412 results match your criteria edo populations

Linkage disequilibrium patterns, population structure and diversity analysis in a worldwide durum wheat collection including Argentinian genotypes.

BMC Genomics 2021 Apr 5;22(1):233. Epub 2021 Apr 5.

Centro de Recursos Naturales Renovables de la Zona Semiárida (CERZOS), Departamento de Agronomía, Universidad Nacional del Sur (UNS)-CONICET, Bahía Blanca, Argentina.

Background: Durum wheat (Triticum turgidum L. ssp. durum Desf. Read More

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Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial.

Lancet Oncol 2021 Mar 30. Epub 2021 Mar 30.

Department of Medical Oncology, The Christie NHS Foundation Trust/Institute of Cancer Sciences, University of Manchester, Manchester, UK; Division of Cancer Sciences, University of Manchester, Manchester, UK. Electronic address:

Background: Advanced biliary tract cancer has a poor prognosis. Cisplatin and gemcitabine is the standard first-line chemotherapy regimen, but no robust evidence is available for second-line chemotherapy. The aim of this study was to determine the benefit derived from second-line FOLFOX (folinic acid, fluorouracil, and oxaliplatin) chemotherapy in advanced biliary tract cancer. Read More

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Dietary pattern and nutritional status of female adolescents in Amai Secondary School, Delta State, Nigeria.

Pan Afr Med J 2021 13;38:32. Epub 2021 Jan 13.

Department of Public and Community Health, Novena University Ogume, Delta State, Nigeria.

Introduction: there is an existing variability in eating patterns between adolescents and children. Consequently, with the adoption of westernised way of life, this translates to a change in eating habits and food choices. This study was designed to investigate the dietary patterns and nutritional status of the female adolescents in Amai Secondary Commercial School, Delta State, Nigeria. Read More

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Individual and familial factors associated with caries and gingivitis among adolescents resident in a semi-urban community in South-Western Nigeria.

BMC Oral Health 2021 Mar 27;21(1):166. Epub 2021 Mar 27.

International Research Center of Excellence, Institute of Human Virology Nigeria, Abuja, Federal Capital Territory, Nigeria.

Objectives: We describe the prevalence, and individual and familial risk indicators for dental caries and gingivitis among 10-19-year-old adolescents in Ile-Ife, South-West Nigeria.

Methods: This cross-sectional study collected data through household surveys conducted between December 2018 and January 2019. Adolescents were recruited through multistage sampling. Read More

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Relevance of Rheumatic Valvular Heart Disease in the Aetiology of Heart Failure in Contemporary Times.

West Afr J Med 2021 03;38(3):241-245

Faculty of Clinical Medicine, Delta State University, Abraka; and Department of Medicine, Delta State University Teaching Hospital, Oghara, Delta State, Nigeria.

Background: Rheumatic valvular heart disease (RVHD) is one of the foremost causes of heart failure (HF) in our population, particularly among young adults, but a decline in the prevalence of RVHD has been observed. The effect of this decline on the relevance of RVHD among other causes of HF is not established in our setting.

Objective: To determine whether RVHD is still a leading cause of HF in our population or not. Read More

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Additive genetic variance and covariance between relatives in synthetic wheat crosses with variable parental ploidy levels.

Genetics 2021 Feb;217(2)

Departamento de Producción Animal, Facultad de Agronomía, Universidad de Buenos Aires. Instituto de Investigaciones en Producción Animal (INPA), Consejo Nacional de Investigaciones Científicas y Técnicas, 1417 Ciudad Autónoma de Buenos Aires, Argentina.

Cultivated bread wheat (Triticum aestivum L.) is an allohexaploid species resulting from the natural hybridization and chromosome doubling of allotetraploid durum wheat (T. turgidum) and a diploid goatgrass Aegilops tauschii Coss (Ae. Read More

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February 2021

Community mitigation strategies for coronavirus disease 2019: An assessment of knowledge and adherence amongst residents of Benin City, Edo State, Nigeria.

