9,324 results match your criteria ecmo support

Paracorporeal Support in Pediatric Patients: The Role of the Patient-Device Interaction.

Ann Thorac Surg 2021 Jul 28. Epub 2021 Jul 28.

Department of Pediatric Cardiology University of Alberta, Edmonton AB, Canada; Division of Pediatric Cardiology, Stollery Children's Hospital, Edmonton AB, Canada. Electronic address:

Background: Ventricular assist devices (VADs) are important in the treatment of pediatric heart failure. While paracorporeal pulsatile (PP) devices have historically been used, there has been increased use of paracorporeal continuous (PC) devices. We sought to compare the outcomes of children supported with a PP, PC, or combination of devices. Read More

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Bilateral lung transplantation during pregnancy after ECMO for influenza-A caused ARDS.

Am J Transplant 2021 Jul 31. Epub 2021 Jul 31.

Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria.

Pregnant women with influenza-A have an increased risk of developing acute respiratory distress syndrome (ARDS). Extracorporeal membrane oxygenation (ECMO) can be used as salvage therapy, with lung transplantation as a therapeutic option. However, successful bilateral lung transplantation during pregnancy has never been reported before. Read More

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Favorable outcomes after heart transplantation in Barth syndrome.

J Heart Lung Transplant 2021 Jul 10. Epub 2021 Jul 10.

Departments of Pediatrics and Clinical and Translational Science, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address:

Background: Barth Syndrome (BTHS) is a rare, X-linked disease characterized by cardioskeletal myopathy and neutropenia. Comparative outcomes after heart transplantation have not been reported.

Methods: We identified BTHS recipients across 3 registries (Pediatric Heart Transplant Study Registry [PHTS], Barth Syndrome Research Registry and Repository, and Scientific Registry of Transplant Recipient-Pediatric Health Information System) and matched them 1:4 to non-BTHS, male heart transplant (HT) recipients listed with dilated cardiomyopathy in PHTS. Read More

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Long-Term Outcome After Venoarterial Extracorporeal Membrane Oxygenation as Bridge to Left Ventricular Assist Device Preceding Heart Transplantation.

J Cardiothorac Vasc Anesth 2021 Jul 3. Epub 2021 Jul 3.

Department of Cardiac Surgery, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.

Objectives: To determine if venoarterial extracorporeal membrane oxygenation (VA ECMO) as a bridge to left ventricular assist device (LVAD) in heart transplant (HT) candidates (ie, double bridge to HT) was associated with increased morbidity and mortality when compared to LVAD bridging to HT (ie, single bridge to HT).

Design: A retrospective analysis of patients undergoing LVAD support from 2011 to 2020. A Kaplan-Meier survival curve and Cox-Mantel hazard ratios (HR) were calculated during LVAD support and after HT. Read More

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Utilization of ECMO in vascular surgery: A presentation of two cases.

Int J Surg Case Rep 2021 Jun 29;85:106141. Epub 2021 Jun 29.

Department of Surgery, Division of Vascular Surgery, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

Introduction: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a form of temporary mechanical circulatory support commonly used during cardiothoracic interventions. Malperfusion during complex vascular procedures remains a significant risk that may potentially lead to multiple complications. Here, we report two cases highlighting the efficacy of VA-ECMO in both planned and emergent vascular interventions. Read More

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Cardiac Catheterization During Extracorporeal Membrane Oxygenation After Congenital Cardiac Surgery: A Multi-Center Retrospective Study.

Pediatr Cardiol 2021 Jul 30. Epub 2021 Jul 30.

Paediatric Cardiology Division, Department of Paediatrics, King Abdulaziz University Hospital, P.O.BOX: 80215, Jeddah, 21589, Saudi Arabia.

Cardiac catheterization can affect clinical outcomes in patients on extracorporeal membrane oxygenation (ECMO) after congenital heart surgery; however, its effect in this group of patients remains unclear. This study aimed to evaluate the safety and outcome of cardiac catheterization in patients undergoing ECMO after congenital cardiac surgery and determine predictors that influence successful weaning. This retrospective cohort study included pediatric patients who underwent cardiac catheterization while on ECMO after congenital heart surgery in two cardiac centers between November 2012 and February 2020. Read More

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Postcardiotomy Extracorporeal Membrane Oxygenation in Neonates.

