1,713 results match your criteria egg allergic


[Effect of intranasal acupuncture on neurogenic inflammation in allergic rhinitis rabbits].

Zhen Ci Yan Jiu 2021 Feb;46(2):111-6

Beijing University of Chinese Medicine, Beijing 100029.

Objective: To observe the effect of intranasal acupuncture on allergic rhinitis (AR), and expression of substance P (SP), vasoactive intestinal peptide (VIP) and neuropeptide Y (NPY) proteins in the nasal mucosa and contents of serum immunoglobulin E (IgE), interleukin 4 (IL-4) and interferon-γ (IFN-γ) in AR rabbits, so as to explore its mechanisms underlying improvement of AR.

Methods: New Zealand rabbits were randomly divided into normal control, AR model, non-acupuoint acupuncture (NAA) and intranasal acupuncture (INA) groups, with 8 rabbits in each group. The AR model was established by intra-peritoneal injection of egg protein and nasal mucosal stimulation. Read More

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February 2021

Post-transplant food anaphylaxis in an adult cord blood transplant recipient (Ms. No. IJHM-D-20-01037R1).

Int J Hematol 2021 Mar 27. Epub 2021 Mar 27.

University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi, Kitakyushu, 807-8556, Japan.

Transplant acquired food allergy (TAFA) is a well-known complication following pediatric liver transplantation, but post-cord blood transplantation (post-CBT) TAFA has rarely been reported. Here, we describe a case of new-onset food anaphylaxis after CBT in an adult patient that demonstrates that post-CBT allergen-challenge is not a risk for long-term allergic sensitization even in adult recipients. The patient was a 39-year-old Japanese man with aggressive NK cell leukemia. Read More

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Extract and molecular-based early infant sensitisation and associated factors - a PreventADALL study.

Allergy 2021 Mar 9. Epub 2021 Mar 9.

Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.

Background: More knowledge about sensitisation patterns in early infancy, including impact of molecular allergology, is needed to help predict future allergy development more accurately.

Objective: We aimed to determine the prevalence and patterns of allergic sensitisation at three months of age, and explore possible associated factors.

Methods: From the Scandinavian antenatally recruited PreventADALL mother-child cohort we included 1110 three-months-infants with available serum. Read More

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[ALLERGY PREVENTION AND TREATMENT DURING THE FIRST YEAR].

Harefuah 2021 Mar;160(3):161-166

Maccabi Health Care.

Introduction: The effect of the pregnant mother's nutrition and the effect of the baby's nutrition during the first-year on the development of allergy and atopic disease in the baby have been studied extensively in recent years. Key recommendations for healthcare bodies in Europe and the United States include: • Allergy prevention in at-risk infants (parent or sibling with allergy): Currently, there is a consensus of healthcare organizations around the world that the recommended exclusive breastfeeding duration is the first 6 months of life for the overall health benefit of the baby. Allergy prevention in non-breastfed infants at risk: There are studies showing that fully hydrolyzed formula can reduce the risk of allergic reactions, especially atopic dermatitis, in high-risk non-breastfed babies. Read More

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Sensitization to peanut, egg or pets is associated with skin barrier dysfunction in children with atopic dermatitis.

Clin Exp Allergy 2021 Mar 15. Epub 2021 Mar 15.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Background: Children with atopic dermatitis (AD) are often sensitized to food and aeroallergens, but sensitization patterns have not been analysed with biologic measures of disease pathogenicity.

Objective: We sought to define allergen sensitization grouping(s) using unbiased machine learning and determine their associations with skin filaggrin (FLG) and transepidermal water loss (TEWL) (assesses skin barrier integrity), S100A8 and S100A9 expression (assesses skin inflammation) and AD severity.

Methods: We studied 400 children with AD in the Mechanisms of Progression from Atopic Dermatitis to Asthma in Children (MPAACH) cohort to identify groupings of food and aeroallergen sensitizations. Read More

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Mucosal Nanoemulsion Allergy Vaccine Suppresses Alarmin Expression and Induces Bystander Suppression of Reactivity to Multiple Food Allergens.

