia-Romagna Surgical Colorectal Cancer Audit (ESCA): a value-based healthcare retro-prospective study to measure and improve the quality of surgical care in colorectal cancer.

Int J Colorectal Dis 2022 Jul 2. Epub 2022 Jul 2.

Healthcare Administration, AUSL of Romagna, Ravenna, Italy.

Purpose: Surgery is the main treatment for non-metastatic colorectal cancer. Despite huge improvements in perioperative care, colorectal surgery is still associated with a significant burden of postoperative complications and ultimately costs for healthcare organizations. Systematic clinical auditing activity has already proven to be effective in measuring and improving clinical outcomes, and for this reason, we decided to evaluate its impact in a large area of northern Italy. Read More

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Severe asthma and personalized approach in the choice of biologic.

Curr Opin Allergy Clin Immunol 2022 Jul 4. Epub 2022 Jul 4.

IRCCS Humanitas Research Hospital.

Purpose Of Review: Severe asthma requires intensive pharmacological treatment to achieve disease control. Oral corticosteroids are effective, but their use is burdened with important side effects. Biologics targeting the specific inflammatory pathways underpinning the disease have been shown to be effective but not all patients respond equally well. Read More

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An Aesop's Fable in Dermatology: When the Fox Doesn't Reach the Grapes… Maybe He Is Taking a Sunbath.

Skinmed 2022 30;20(3):232-238. Epub 2022 Jun 30.

Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.

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"The Raven Himself Is Hoarse:" fungemia manifesting as an eschar.

Skinmed 2022 30;20(3):213-214. Epub 2022 Jun 30.

Department of Dermatology, Baylor College of Medicine, Houston, TX;

A 65-year-old man with diabetes, end-stage renal disease on hemodialysis, coronary artery disease, and a prosthetic aortic valve. He presented to the emergency department with hypothermia (96.6°F), several weeks of anorexia and chills, and bilateral lower extremity tissue necrosis with erythema and edema (Figure 1A). Read More

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Pregnancy in a patient with caudal regression syndrome following continent bladder reconstruction.

J Obstet Gynaecol Res 2022 Jul 2. Epub 2022 Jul 2.

Department of Obstetrics and Gynecology, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Caudal regression syndrome (CRS) is rare congenital malformation, which is characterized by abnormal development of the lower end of the spine and complicated with neurodevelopmental disorders of vesico-rectal functions and the lower extremities. We report the case of a woman with CRS who became pregnant and gave birth following continent bladder reconstruction (CBR) for intractable urinary incontinence. A 25-year-old primigravida woman with CRS became pregnant naturally and was referred to our department. Read More

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The Incidence of Multisystem Inflammatory syndrome in a Pediatric Emergency Department.

Acta Paediatr 2022 Jul 2. Epub 2022 Jul 2.

Paediatric Emergency Room and Emergency Medicine, Gaslini Children Hospital, Istituto Giannina Gaslini, IRCCS, Genoa, Italy.

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A Simulation Study Using a Quality Cardiopulmonary Resuscitation Medical Manikin to Evaluate the Effects of Using Personal Protective Equipment on Performance of Emergency Resuscitation by Medical Students from the University of Silesia, Katowice, Poland and Non-Medical Personnel.

Med Sci Monit 2022 Jul 2;28:e936844. Epub 2022 Jul 2.

Student Scientific Society at The Department of Emergency Medicine, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland.

BACKGROUND During the Coronavirus disease 2019 (COVID-19) pandemic, personal protective equipment (PPE) is used during medical resuscitation aerosol-generating procedures (AGP). This simulation study aimed to evaluate the effects of PPE on the performance of emergency resuscitation by medical students from the University of Silesia, Katowice, Poland and non-medical personnel, and used a quality cardiopulmonary resuscitation (Q-CPR) medical manikin. MATERIAL AND METHODS A simulation study was conducted using the Resusci Anne quality cardiopulmonary resuscitation (Q-CPR) medical manikin (Laerdal Medical AS, Norway). Read More

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Micro RNA 200a contributes to the smooth muscle cells growth in aged-related erectile dysfunction via regulating Rho/ROCK pathway.

Lulu Lou Wei Zheng

Andrologia 2022 Jul 1:e14503. Epub 2022 Jul 1.

Health Management Center, Department of Infectious Diseases, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, People's Republic of China.

Aged-related erectile dysfunction (A-ED) is generally regarded as degeneration of penile erectile tissue due to age, male hormone deficiency and concomitant cardiovascular disease. Current pathological studies of A-ED are still limited. In this study, aged rats were divided into AE group (aged rats with ED) and YN group (young normal rats) for evaluating the roles of miRNA-200a and RhoA/ROCK signalling pathway in A-ED. Read More

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Initial presentation for acute low back pain: is early physical therapy associated with healthcare utilization and spending? A retrospective review of a National Database.

BMC Health Serv Res 2022 Jul 2;22(1):851. Epub 2022 Jul 2.

Department of Orthopaedic Surgery, The Johns Hopkins University, 601 N. Caroline Street, JHOC 5223, Baltimore, MD, 21287, USA.

Background: Early initiation of physical therapy (PT) has been associated with lower healthcare costs and utilization; however, these studies have been limited to single institutions or healthcare systems. Our goal was to assess healthcare utilization and spending among patients who present for the first time with low back pain (LBP), according to whether they received early physical therapy (PT), using a large, nationwide sample; and geographic variation in rates of early PT and 30-day LBP-related spending.

Methods: Using the Truven MarketScan database, we identified nearly 980,000 US adults ages 18-64 years who initially presented with acute LBP from 2010 through 2014 and did not have nonmusculoskeletal causes of LBP. Read More

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Disaster response among hospital nurses dispatched to evacuation centers after the Great East Japan Earthquake: a thematic analysis.

BMC Health Serv Res 2022 Jul 1;22(1):848. Epub 2022 Jul 1.

Department of Radiation Health Management, Fukushima Medical University School of Medicine, Fukushima, Japan.

Background: Disaster relief operations involve a variety of components of healthcare efforts. The post-disaster recovery is a key component of hospital preparedness. This study aimed to investigate the role of hospital nurses in the disaster area and their challenges during the relief efforts after the Great East Japan Earthquake in 2011. Read More

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Decision support-tools for early detection of infection in older people (aged> 65 years): a scoping review.

BMC Geriatr 2022 Jul 1;22(1):552. Epub 2022 Jul 1.

Department of Nursing and Midwifery, University of the Highlands and Islands, Inverness, IV2 3JH, UK.

Background: Infection is more frequent, and serious in people aged > 65 as they experience non-specific signs and symptoms delaying diagnosis and prompt treatment. Monitoring signs and symptoms using decision support tools (DST) is one approach that could help improve early detection ensuring timely treatment and effective care.

Objective: To identify and analyse decision support tools available to support detection of infection in older people (> 65 years). Read More

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Preoperative frailty and chronic pain after cardiac surgery: a prospective observational study.

BMC Anesthesiol 2022 Jul 1;22(1):201. Epub 2022 Jul 1.

Department of Anesthesiology, Intensive Care, and Pain Medicine, St. Antonius Hospital, Koekoekslaan 1, 3430 EM, Nieuwegein, The Netherlands.

Background: Chronic pain after cardiac surgery, whether or not related to the operation, is common and has negative impact on health related quality of life (HRQL). Frailty is a risk factor for adverse surgical outcomes, but its relationship with chronic pain after cardiac surgery is unknown. This study aimed to address the association between frailty and chronic pain following cardiac surgery. Read More

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