290 results match your criteria efficiency ecs

Efficient and effective removal of emerging contaminants through the parallel coupling of rapid adsorption and photocatalytic degradation: A case study of fluoroquinolones.

Chemosphere 2021 May 5;280:130770. Epub 2021 May 5.

School of Chemistry, MOE Key Laboratory of Theoretical Chemistry of Environment, South China Normal University, Guangzhou, 510006, PR China. Electronic address:

The development of efficient, effective, and large-scale treatment methods to address high-risk emerging contaminants (ECs) is a growing challenge in environmental remediation. Herein, a novel parallel coupling strategy of adsorption separation and photodegradation regeneration (parallel ASPR) is proposed; subsequently, an adsorptive photocatalyst (Zn-doped BiOI) is designed to demonstrate how to effectively eliminate fluoroquinolones (FQs) from water with the proposed ASPR scheme. Compared with pure BiOI, the addition of Zn during synthesis has a significant influence on the morphology and structure of the products, resulting in Zn-doped BiOI samples with up to 5 times the specific surface area, 32 times the adsorption capacity, and 20 times the photocurrent intensity. Read More

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Potential Environmental and Human Health Risks Caused by Antibiotic-Resistant Bacteria (ARB), Antibiotic Resistance Genes (ARGs) and Emerging Contaminants (ECs) from Municipal Solid Waste (MSW) Landfill.

Antibiotics (Basel) 2021 Apr 1;10(4). Epub 2021 Apr 1.

Nutrition and Bromatology Group, Department of Analytical and Food Chemistry, Faculty of Food Science and Technology, Ourense Campus, University of Vigo, E-32004 Ourense, Spain.

The disposal of municipal solid waste (MSW) directly at landfills or open dump areas, without segregation and treatment, is a significant concern due to its hazardous contents of antibiotic-resistant bacteria (ARB), antibiotic resistance genes (ARGs), and metal resistance genes (MGEs). The released leachate from landfills greatly effects the soil physicochemical, biological, and groundwater properties associated with agricultural activity and human health. The abundance of ARB, ARGs, and MGEs have been reported worldwide, including MSW landfill sites, animal husbandry, wastewater, groundwater, soil, and aerosol. Read More

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Efficient destruction of emerging contaminants in water by UV/S(IV) process with natural reoxygenation: Effect of pH on reactive species.

Water Res 2021 Apr 15;198:117143. Epub 2021 Apr 15.

Center of Modern Analysis, Nanjing University, Nanjing, 210093, People's Republic of China.

UV/sulfite systems with oxygen have recently been considered as advanced oxidation processes in view of the participation of oxysulfur radicals. However, the contribution of •OH and the efficiency of destructing emerging contaminants (ECs) in water remain largely unclear. Here, the UV/S(IV) process was applied with natural reoxygenation to degrade two typical ECs, diethyl phthalate (DEP) and bisphenol A (BPA) showing different properties. Read More

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Direct conversion of adult human fibroblasts into functional endothelial cells using defined factors.

Biomaterials 2021 May 24;272:120781. Epub 2021 Mar 24.

Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea. Electronic address:

We aimed to directly convert adult human dermal fibroblasts (aHDFs) into functional endothelial cells (ECs). Lentiviral vectors encoding endothelial transcription factors (TFs) were constructed. We examined whether five TFs (FOXO1, ER71, KLF2, TAL1, and LMO2) used for the generation of mouse induced ECs (iECs) could convert the aHDFs into human iECs. Read More

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Endothelial Cell-Mediated Gene Delivery for In Situ Accelerated Endothelialization of a Vascular Graft.

ACS Appl Mater Interfaces 2021 Apr 31;13(14):16097-16105. Epub 2021 Mar 31.

School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Tianjin 300350, China.

As an urgently needed device for vascular diseases, the small-diameter vascular graft is limited by high thrombogenicity in clinical applications. Rapid endothelialization is a promising approach to construct an antithrombogenic inner surface of the vascular graft. The main bottleneck for rapid endothelialization is the adhesion, migration, and proliferation of endothelial cells (ECs) in situ of the small-diameter vascular graft. Read More

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A High-Efficiency Method for the Production of Endothelial Cells from Human Induced Pluripotent Stem Cells.

Methods Mol Biol 2021 Mar 24. Epub 2021 Mar 24.

Department of Dermatology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.