Front Immunol 2021 25;12:599296. Epub 2021 Feb 25.

Mary H. Weiser Food Allergy Center, University of Michigan, Ann Arbor, MI, United States.

We have demonstrated that intranasal immunotherapy with allergens formulated in a nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and protects from allergen challenge in murine food allergy models. Protection conferred by this therapy is associated with strong suppression of allergen specific Th2 cellular immunity and increased Th1 cytokines. Here we extend these studies to examine the effect of NE-allergen immunization in mice sensitized to multiple foods. Read More

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February 2021

Sex-specific associations of human milk long-chain polyunsaturated fatty acids and infant allergic conditions.

Pediatr Allergy Immunol 2021 Mar 12. Epub 2021 Mar 12.

Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.

Background: Polyunsaturated fatty acids (PUFAs) may influence immune development. We examined the association of PUFAs in human milk with food sensitization and atopic dermatitis among breastfed infants.

Methods: In a selected subgroup of 1109 mother-infant dyads from the CHILD Cohort Study, human milk was analyzed by gas-liquid chromatography to quantify PUFAs including arachidonic acid (ARA) and docosahexaenoic acid (DHA). Read More

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EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update).

Pediatr Allergy Immunol 2021 Mar 12. Epub 2021 Mar 12.

Clinical and Experimental Sciences and Human Development in Health, Faculty of Medicine, University of Southampton, Southampton, UK.

Background: This guideline from the European Academy of Allergy and Clinical Immunology (EAACI) recommends approaches to prevent the development of immediate-onset / IgE-mediated food allergy in infants and young children. It is an update of a 2014 EAACI guideline.

Methods: The guideline was developed using the AGREE II framework and the GRADE approach. Read More

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Quantification of crustacean tropomyosin in foods using high-performance liquid chromatography-tandem mass spectrometry method.

J Sci Food Agric 2021 Mar 1. Epub 2021 Mar 1.

College of Food Science and Engineering, Ocean University of China, Qingdao, People's Republic of China.

Background: Allergic reactions to crustacean products have been increasing owing to the rising consumption. Tropomyosin (TM) is the main crustacean allergen; it has a coiled-coil structure, which shows stability to various food processing methods. Crustacean processed products have been used in several food products, thereby causing greater difficulties in detecting TM in these products. Read More

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Component resolved diagnosis of egg yolk is an indispensable part of egg allergy.

Allergol Immunopathol (Madr) 2021 1;49(2):6-14. Epub 2021 Mar 1.

School of Medical Laboratory, Tianjin Medical University, Tianjin, China;

Introduction And Objectives: It was urgent to explain the role of egg yolk allergen sensitization to the egg allergic population and we would evaluate the diagnostic value of allergen components in whole eggs, including egg white and egg yolk.

Materials And Methods: Firstly, we collected 99 positive and 21 negative sera against egg allergy. Then we used modified enzyme linked immunosorbent assay (ELISA) to survey specific IgE (sIgE) to all-proven and single component in eggs, Ovomucoid (Gal d 1), Ovalbumin (Gal d 2), Ovotransferrin (Gal d 3), Lysozyme C (Gal d 4), Serum Albumin (Gal d 5), and YGP42(Gal d 6) in allergic and non-allergic populations. Read More

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A Food, a Bite, a Sip: How Much Allergen Is in That?

Nutrients 2021 Feb 10;13(2). Epub 2021 Feb 10.

Department of Nutrition and Dietetics, Hanze University of Applied Sciences, 9713 GZ Groningen, The Netherlands.

Detailed information about the amount of allergenic protein ingested by the patient prior to an allergic reaction yields valuable information for the diagnosis, guidance and management of food allergy. However, the exact amount of ingredients is often not declared on the label. In this study the feasibility was studied for estimating the amount of allergenic protein from milk, eggs, peanuts and hazelnuts in frequently consumed composite and non-composite foods and per bite or sip size in different age groups in the Netherlands. Read More

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February 2021

Food allergy treatment value: Child caregiver and patient perspectives.

