17,659 results match your criteria ectasia


Clinical outcome of patients with ST-elevation myocardial infarction and angiographic evidence of coronary artery ectasia.

Catheter Cardiovasc Interv 2021 May 5. Epub 2021 May 5.

Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi (Salerno), Italy.

Objectives: The aim of this study was to describe the prevalence of coronary artery ectasia (CAE) in patients with ST-elevation myocardial infarction (STEMI) and to compare the long-term outcome of subjects with and without CAE undergoing emergent coronary angiography.

Background: The prognostic impact of CAE in STEMI patients has been poorly investigated.

Methods: This retrospective, single-center, study included consecutive patients with STEMI undergoing emergent coronary angiography from January 2012 to December 2017. Read More

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Comparison of changes in corneal volume and corneal thickness after myopia correction between LASIK and SMILE.

PLoS One 2021 4;16(5):e0250700. Epub 2021 May 4.

Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.

Myopia is the most common refractive error. Surgical correction with laser is possible. LASIK and SMILE are the techniques currently most used. Read More

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Intracranial dolichoectasia in patients with symptomatic intracranial atherosclerotic disease: Results from the MYRIAD study.

J Neuroimaging 2021 May 4. Epub 2021 May 4.

Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA.

Background And Purpose: It is unknown whether intracranial atherosclerotic disease (ICAD), in addition to causing stenosis, also associates with abnormal arterial enlargement, a condition known as intracranial dolichoectasia (IDE). Across symptomatic ICAD patients, we aim to determine IDE prevalence and IDE impact on cerebral hemodynamics and recurrent cerebral ischemia.

Methods: We analyzed 98 participants (mean age 63. Read More

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Irregular Astigmatism Management Using SPOT Scleral Lenses in the Treatment of Corneal Ectasia and Penetrating Keratoplasty.

Eye Contact Lens 2021 Apr 26. Epub 2021 Apr 26.

University Hospital of Clermont-Ferrand (V.N., J.-V.B., R.J., A.C., F.C.), CHU Clermont-Ferrand, Ophthalmology, Clermont-Ferrand, France; Université Clermont Auvergne (V.N., F.C.), CNRS UMR 6293, INSERM U1103, Genetic Reproduction and Development Laboratory (GReD), Translational Approach to Epithelial Injury and Repair Team, Clermont-Ferrand, France; The University of Sydney (S.L.W.), Save Sight Institute, Discipline of Ophthalmology, Faculty of Medicine and Health, Sydney, Australia; Sydney Eye Hospital (S.L.W.), Sydney, Australia; University Hospital of Clermont Ferrand (C.L.), CHU Clermont-Ferrand, Clinical Research and Innovation Direction, Clermont-Ferrand, France; and Université Clermont Auvergne (F.D.), CNRS, LaPSCo, Physiological and Psychosocial Stress, CHU Clermont-Ferrand, University Hospital of Clermont-Ferrand, Preventive and Occupational Medicine, Witty Fit, Clermont-Ferrand, France.

Purpose: To evaluate the outcome of SPOT scleral lenses in the management of irregular astigmatism in patients with corneal ectasia and penetrating keratoplasty. Second, we analyzed patients' characteristics and tolerance, comfort, and geometries of fitted lenses.

Method: Over a 5-year period, we included patients experiencing irregular astigmatism fitted with SPOT scleral contact lenses, from the University Hospital of Clermont-Ferrand, France. Read More

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Corneal biomechanical changes in allergic conjunctivitis.

Eye Vis (Lond) 2021 May 3;8(1):17. Epub 2021 May 3.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, Guangdong, China.

Background: To explore corneal biomechanical changes, identify related factors and determine early indicators of keratoconus (KC) development risk in allergic conjunctivitis (AC) patients.

Methods: A total of 50 patients, including 20 eyes without AC and 30 eyes with AC were enrolled in this study. All patients underwent a complete ocular examination, including evaluations of clinical manifestations of AC, corneal tomography and densitometry by Pentacam, corneal biomechanics by Corvis ST, and corneal and epithelial thickness mapping by RTvue optical coherence tomography (OCT). Read More

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Anti-RNA Polymerase III Antibodies in Systemic Sclerosis: Multicentric Study from Argentina.

Reumatol Clin 2021 Apr 28. Epub 2021 Apr 28.

