15,432 results match your criteria effects probiotic


Effects of alkali, enzymes, and ultrasound on monosodium glutamate byproduct for a sustainable production of Bacillus subtilis.

Food Chem 2021 Apr 27;360:129967. Epub 2021 Apr 27.

Institute of Food Science and Technology, College of Biological Science and Engineering, Fuzhou University, 350108 Fuzhou, China; Fujian Center of Excellence for Food Biotechnology, 350108 Fuzhou, China.

Due to the hindrance of flocculated polymers and bacterial cell wall, the production of Bacillus subtilis using monosodium glutamate byproduct (MSGB) was low. With the assistance of scanning electron microscope images, effects of alkali, lysozyme, papain, ultrasound, and their combinations on MSGB were evaluated using the results of soluble protein, carbohydrate, monosaccharides and peptidoglycans. Alkali could dissolve flocculated polymers increasing 21% soluble MSGB, and thus enhanced the subsequent treatments (ultrasound, lysozyme, or papain) to increase 14-17% soluble MSGB. Read More

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Serum cytokine patterns are modulated in infants fed formula with probiotics or milk fat globule membranes: A randomized controlled trial.

PLoS One 2021 13;16(5):e0251293. Epub 2021 May 13.

Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.

Background: Proteins and lipids of milk fat globule membrane (MFGM) and probiotics are immunomodulatory. We hypothesized that Lactobacillus paracasei ssp. paracasei strain F19 (F19) would augment vaccine antibody and T helper 1 type immune responses whereas MFGM would produce an immune response closer to that of breastfed (BF) infants. Read More

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Preliminary evaluation of probiotic effects on gastrointestinal signs in dogs with multicentric lymphoma undergoing multi-agent chemotherapy: A randomised, placebo-controlled study.

Vet Rec Open 2021 Dec 29;8(1):e2. Epub 2021 Mar 29.

Department of Clinical Sciences College of Veterinary Medicine Kansas State University Manhattan Kansas USA.

Background: Gastrointestinal (GI) toxicity is a major dose-limiting factor in dogs undergoing chemotherapy. A proposed mechanism of GI toxicity includes chemotherapy-driven GI dysbiosis. This study was designed to determine the effects of probiotic administration on GI side-effects in dogs receiving multi-agent chemotherapy. Read More

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December 2021

Oral colonization by KABPTM-052 and KABPTM-051: A Randomized, Double-Blinded, Placebo-Controlled Trial (Pilot Study).

J Clin Exp Dent 2021 May 1;13(5):e433-e439. Epub 2021 May 1.

AB-Biotics SA, Barcelona, Spain.

Background: To determine the oral colonization capacity of the strains KABPTM-052 (CECT 7480) and KABPTM-051 (CECT 7481) in healthy subjects.

Material And Methods: This randomized, double-blinded, placebo-controlled study included 40 volunteers (22 females, 18 males; age range 18-55 years) with healthy gingiva or mild gingivitis, allocated to receiving probiotic chewing gum (n=20) or placebo (n=20) b.i. Read More

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Supplementation of Lactobacillus early in life alters attention bias to threat in piglets.

Sci Rep 2021 May 12;11(1):10130. Epub 2021 May 12.

Department of Animal Environment and Health, Swedish University of Agricultural Sciences, Box 7068, 750 07, Uppsala, Sweden.

Gut microbes play an important role in regulating brain processes and influence behaviour, cognition and emotional states in humans and rodents. Nevertheless, it is not known how ingestion of beneficial microbes modulates emotional states in piglets and whether it can improve welfare. Here we use an attention bias task to assess the effects of Lactobacillus reuteri ATCC-PTA-6475 and Lactobacillus plantarum L1-6 supplementation early in life on emotional states in 33 piglets compared to 31 placebo supplemented piglets. Read More

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Anticancer effects of bifidobacteria on colon cancer cell lines.

Cancer Cell Int 2021 May 12;21(1):258. Epub 2021 May 12.

Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Colorectal cancer (CRC), with a growing incidence trend worldwide, is resistant to apoptosis and has uncontrolled proliferation. It is recently reported that probiotic microorganisms exert anticancer effects. The genus Bifidobacterium, one of the dominant bacterial populations in the gastrointestinal tract, has received increasing attention because of widespread interest in using it as health-promoting microorganisms. Read More

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Potential beneficial effects of kefir and its postbiotic, kefiran, on child food allergy.

Food Funct 2021 May;12(9):3770-3786

Laboratory of Pharmaceutical and Medicinal Chemistry (PharMedChem), Federal University of Amapá, Macapá, Brazil.

Food allergies are known as the public health problem, affecting people of all age groups, but more commonly in babies and children, with consequences for nutritional status and quality of life. The increase in the consumption of healthy foods has consequently led to an increased demand for functional foods with specific health benefits. Thus, the pharmaceutical industry's interest in natural products has grown every time and is therefore considered as an alternative to synthetic drugs. Read More

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Treatment of chronic airway diseases using nutraceuticals: Mechanistic insight.

Crit Rev Food Sci Nutr 2021 May 12:1-15. Epub 2021 May 12.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.

Respiratory diseases, both acute and chronic, are reported to be the leading cause of morbidity and mortality, affecting millions of people globally, leading to high socio-economic burden for the society in the recent decades. Chronic inflammation and decline in lung function are the common symptoms of respiratory diseases. The current treatment strategies revolve around using appropriate anti-inflammatory agents and bronchodilators. Read More

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Comparative Evaluation of Antibacterial Activity of Probiotics SK12 and SM18: An Study.

Int J Clin Pediatr Dent 2020 Nov-Dec;13(6):611-616

Department of Pediatric and Preventive Dentistry, Coorg Institute of Dental Sciences, Virajpet, Karnataka, India.

Aim: To assess the antimicrobial activity of probiotics SK12 and SM18 on and also to compare the antimicrobial activity of SK12 and SM18.

Materials And Methods: Synthetic strains of were used to study the antimicrobial activity of probiotics SK12 and SM18 using various tests such as disk diffusion, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC). In disk diffusion, the zone of inhibition was measured to assess the antimicrobial activity. Read More

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Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease.

Neurosci Lett 2021 May 8:135949. Epub 2021 May 8.

Department of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.

It has been suggested that gut microbiota dysbiosis can lead to Alzheimer's disease (AD), inducing the production of many AD-related pre-inflammatory cytokines. On the other hand, daily probiotic administration and regular exercise training are assumed to improve clinical AD-related symptoms. To take this line of research further, this study was aimed at investigating the impact of moderate-intensity interval training (MIIT) with a combined administration of Lactobacillus plantarum and Bifidobacterium bifidum (probiotic, BROB) on the passive avoidance test (Shuttle Box), choline acetyltransferase (ChAT) and the brain derived neurotrophic factor (BDNF) in the hippocampus of a rat model of AD. Read More

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Effects of Gasterophilus pecorum infestation on the intestinal microbiota of the rewilded Przewalski's horses in China.

PLoS One 2021 11;16(5):e0251512. Epub 2021 May 11.

Department of Civil and Environmental Engineering, University of Macau, Macao, China.

Horse botflies have been a threat to the Przewalski's horses in the Kalamaili Nature Reserve in Xinjiang of China since their reintroduction to the original range. As larvae of these parasites could infest the intestine of a horse for months, they could interact with and alter the structure and composition of its intestinal microbiota, affecting adversely its health. Nonetheless, there are no such studies on the rewilded Przewalski's horses yet. Read More

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Short-term intake of ZDY2013 fermented milk promotes homoeostasis of gut microbiota under enterotoxigenic challenge.

Food Funct 2021 May 11. Epub 2021 May 11.

State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 30047, China. and Sino-German Joint Research Institute, Nanchang University, Nanchang 30047, China.