Pediatr Allergy Immunol 2021 Feb 5. Epub 2021 Feb 5.

Department of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore, MD, USA.

Background: Food allergy is a major health problem that significantly impacts quality of life (QoL). There is growing focus to evaluate food allergy-related QoL and treatment options' value beyond the clinical effectiveness perspective by engaging patients and caregivers. We aimed to identify and prioritize outcomes important to food allergy parents of children and patients allergic to milk, egg, and/or peanut, to guide comparative effectiveness research (CER) that focuses on evaluating food allergy treatment decisions. Read More

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February 2021

Food allergy history and reaction to propofol administration in a large pediatric population.

Paediatr Anaesth 2021 May 18;31(5):570-577. Epub 2021 Feb 18.

Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Background: Anaphylaxis to propofol is rare; however, providers face a clinical quandary as medication warnings still exist regarding propofol administration to egg-, soy-, and peanut-allergic patients.

Aims: The primary aim evaluated the rate of allergic reactions during propofol-containing anesthesia in patients listed allergic to egg, soy, or peanut compared with nonallergic patients who received propofol. The secondary aim evaluated the relationship between food allergy history and allergy testing data. Read More

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Specific IgE levels as an outcome predictor in egg-allergic children.

Allergol Immunopathol (Madr) 2021 2;49(1):79-86. Epub 2021 Jan 2.

Pediatrics Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.

Background: Diagnosis of immunoglobulin E (IgE)-mediated egg allergy is often based on both a compatible clinical history and either elevated IgE levels or a positive skin prick test. However, the gold standard is the oral food challenge (OFC). Previous studies have pointed to a correlation between IgE levels and OFC outcomes. Read More

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January 2021

Prevalence of allergic disorders and risk factors associated with food allergy in Turkish preschoolers.

Allergol Immunopathol (Madr) 2021 2;49(1):11-16. Epub 2021 Jan 2.

School of Medicine, Division of Pediatric Allergy and Immunology, Marmara University, Istanbul, Turkey.

Background: The prevalence of allergic disorders is on the rise, affecting about 10% of the population. In this retrospective cohort, we investigated prevalence of allergic disorders, associated risk factors, and the outcome of food allergies.

Material And Methods: We analyzed data from birth cohorts of two university hospitals' well-child outpatient clinics. Read More

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January 2021

Long-Chain Polyunsaturated Fatty Acids (LCPUFAs) and the Developing Immune System: A Narrative Review.

Nutrients 2021 Jan 16;13(1). Epub 2021 Jan 16.

Faculty of Medicine, School of Human Development and Health, University of Southampton, Southampton SO16 6YD, UK.

The immune system is complex: it involves many cell types and numerous chemical mediators. An immature immune response increases susceptibility to infection, whilst imbalances amongst immune components leading to loss of tolerance can result in immune-mediated diseases including food allergies. Babies are born with an immature immune response. Read More

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January 2021

Are infants with food allergy candidates for respiratory allergy?

Turk Pediatri Ars 2020 16;55(4):354-360. Epub 2020 Dec 16.

Department of Pediatrics, Balıkesir University Faculty of Medicine, Balıkesir, Turkey.

Aim: Allergic sensitization in infancy generally develops against food allergens. We aimed to investigate the frequency of aero-allergens sensitization at older ages in infants with food allergy.

Material And Methods: This retrospective cross-sectional study was conducted in Dr. Read More

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December 2020

Influence of Antihistamines on Basophil Activation Test in Food Allergy to Milk and Egg.

Diagnostics (Basel) 2020 Dec 30;11(1). Epub 2020 Dec 30.

UOSD Allergologia e Immunologia Clinica, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.