Servicio de Inmunología, Instituto de Investigaciones Médicas «Dr. Alfredo Lanari», UBA, Ciudad Autónoma de Buenos Aires, Argentina.

Objective: To describe the frequency of anti-RNA polymerase III antibody in patients with Systemic Sclerosis (SSc) of a group of healthcare centres from Argentina and to explore differences among patients with positive and negative anti-RNA polymerase III antibody.

Patients And Methods: Data from clinical records, anamnesis and physical examination were collected from 135 patients with SSc (ACR/EULAR 2013). A serum sample from each patient was obtained for the detection of anti-RNA polymerase III IgG antibodies by ELISA. Read More

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Liver histopathology in COVID-19 patients: A mono-Institutional series of liver biopsies and autopsy specimens.

Pathol Res Pract 2021 Apr 19;221:153451. Epub 2021 Apr 19.

Department of Medicine (DIMED), University of Padua, Padua, Italy.

Few studies have focused on COVID-19 patients' hepatic histopathological features. Many of the described morphological landscapes are non-specific and possibly due to other comorbidities or to Sars-CoV-2-related therapies. We describe the hepatic histopathological findings of 3 liver biopsies obtained from living COVID-19 patients in which active SARS-CoV-2 infection was molecularly confirmed and biopsied because of significant alterations of liver function tests and 25 livers analyzed during COVID-19-related autopsies. Read More

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Long term results of accelerated 9 mW corneal crosslinking for early progressive keratoconus: the Siena Eye-Cross Study 2.

Eye Vis (Lond) 2021 May 1;8(1):16. Epub 2021 May 1.

Departmental Ophthalmology Unit, USL Toscana Sud-Est, Campostaggia, Siena, Italy.

Purpose: To assess clinical results of the 9 mW/5.4 J/cm accelerated crosslinking (ACXL) in the treatment of progressive keratoconus (KC) over a span of 5 years.

Methods: The prospective open non-randomized interventional study (Siena Eye-Cross Study 2) included 156 eyes of 112 patients with early progressive KC undergoing the Epi-Off 9 mW/5. Read More

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Prevalence and risk factors for keratoconus in a university-based population in Turkey.

J Cataract Refract Surg 2021 Apr 5. Epub 2021 Apr 5.

Devrek State Hospital, Department of Ophthalmology, Zonguldak, Turkey Eskişehir Osmangazi University Medical School, Department of Ophthalmology, Eskişehir, Turkey.

Purpose: This study aimed to determine the prevalence of keratoconus (KC) in the students and faculty members (aged ≥18 and ≤30 years) studying/working at the Medical and Health Sciences faculties of Eskişehir Osmangazi University.

Setting: Eskişehir Osmangazi University.

Design: Prevalence study. Read More

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Alternative Indications for Corneal Crosslinking.

J Cataract Refract Surg 2021 Apr 5. Epub 2021 Apr 5.

University Hospitals Leuven Department of Ophthalmology Leuven, Belgium KU Leuven, Biomedical Sciences Group Department of Neurosciences, Research group Ophthalmology Leuven, Belgium VITO (Flemish Institute for Technological Research) Health Unit Mol, Belgium.

Abstract: Corneal crosslinking (CXL) is the current mainstay treatment for progressive keratoconus. In the past 15 years, a variety of other indications have been tested. A systematic review was conducted to examine these alternative indications for CXL. Read More

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Mucocele-like Lesion of the Breast Diagnosed on Core Biopsy: Histologic and Clinical Analysis of 78 Cases With Focus on Features Associated With Upgrade.

Arch Pathol Lab Med 2021 Apr 30. Epub 2021 Apr 30.

From the Department of Pathology and Laboratory Medicine (Towne, Ginter), Weill Cornell Medicine, New York, New York.

Context.—: Mucocele-like lesion of the breast (MLL) is an uncommon entity, and recent studies show low rates of upgrade from core needle biopsy (CNB) to excision.

Objective. Read More

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Congenital segmental dilatation of the jejunum in an African child: a case report.

Pan Afr Med J 2021 3;38:122. Epub 2021 Feb 3.

Department of Surgery, University Clinics of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.

Congenital segmental dilatation of the intestine is a rare disease. It is rarely located in the jejunum and its etiology is still unknown despite many theories suggesting its mechanism. We report a case of a 17 months girl who experienced nonspecific symptoms (abdominal pain, constipation and loss of appetite) since early her infancy. Read More

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Prevalence of Thoracic Aortic Aneurysms in Patients with Degenerative Abdominal Aortic Aneurysms: Results from the Prospective ACTA Study.

