20,041 results match your criteria ectopic pregnancy


A Scary Complication: Single-center Study on Management and Outcome of Cesarean Scar Pregnancy.

Rev Bras Ginecol Obstet 2021 Apr 12;43(4):311-316. Epub 2021 May 12.

Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany.

A cesarean scar pregnancy (CSP) is a scary and life-threatening complication of cesarean section (CS). Nevertheless, the incidence of CS is constantly growing. The CSP incidence is 0,15% of pregnancies after CS which represents 6,1% of all ectopic pregnancies in women with condition after CS. Read More

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Tryptophan Operon Diversity Reveals Evolutionary Trends among Geographically Disparate Chlamydia trachomatis Ocular and Urogenital Strains Affecting Tryptophan Repressor and Synthase Function.

mBio 2021 May 11;12(3). Epub 2021 May 11.

Department of Pediatrics, University of California San Francisco, Oakland, California, USA

The obligate intracellular pathogen () is the leading cause of bacterial sexually transmitted infections and blindness globally. To date, urogenital strains are considered tryptophan prototrophs, utilizing indole for tryptophan synthesis within a closed-conformation tetramer comprised of two α (TrpA)- and two β (TrpB)-subunits. In contrast, ocular strains are auxotrophs due to mutations in TrpA, relying on host tryptophan pools for survival. Read More

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Ectopic decidua of the appendix: a case report.

Surg Case Rep 2021 May 11;7(1):117. Epub 2021 May 11.

Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Background: Ectopic decidua is the presence of decidual tissue outside the uterus. Ectopic decidua of the appendix is a rare entity that can present with abdominal symptoms mimicking appendicitis. We report a case of a 39-year-old female patient at 27 weeks gestational age with a 2-day history of right lower quadrant abdominal pain. Read More

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Comparison of the Method of Endometrial Preparation Prior to Frozen-Thawed Embryo Transfer: a Retrospective Cohort Study from 9733 Cycles.

Reprod Sci 2021 May 10. Epub 2021 May 10.

Department of Gynecology, The First Affiliated Hospital of Xi'an Medical College, Xi'an City, Shaanxi Province, China.

Our objective was to compare the effectiveness of natural cycles (NC), modified natural cycle (mNC), and artificial cycles (AC) in women undergoing frozen-thawed embryo transfer (FET) after in vitro fertilization (IVF). This is a retrospective cohort study analyzing 9733 women undergoing the first cycle of FET over a 3-year period (June 2014-December 2017) at Northwest Women's and Children's Hospital after IVF-ICSI cycles. The type of endometrial preparation was determined by the treating physician's preference, based on patients' characteristics. Read More

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Live birth by cesarean section after rupture of uterine cornua in simultaneous corneal and intrauterine pregnancies.

J Obstet Gynaecol Res 2021 May 9. Epub 2021 May 9.

Department of Obstetrics and Gynecology, The Japanese Red Cross Maebashi Hospital, Maebashi, Japan.

A patient became pregnant by in vitro fertilization and embryo transfer (IVF-ET). She had a history of laparoscopic bilateral salpingectomy and enucleation of a left ovarian tumor due to bilateral hydrosalpinx and left endometriotic cyst in primary infertility. She noticed abdominal pain and visited the nearby general hospital by ambulance (gestational age 6 weeks and 1 day). Read More

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False negative point-of-care urine pregnancy tests in an urban academic emergency department: a retrospective cohort study.

J Am Coll Emerg Physicians Open 2021 Jun 1;2(3):e12427. Epub 2021 May 1.

Department of Emergency Medicine Boston Medical Center Boston University School of Medicine Boston Massachusetts USA.

Study Objective: To determine the prevalence of false negative point-of-care (POC) urine pregnancy tests among emergency department (ED) patients and among those with abdominal pain or vaginal bleeding.