Thorac Cardiovasc Surg 2021 Dec 29;69(S 03):e41-e47. Epub 2021 Jul 29.

Department of Pediatric Thoracic and Cardiovascular Surgery, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Background:  Extracorporeal membrane oxygenation (ECMO) provides circulatory support in children with congenital heart disease, particularly in the setting of cardiopulmonary failure and inability to wean from cardiopulmonary bypass. This study summarized the clinical application of ECMO in the treatment of heart failure after cardiac surgery in neonates.

Materials And Methods:  Clinical data of 23 neonates who received ECMO support in our center from January 2017 to June 2019 were retrospectively analyzed. Read More

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December 2021

Pulmonary-to-Systemic Arterial Shunt to Treat Children With Severe Pulmonary Hypertension.

J Am Coll Cardiol 2021 Aug;78(5):468-477

Congenital and Pediatric Cardiology Unit, Hospital Necker-Enfants Malades, APHP, Universitaire de Paris, Paris, France.

Background: The placement of a pulmonary-to-systemic arterial shunt in children with severe pulmonary hypertension (PH) has been demonstrated, in relatively small studies, to be an effective palliation for their disease.

Objectives: The aim of this study was to expand upon these earlier findings using an international registry for children with PH who have undergone a shunt procedure.

Methods: Retrospective data were obtained from 110 children with PH who underwent a shunt procedure collected from 13 institutions in Europe and the United States. Read More

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A Narrative Review of Nutrition Therapy in Patients Receiving Extracorporeal Membrane Oxygenation.

Terpsi Karpasiti

ASAIO J 2021 Jul 27. Epub 2021 Jul 27.

From the Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom Barts Health NHS Trust, St Bartholomew's Hospital, West Smithfield, London, United Kingdom.

The use of extracorporeal membrane oxygenation (ECMO) in patients with severe cardiorespiratory failure has seen significant growth in the last decade. Despite this, there is paucity of data surrounding the optimum nutritional management for ECMO patients. This review aimed to describe current nutrition practices in patients receiving ECMO, critically appraise available studies and identify areas for future research. Read More

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Extracorporeal Membrane Oxygenation Support for Antineutrophil Cytoplasmic Antibody-associated Vasculitides: An ELSO Registry Analysis.

ASAIO J 2021 Jul 27. Epub 2021 Jul 27.

From the Department of Pediatrics, Baylor College of Medicine, Houston, Texas Children's National Hospital, Washington, District of Columbia The Extracorporeal Life Support Organization, Ann Arbor, Michigan.

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides with pulmonary involvement include granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis, and can present with life-threatening pulmonary hemorrhage in up to 40% of patients. Mortality in those patients who require intubation and mechanical ventilation can reach 77%. Extracorporeal membrane oxygenation (ECMO) can be used to support these patients through definitive diagnosis and treatment, although minimizing the risk of ventilator-induced lung injury. Read More

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Extracorporeal Life Support Organization (ELSO) Guidelines for Follow-up After Neonatal and Pediatric Extracorporeal Membrane Oxygenation.

ASAIO J 2021 Jul 22. Epub 2021 Jul 22.

From the Department of Intensive Care and Pediatric Surgery, Erasmus MC-Sophia Children's Hospital University Medical Center Rotterdam, Rotterdam, The Netherlands Department of Pediatric Surgery/IC Children and Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands Division of Neurosciences, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, Tennessee Division of Pediatric Critical Care, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, Tennessee Heart and Lung Directorate, Great Ormond Street Hospital for Children NHS Foundation Trust and NIHR Great Ormond Street Hospital Biomedical Research Centre, London, United Kingdom Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas National University Health System, Singapore Department of Surgery, University of Florida, Gainesville, Florida Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Critical Care Medicine, SickKids Research Institute, The Hospital for Sick Children, University of Toronto, Canada.

