2,743 results match your criteria electrocardiographic echocardiographic


QRS dispersion detected in ARVC patients and healthy gene carriers using 252-leads Body Surface Mapping - an explorative study of a potential diagnostic tool for Arrhythmogenic Right Ventricular Cardiomyopathy.

Pacing Clin Electrophysiol 2021 Jun 10. Epub 2021 Jun 10.

Department of Cardiology and Medical Science, Uppsala University, Uppsala, SE-75185, Sweden.

Background: The diagnosis of ARVC remains complex requiring both imaging and electrocardiographic (ECG) techniques. The purpose was therefore to investigate whether QRS dispersion assessed by body surface mapping (BSM) could be used to detect early signs of ARVC, particularly in gene carriers.

Methods: ARVC patients, gene carriers without a history of arrhythmias or structural cardiac changes and healthy controls underwent 12 lead resting ECG, signal-averaged ECG, echocardiographic examination, 24-hours Holter monitoring and BSM with electrocardiographic imaging. Read More

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Relationship between electrocardiographic interatrial blocks and echocardiographic indices of left atrial function in acute heart failure.

Heart Vessels 2021 Jun 6. Epub 2021 Jun 6.

Cardiovascular Department, Sassari University Hospital, Via Enrico De Nicola, 07100, Sassari, Italy.

The presence of an interatrial block (IAB) on surface ECG should be considered as a hallmark of atrial electrical remodelling. This is often accompanied by morphological abnormalities. We aimed to investigate the frequency of IAB and its relationship with the echocardiographic indices of left atrial (LA) remodelling in patients hospitalised with acute HF. Read More

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Circulating Levels of MicroRNAs in Hypertrophic Cardiomyopathy: The Relationship With Left Ventricular Hypertrophy, Left Atrial Dilatation and Ventricular Depolarisation-Repolarisation Parameters.

Heart Lung Circ 2021 Jun 1. Epub 2021 Jun 1.

Department of Genetics, Aziz Sancar Institute of Experimental Medicine and Department of Medical Genetics, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Background: MicroRNAs are small, endogenous, non-coding RNAs that regulate the expression of many genes. It has recently been shown that circulating microRNAs may be biomarkers of hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy (HCM).

Objective: To determine whether circulating levels of microRNAs involved in HCM are associated with electrocardiographic and echocardiographic parameters. Read More

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Association Between Left Atrial Volume Index and Ventricular Repolarization Heterogeneity: A Cross-Sectional Study of a Healthy Chinese Population.

Int J Gen Med 2021 27;14:2117-2125. Epub 2021 May 27.

Department of Cardiology, The Fourth Affiliated Hospital of China Medical University, Shenyang, People's Republic of China.

Background: Electromechanical coupling may play a significant role in the association between abnormal myocardial mechanics and heterogeneity of repolarization. This study sought to assess the potential relationship between the left atrial volume index (LAVI), which is an important marker of cardiac diastolic function, and ventricular repolarization variables, such as the QT interval, Tpeak-to-Tend (Tpe) interval and Tpe/QT ratio, in an apparently healthy Chinese population.

Methods: This was a community-based cross-sectional study conducted in Shenyang, China. Read More

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Biventricular versus His bundle pacing after atrioventricular node ablation in heart failure patients with narrow QRS.

Acta Cardiol 2021 Jun 2:1-9. Epub 2021 Jun 2.

Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

His bundle pacing (HBP) is a physiological alternative to biventricular (BiV) pacing. We compared short-term results of both pacing approaches in symptomatic atrial fibrillation (AF) patients with moderately reduced left ventricular (LV) ejection fraction (EF ≥35% and <50%) and narrow QRS (≤120 ms) who underwent atrioventricular node ablation (AVNA). Thirty consecutive AF patients who received BiV pacing or HBP in conjunction with AVNA between May 2015 and January 2020 were retrospectively assessed. Read More

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Cardiac Manifestations in a Group of Romanian Patients with Gaucher Disease Type 1 (a Monocentric Study).

Diagnostics (Basel) 2021 May 29;11(6). Epub 2021 May 29.