Methods: We identified all female patients, ages 14-50 years without prior hysterectomy who had a negative POC urine pregnancy test (beta subunit of human chorionic gonadotropin [β-hCG]) performed by trained clinical staff in the ED between September 1, 2017 and December 31, 2018, as well as a subgroup we defined a priori as "high risk" for early pregnancy complications based on a triage chief complaint (text) of abdominal pain or vaginal bleeding. We identified those with a positive urine β-hCG, serum β-hCG >5 mIU/mL, or a diagnosis of pregnancy within 3 months of the initial ED visit (index visit). Read More

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Randomized trial of the application value of comprehensive nursing intervention in the perioperative period of ruptured bleeding of ectopic pregnancy.

Ann Palliat Med 2021 Apr;10(4):4593-4600

Department of Gynaecology and Obstetrics, Zhuji Fifth People's Hospital, Zhuji, China.

Background: The purpose of this study was to explore the value of comprehensive nursing intervention in the perioperative period of ruptured bleeding of ectopic pregnancy.

Methods: From January 2015 to January 2020, 164 patients with rupture and bleeding of ectopic pregnancy who needed laparoscopic treatment in the department of gynecology at our hospital were selected and randomly divided into the basic nursing group and the comprehensive nursing group, with 82 cases each. During the perioperative period, comprehensive nursing intervention or basic nursing intervention were performed, and the nursing effects of the two nursing interventions were compared. Read More

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You cannot ablate the Lernaean Hydra: SCN5A mutation in a patient with multifocal ectopic Purkinje-related premature contractions syndrome treated with Flecainide and an implant of a subcutaneous defibrillator-a case report.

Eur Heart J Case Rep 2021 Apr 30;5(4):ytab158. Epub 2021 Apr 30.

University Hospital of Patras, Rio, Patras, 26504, Greece.

Background: SCN5A mutations may present with different clinical phenotypes such as Brugada syndrome, long QT3 syndrome, sick sinus syndrome, atrial fibrillation, dilated cardiomyopathy, and the least known multifocal ectopic Purkinje-related premature contractions syndrome.

Case Summary: We report a case of a 29-year-old woman with palpitations due to multifocal premature ventricular complexes (PVCs) and a family history of sudden death. The previous electrophysiological study had shown that PVCs arose from Purkinje fibres but catheter ablation was unsuccessful. Read More

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Potential risk factors for caesarean scar pregnancy: a retrospective case-control study.

Hum Reprod Open 2021 1;2021(2):hoab019. Epub 2021 May 1.

Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden.

Study Question: What are the important risk factors for having a caesarean scar pregnancy (CSP)?

Summary Answer: Independent risk factors were smoking in the first trimester, higher parity, and previous caesarean section (CS) before the index caesarean delivery.

What Is Known Already: A spectrum of risk factors for CSP has been suggested but not proven: parity, number of previous caesarean section, elective as opposed to emergency CS, IVF-pregnancy, breech presentation, previous gynaecological surgery as well as suture technique.

Study Design Size Duration: This retrospective case-control study included 31 women with a CSP during the period 2003-2018 treated at a tertiary care centre for gynaecology and reproduction. Read More

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Use of the Purse-String Suture to Conservatively Manage a Cornual Ectopic Pregnancy.

Cureus 2021 Apr 1;13(4):e14249. Epub 2021 Apr 1.

Obstetrics and Gynecology, Bethesda Hospital East, Boynton Beach, USA.

We report the successful management of a 31-year-old female, treated by cornual wedge resection. The patient suffered from vaginal spotting and lower abdominal pain. Transvaginal ultrasonography revealed a 4-5 cm right cornual pregnancy and beta-human chorionic gonadotropin was measured to be 614. Read More

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The Predictive Value of Decisive and Soft Ultrasound Criteria for Ectopic Pregnancy Identification in 321 Preoperative Cases.

Ultraschall Med 2021 May 6. Epub 2021 May 6.

Department of Gynecology, University Hospital Zürich, Switzerland.

Purpose:  To define the predictive value of morphological types (MTs) and further criteria in diagnosing ectopic pregnancy (ECP) by transvaginal sonography (TVS) prior to operative confirmation and treatment.