Background: The basophil activation test (BAT) is used to improve the accuracy of food allergy diagnosis. To date, the influence of antiallergic drugs on BAT reactivity is poorly investigated. The aim of the study was to investigate if BAT results were influenced by antihistamine intake for 3 months in a cohort of patients with IgE-mediated food allergy to milk or egg. Read More

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December 2020

Prevention of food allergy: can we stop the rise of IgE mediated food allergies?

Curr Opin Allergy Clin Immunol 2021 Apr;21(2):195-201

Department of Women and Children's Health (Paediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London.

Purpose Of Review: Food allergy has become more prevalent in recent decades. Without a curative treatment for food allergy, prevention is key. Can we intervene and halt the food allergy epidemic?

Recent Findings: There are three main hypotheses to explain the rise in food allergy: the dual-allergen exposure hypothesis, the hygiene hypothesis and the vitamin D hypothesis. Read More

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IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice.

Front Immunol 2020 11;11:596772. Epub 2020 Dec 11.

Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany.

Food allergies are common, costly and potentially life-threatening disorders. They are driven by Th2, but inhibited by Th1 reactions. There is also evidence indicating that IL-2 agonist treatment inhibits allergic sensitization through expansion of regulatory T cells. Read More

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December 2020

Multi-target detection of egg-white and pig gelatin fining agents in Nebbiolo-based aged red wine by means of nanoHPLC-HRMS.

Food Chem 2021 May 7;345:128822. Epub 2020 Dec 7.

Institute of Sciences of Food Production, National Research Council, Largo Braccini 2, 10095 Grugliasco (TO), Italy. Electronic address:

The presence of residues from fining agents in wines may represent a risk for allergic consumers and a source of discomfort for others, such as vegans. Even though ELISA is the official detection method for such residues, this technique may be hindered by cross-reactivity issues, or by matrix-molecule interference due to a high polyphenol content, especially in red wines. An HRMS-based method has been developed to detect pig gelatin and egg white in experimental five-year aged Nebbiolo-based red wine. Read More

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Evaluation of baked egg oral immunotherapy in French children with hen's egg allergy.

Pediatr Allergy Immunol 2020 Dec 22. Epub 2020 Dec 22.

Department of Respiratory Medicine and Allergic Diseases, University Hospital Centre of Toulouse, Toulouse, France.

Background: Introduction and gradual incremental escalation of a low dose of baked egg may accelerate the resolution of severe hen's egg (HE) allergy for some children. The purpose of our study was to evaluate the efficacy and safety of baked egg oral immunotherapy (OIT) in children with HE allergy after a low-dose baked egg oral food challenge (OFC).

Methods: In a retrospective analysis of OFC performed between 2013 and 2018 at the Children's Hospital of Toulouse (France), we identified 71 children with HE allergy and high egg-white (EW) and ovomucoid specific IgE levels, who underwent a total of 164 OFC (71 baked egg, then 93 unbaked egg). Read More

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December 2020

Timing of onset of allergic symptoms following low-dose milk and egg challenges.

Pediatr Allergy Immunol 2021 Apr 13;32(3):612-615. Epub 2021 Jan 13.

Department of Allergy, Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Kanagawa, Japan.

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Analysis of the immunoglobin E molecular sensitization profile in children with allergic asthma and predictive factors for the efficacy of allergy immunotherapy.

Ann Transl Med 2020 Nov;8(21):1459

Department of Respiratory Medicine Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.

Background: As the incidence of allergic asthma in children increases, the immunoglobin E (IgE) molecular sensitization profile of allergic asthma remains underreported while the level of total IgE (tIgE) and sIgE/tIgE have not been studied as predictors of efficacy of allergen immunotherapy (AIT) for allergic asthma, specifically in children.

