Front Microbiol 2021 22;12:649757. Epub 2021 Apr 22.
Department of Pharmacy, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
The increasing emergence of bacterial strains with high VAN MICs (BS ), such as , , , , and , results in growing concern that VAN is not effective against these isolates. Due to the limited data on VAN against BS and the application limits of drugs currently considered to be effective for BS , exploration of "new usages for old drugs" is reasonable to improve and maximize the efficacy of existing antibiotics. This study aimed to construct a novel dosing strategy to mine the competence of VAN in the management of BS infections. Read More