Eur J Vasc Endovasc Surg 2021 Apr 20. Epub 2021 Apr 20.

Department of Vascular Surgery, APHM, Timone Hospital, Marseille, France; Aortic Centre, APHM, Timone Hospital, Marseille, France. Electronic address:

Objective: There are no recommendations for screening for thoracic aortic aneurysms (TAAs), even in patients with infrarenal abdominal aortic aneurysms (AAAs). The aims of this study were to determine the prevalence of TAAs in patients with AAAs and to analyse the risk factors for this association.

Methods: This was a multicentre prospective study. Read More

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Postoperative corneal biomechanics and influencing factors during femtosecond-assisted laser in situ keratomileusis (FS-LASIK) and laser-assisted subepithelial keratomileusis (LASEK) for high myopia.

Lasers Med Sci 2021 Apr 23. Epub 2021 Apr 23.

Eye Hospital of Shandong First Medical University, 372 Jingsi Road, Jinan, 250021, China.

The purpose of this study is to compare the postoperative corneal biomechanics and assess the influence factors after femtosecond-assisted laser in situ keratomileusis (FS-LASIK) and laser-assisted subepithelial keratomileusis (LASEK) for high myopia. In this retrospective study, patients who completed 1-year follow-up were included. The corneal biomechanical parameters, including deformation amplitude ratio 2. Read More

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Revisiting the Robustness of Pentacam HR Indices Against Soft Contact Lens Wear.

Clin Ophthalmol 2021 15;15:1573-1581. Epub 2021 Apr 15.

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Purpose: To evaluate various selected Pentacam HR indices in a cohort of soft contact lens (SCL) wearers before and after SCL discontinuation.

Methods: Ninety right eyes of 90 SCL wearers (group 1) were compared to healthy controls (group 2). For group 1 eyes, Pentacam HR images were captured within one hour of SCL removal and after one month of discontinuation. Read More

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Clinical implications of arterial hypertension in patients with spontaneous coronary artery dissection.

Coron Artery Dis 2021 Apr 19. Epub 2021 Apr 19.

Cardiac Department, Hospital Universitario de La Princesa, IIS-IP, Universidad Autónoma de Madrid, CIBERCV, Madrid Cardiac Department, Hospital del Mar - Parc de Salut Mar Grupo de Investigación Biomédica en Enfermedades del Corazón, IMIM, Barcelona Cardiac Department, Hospital General Universitario Gregorio Marañón, IIS-GM, CIBERCV, Madrid Cardiac Department, Hospital Universitari de Bellvitge, L´Hospitalet de Llobregat, Barcelona Cardiac Deprtament, Hospital Clínico Universitario de Valladolid, ICICOR Cardiac Department, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona Cardiac Department, Complexo Hospitalario Universitario de A Coruña, A Coruña Cardiac Department, Hospital Clinic de Barcelona, Barcelona Cardiac Department, Complejo Asistencial Universitario de León Cardiac Department, Hospital Miguel Servet Zaragoza Cardiac Department, Hospital General Universitario de Ciudad Real Cardiac Department, Hospital Clinico de Valencia Cardiac Department, Hospital Universitario de Albacete, Albacete, Spain.

Background: Spontaneous coronary artery dissection (SCAD) is a rare but increasingly recognized cause of acute coronary syndrome. Many patients with SCAD have associated coronary risk factors. However, the implications of arterial hypertension in SCAD patients remain unknown. Read More

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The efficiency and safety of oxygen-supplemented accelerated transepithelial corneal cross-linking.

Int Ophthalmol 2021 Apr 19. Epub 2021 Apr 19.

Department of Ophthalmology, Recep Tayyip Erdogan University Medical Faculty, Rize, Turkey.

Purpose: To investigate the impact of oxygen delivery on the clinical outcomes of accelerated transepithelial corneal cross-linking (A-TE CXL).

Methods: Fifty-seven eyes of 44 progressive keratoconus (KCN) patients were randomly separated into two age-sex-matched groups. Twenty-nine eyes of 23 KCN patients that underwent oxygen-supplemented A-TE CXL formed the study group and 28 eyes of 21 patients treated with the same procedure but under room air conditions formed the control group. Read More

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Severe congenital cutis laxa: Identification of novel homozygous LOX gene variants in two families.