Faculty of Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Gaucher disease (GD), one of the most common lysosomal disorders, is characterised by clinical heterogeneity. Cardiac involvement is rare and refers to pulmonary hypertension (PH), valvular abnormalities and myocardial infiltrative damage. The aim of this study was to evaluate cardiac involvement in a group of Romanian GD patients. Read More

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Electrocardiographic Versus Echocardiographic Left Ventricular Hypertrophy in Severe Aortic Stenosis.

J Clin Med 2021 May 27;10(11). Epub 2021 May 27.

Second Department of Cardiology, Institute of Cardiology, Jagiellonian University Medical College, Jakubowskiego Street, 30-688 Cracow, Poland.

Although ECG used to be a traditional method to detect left ventricular hypertrophy (LVH), its importance has decreased over the years and echocardiography has emerged as a routine technique to diagnose LVH. Intriguingly, an independent negative prognostic effect of the "electrical" LVH (i.e. Read More

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Major Left Bundle Branch Block and Coronary Heart Disease-Are There Any Differences between the Sexes?

J Clin Med 2021 May 25;10(11). Epub 2021 May 25.

"Iuliu Hațieganu", University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Left bundle branch block is not a benign pathology, and its presence requires the identification of a pathological substrate, such as ischemic heart disease. Left bundle branch block appears to be more commonly associated with normal coronary arteries, especially in women. The objectives of our study were to describe the particularities of left bundle branch block in women compared to men with ischemic heart disease. Read More

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Anorexia nervosa-related cardiopathy in children with physical instability: prevalence, echocardiographic characteristics and reversibility at mid-term follow-up.

Eur J Pediatr 2021 May 28. Epub 2021 May 28.

Child and Adolescent Neuropsychiatric Unit, Divison of Pediatrics, Dpt of Translational Medical Sciences, Federico II University, Naples, Italy.

Prompt detection of cardiovascular abnormalities in children with anorexia nervosa and physical instability requiring hospitalization is essential to identify patients at higher cardiovascular risk. We studied all anorexia nervosa children requiring admission at Paediatric Institute in the period 2015-2019. Anorexia nervosa cardiopathy at admission was defined by the presence of at least two of the following clinical findings: pericardial effusion, mitral regurgitation, bradycardia, mitral billowing, aortic regurgitation, altered LV morphology and ECG abnormalities. Read More

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Echocardiographic and electrocardiographic assessments in patients with psoriasis.

Caspian J Intern Med 2021 Mar;12(2):162-166

Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.

Background: Psoriasis is a chronic inflammatory disease affecting many organs. Recent studies have demonstrated that psoriasis is associated with cardiovascular disorders. We investigated the echocardiographic and conduction system changes in psoriasis patients. Read More

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The clinical utility of direct His-bundle pacing in patients with heart failure and permanent atrial fibrillation.

Acta Cardiol 2021 May 19:1-8. Epub 2021 May 19.

Department of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, Wroclaw, Poland.

In patients with significantly impaired left ventricle function permanent atrial fibrillation (AF) often coexists with symptoms of heart failure. Based on various studies, it is assumed that in patients with heart failure in functional class III and IV AF occurs in 40-50% of patients. AF adversely affects cardiac hemodynamics, and its harmfulness increases particularly in the failing heart. Read More

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Differences in clinical and echocardiographic variables and mortality predictors among older patients with pulmonary embolism.

Aging Clin Exp Res 2021 May 17. Epub 2021 May 17.

Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Tibbiye street No: 13, Uskudar/Istanbul, Istanbul, 34668, Turkey.

Background: An increase in short-term mortality can be found among older patients with hemodynamically stable acute pulmonary embolism (APE) who have signs of right ventricular (RV) dysfunction.

Aims: This study was designed to assess whether any difference exists among clinical, laboratory, electrocardiography and echocardiography parameters between older and younger patients diagnosed with APE.

Methods: The study sample included a total of 635 patients with confirmed APE who were divided into two groups of older (65 years and older) and younger (younger than 65 years) individuals. Read More

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Boosting Akt Pathway by Rupatadine Modulates Th17/Tregs Balance for Attenuation of Isoproterenol-Induced Heart Failure in Rats.

Front Pharmacol 2021 30;12:651150. Epub 2021 Apr 30.

Department of Pharmacology & Toxicology, Cairo University, Cairo, Egypt.