Neonates and children who have survived critical illness severe enough to require extracorporeal membrane oxygenation (ECMO) are at risk for neurologic insults, neurodevelopmental delays, worsening of underlying medical conditions, and development of new medical comorbidities. Structured neurodevelopmental follow-up is recommended for early identification and prompt interventions of any neurodevelopmental delays. Even children who initially survive this critical illness without new medical or neurologic deficits remain at risk of developing new morbidities/delays at least through adolescence, highlighting the importance of structured follow-up by personnel knowledgeable in the sequelae of critical illness and ECMO. Read More

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Incidence of Acute Kidney Injury Is Lower in High-Risk Patients Undergoing Percutaneous Coronary Intervention Supported with Impella Compared to ECMO.

J Cardiovasc Transl Res 2021 Jul 29. Epub 2021 Jul 29.

Division of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine University Düsseldorf, Medical Faculty, Moorenstrasse 5, 40225, Düsseldorf, Germany.

Acute kidney injury (AKI) is a common complication post-PCI. Here, in a single-center observational registry, we compared the frequency of AKI in patients at elevated risk for AKI (based on Mehran risk stratification scoring) who underwent VA-ECMO- or Impella-supported high-risk PCI. A total of 28 patients scheduled for elective high-risk PCI with mechanical circulatory support were studied prospectively. Read More

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Pediatric Intensive Care Unit (PICU) Patient Room Design: Identifying Safety Risks in Mirrored Rooms Through a Graphical Systems Analysis.

HERD 2021 Jul 29:19375867211032921. Epub 2021 Jul 29.

Division of Pediatric Critical Care, Department of Pediatrics, 1367 Children's Healthcare of Atlanta, GA, USA.

Objective: The objectives of this study are to graphically depict specific clinical challenges encountered in a mirrored pediatric intensive care unit patient room and to represent potential solutions to address these challenges using a systems approach.

Background: The intensive care unit (ICU) patient room is a highly complex patient care environment where the design of the room must support patient care delivery safely and efficiently. There is a lack of research examining how ICU design elements interact with other system components to impact patient care. Read More

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Veno-arterial extracorporeal membrane oxygenation with concomitant Impella versus concomitant intra-aortic-balloon-pump for cardiogenic shock.

Perfusion 2021 Jul 28:2676591211033947. Epub 2021 Jul 28.

Cardiology Services, Department of Medicine, Queen Elizabeth Hospital, Kowloon, Hong Kong.

Introduction: The intra-aortic balloon pump (IABP) and Impella are left ventricular unloading devices with peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO) in place and later serve as bridging therapy when VA-ECMO is terminated. We aimed to determine the potential differences in clinical outcomes and rate of complications between the two combinations of mechanical circulatory support.

Methods: This was a retrospective, single institutional cohort study conducted in the intensive care unit (ICU) of Queen Elizabeth Hospital, Hong Kong. Read More

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Commentary: Combination effects of mechanical circulatory support: A cardinal consideration in venoarterial extracorporeal membrane oxygenation support!

JTCVS Tech 2021 Apr 6;6:90-91. Epub 2021 Jan 6.

Departments of Surgery, National Taiwan University Hospital, and National Taiwan University College of Medicine, Taipei, Taiwan.

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Descending aortic thrombosis and acute type B dissection during central extracorporeal membrane oxygenation: A word of caution.

JTCVS Tech 2021 Apr 20;6:85-87. Epub 2020 Nov 20.

Mechanical Circulatory Support Program at the Peter Munk Cardiac Centre, Division of Cardiovascular Surgery, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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Complete percutaneous decannulation from femoral venoarterial extracorporeal membrane oxygenation.

JTCVS Tech 2021 Apr 21;6:75-81. Epub 2020 Nov 21.

Division of Cardiac Surgery, Department of Surgery, University of Maryland School of Medicine, Baltimore, Md.

Objectives: To evaluate the clinical outcomes and perioperative complications associated with complete percutaneous decannulation of femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) with the MANTA closure device.

Methods: This is a retrospective analysis of a single surgeon consecutive series of 14 patients at a single center who underwent decannulation from VA-ECMO, 10 of whom underwent a percutaneous method of femoral cannula removal.

Results: After a mean duration of VA-ECMO support of 7. Read More

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Axillary artery cannulation for veno-arterial extracorporeal membrane oxygenation support in cardiogenic shock.

JTCVS Tech 2021 Feb 3;5:62-71. Epub 2020 Nov 3.

Division of Cardiothoracic Surgery, Department of Surgery, Westchester Medical Center, New York Medical College, Valhalla, NY.