Probiotics have long been used as functional starter cultures for fermented foods and are associated with numerous health benefits. Lactiplantibacillus (L.) plantarum ZDY2013 is an acid-tolerant probiotic candidate owning antagonistic properties against the food-borne pathogen Bacillus (B. Read More

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Shift in skin microbiota and immune functions of zebrafish after combined exposure to perfluorobutanesulfonate and probiotic Lactobacillus rhamnosus.

Ecotoxicol Environ Saf 2021 May 7;218:112310. Epub 2021 May 7.

State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China. Electronic address:

Dysbiosis of fish skin microbiome and immunity by environmental pollutants are rarely studied in toxicological research in spite of their importance for fish health. In the present study, adult zebrafish were exposed to 0 and 10 μg/L of perfluorobutanesulfonate (PFBS) for 40 days, with or without the supplementation of probiotic Lactobacillus rhamnosus, with objectives to explore the interaction between PFBS pollutant and probiotic bacteria on skin mucosal microbiota and immune response. Amplicon sequencing analysis found that PFBS alone significantly disturbed the microbial community composition and abundance on the skin, favoring the growth of stress-tolerant bacteria (e. Read More

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Overview of the latest developments in the role of probiotics, prebiotics and synbiotics in shrimp aquaculture.

Fish Shellfish Immunol 2021 May 7. Epub 2021 May 7.

Ocean College, Zhejiang University, Zhoushan, 316021, China. Electronic address:

With the growing world population, the demand for food has increased, leading to excessive and intensive breeding and cultivation of fisheries, simultaneously exacerbating the risk of disease. Recently, shrimp producers have faced major losses of stocks due to the prevalence of periodical diseases and inappropriate use of antibiotics for disease prevention and treatment, leading to bacterial resistance in shrimp, along with imposing health hazards on human consumers. Strict regulations have been placed to ban or reduce the use of prophylactic antibiotics to lessen their detrimental effects on aquatic life. Read More

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Oral immunization with recombinant Lactobacillus plantarum expressing Nudix hydrolase and 43 kDa proteins confers protection against Trichinella spiralis in BALB/c mice.

Acta Trop 2021 May 7:105947. Epub 2021 May 7.

College of Veterinary Medicine, Jilin Agricultural University, Changchun, China; Jilin Provincial Engineering Research Center of Animal Probiotics, Jilin Agricultural University, Changchun, China; Key Laboratory of animal production and product quality safety of Ministry of Education, Jilin Agricultural University, Changchun, China. Electronic address:

Trichinellosis is a significant food-borne zoonotic parasitic disease caused by parasite Trichinella. Given the side effects of anti-Trichinella drugs (e.g. Read More

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Antimicrobial properties of Lactobacillus cell-free supernatants against multidrug-resistant urogenital pathogens.

Microbiologyopen 2021 Feb;10(2):e1173

Department of Biomedical and Biotechnological Sciences, Microbiology Section, University of Catania, Catania, Italy.

The healthy vaginal microbiota is dominated by Lactobacillus spp., which provide an important critical line of defense against pathogens, as well as giving beneficial effects to the host. We characterized L. Read More

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February 2021

Role of probiotics in prevention and treatment of enteric infections: a comprehensive review.

3 Biotech 2021 May 27;11(5):242. Epub 2021 Apr 27.

Faculty of Applied Sciences and Biotechnology, School of Biotechnology, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh India.

Microorganisms that inhabits human digestive tract affect global health and enteric disorders. Previous studies have documented the effectiveness and mode of action of probiotics and classified as human-friendly biota and a competitor to enteric pathogens. Statistical studies reported more than 1. Read More

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Effectiveness of Probiotic, Prebiotic, and Synbiotic Supplementation to Improve Perinatal Mental Health in Mothers: A Systematic Review and Meta-Analysis.

Front Psychiatry 2021 22;12:622181. Epub 2021 Apr 22.