Materials And Methods:  Retrospective cohort analysis of 321 consecutive patients with suspected ECP who were advised to undergo operation.

Results:  ECP was investigated by TVS in all 321 patients. Read More

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Tubal stump pregnancy after salpingectomy-Does the time interval from surgical intervention to conception matter?

J Obstet Gynaecol Res 2021 May 4. Epub 2021 May 4.

Department of Obstetrics and Gynecology, The Yitzhak Shamir Medical Center (formerly Assaf Harofeh Medical Center), Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Aim: Ectopic pregnancy implantation on the tubal stump after salpingectomy is a rare location for extrauterine pregnancy, whose pathogenesis is still unknown. The purpose of this study was to examine whether the time interval elapsed from salpingectomy may predispose the embryo to implantation on the tubal stump in the next pregnancy subsequent to tube removal.

Methods: Nine women operated for stump pregnancy (study group) between 2008 and 2019 were retrospectively identified. Read More

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A life-threatening condition - ruptured ectopic pregnancy with negative urine pregnancy test: A case report.

Malays Fam Physician 2021 Mar 1;16(1):121-123. Epub 2021 Feb 1.

MD (UPM), MMed Family Medicine (UPM), Department of Family Medicine, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia.

Ectopic pregnancy is an extra-uterine pregnancy and is a potentially life-threatening condition that can lead to death from intra-peritoneal hemorrhage. This case reports a rare occurrence of ruptured tubal pregnancy in which the patient presented early with abdominal pain and a negative urine pregnancy test but subsequently presented again with evidence of intra-peritoneal hemorrhage. A negative urine pregnancy test is often used to rule out pregnancy, but it is not 100% sensitive. Read More

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Single-dose administration of a short-acting gonadotropin-releasing hormone agonist does not affect cycle outcome in frozen-thawed embryo transfer cycles.

J Int Med Res 2021 May;49(5):3000605211012247

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

Objective: This prospective study aimed to assess the effect of short-acting gonadotropin-releasing hormone agonist (GnRHa) administration on pregnancy outcomes in frozen-thawed embryo transfer (FET) cycles.

Methods: Patients who planned to have FET in Peking Union Medical College Hospital (China) were recruited for this study and randomly assigned into two groups. Patients in the experimental group (n = 460) received triptorelin acetate on the day of embryo transfer along with routine luteal support. Read More

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A ruptured seventeen weeks' ectopic pregnancy: A case report.

J Pak Med Assoc 2021 Feb;71(2(B)):763-765

Department of North Surgery, King Edward Medical University, Mayo Hospital Lahore, Lahore, Pakistan.

Ectopic pregnancy is a common condition with a prevalence of 2% in all pregnancies. Implantation of the developing blastocyst outside the uterine cavity leads to ectopic pregnancy. About 95% of ectopic pregnancies occur in the different segments of the fallopian tubes. Read More

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February 2021

Deaths and Severe Adverse Events after the use of Mifepristone as an Abortifacient from September 2000 to February 2019.

Issues Law Med 2021 ;36(1):3-26

Associate Professor of Family Medicine, Liberty University College of Osteopathic Medicine.

Objectives: Primary: Analyze the Adverse Events (AEs) reported to the Food and Drug Administration (FDA) after use of mifepristone as an abortifacient. Secondary: Analyze maternal intent after ongoing pregnancy and investigate hemorrhage after mifepristone alone.

Methods: Adverse Event Reports (AERs) for mifepristone used as an abortifacient, submitted to the FDA from September 2000 to February 2019, were analyzed using the National Cancer Institute's Common Terminology Criteria for Adverse Events (CTCAEv3). Read More

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January 2021

Embryonic exposure to hyper glucocorticoids suppresses brown fat development and thermogenesis via REDD1.

Sci Bull (Beijing) 2021 Mar 28;66(5):478-489. Epub 2020 Oct 28.

Nutrigenomics and Growth Biology Laboratory, Department of Animal Sciences, Washington State University, Pullman, WA 99164, USA.