Methods: Starting from August 2018 to March 2019 in the Respiratory Department of the Children's Hospital of Chongqing Medical University, asthmatic children, with positive skin prick tests to Der p or Der f, were enrolled in this study. Total IgE, allergen serum-specific IgE (sIgE) of Der p, Der f, (Blo t), cat dander, dog dander, egg white, milk, cockroach, shrimp, and crab, along with Der p allergen components, Der p1 and Der p2, were measured by ImmunoCAP™ assay. Read More

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November 2020

WAYS OF OPTIMIZING THE DIAGNOSTICS OF FOOD ALLERGIES IN CHILDREN BASED ON THE CLINICAL AND IMMUNOLOGICAL CRITERIA.

Wiad Lek 2020 ;73(10):2255-2260

UKRAINIAN MEDICAL STOMATOLOGICAL ACADEMY, POLTAVA, UKRAINE.

Objective: The aim of the research was to investigate the spectrum of food sensitization, followed by the determination of the main clinical criteria and immunological markers of food allergy in children with gastroduodenal pathology and atopic dermatitis.

Patients And Methods: Materials and methods: We conducted a comprehensive clinical and immunological examination of 120 children aged from 6 to 15 years with gastroduodenal pathology (group 1; n = 64) and atopic dermatitis (group 2; n = 56), who had a history of adverse allergic reactions to food. The control group consisted of 22 apparently healthy children. Read More

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December 2020

Investigation of Allergic Sensitization Pattern in 4,203 Children in Northern China.

Int Arch Allergy Immunol 2020 Dec 9:1-4. Epub 2020 Dec 9.

First Affiliated Hospital , Shanxi Medical University, Taiyuan, China,

Objective: The objective of this study is to investigate the allergen sensitization pattern among 4,203 children in the Shanxi region of China and to provide guidance for diagnosis and prevention of allergic diseases.

Methods: A retrospective analysis was conducted on the allergen-specific immunoglobulin E (sIgE) results of 4,203 children aged 0-12 years from January to December in 2019. SIgE antibodies to 19 allergens in the serum sample were detected by enzyme ALLERGO-SORBENT testing. Read More

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December 2020

Safety of measles, mumps, and rubella vaccine in egg allergy: in vivo and in vitro management.

Clin Mol Allergy 2020 Nov 15;18(1):21. Epub 2020 Nov 15.

Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari-Aldo Moro, Piazza Giulio Cesare, Policlinico, 70124, Bari, Italy.

Background: Egg allergy is the second most prevalent form of food allergy in childhood. In spite of the evidence accumulated, inoculating egg allergy children with attenuated vaccines grown on chick embryo cell cultures, such as the measles, mumps, and rubella (MMR) vaccine, is regarded (erroneously) as potentially dangerous or even anaphylactogenic, by many. An issue perceived as particularly conflicting also by Health Professionals. Read More

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November 2020

Food and food products associated with food allergy and food intolerance - An overview.

Food Res Int 2020 12 15;138(Pt B):109780. Epub 2020 Oct 15.

Instrumental and Food Analysis Laboratory, School of Biosciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu 632014, India. Electronic address:

Immune-mediated food allergy and non-immune mediated food intolerance are categorized as the most common adverse reactions resulting from the ingestion of certain foods. As there is no standard treatment, the possible remedy to avoid exposure to these adverse reactions is adhering to a strict diet that eliminates allergic and intolerant foods. The commonly consumed foods including dairy products, egg, fish, shellfish, tree nuts, peanut, soybean, and wheat-based products are proven to cause food allergy. Read More

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December 2020

Longitudinal analysis of total serum IgE levels with allergen sensitization and atopic diseases in early childhood.

Sci Rep 2020 12 4;10(1):21278. Epub 2020 Dec 4.

Division of Pediatric Pulmonology, Chang Gung Memorial Hospital at Linkou, College of Medicine, Chang Gung University, Taoyüan, Taiwan.

There are few studies addressing the longitudinal analysis of serum IgE levels and its impact to the development of atopic diseases in early childhood. We investigated 170 children who regularly followed up at our clinic for 4 years in a birth cohort study with at least 3 time-points of serum samples. The pattern of total serum IgE levels from 6 months to 4 years of age was clustered using K-means method in R software. Read More

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December 2020