Department of Obstetrics & Gynecology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

There is an emerging interest in modulating the gut microbiota to target the gut-brain axis and improve maternal mental health in the perinatal period. This systematic review evaluated the effectiveness of prebiotics, probiotics, and synbiotics supplementation during pregnancy to reduce the risk of maternal mental health problems in the perinatal period. Electronic biomedical databases and clinical trial registries were searched from database inception through August 2020 to identify randomized controlled clinical trials (RCTs) evaluating the effect of probiotic, prebiotic, or synbiotic supplements administered to women during pregnancy on measures of perinatal depression, anxiety, and other mental health outcomes. Read More

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Edible Bird's Nest Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in C57BL/6J Mice by Restoring the Th17/Treg Cell Balance.

Front Pharmacol 2021 21;12:632602. Epub 2021 Apr 21.

Guangdong Key Laboratory for Research and Development of Natural Drugs, Key Laboratory of Research and Development of New Medical Materials of Guangdong Medical University, School of Pharmacy, Guangdong Medical University, Dongguan, China.

Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) with a complex aetiology that commonly recurs. Most drugs for UC treatment interfere with metabolism and immune responses, often causing some serious adverse reactions. Therefore, the development of alternative treatments, including nutritional supplements and probiotics, have been one of the main areas of current research due to fewer side effect. Read More

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Significance and effects of prenatal and postnatal microbiome in the period of early individual development and options for interventional treatment

Orv Hetil 2021 05 9;162(19):731-740. Epub 2021 May 9.

3 Semmelweis Egyetem, Általános Orvostudományi Kar, I. Gyermekgyógyászati Klinika, Budapest.

Összefoglaló. A humán mikrobiom az emberi szervezetben és az emberi testfelszínen élő mikrobaközösségek összessége, amelyek többsége a gyomor-bél rendszerben él. Ezek a mikrobaközösségek számos és sokféle baktériumot tartalmaznak, gombákat, vírusokat, archeákat és protozoonokat. Read More

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Milk Kefir therapy reduces inflammation and alveolar bone loss on periodontitis in rats.

Biomed Pharmacother 2021 May 6;139:111677. Epub 2021 May 6.

Post Graduate Program in Morphofunctional Sciences, Department of Morphology, Federal University of Ceará, Fortaleza, Ceará, Brazil; Post Graduate Program in Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil. Electronic address:

Periodontitis is a chronic inflammatory disease that affects the tooth-supporting tissues. This study evaluated the anti-inflammatory and antiresorptive effects of milk kefir (MK) on periodontitis in rats. Micro-Raman spectroscopy was performed on MK at different fermentation times to verify the presence of Lactobacillus kefiri. Read More

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Lactobacillus rhamnosus GG defense against Salmonella enterica serovar Typhimurium infection through modulation of M1 macrophage polarization.

Microb Pathog 2021 May 6;156:104939. Epub 2021 May 6.

College of Veterinary Medicine, Jilin Agricultural University, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Changchun, China. Electronic address:

Lactobacillus rhamnosus GG (LGG), a model probiotic strain, plays an important role in immune regulatory activity to prevent and treat intestinal inflammation or diarrhea. However, the effect of the immune modulation of LGG on macrophages to prevent Salmonella infection has not been thoroughly studied. In this study, C57BL/6 mice were pre-administered LGG for 7 days continuously, and then infected with Salmonella enterica subsp. Read More

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strains producing selected bacteriocins inhibit porcine enterotoxigenic (ETEC) both under and conditions.

Appl Environ Microbiol 2021 May 7. Epub 2021 May 7.

Department of Biology, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic

Enterotoxigenic (ETEC) and Shiga toxin-producing (STEC) strains are the causative agents of severe foodborne diseases in both humans and animals. In this study, porcine pathogenic strains (n = 277) as well as porcine commensal strains (n = 188) were tested for their susceptibility to 34 bacteriocin monoproducers to identify the most suitable bacteriocin types inhibiting porcine pathogens. Under condition, the set of pathogenic was found to be significantly more susceptible to a majority of tested bacteriocins when compared to commensal Based on production of bacteriocins with specific activity against pathogen, three potentially probiotic commensal strains of human origin were selected. Read More

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Effects of LI05 on immunity and metabolism in germ-free rats.