Endothelial cells (ECs) are important components of the circulatory system. These cells can be used for in vitro modeling of cardiovascular diseases and in regenerative medicine to promote vascularization of engineered tissue constructs. However, low proliferative capacity and patient-to-patient variability limit the use of primary ECs in the clinic and disease modeling. Read More

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Comparative Study of Human Pluripotent Stem Cell-Derived Endothelial Cells in Hydrogel-Based Culture Systems.

ACS Omega 2021 Mar 2;6(10):6942-6952. Epub 2021 Mar 2.

Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

Human pluripotent stem cell (hPSC)-derived endothelial cells (ECs) are promising cell sources for drug discovery, tissue engineering, and studying or treating vascular diseases. However, hPSC-ECs derived from different culture methods display different phenotypes. Herein, we made a detailed comparative study of hPSC-ECs from three different culture systems (e. Read More

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Monotherapy and Combination Therapy Using Anti-Angiogenic Nanoagents to Fight Cancer.

Adv Mater 2021 Apr 8;33(15):e2005155. Epub 2021 Mar 8.

Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing, 211800, China.

Anti-angiogenic therapy, targeting vascular endothelial cells (ECs) to prevent tumor growth, has been attracting increasing attention in recent years, beginning with bevacizumab (Avastin) through its Phase II/III clinical trials on solid tumors. However, these trials showed only modest clinical efficiency; moreover, anti-angiogenic therapy may induce acquired resistance to the drugs employed. Combining advanced drug delivery techniques (e. Read More

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Somatic Embryogenesis Initiation in Sugi (Japanese Cedar, D. Don): Responses from Male-Fertile, Male-Sterile, and Polycross-Pollinated-Derived Seed Explants.

Plants (Basel) 2021 Feb 19;10(2). Epub 2021 Feb 19.

Graduate School of Science and Technology, Niigata University, Ikarashi 8050, Niigata 950-2181, Japan.

This study aimed to obtain information from several embryogenic cell (EC) genotypes analyzing the factors that affect somatic embryogenesis (SE) initiation in sugi ( Cupressaceae) to apply them in the improvement of protocols for efficient induction of embryogenic cell lines (ECLs). The results of several years of experiments including studies on the influence of initial explant, seed collection time, and explant genotype as the main factors affecting SE initiation from male-fertile, male-sterile, and polycross-pollinated-derived seeds are described. Initiation frequencies depending on the plant genotype varied from 1. Read More

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February 2021

Symbiotic bracovirus of a parasite manipulates host lipid metabolism via tachykinin signaling.

PLoS Pathog 2021 Mar 1;17(3):e1009365. Epub 2021 Mar 1.

Institute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China.

Parasites alter host energy homeostasis for their own development, but the mechanisms underlying this phenomenon remain largely unknown. Here, we show that Cotesia vestalis, an endoparasitic wasp of Plutella xylostella larvae, stimulates a reduction of host lipid levels. This process requires excess secretion of P. Read More

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Mechanistic insights into paracetamol transformation in UV/NHCl process: Experimental and theoretical study.

Water Res 2021 Apr 16;194:116938. Epub 2021 Feb 16.

Key Laboratory of Building Safety and Energy Efficiency, Ministry of Education, Department of Water Engineering and Science, College of Civil Engineering, Hunan University, Changsha, 410082, China. Electronic address:

The UV/monochloramine (NHCl) process is an advanced oxidation process that can effectively remove emerging contaminants (ECs). However, the degradation mechanisms of reactive radicals with ECs are not clear. In this work, we combined theoretical calculations with experimental studies to investigate the kinetics and mechanism of radical-mediated degradation of paracetamol (AAP) in UV/NHCl process. Read More

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Current advances in microalgae-based bioremediation and other technologies for emerging contaminants treatment.

Sci Total Environ 2021 Jun 29;772:144918. Epub 2021 Jan 29.

Graduate Program in Environmental and Civil Engineering, University of Passo Fundo (UPF), Passo Fundo, Rio Grande do Sul 99052-900, Brazil. Electronic address:

Emerging contaminants (EC) have been detected in effluents and drinking water in concentrations that can harm to a variety of organisms. Therefore, several technologies are developed to treat these compounds, either for their complete removal or degradation in less toxic by-products. Some technologies applied to the treatment of EC, such as adsorption, advanced oxidative processes, membrane separation processes, and bioremediation through microalgal metabolism, were identified by thematic maps. Read More

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Few-Shot Induction of Generalized Logical Concepts via Human Guidance.

Front Robot AI 2020 18;7:122. Epub 2020 Nov 18.

