Sci Rep 2020 10 16;10(1):17584. Epub 2020 Oct 16.
Proteomic and Genetic Toxicology Laboratory, Centro de Investigaciones Biológicas del Noroeste, Calle IPN 195, Playa Palo de Santa Rita Sur, 23096, La Paz, BCS, Mexico.
This study identified and determined organochloride pesticide (OCs) concentrations in hair samples from children at two elementary schools: one exposed to fumigations in agricultural fields, the other unexposed. Three concentrations of OCs levels in the hair were compared (high, medium, low), and total nuclear abnormalities in buccal cells were determined: micronuclei (MNi), condensed chromatin, karyorrhexis, pyknosis, binucleate cells, karyolysis, lobed nuclei, and apoptosis. No significant differences were found for the presence of MNi between the schoolchildren from the exposed and unexposed schools, but the prevalence of OCs in both schools was over 50%, as well as the frequencies of MNi in the children were over 58%. Read More