Disruption of Th17/Tregs homeostasis plays a crucial role in governing the immune response during myocardial fibrosis and its progression to heart failure. The present study aimed to assess for the first time the possible protection afforded by rupatadine against isoproterenol-induced heart failure in rats. It also explored the role of PI3k/Akt as a possible mechanistic pathway, through which rupatadine could modulate Th17/Tregs balance to display its effect. Read More

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Cardiac abnormalities in girls with Turner syndrome: ECG abnormalities, myocardial strain imaging, and karyotype-phenotype associations.

Am J Med Genet A 2021 May 10. Epub 2021 May 10.

Department of Pediatric Cardiology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.

Turner syndrome (TS) is a chromosomal condition which is associated with an increased prevalence of cardiac morbidity and mortality. In this cross-sectional study, Minnesota-based electrocardiographic (ECG) abnormalities, aortic dimensions, routine- and myocardial strain echocardiographic parameters, and karyotype-cardiac phenotype associations were assessed in girls with TS. In total, 101 girls with TS (0-18 years) were included. Read More

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Clinical features and outcome of MIS-C patients: an experience from Central Anatolia.

Clin Rheumatol 2021 May 6. Epub 2021 May 6.

Department of Pediatric Critical Care, Selcuk University Faculty of Medicine, Konya, Turkey.

Background: Multisystem inflammatory syndrome in children (MIS-C) is a new clinical condition characterized by signs of inflammation and multiorgan dysfunction due to cytokine storm associated with SARS-CoV-2. The clinical spectrum of MIS-C ranges from mild to severe, and even to mortal multisystem involvement. To guide clinicians, we evaluated detailed demographic characteristics, clinical features, laboratory findings, and outcomes of MIS-C cases. Read More

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Could Serum Copeptin Level Be an Indicator of Coronary Artery Disease Severity in Patients with Unstable Angina?

Int Heart J 2021 May 1;62(3):528-533. Epub 2021 May 1.

Department of Cardiology, Gebze Fatih State Hospital.

This study aimed to identify the serum copeptin levels in patients diagnosed with unstable angina (UA) and evaluate the relationship between the patients' copeptin levels and angiographic severity.A total of 200 patients who were diagnosed with UA and underwent coronary angiography were included in the study. Clinical, electrocardiographic, echocardiographic, and laboratory data (high-sensitivity cardiac troponin T and copeptin levels) as well as The Global Registry of Acute Coronary Events (GRACE) 1. Read More

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TSH variations in chronic heart failure outpatients: clinical correlates and outcomes.

Endocr Metab Immune Disord Drug Targets 2021 Apr 30. Epub 2021 Apr 30.

Cardiology Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia. Italy.

Background: Hypothyroidism is a frequently observed comorbidity in patients with chronic heart failure (CHF), possibly giving rise to unfavorable outcomes.

Aim: The aim of the study was to evaluate the impact of TSH changes over time on cardiac function and prognosis of outpatients with CHF.

Methods: Patients underwent clinical, electrocardiographic, and echocardiographic evaluations at baseline and after 12 months. Read More

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Myocardial strain analysis using cardiac magnetic resonance in patients with calpainopathy.

Orphanet J Rare Dis 2021 Apr 30;16(1):194. Epub 2021 Apr 30.

Department of Internal Medicine and Cardiology, Herzzentrum Dresden Universitätsklinik, Technische Universität Dresden, Dresden, Germany.

Background: Limb-girdle muscular dystrophy (LGMD) is a genetically and clinically heterogeneous group of rare muscular dystrophies. Subtype 2A (LGMD2A) also known as "calpainopathy" is an inherited autosomal recessive gene defect. Cardiac dysfunction is common in several forms of LGMD. Read More

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Deriving a parsimonious cardiac endpoint for use in epidemiological studies of Chagas disease: results from the Retrovirus Epidemiology Donor Study-II (REDS-II) cohort.

Rev Inst Med Trop Sao Paulo 2021 23;63:e31. Epub 2021 Apr 23.

Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo, São Paulo, São Paulo, Brazil.