Erik Jonsson School of Engineering and Computer Science (ECS), The University of Texas at Dallas, ECS, Dallas, TX, United States.

We consider the problem of learning generalized first-order representations of concepts from a small number of examples. We augment an inductive logic programming learner with 2 novel contributions. First, we define a distance measure between candidate concept representations that improves the efficiency of search for target concept and generalization. Read More

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November 2020

Adsorption of emerging contaminants from water and wastewater by modified biochar: A review.

Environ Pollut 2021 Jan 6;273:116448. Epub 2021 Jan 6.

Department of Agricultural and Biological Engineering, University of Florida, Gainesville, FL, 32611, USA.

Emerging contaminants (ECs), a group of relatively low-concentration but high-toxicity pollutants in the environment, have attracted widespread attention in recent years. These trace pollutants can be enriched in organisms and finally transferred to human bodies, posing a potential hazard to public health. Biochar, a low-cost and high-efficiency adsorbent, has been used to treat ECs in water. Read More

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January 2021

Glutathione and ethylene biosynthesis reveal that the glume and lemma have better tolerance to water deficit in wheat.

Plant Physiol Biochem 2021 Mar 12;160:120-129. Epub 2021 Jan 12.

College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, PR China. Electronic address:

As senescence progresses, the sensitivity of wheat organs to plant hormones during the grain-filling stages cannot be ignored. Especially under water deficit situation, non-leaf organs (spikes) have better photosynthesis and drought-tolerance traits than flag leaves. However, the mechanism of ethylene synthesis in wheat organs under water deficit remains unclear. Read More

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Delivery of siRNA to Endothelial Cells In Vivo Using Lysine/Histidine Oligopeptide-Modified Poly(β-amino ester) Nanoparticles.

Cardiovasc Eng Technol 2021 Feb 20;12(1):114-125. Epub 2021 Jan 20.

Grup d'Enginyera de Materials (GEMAT), Institut Químic de Sarrià, Universitat Ramon Llull, Via Augusta 390, 08017, Barcelona, Spain.

Purpose: Endothelial cell (EC) dysfunction underlies the pathology of multiple disease conditions including cardiovascular and pulmonary diseases. Dysfunctional ECs have a distinctive gene expression profile compared to healthy ECs. RNAi therapy is a powerful therapeutic approach that can be used to silence multiple genes of interests simultaneously. Read More

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February 2021

Generation of Functional Vascular Endothelial Cells and Pericytes from Keratinocyte Derived Human Induced Pluripotent Stem Cells.

Cells 2021 01 5;10(1). Epub 2021 Jan 5.

Institute of Neuroanatomy & Developmental Biology (INDB), Eberhard Karls University Tübingen, Österbergstrasse 3, 72074 Tübingen, Germany.

Human induced pluripotent stem cell (hiPSC)-derived endothelial cells (ECs) and pericytes provide a powerful tool for cardiovascular disease modelling, personalized drug testing, translational medicine, and tissue engineering. Here, we report a novel differentiation protocol that results in the fast and efficient production of ECs and pericytes from keratinocyte-derived hiPSCs. We found that the implementation of a 3D embryoid body (EB) stage significantly improves the differentiation efficiency. Read More

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January 2021

Hemodynamic Assessment of Hollow-Fiber Membrane Oxygenators Using Computational Fluid Dynamics in Heterogeneous Membrane Models.

J Biomech Eng 2021 Jan 19. Epub 2021 Jan 19.

Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Hannover Medical School, Germany; Department of Cardiothoracic, Transplantation and Vascular Surgery (HTTG), Hannover Medical School, Hannover, Germany; German Centre for Lung Research (DZL), BREATH, Hannover, Lower Saxony, Germany; Cardiopulmonary Regenerative Engineering (CARE) Group, Centre for Biological Engineering (CBE), Wolfson School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University, Loughborough, United Kingdom.

Extracorporeal membrane oxygenation (ECMO) has been used clinically for more than 40 years as a bridge to transplantation, with hollow-fiber membrane (HFM) oxygenators gaining in popularity due to their high gas transfer and low flow resistance. In spite of the technological advances in ECMO devices, the inevitable contact of the perfused blood with the polymer hollow-fiber gas-exchange membrane, and the subsequent thrombus formation, limits their clinical usage to only 2-4 weeks. In addition, the inhomogeneous flow in the device can further enhance thrombus formation and limit gas-transport efficiency. Read More

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January 2021

MnO -Based Materials for Environmental Applications.