Niger Postgrad Med J 2021 Jan-Mar;28(1):14-21

Department of Community Health, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria.

Background: In the absence of effective vaccines and definitive treatment, non-pharmaceutical interventions, also known as community mitigation strategies (CMS), are needed to reduce the transmission of respiratory virus infections such as coronavirus disease 2019 (COVID-19). However, the effectiveness of these strategies depends on a knowledgeable population cooperating and adhering strictly to recommended strategies.

Objective: The objective of the study was to determine the knowledge and adherence to CMS against COVID-19 in Benin City, the capital of Edo State, Nigeria. Read More

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Ensuring access to COVID-19 vaccines among marginalised populations in Africa.

Public Health 2021 Jan 26. Epub 2021 Jan 26.

Department of Public Health Medicine, School of Public Health and Nursing, University of KwaZulu-Natal, Durban, South Africa.

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January 2021

Mean glandular dose in the mammary gland and dose of radiation in the thyroid gland and lens in women with and without breast implants during different modalities of mammography.

Radiologia 2021 Feb 3. Epub 2021 Feb 3.

Instituto Venezolano de Investigaciones Científicas, Edo, Miranda, Venezuela.

There have always been concerns about the secondary effects of diagnostic methods that use ionizing radiation. During mammography, the parameters to be concerned about are the mean glandular dose and the scatter dose. We evaluated the dose of radiation to the breast, thyroid gland, and lens in digital mammography in women with and without implants, in tomosynthesis in women with and without implants, and in contrast-enhanced mammography. Read More

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February 2021

Early-Onset Parkinson Disease Screening in Patients From Nigeria.

Front Neurol 2020 14;11:594927. Epub 2021 Jan 14.

Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, United States.

Nigeria is one of the most populated countries in the world; however, there is a scarcity of studies in patients with age-related neurodegenerative diseases, such as Parkinson disease (PD). The aim of this study was to screen patients with PD including a small cohort of early-onset PD (EOPD) cases from Nigeria for multiplication, and LRRK2 p.G2019S. Read More

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January 2021

A proposed one-stop-shop approach for the delivery of integrated oral, mental, sexual and reproductive healthcare to adolescents in Nigeria.

Pan Afr Med J 2020 21;37:172. Epub 2020 Oct 21.

Department of Mental Health, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.

The interconnectedness of oral, mental, sexual, and reproductive health (OMSRH) in adolescents prompts exploration of novel approaches to facilitate comprehensive access of this population to the relevant health services. This paper proposes an integrated one-stop-shop approach to increasing adolescents' access to OMSRH care by leveraging on dental clinics as a template for integration, using a non-stigmatized platform to deliver stigmatized healthcare. Novel healthcare delivery models are needed to enhance adolescents' access to the comprehensive prevention and treatment services that they critically need. Read More

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January 2021

Awareness and uptake of human papilloma virus vaccines among female secondary school students in Benin City, Nigeria.

Afr Health Sci 2020 Mar;20(1):45-50

Department of Obstetrics and Gynaecology, University of Benin Teaching Hospital, Benin City, Edo state, Nigeria.

Background: There is no Government endorsed HPV vaccine immunisation program in Nigeria. The Vaccine has been available at the University of Benin Teaching Hospital (UBTH) in Benin City for more than 7 years.

Objectives: The aim was to evaluate awareness about HPV, the prevalence of HPV immunisation and its associated factors among the study population. Read More

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Effect of microbial feed additives on growth performance, microbial protein synthesis, and rumen microbial population in growing lambs.

Transl Anim Sci 2020 Oct 8;4(4):txaa203. Epub 2020 Nov 8.

Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca, Edo de México, México.

Arabi lambs ( =28; body weight = 24 ± 3.7 kg; average age = 120 ± 8 days) were used to investigate the effect of microbial additives on growth performance, microbial protein synthesis and rumen microbial population of fattening lamb based on completely randomized design. Four treatments were studied: (1) control (without additive; CON); (2) and (FP); (3) (SC) plus FP (SCFP); and (4) plus SCFP (MSCFP). Read More

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October 2020

Addressing disparities and challenges in underserved patient populations with metastatic breast cancer in Europe.