Maternal stress during pregnancy is prevailing worldwide, which exposes fetuses to intrauterine hyper glucocorticoids (GC), programming offspring to obesity and metabolic diseases. Despite the importance of brown adipose tissue (BAT) in maintaining long-term metabolic health, impacts of prenatal hyper GC on postnatal BAT thermogenesis and underlying regulations remain poorly defined. Pregnant mice were administrated with synthetic GC dexamethasone (DEX) at levels comparable to fetal GC exposure of stressed mothers. Read More

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Persistent increase of β-hCG level after salpingectomy in tubal pregnancy: Good or bad news?

Clin Case Rep 2021 Apr 11;9(4):2369-2372. Epub 2021 Mar 11.

Department of Obstetrics and Gynecology LMU Munich Munich Germany.

Heterotopic pregnancy is a rare event in natural conception (1:30000). We describe a case of a 36-year-old nulliparous. She presented to our department in the 4 + 6 gestational week with two simultaneous pregnancies intrauterine and extrauterine. Read More

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Placenta accreta after postpartum tubal sterilisation and Novasure endometrial ablation.

Clin Case Rep 2021 Apr 27;9(4):2125-2128. Epub 2021 Feb 27.

Watford General Hospital Watford UK.

Although rare, pregnancy can still occur after both tubal sterilization and endometrial ablation. The resulting pregnancy is often complicated by ectopic pregnancy, miscarriage, and adherent placenta. Endometrial ablation is not a contraceptive. Read More

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Caesarean scar ectopic pregnancy: a case series and case report to highlight the experience in regional New Zealand.

N Z Med J 2021 04 16;134(1533):61-70. Epub 2021 Apr 16.

Obstetrician and Gynaecologist, Palmerston North Hospital, Midcentral District Health Board, Palmerston North.

Aims: To evaluate the approach to diagnosis and management of caesarean scar pregnancy (CSP) at a regional New Zealand hospital.

Methods: A retrospective case series of ten patients between June 2015 and May 2020. The data review included demographic information, ultrasound findings, human chorionic gonadotropin (HCG) levels, primary and subsequent treatment, outcomes and complications. Read More

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Cesarean Scar Pregnancy Treated by Artery Embolization Combined with Diode Laser: A Novel Approach for a Rare Disease.

Medicina (Kaunas) 2021 Apr 23;57(5). Epub 2021 Apr 23.

Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynaecology, University of Foggia, 71121 Foggia, Italy.

Cesarean scar pregnancy (CSP) is a rare form of ectopic pregnancy which represents a consequence of a previous cesarean section. It is associated with major maternal morbidity and mortality and has potential implications on future fertility. Because of possible serious complications, CSP should be swiftly diagnosed and treated. Read More

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Cesarean Scar Ectopic Pregnancy-Case Series: Treatment Decision Algorithm and Success with Medical Treatment.

Medicina (Kaunas) 2021 Apr 8;57(4). Epub 2021 Apr 8.

FEA Obstetric and Gynecology Hospital Regional Materno Infantil, C.P.29011 Málaga, Spain.

: Cesarean scar ectopic pregnancies are a rare form of extrauterine pregnancies, yet their incidence has increased along with the rise in the number of cesarean deliveries. As with other ectopic pregnancies, cesarean scar ectopic pregnancies pose a greater risk for maternal hemorrhage and ultimately maternal mortality. : We present a series of clinical cases of cesarean scar ectopic pregnancy diagnosed by transvaginal ultrasonography. Read More

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Development and evaluation of a Point-of-Care Test (POCT) in a low resource setting with high rates of urogenital infections in Fiji.

J Clin Microbiol 2021 Apr 28. Epub 2021 Apr 28.