Clin Genet 2021 Apr 18. Epub 2021 Apr 18.

Genetic Services of Western Australia, King Edward Memorial Hospital, Perth, Western Australia, Australia.

We report three babies from two families with a severe lethal form of congenital cutis laxa. All three had redundant and doughy-textured skin and two siblings from one family had facial dysmorphism. Echocardiograms showed thickened and poorly contractile hearts, arterial dilatation and tortuosity. Read More

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The importance of heart and brain imaging in children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C).

Rheumatol Int 2021 06 17;41(6):1037-1044. Epub 2021 Apr 17.

Department of Pediatrics, Metropolitan Hospital, Piraeus, Greece.

Multisystem Inflammatory Syndrome in Children (MIS-C) recently reported in a minority of children affected by SARS-CoV-2, mimics Kawasaki disease (KD), a medium vessel vasculitis of unknown cause. In contrast to acute COVID-19 infection, which is usually mild in children, 68% of patients with MIS-C will need intensive care unit. Myocarditis and coronary artery ectasia/aneurysm are included between the main cardiovascular complications in MIS-C. Read More

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Densitometry marks delineating the affected area in keratoconus: clinical suitability of a new descriptive system based on its repeatability and reproducibility.

Ophthalmic Physiol Opt 2021 Apr 16. Epub 2021 Apr 16.

Department of Ophthalmology, Antwerp University Hospital (UZA), Edegem, Belgium.

Purpose: To present a descriptive system for the elliptic demarcation area seen in keratoconus densitometry maps (obtained with a Scheimpflug tomographer) and to evaluate its suitability for clinical practice.

Methods: The subjects were 30 keratoconus patients at different stages and 20 healthy subjects. The averaged densitometry maps ('two-layers' scan, with fixed layers 120 µm and endothelium) were analysed using a system of four categories (termed 'Brightness', 'Contrast', 'Decentration' and 'Octants surrounded by a dark line') that we created to characterise the demarcation area. Read More

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Clinical usefulness of combination therapy with polidocanol injection and argon plasma coagulation for gastric antral vascular ectasia.

JGH Open 2021 Apr 6;5(4):465-469. Epub 2021 Mar 6.

Department of Gastroenterology and Metabolism Hiroshima University Hospital Hiroshima Japan.

Background And Aim: Gastric antral vascular ectasia (GAVE) causes gastrointestinal bleeding. The initial treatment for GAVE bleeding is endoscopic hemostasis, and currently, the most performed technique to achieve hemostasis is argon plasma coagulation (APC). However, APC is associated with a high recurrence rate. Read More

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Corneal Biomechanical Assessment with Ultra-High-Speed Scheimpflug Imaging During Non-Contact Tonometry: A Prospective Review.

Clin Ophthalmol 2021 6;15:1409-1423. Epub 2021 Apr 6.

Ophthalmology Department, Centro Hospitalar Universitário do Porto, Porto, Portugal.

Background: In recent years, increasing interest has arisen in the application of data from corneal biomechanics in many areas of ophthalmology, particularly to assist in the detection of early corneal ectasia or ectasia susceptibility, to predict corneal response to surgical or therapeutic interventions and in glaucoma management. Technology has evolved and, recently, the Scheimpflug principle was associated with a non-contact air-puff tonometer, allowing a thorough analysis of corneal biomechanics and a biomechanically corrected intraocular pressure assessment, opening up new perspectives both in ophthalmology and in other medical areas. Data from corneal biomechanics assessment are being integrated in artificial intelligence models in order to increase its value in clinical practice. Read More

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Unusual pediatric epidural arteriovenous fistula with venous ectasia presented with spontaneous spinal epidural hematoma: Case report.

Interv Neuroradiol 2021 Apr 13:15910199211009121. Epub 2021 Apr 13.

Department of Neuroendovascular Therapy, St. Luke's International Hospital, Tokyo, Japan.

Background: Spontaneous spinal epidural hematoma (SSEH) is rare in children. Vascular malformation including arteriovenous fistulas and venous malformation is a rare cause of SSEH.

Case Description: A 5-year-old girl presented with 2 episodes of SSEH at the upper thoracic spine and non-hemorrhagic episodes with spontaneous neurological recovery. Read More

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Autoimmune reactivity is present in patients with incident coronary artery ectasia.