Breast 2021 Feb 13;55:79-90. Epub 2020 Dec 13.

ABC Global Alliance, C/o Champalimaud Foundation, Av. Brasília, Lisbon, 1400-038, Portugal; Breast Unit, Champalimaud Clinical Center/Champalimaud Foundation, Lisbon, Portugal. Electronic address:

People with metastatic breast cancer face many challenges and disparities in obtaining optimal cancer care. These challenges are accentuated in underserved patient populations across Europe, who are less likely to receive quality healthcare for reasons including socioeconomic inequalities, educational or cultural status, or geographic location. While there are many local and national initiatives targeted to address these challenges, there remains a need to reduce disparities and improve access to healthcare to improve outcomes, with a focus on multidisciplinary stakeholder engagement. Read More

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February 2021

Relative Incidence and Demographics of Blepharoptosis Subtypes in a Tertiary Care Centre, South-South, Nigeria.

West Afr J Med 2020 Dec;37(7):796-800

Department of Ophthalmology, University of Benin, Benin City, Edo State, Nigeria.

Purpose: To determine the types of blepharoptosis and demographics of patients referred to the ophthalmology clinic of the University of Benin Teaching Hospital, thereby providing data on the common types of blepharoptosis within an indigenous Nigerian population.

Methods: A hospital-based retrospective chart review of all patients who presented with blepharoptosis from March 2015 to June 2019. Data on age, gender, affected eye, severity and aetiology of blepharoptosis was obtained. Read More

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December 2020

An Analysis of COVID-19 Patients Receiving Care in a Tertiary Facility in Southern Nigeria.

West Afr J Med 2020 Dec;37(7):715-720

Nursing Services, University of Benin Teaching Hospital, Benin City, PMB 1111, Edo State,Nigeria.

Background: Information pertaining to the clinical characteristics of COVID-19 in sub-Saharan Africa remains sparse. In Nigeria, it is limited to few isolated reports and case series confined to the early phase of the outbreak. The objective of this study is to describe the presenting characteristics, co-morbidities and outcomes of Nigerian patients managed over a 3-month period in a tertiary hospital. Read More

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December 2020

Self-medication practice with antimalarials & the determinants of malaria treatment-seeking behavior among postpartum mothers in a rural community in Nigeria.

Pharmacoepidemiol Drug Saf 2021 Apr 15;30(4):435-444. Epub 2020 Dec 15.

Department of Zoology, Faculty of Life Sciences, Ambrose Alli University, Ekpoma, Edo State, Nigeria.

Background: The majority of the population has inappropriate malaria treatment-seeking behavior and little is known about self-medication practice with antimalarials among postpartum mothers.

Aim & Objectives Of Study: The study, therefore, aims to determine the prevalence of self-treatment practice with antimalarials and identify factors that determine inappropriate treatment-seeking practice in this susceptible group.

Research Methods: The study is a cross-sectional study that was conducted using a purposive sampling technique. Read More

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Adaptive selection drives TRPP3 loss-of-function in an Ethiopian population.

Sci Rep 2020 12 2;10(1):20999. Epub 2020 Dec 2.

Laboratory of Molecular Physiology, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003, Barcelona, Spain.

TRPP3 (also called PKD2L1) is a nonselective, cation-permeable channel activated by multiple stimuli, including extracellular pH changes. TRPP3 had been considered a candidate for sour sensor in humans, due to its high expression in a subset of tongue receptor cells detecting sour, along with its membership to the TRP channel family known to function as sensory receptors. Here, we describe the functional consequences of two non-synonymous genetic variants (R278Q and R378W) found to be under strong positive selection in an Ethiopian population, the Gumuz. Read More

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December 2020

Accuracy of fine needle aspiration cytology in the preoperative diagnosis of malignant non-odontogenic tumors of the orofacial region.