Lucira Health, Emeryville, CA, USA

Rapid and precise detection of -the leading global cause of sexually transmitted infections (STI)-at the point-of-care (POC) is required for treatment decisions to prevent transmission and sequelae including pelvic inflammatory disease, ectopic pregnancy, tubal-factor infertility and preterm birth. We developed a rapid POC test (POCT), termed LH-POCT, which uses Loop-mediated AMPlification (LAMP) of nucleic acids, and performed a head-to-head comparison with the Cepheid Xpert® CT/NG assay using clinician-collected de-identified paired vaginal samples from a parent study that consecutively enrolled symptomatic and asymptomatic females over age 18 years from the Ministry of Health and Medical Services Health Centers in Fiji. Samples were processed by the Xpert® CT/NG assay and LH-POCT, blinded to the comparator. Read More

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Point-of-Care Ultrasound Facilitates Management of Ruptured Ectopic Pregnancy.

Pediatr Emerg Care 2021 May;37(5):282-285

Emergency Medicine, Medical University of South Carolina, Charleston, SC.

Abstract: Abdominal pain in the pregnant adolescent presents a diagnostic dilemma with potential life-threatening etiologies. We present a case where point-of-care ultrasound was used to facilitate diagnosis and expedite lifesaving management of a ruptured ectopic pregnancy. We further review the technique and literature for first-trimester transabdominal point-of-care ultrasound. Read More

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Ectopic pregnancies and endometrial microbiota.

Curr Opin Obstet Gynecol 2021 Jun;33(3):202-206

Hospital La Paz, Madrid, Spain.

Purpose Of The Review: In recent years there has been significant progress in the study of endometrial microbiota. This line of investigation has not been free of controversy and discussion. It is a key for clinicians involved to remain updated with the most recent findings in microbiome and its clinical implications to be able to offer patients all possible treatments. Read More

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Association of complicated appendicitis on the risk of later in vitro fertilization treatment requirement and ectopic pregnancy: a nationwide cohort study.

Acta Obstet Gynecol Scand 2021 Apr 24. Epub 2021 Apr 24.

Department of Gastrointestinal Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Introduction: A Population-based register study utilizing three Finnish National Registers was carried out to determine whether uncomplicated appendicitis, complicated appendicitis, and appendectomy without appendicitis are associated with a subsequent risk of requiring in vitro fertilization (IVF) treatment or a risk of ectopic pregnancy among reproductive-aged women.

Material And Methods: A total of 23 997 women who underwent appendectomy for uncomplicated or complicated appendicitis or for nonspecific abdominal pain or had nonspecific abdominal pain without surgical procedures between 2000 and 2012 were included in the study. The later IVF treatment requirement and ectopic pregnancy risk were assessed after uncomplicated appendicitis, complicated appendicitis, and appendectomy without appendicitis. Read More

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Efficient application of the "Hand As Foot" teaching method in the clinical teaching of ectopic pregnancy.

Asian J Surg 2021 Apr 21. Epub 2021 Apr 21.

Inner Mongolia Medical University, Department of Obstetrics and Gynecology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot North Street, Inner Mongolia 010050, China.

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Laparoscopic management of a primary posterior cul-de-sac abdominal ectopic pregnancy.

Fertil Steril 2021 Apr 20. Epub 2021 Apr 20.

Department of Obstetrics and Gynecology, New York Presbyterian Hospital-Weill Cornell Medicine, New York, New York. Electronic address:

Objective: To report a case of laparoscopic management of a primary posterior cul-de-sac abdominal ectopic pregnancy (AEP).

Design: Video article.

Setting: Academic medical center. Read More

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Mid-trimester cesarean scar pregnancy: a case report.

Fertil Res Pract 2021 Apr 23;7(1):10. Epub 2021 Apr 23.

Division of Reproductive Endocrinology and Infertility (REI), Massachusetts General Hospital, Yawkey Center - 10th Floor, Boston, MA, 02114, USA.

Background: This article reports a unique case of cesarean scar pregnancy, demonstrating importance of early management and diagnosis.

Case Presentation: A 30-year-old pregnant woman with prior history of two cesarean sections found to have cesarean scar pregnancy at approximately 13 weeks' gestation and underwent a gravid hysterectomy.

Conclusions: While rare, cesarean scar pregnancies should be considered on the differential diagnosis of any pregnant patient with history of cesarean section who presents in early pregnancy with vaginal bleeding and/or cramping. Read More

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