Adv Mater 2021 Mar 14;33(9):e2004862. Epub 2021 Jan 14.

Department of Materials Science and Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, 999077, P. R. China.

Manganese dioxide (MnO ) is a promising photo-thermo-electric-responsive semiconductor material for environmental applications, owing to its various favorable properties. However, the unsatisfactory environmental purification efficiency of this material has limited its further applications. Fortunately, in the last few years, significant efforts have been undertaken for improving the environmental purification efficiency of this material and understanding its underlying mechanism. Read More

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Validation of an Analytical Workflow for the Analysis of Pesticide and Emerging Organic Contaminant Residues in Paddy Soil and Rice.

J Agric Food Chem 2021 Mar 11;69(11):3298-3306. Epub 2021 Jan 11.

Institute of Environmental Sciences, Boğaziçi University, Bebek, Istanbul 34342, Turkey.

Contamination of agricultural soil with organic contaminants is a global problem due to the risks associated with food security and ecological sustainability. Besides the use of agrochemicals, hundreds of emerging contaminants enter arable lands through polluted irrigation water. In this study, an analytical workflow based on QuEChERS extraction coupled with LC-MS/MS quantification was applied to measure 65 emerging contaminants (42 pesticides and 23 multiclass industrial chemicals) in soil and rice for the first time. Read More

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Performance Evaluation of Porous Graphene as Filter Media for the Removal of Pharmaceutical/Emerging Contaminants from Water and Wastewater.

Nanomaterials (Basel) 2021 Jan 1;11(1). Epub 2021 Jan 1.

College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter EX4 4QF, UK.

Graphene and its counterparts have been widely used for the removal of contaminants from (waste)water but with limited success for the removal of pharmaceutical contaminants. Driven by this need, this study reports, for the first time, the removal of pharmaceuticals from real contaminated water samples using porous graphene (PG) as a filter-based column. This work systematically evaluates the performance of PG as a filter medium for the removal of widely consumed pharmaceutical/emerging contaminants (ECs) such as atenolol, carbamazepine, ciprofloxacin, diclofenac, gemfibrozil and ibuprofen. Read More

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January 2021

Face Pose Alignment with Event Cameras.

Sensors (Basel) 2020 Dec 10;20(24). Epub 2020 Dec 10.

Event-Driven Perception for Robotics, Istituto Italiano di Tecnologia, 16163 Genova, Italy.

Event camera (EC) emerges as a bio-inspired sensor which can be an alternative or complementary vision modality with the benefits of energy efficiency, high dynamic range, and high temporal resolution coupled with activity dependent sparse sensing. In this study we investigate with ECs the problem of face pose alignment, which is an essential pre-processing stage for facial processing pipelines. EC-based alignment can unlock all these benefits in facial applications, especially where motion and dynamics carry the most relevant information due to the temporal change event sensing. Read More

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December 2020

MOF-derived core/shell C-TiO/CoTiO type II heterojunction for efficient photocatalytic removal of antibiotics.

J Hazard Mater 2021 Mar 26;406:124675. Epub 2020 Nov 26.

Guangdong Provincial Key Laboratory of Optical Information Materials and Technology & Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangdong, China. Electronic address:

A novel core/shell C-TiO/CoTiO type II heterojunction was successfully synthesized via a direct calcination method by using MIL-125/Co core-shell nanocakes as a sacrificial template and precursor. In the calcination process, the organic ligand in MIL-125 acts as an in-situ carbon doping source to form a carbon-doped TiO core (C-TiO). At the same time, CoTiO nanoparticles are formed on the surface of C-TiO by an in-situ solid-state reaction between the C-TiO and Co shell of MIL-125/Co. Read More

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Hypoxia as a Driving Force of Pluripotent Stem Cell Reprogramming and Differentiation to Endothelial Cells.

Biomolecules 2020 11 29;10(12). Epub 2020 Nov 29.

Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Kraków, Poland.

Inadequate supply of oxygen (O) is a hallmark of many diseases, in particular those related to the cardiovascular system. On the other hand, tissue hypoxia is an important factor regulating (normal) embryogenesis and differentiation of stem cells at the early stages of embryonic development. In culture, hypoxic conditions may facilitate the derivation of embryonic stem cells (ESCs) and the generation of induced pluripotent stem cells (iPSCs), which may serve as a valuable tool for disease modeling. Read More

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November 2020

Reliable, High-Performance Electrochromic Supercapacitors Based on Metal-Doped Nickel Oxide.