Chagas cardiomyopathy (ChCM) is a severe consequence of Trypanosoma cruzi infection and has a range of electrocardiographic (ECG) and echocardiographic (ECHO) manifestations. There is a need for a standard and parsimonious research cardiac end point that does not rely on expert panel adjudication, and it is not intended to change the ChCM definition. We use data from the REDS-II cohort to propose a simplified cardiac endpoint. Read More

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A pilot study investigating the effect of pimobendan on the cardiac rhythm and selected echocardiographic parameters of healthy cats.

J Vet Cardiol 2021 Mar 24;35:74-83. Epub 2021 Mar 24.

Laboratory of Physiology II, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara-shi, Kanagawa, Japan.

Introduction: The effects of pimobendan on the heart rhythm in cats are unknown. The purpose of this pilot study was to evaluate the effect of pimobendan on the cardiac rhythm and selected echocardiographic parameters of cats.

Animals, Materials, And Methods: Six clinically healthy cats received each of four medication protocols for 15 days, with a washout period of at least one month between each protocol. Read More

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Machine learning versus classic electrocardiographic criteria for the detection of echocardiographic left ventricular hypertrophy in a pre-participation cohort.

Kardiol Pol 2021 Apr 16. Epub 2021 Apr 16.

Background: Classical electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH) are well studied in older populations and patients with hypertension. Their utility in young pre-participation cohorts is unclear.

Aims: We aimed to develop machine learning models for detection of echocardiogram-diagnosed LVH from ECG, and compare these modelswith classical criteria. Read More

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The usefulness of morphology-voltage-P wave duration ECG score for predicting early left atrial dysfunction in hypertensive patients.

Clin Exp Hypertens 2021 Apr 19:1-7. Epub 2021 Apr 19.

Department of Cardiology, Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey.

: Left atrial (LA) function is an important predictor of adverse cardiovascular outcomes in patients with hypertension (HT). Therefore, recognition of subtle LA dysfunction in the early stages of HT is essential for controlling modifiable variables. Several electrocardiographic and echocardiographic parameters have been studied to show early LA dysfunction. Read More

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Effect of dialysis and transplantation on myocardial repolarization parameters and P-wave dispersion in chronic kidney disease.

J Arrhythm 2021 Apr 8;37(2):348-355. Epub 2021 Feb 8.

Department of Cardiology Faculty of Medicine Ondokuz Mayis University Samsun Turkey.

Background: Chronic kidney disease (CKD) patients are at higher risk for cardiac arrhythmias. The risk of arrhythmia may change with different treatment modalities. We proposed to compare the effects of varied therapy methods on myocardial repolarization parameters (Tp-e, QT, QTc intervals, Tp-e/QT, Tp-e/QTc ratios) and P-wave dispersion (PWD) in patients with CKD. Read More

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Effect of chelation therapy on arrhythmogenic and basal ECG parameters of lead exposed workers.

Arch Environ Occup Health 2021 Apr 10:1-7. Epub 2021 Apr 10.

Department of Cardiology, Ankara City Hospital, Ankara, Turkey.

Lead exposure has etiological role on cardiovascular system diseases as hypertension, atherosclerosis, stroke, and arrhythmic events. In this study, we aimed to compare the basal and arrhythmogenic ECG parameters of lead exposed workers before and after chelation therapy and to evaluate the effect of acute change of blood lead levels on ECG. Fourty consecutive occupationally lead exposed workers were enrolled, demographic, blood, echocardiographic, and electrocardiographic data's were analyzed before and after chelation therapy. Read More

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Severe Preeclampsia is Associated with Functional and Structural Cardiac Alterations: A Case-control Study.

Z Geburtshilfe Neonatol 2021 Apr 9. Epub 2021 Apr 9.

Department of Cardiology, Pamukkale University, Denizli, Turkey.

Background: The aim of the current study is to compare electrocardiographic and echocardiographic changes in patients with severe preeclampsia (PE) and those with uncomplicated pregnancies.

Methods: This is a case-controlled prospective study consisting of 21 pregnant women with severe preeclampsia and a control group consisting of age- and gestational age-matched 24 healthy pregnant women. All patients underwent electrocardiographic and echocardiographic investigation. Read More

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Left Ventricular Longitudinal Global Strain to Predict Severe Coronary Disease in Patients with Precordial Pain Suggestive of Non-ST-Segment Elevation Acute Coronary Syndrome.