Objective: To review the outcomes of axillary artery (AX) and femoral artery (FA) cannulation for veno-arterial extracorporeal membraneous oxygenation (VA-ECMO).

Methods: From 2009 to 2019, 371 patients who were supported with VA-ECMO for cardiogenic shock were compared based on the arterial cannulation site: AX (n = 218) versus FA (n = 153).

Results: Patients in the AX group were older (61 years vs 58 years,  = . Read More

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February 2021

Torrential Mitral Regurgitation After Transcatheter Edge-to-Edge Mitral Valve Repair.

JACC Case Rep 2021 Jan 20;3(1):69-73. Epub 2021 Jan 20.

Department of Medicine, Division of Cardiovascular Diseases, University of Mississippi Medical Center, Jackson, Mississippi, USA.

A patient with severe mitral regurgitation and chronic systolic heart failure taking inotropic support at home presents for transcatheter edge-to-edge mitral valve repair, complicated by torrential mitral regurgitation from damaged mitral leaflets requiring escalating mechanical circulatory support and ultimately expedited orthotopic heart transplantation. (). Read More

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January 2021

Recurrent Takotsubo Cardiomyopathy in a Patient With Hypertrophic Cardiomyopathy Leading to Cardiogenic Shock Requiring VA-ECMO.

JACC Case Rep 2020 Jun 17;2(7):1014-1018. Epub 2020 Jun 17.

Department of Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri.

Providing hemodynamic support for patients with hypertrophic cardiomyopathy and cardiogenic shock can be challenging because inotropic medications worsen intraventricular obstruction, and the effect of appropriate mechanical support remains undefined. We report a patient with hypertrophic cardiomyopathy in shock because of takotsubo cardiomyopathy requiring venoarterial extracorporeal membrane oxygenation and septal reduction for full recovery. (). Read More

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Supporting High-Risk Percutaneous Coronary Interventions With Mechanical Devices.

JACC Case Rep 2020 May 20;2(5):702-704. Epub 2020 May 20.

Spectrum Health/Michigan State University Cardiothoracic Surgery Fellowship, Grand Rapids, Michigan.

The use of mechanical circulatory support to maintain appropriate hemodynamics in high risk percutaneous coronary intervention cases is a new frontier. Treatment of cases that were once considered prohibitive may now be possible. Due to a paucity of data, guidelines offer no guidance about the use of mechanical circulatory support in such cases. Read More

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Kounis Syndrome Leading to Cardiac Arrest After Iodinated Contrast Exposure.

JACC Case Rep 2020 Apr 15;2(4):626-629. Epub 2020 Apr 15.

Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, Minnesota.

Immune-mediated coronary spasm, called Kounis syndrome (KS), is not rare but is underdiagnosed. In this report, we present a case of KS induced by iodinated contrast resulting in cardiac arrest, requiring temporary mechanical circulatory support. We show angiographic evidence of KS and outline commonly associated clinical features that may predict KS. Read More

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Rotablation of Heavily Calcified Left Main Stenosis and Aortic Valve Valvuloplasty Under ECMO Cardiopulmonary Support.

JACC Case Rep 2020 Dec 25;2(15):2448-2454. Epub 2020 Nov 25.

Department of Cardiology and Intensive Care Medicine, Medical Clinic II, Coburg Clinic, Coburg, Germany.

High-risk coronary intervention involving the left main coronary artery represents an indication for mechanical circulatory support in hemodynamically unstable patients. Extracorporeal membrane oxygenation permits adequate hemodynamic stabilization and myocardial recovery from life-threatening pulmonary and cardiac failure. Our case report demonstrates the importance of choosing the correct method of hemodynamic support in different case scenarios. Read More

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December 2020

Use of TandemHeart as Bridge to Recovery for Antibody-Mediated Rejection in a Heart Transplant Patient.

JACC Case Rep 2020 Dec 16;2(15):2358-2362. Epub 2020 Dec 16.

Section of Cardiomyopathy and Heart Transplantation, Division of Cardiology, John Ochsner Heart and Vascular Institute, Ochsner Clinic Foundation, The University of Queensland School of Medicine, New Orleans, Louisiana, USA.