Diagn Cytopathol 2021 Mar 16;49(3):381-387. Epub 2020 Nov 16.

Department of Oral Pathology and Medicine, University of Benin, Benin City, Edo State, Nigeria.

Background: This study aims to determine the association between preoperative cytopathological diagnosis and the histopathological diagnosis of orofacial non-odontogenic tumors. It is also, to determine the sensitivity, specificity and accuracy of fine needle aspiration cytology (FNAC) in the preoperative diagnosis of orofacial malignant non-odontogenic tumors in a Nigerian population.

Methods: A 9-month prospective study in which preoperative FNAC followed by open biopsy for confirmatory histopathological evaluation was performed for consenting patients with orofacial swellings. Read More

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Population risk factors for COVID-19 deaths in Nigeria at sub-national level.

Pan Afr Med J 2020 4;35(Suppl 2):131. Epub 2020 Aug 4.

Department of Medical Microbiology and Immunology, College of Medicine and Health Sciences, United Arab Emirates University, United Arab Emirates.

Introduction: Nigeria is the most populous country in the African continent. The aim of this study was to analyze risk factors for COVID-19 prevalence and deaths in all 6 geopolitical regions and 37 States in Nigeria.

Methods: we analyzed the data retrieved from various sources, including Nigeria CDC, Nigeria National Bureau of Statistics, Unicef-Nigeria multiple indicator cluster survey and the Institute of Health Metrics and Evaluation, University of Washington. Read More

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November 2020

NOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin.

Nat Commun 2020 10 12;11(1):5126. Epub 2020 Oct 12.

Department of Biochemistry, University of Lausanne, 1066, Epalinges, Switzerland.

Cancer associated fibroblasts (CAFs) are a key component of the tumor microenvironment. Genomic alterations in these cells remain a point of contention. We report that CAFs from skin squamous cell carcinomas (SCCs) display chromosomal alterations, with heterogeneous NOTCH1 gene amplification and overexpression that also occur, to a lesser extent, in dermal fibroblasts of apparently unaffected skin. Read More

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October 2020

Lockdown measures in response to COVID-19 in nine sub-Saharan African countries.

BMJ Glob Health 2020 10;5(10)

Institute of Population Health Sciences, Barts and London Medical and Dental School, Queen Mary University of London, London, UK

Lockdown measures have been introduced worldwide to contain the transmission of COVID-19. However, the term 'lockdown' is not well-defined. Indeed, WHO's reference to 'so-called lockdown measures' indicates the absence of a clear and universally accepted definition of the term 'lockdown'. Read More

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October 2020

Investigating the demographic history of Japan using ancient oral microbiota.

Philos Trans R Soc Lond B Biol Sci 2020 11 5;375(1812):20190578. Epub 2020 Oct 5.

Australian Centre for Ancient DNA, University of Adelaide, Adelaide, Australia.

While microbial communities in the human body (microbiota) are now commonly associated with health and disease in industrialised populations, we know very little about how these communities co-evolved and changed with humans throughout history and deep prehistory. We can now examine these communities by sequencing ancient DNA preserved within calcified dental plaque (calculus), providing insights into the origins of disease and their links to human history. Here, we examine ancient DNA preserved within dental calculus samples and their associations with two major cultural periods in Japan: the Jomon period hunter-gatherers approximately 3000 years before present (BP) and the Edo period agriculturalists 400-150 BP. Read More

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November 2020

Apical peri-prostatic nerve block versus intra-rectal xylocaine gel for trans- rectal ultrasound guided prostate biopsy among Nigerian patients: A prospective randomized study.

Niger J Clin Pract 2020 Sep;23(9):1183-1187

Department of Surgery, College of Medicine, University of Benin, Benin City, Edo State, Nigeria.

Aims: This study compared the analgesic effect of apical peri-prostatic block with that of intra-rectal xylocaine gel for trans-rectal ultrasound guided prostate biopsy (TRUS-PBx) in Nigeria.