ACS Appl Mater Interfaces 2020 Nov 9;12(46):51978-51986. Epub 2020 Nov 9.

Department of Chemical Engineering, University of Seoul, Seoul 02504, Republic of Korea.

Herein, high-performance, reliable electrochromic supercapacitors (ECSs) are proposed based on tungsten trioxide (WO) and nickel oxide (NiO) films. To maximize device performance and stability, the stoichiometric balance between anode and cathode materials is controlled by carefully adjusting the thickness of the anodic NiO film while fixing the thickness of WO to ∼660 nm. Then, a small amount (≤10 mol %) of metal (e. Read More

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November 2020

Comparison of Efficiency and Function of Vascular Endothelial Growth Factor Adenovirus Vectors in Endothelial Cells for Gene Therapy of Placental Insufficiency.

Hum Gene Ther 2020 11;31(21-22):1190-1202

Elizabeth Garrett Anderson Institute for Women's Health.

Severe fetal growth restriction (FGR) affects 1:500 pregnancies, is untreatable and causes serious neonatal morbidity and death. Reduced uterine blood flow (UBF) and lack of bioavailable VEGF due to placental insufficiency is a major cause. Transduction of uterine arteries in normal or FGR sheep and guinea pigs using an adenovirus (Ad) encoding isoforms A (Ad. Read More

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November 2020

Treatment technologies for emerging contaminants in wastewater treatment plants: A review.

Sci Total Environ 2021 Jan 26;753:141990. Epub 2020 Aug 26.

Department of Civil and Environmental Engineering, University of Nebraska-Lincoln, Omaha, NE 68182, USA; Global Institute for Energy, Environment and Sustainability, Kansas, USA. Electronic address:

The "emerging contaminants" (ECs) are predominantly unregulated anthropogenic chemicals that occur in air, soil, water, food, and human/animal tissues in trace concentrations. The ECs are persistent in the environment, capable of perturbing the physiology of target receptors and, therefore, are regarded as contaminants of emerging environmental concerns in recent years. The prominent classes of ECs include pharmaceuticals and personal care products (PCPs), surfactants, plasticizers, pesticides, fire retardants, and nanomaterials. Read More

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January 2021

A systematic approach of method development for analysis of multiple classes of emerging contaminants in wastewater: a case study of a biological nutrient removal based plant.

Anal Methods 2020 09;12(35):4363-4376

Department of Civil Engineering, Indian Institute of Technology, Roorkee, Roorkee, Uttarakhand, India.

Pharmaceuticals, personal care products, synthetic hormones, and industrial manufacturing additives are used worldwide, and their residues are frequently detected in wastewater. In this study, a sensitive and selective method was developed and validated for the detection and quantification of 14 Emerging Contaminants (ECs) with various physico-chemical properties frequently found in wastewater. Solid Phase Extraction (SPE) allowed for extraction and concentration of the compounds. Read More

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September 2020

TGase-mediated cell membrane modification and targeted cell delivery to inflammatory endothelium.

Biomaterials 2021 Feb 6;269:120276. Epub 2020 Aug 6.

Department of Biomedical Engineering, School of Medicine, Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084, China. Electronic address:

Targeted cell delivery to lesion sites via minimally invasive approach remains an unmet need in regenerative medicine to endow controlled cell distribution and minimized side-effects. Current cell modification approaches to improve cell delivery tend to have adverse effects on cellular phenotype and functionality. Here, we rationally developed a facile and mild cell modification and targeted delivery strategy leveraging endogenous tissue transglutaminase (TGase) expressed on the surface of MSCs (Mesenchymal Stem Cells) and inflammatory endothelial cells (ECs). Read More

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February 2021

Dietary γ-Glutamyl Valine Ameliorates TNF-α-Induced Vascular Inflammation Endothelial Calcium-Sensing Receptors.

J Agric Food Chem 2020 Aug 13;68(34):9139-9149. Epub 2020 Aug 13.

Department of Food Science and Technology, University of Nebraska-Lincoln, Lincoln 68588, Nebraska, United States.

γ-Glutamyl valine (γ-EV), commonly found in edible beans, was shown to reduce gastrointestinal inflammation activation of calcium-sensing receptors (CaSRs). The present study aimed to evaluate the efficacy of γ-EV in modulating the tumor necrosis factor-α-induced inflammatory responses in endothelial cells (ECs) CaSR-mediated pathways. Human aortic ECs (HAoECs) were pretreated (2 h) with γ-EV (0. Read More

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