Antibody-mediated rejection is a major cause of graft failure, mortality, and morbidity among cardiac transplant recipients. We present the first reported case of TandemHeart (LivaNova, Pittsburgh, Pennsylvania) used in the management of antibody-mediated rejection associated with cardiogenic shock. (). Read More

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December 2020

Combined Venoarterial ECMO and Impella-CP Circulatory Support for Cardiogenic Shock Due to Papillary Muscle Rupture.

JACC Case Rep 2020 Nov 14;2(14):2169-2172. Epub 2020 Oct 14.

Department of Medicine, Inova Heart and Vascular Institute, Falls Church, Virginia.

Papillary muscle rupture (PMR) is a catastrophic complication of acute myocardial infarction (AMI). We report on 3 consecutive patients with AMI cardiogenic shock due to PMR, treated with combined venoarterial extracorporeal membrane oxygenation and Impella-CP axial flow circulatory support as a bridge to definitive surgery. (). Read More

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November 2020

A Rare Case of Severe Nontropical Isolated Right Ventricular Endomyocardial Fibrosis.

JACC Case Rep 2020 Nov 18;2(13):2078-2084. Epub 2020 Nov 18.

Heart Lung Institute, The Prince Charles Hospital, Chermside, Australia.

We present a case of late presentation nontropical endomyocardial fibrosis isolated to the right ventricle and tricuspid valve (TV). In response to deteriorating hemodynamics, surgical debulking and TV removal were performed before initiation of centralized venoarterial extracorporeal membrane oxygenation support. Definitive endomyocardial resection with a TV prosthesis was then successfully completed. Read More

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November 2020

Percutaneous Transluminal Septal Myocardial Ablation for Hypertrophic Obstructive Cardiomyopathy Under Extracorporeal Membrane Oxygenation Support.

JACC Case Rep 2020 Oct 21;2(12):1917-1922. Epub 2020 Oct 21.

Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.

We report the case of a 70-year-old woman with hypertrophic obstructive cardiomyopathy, who was admitted because of severe heart failure and cardiogenic shock and mechanical support requiring extracorporeal membrane oxygenation. She recovered well by percutaneous transluminal septal myocardial ablation under the extracorporeal membrane oxygenation support and was discharged without complications. (). Read More

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October 2020

Newborn With Severely Depressed Left Ventricular Function: Acute Myocardial Infarction in a Newborn.

JACC Case Rep 2020 Oct 21;2(12):1837-1840. Epub 2020 Oct 21.

Division of Pediatric Cardiology and Pediatric Critical Care Medicine, Department of Pediatrics, Icahn School of Medicine at Mount Sinai and Kravis Children's Hospital at Mount Sinai, Mount Sinai Medical Center, New York, New York.

We describe a rare case of spontaneous coronary artery thrombosis in a newborn leading to rapid severe ventricular dysfunction. Early diagnosis is critical and management strategies are varied including hemodynamic support with extracorporeal membrane oxygenation, systemic/local thrombolytic therapy with tissue plasminogen activator, or surgical thrombectomy. (). Read More

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October 2020

Percutaneous Biventricular Hemodynamic Support Using Biatrial Extracorporeal Membrane Oxygenation.

JACC Case Rep 2020 Aug 8;2(10):1475-1479. Epub 2020 Jul 8.

Department of Cardiology, Henry Ford Hospital, Detroit, Michigan.

We describe the use of a fully percutaneous, biatrial extracorporeal membrane oxygenation circuit, to provide biventricular support with left heart unloading by using a single TandemHeart (LivaNova, London, United Kingdom) circuit during high-risk percutaneous coronary intervention. (). Read More

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Aortic Paravalvular Leak Repair: Can TAVR Be the Answer?

JACC Case Rep 2019 Dec 18;1(5):796-802. Epub 2019 Dec 18.

Kaleida Health, affiliated with the Department of Cardiology, University of Buffalo, Buffalo, New York.

A 71-year-old male with endocarditis mediated severe paravalvular leak and nonischemic cardiomyopathy underwent percutaneous repair attempts with a closure device followed by valve-in-valve transcatheter aortic replacement procedure. The case was complicated by cardiac arrest requiring hemodynamic support with Impella placement and secondary iatrogenic central aortic insufficiency requiring further intervention. (). Read More

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December 2019