Methods: This is a prospective randomized comparative study carried out over one year in University of Benin Teaching Hospital, Edo State, Nigeria. The participants were randomized into two groups; Group A had 10 mls of intra-rectal xylocaine gel instillation while Group B had apical infiltration of 10 mls of 1% xylocaine all before TRUS-PBx. Read More

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September 2020

Descriptive epidemiology of coronavirus disease 2019 in Nigeria, 27 February-6 June 2020.

Epidemiol Infect 2020 09 11;148:e208. Epub 2020 Sep 11.

Office of the Director General, Nigeria Centre for Disease Control, Abuja, Nigeria.

The objective of this study was to describe the epidemiology of COVID-19 in Nigeria with a view of generating evidence to enhance planning and response strategies. A national surveillance dataset between 27 February and 6 June 2020 was retrospectively analysed, with confirmatory testing for COVID-19 done by real-time polymerase chain reaction (RT-PCR). The primary outcomes were cumulative incidence (CI) and case fatality (CF). Read More

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September 2020

Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria.

Adv Hematol 2020 27;2020:2659398. Epub 2020 Aug 27.

Haematology Unit, Department of Medical Laboratory Science, University of Calabar, Calabar, Nigeria.

Background: Rhesus antigens have been documented to cause haemolytic disease of the newborn as well as acute and delayed transfusion reactions. This study was performed to evaluate the frequency of rhesus antigens (C, c, D, E, and e) in the studied population.

Method: This study was a cross-sectional study involving 130 prospective blood donors attending University of Calabar Teaching Hospital (UCTH) donor clinic. Read More

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Indoor radon exposure and excess of lung cancer mortality: the case of Mexico-an ecological study.

Environ Geochem Health 2021 Jan 24;43(1):221-234. Epub 2020 Aug 24.

SNI, Sistema Nacional de Investigadores, Mexico, Mexico.

Radon is a radioactive gas that can migrate from soils and rocks and accumulate in indoor areas such as dwellings and buildings. Many studies have shown a strong association between the exposure to radon, and its decay products, and lung cancer (LC), particularly in miners. In Mexico, according to published surveys, there is evidence of radon exposure in large groups of the population, nevertheless, only few attention has been paid to its association as a risk factor for LC. Read More

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January 2021

A conservation checklist of the amphibians and reptiles of the State of Mexico, Mexico with comparisons with adjoining states.

Zookeys 2020 27;953:137-159. Epub 2020 Jul 27.

Department of Biology, Denison University, Granville, Ohio 43023, USA Denison University Granville United States of America.

The State of Mexico has a unique combination of geographic characteristics and topography that promotes a high biodiversity. Unfortunately, continued human population growth of the metropolitan areas of Mexico City and Toluca have degraded the environment of the State of Mexico, which threatened its wildlife. An updated checklist of the amphibians and reptiles of the State of Mexico is provided and their conservation status summarized. Read More

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Frailty among middle-aged and older Canadians: population norms for the frailty index using the Canadian Longitudinal Study on Aging.

Age Ageing 2021 02;50(2):447-456

Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Background: frailty is a public health priority now that the global population is ageing at a rapid rate. A scientifically sound tool to measure frailty and generate population-based reference values is a starting point.

Objective: in this report, our objectives were to operationalize frailty as deficit accumulation using a standard frailty index (FI), describe levels of frailty in Canadians ≥45 years old and provide national normative data. Read More

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February 2021

Functional Gene Diversity of Selected Indigenous Hydrocarbon-Degrading Bacteria in Aged Crude Oil.

Int J Microbiol 2020 30;2020:2141209. Epub 2020 Jul 30.

Department of Pure and Industrial Chemistry, University of Port Harcourt, Port Harcourt, Rivers State, Nigeria.

Crude oil pollution has consistently deteriorated all environmental compartments through the cycle of activities of the oil and gas industries. However, there is a growing need to identify microbes with catabolic potentials to degrade these pollutants. This research was conducted to identify bacteria with functional degradative genes. Read More

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