J Cardiovasc Echogr 2020 Oct-Dec;30(4):187-192. Epub 2021 Jan 20.

Department of Cardiology, Sanatorium Allende, Córdoba, Argentina.

Background: Diagnosing non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is not always straightforward. Left ventricular global longitudinal strain (LVGLS) is an echocardiographic method capable of detecting subclinical regional and global ventricular contractile dysfunction due to myocardial ischemia. The objectives of this study were to evaluate the efficacy of LVGLS in diagnosing severe coronary disease in patients with chest pain suggestive of NSTE-ACS and to assess the relationships between LVGLS reduction and ultrasensitive troponin T (UsTnT) elevation, electrocardiographic changes suggestive of ischemia, and the number of vessels with severe obstructions. Read More

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January 2021

Left Bundle Branch Block-induced Cardiomyopathy: Insights From Left Bundle Branch Pacing.

JACC Clin Electrophysiol 2021 Mar 25. Epub 2021 Mar 25.

Geisinger Heart Institute, Geisinger Commonwealth School of Medicine, Wilkes-Barre, Pennsylvania, USA. Electronic address:

Objectives: The aim of the study was to report the efficacy of left bundle branch pacing (LBBP) in the management of left bundle branch block (LBBB)-induced cardiomyopathy (LIC).

Background: Chronic LBBB is known to cause mechanical dyssynchrony and cardiomyopathy. Hyperresponse to cardiac resynchronization therapy (CRT) with biventricular pacing (BVP) is a hallmark of LIC. Read More

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T-wave peak-end interval and ratio of T-wave peak-end and QT intervals: novel arrhythmogenic and survival markers for dogs with myxomatous mitral valve disease.

J Vet Cardiol 2021 Feb 27;35:25-41. Epub 2021 Feb 27.

Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, PR, 80035-050, Brazil.

Introduction/objectives: In the past few years, novel markers such as the interval between the peak and the end of T-wave (Tpte) and Tpte/QT ratio have been shown to have high sensitivity for ventricular arrhythmias and mortality. We analyzed these and other parameters of ventricular repolarization, such as QT interval, QT interval corrected for heart rate (QTc), and QT dispersion (QTd) in dogs with myxomatous mitral valve disease (MMVD). Additionally, we investigated their relationship with the progression of the disease, echocardiographic parameters, and ventricular arrhythmias and assessed their prognostic value with development of clinical signs or mortality as the final outcome. Read More

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February 2021

Unusual Presentation of Aortic Valve Infective Endocarditis in a Dog: Aorto-Cavitary Fistula, Tricuspid Valve Endocarditis, and Third-Degree Atrioventricular Block.

Animals (Basel) 2021 Mar 4;11(3). Epub 2021 Mar 4.

Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy.

A 2-year-old Boxer with a history of subaortic stenosis and immunosuppressant therapy developed aortic valve infective endocarditis. On echocardiographic examination with simultaneous electrocardiographic tracing, multiple uncommon periannular complications of the aortic valve endocarditis were found, including aorto-cavitary fistula with diastolic left-to-right shunt, tricuspid valve endocarditis, and third-degree atrioventricular block. Necropsy confirmed the above echocardiographic findings. Read More

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Deletion of Kvβ2 (AKR6) Attenuates Isoproterenol Induced Cardiac Injury with Links to Solute Carrier Transporter SLC41a3 and Circadian Clock Genes.

Metabolites 2021 Mar 29;11(4). Epub 2021 Mar 29.

Department of Pharmaceutical Sciences, Taneja College of Pharmacy, University of South Florida, Tampa, FL 33612, USA.

Kvβ subunits belong to the aldo-keto reductase superfamily, which plays a significant role in ion channel regulation and modulates the physiological responses. However, the role of Kvβ2 in cardiac pathophysiology was not studied, and therefore, in the present study, we hypothesized that Kvβ2 plays a significant role in cardiovascular pathophysiology by modulating the cardiac excitability and gene responses. We utilized an isoproterenol-infused mouse model to investigate the role of Kvβ2 and the cardiac function, biochemical changes, and molecular responses. Read More

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