Coron Artery Dis 2021 Mar 16. Epub 2021 Mar 16.

University Cardiology Department Laboratory of Microbiology, School of Medicine, Democritus University of Thrace Cardiology Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece.

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Outcomes of Conductive Keratoplasty Combined with Corneal Crosslinking in Advanced Ectatic Corneal Disease.

Clin Ophthalmol 2021 29;15:1317-1329. Epub 2021 Mar 29.

Department of Ophthalmology, University of Arizona, Tucson, AZ, USA.

Purpose: To assess the effectiveness of a novel treatment for patients with advanced corneal ectasia and loss of visual acuity (VA). Conductive keratoplasty (CK) is performed to improve VA followed by epithelium-on (epi-on) corneal crosslinking (CXL) to stabilize the cornea after CK.

Methods: Retrospective, exploratory cohort study. Read More

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Ultrasound aspects of symptomatic versus asymptomatic forms of male accessory gland inflammation.

Andrology 2021 Apr 5. Epub 2021 Apr 5.

Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

Background: The ultrasound (US) evaluation of the Male Sex Accessory Gland Inflammation (MAGI) helps the clinicians to understand the severity of this condition, allowing them to distinguish the uncomplicated form (prostatitis) from the complicated ones (prostate-vesiculitis and prostate-vesiculitis-epididymitis), as well as the unilateral from the bilateral forms, the fibrosclerotic and the hypertrophic-congestive form.

Objective: This retrospective study aimed to evaluate the US features of MAGI patients with active symptoms compared to patients without sexual, voiding, and ejaculatory dysfunction.

Materials/methods: To achieve this aim, an analysis of the prevalence of MAGI US criteria was carried out on a very large series of over 500 patients diagnosed with MAGI classified according to the different symptom profile evaluated through a dedicated questionnaire (previously conceived and published by our group) arbitrarily named "structured interview about MAGI" (SI-MAGI) for sexual, voiding, and ejaculatory disorders reported by these patients. Read More

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Superficial Temporal Muscle Fascia Grafting: Successful Transplant of Surgical-induced Necrotizing Scleritis.

Middle East Afr J Ophthalmol 2020 Oct-Dec;27(4):238-240. Epub 2021 Jan 19.

Institute Hedi Raies of Ophthalmology, Tunis, Tunisia.

To report the case of a surgical-induced necrotizing scleritis (SINS) following vitreoretinal surgery for rhegmatogenous retinal detachment, successfully managed by superficial muscle temporal fascia grafting. An 18-year-old teenager, with a history of a 23G vitrectomy with silicone oil tamponade for rhegmatogenous retinal detachment of the left eye, presented with intense left ocular pain, decreased visual acuity to counting fingers and eye redness. Split lamp examination showed: Conjunctival infiltration with silicone oil, circumferential sclera thinning with ectasia of the underling uvea. Read More

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January 2021

Development, validation, and comparison of a nomogram based on radiologic findings for predicting malignancy in intraductal papillary mucinous neoplasms of the pancreas: An international multicenter study.

J Hepatobiliary Pancreat Sci 2021 Apr 2. Epub 2021 Apr 2.

Department of Surgery, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Background: Although we previously proposed a nomogram to predict malignancy in intraductal papillary mucinous neoplasms (IPMN) and validated it in an external cohort, its application is challenging without data on tumor markers. Moreover, existing nomograms have not been compared. This study aimed to develop a nomogram based on radiologic findings and to compare its performance with previously proposed American and Korean/Japanese nomograms. Read More

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Chemically-Boosted Corneal Cross-Linking for the Treatment of Keratoconus through a Riboflavin 0.25% Optimized Solution with High Superoxide Anion Release.

J Clin Med 2021 Mar 23;10(6). Epub 2021 Mar 23.

Unit of Ophthalmology, Department of Biomedical Sciences, Dentistry, Morphological and Functional Imaging, University of Messina, 98100 Messina, Italy.

The purpose of this study was to evaluate the effectiveness and safety of a novel buffered riboflavin solution approved for corneal cross-linking (CXL) in progressive keratoconus and secondary corneal ectasia. Following the in vivo preclinical study performed on New Zealand rabbits comparing the novel 0.25% riboflavin solution (Safecross) containing 1% hydroxypropyl methylcellulose (HPMC) with a 0. Read More

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