Food Funct 2021 May 7. Epub 2021 May 7.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Many Pediococcus spp. have health-promoting benefits, and Pediococcus pentosaceus LI05 is one such species that was proved to be beneficial in previous studies. Our research aimed to determine the immune and metabolic effects of P. Read More

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Application of the Combination of Soybean Lecithin and Whey Protein Concentrate 80 to Improve the Bile Salt and Acid Tolerance of Probiotics.

J Microbiol Biotechnol 2021 May 7;31(1). Epub 2021 May 7.

Yunnan Huangshi Lesson Dairy Industry Co., Ltd, Dali 671000, P.R. China.

To improve the bile salt and acid tolerance of probiotics against gastrointestinal stresses, we investigated the effects of soybean lecithin and whey protein concentrate (WPC) 80 on the bile salt tolerance of L9 using a single factor methodology and optimized the method using response surface methodology (RSM). The survival rate of L9 treated with 0.3% (w/v) bile salt for 2. Read More

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Survivability and controlled release of alginate-microencapsulated Pseudomonas fluorescens VUPF506 and their effects on biocontrol of Rhizoctonia solani on potato.

Int J Biol Macromol 2021 May 3;183:627-634. Epub 2021 May 3.

Department of Plant Protection, Faculty of Agricultural Sciences, Vali-e-Asr University of Rafsanjan, Iran.

Preserving the efficacy of plant probiotic bacteria in soil is a major challenge to the biological control of plant diseases. The microencapsulation technique is an important step in preserving the viability and activity of probiotics in adverse environmental conditions. The main objective of this study was to choose an appropriate coating for probiotic encapsulation. Read More

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Probiotic Supplementation Improved Capecitabine Protective Effect against Gastric Cancer Growth in Male BALB/c Mice.

Nutr Cancer 2020 Oct 14:1-11. Epub 2020 Oct 14.

Department of Pathology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.

The gastric cancer (GC) is biologically and genetically heterogeneous with a poorly understood carcinogenesis at the molecular level. Herein, we studied the effects of probiotics () on subcutaneous implantation of xenograft GC. Moreover, the effect of probiotics () was compared with the capecitabine drug as known used drug against GC. Read More

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October 2020

Gut microbiota in mental health and depression: role of pre/pro/synbiotics in their modulation.

Food Funct 2021 May 6. Epub 2021 May 6.

Healthy Gut Research Group, Centre of Excellence in Functional Food Research, Department of Food and Nutritional Biotechnology, National Agri-Food Biotechnology Institute, SAS Nagar, 140306, Punjab, India.

The microbiome residing in the human gut performs a wide range of biological functions. Recently, it has been elucidated that a change in dietary habits is associated with alteration in the gut microflora which results in increased health risks and vulnerability towards various diseases. Falling in line with the same concept, depression has also been shown to increase its prevalence around the globe, especially in the western world. Read More

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Short-chain fatty acids-producing probiotics: A novel source of psychobiotics.

Crit Rev Food Sci Nutr 2021 May 6:1-31. Epub 2021 May 6.

Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Psychobiotics-live microorganisms with potential mental health benefits, which can modulate the microbiota-gut-brain-axis via immune, humoral, neural, and metabolic pathways-are emerging as novel therapeutic options for the effective treatment of psychiatric disorders Recently, microbiome studies have identified numerous putative psychobiotic strains, of which short-chain fatty acids (SCFAs) producing bacteria have attracted special attention from neurobiologists. Recent studies have highlighted that SCFAs-producing bacteria such as , and have a very specific function in various psychiatric disorders, suggesting that these bacteria can be potential novel psychobiotics. SCFAs, potential mediators of microbiota-gut-brain axis, might modulate function of neurological processes. Read More

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