238,892 results match your criteria ecg

[Cardiac diagnostics after ischemic stroke or transitory ischemic attack].

Dtsch Med Wochenschr 2021 Jun 15;146(12):801-808. Epub 2021 Jun 15.

Stroke is the most common cause of permanent disability and one of the most common causes of death. Cardio-embolic strokes are associated with a poor prognosis and a high risk of recurrence compared to other stroke etiologies. The most common source of cardiac embolism is atrial fibrillation which must be quickly identified to optimize secondary stroke prevention. Read More

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The significance of upright T wave in lead V1 in predicting myocardial ischemia A literature review.

J Electrocardiol 2021 Jun 1;67:103-106. Epub 2021 Jun 1.

Heart Hospital, Hamad Medical Corporation, Doha, Qatar.

Chest pain is still representing one of the most common and serious presentations to the emergency department worldwide. ECG is a crucial tool in evaluating patients with chest pain; however, only around 50% of patients with acute coronary syndrome (ACS) will have a diagnostic ECG upon their presentation; the rest may either have a completely normal ECG or what is called nonspecific ST segment and T wave (NSSTTW) changes, hence it is essential to recognize the subtle ECG changes and know its significance. One of the ECG changes that can be easily missed is when the T wave in V1 is upright, especially when it is either a Tall Upright T wave (TTV1) or a New Tall Upright T-wave (NTTV1). Read More

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Managing Atrial Fibrillation in Patients With Heart Failure and Reduced Ejection Fraction: A Scientific Statement From the American Heart Association.

Circ Arrhythm Electrophysiol 2021 Jun 15;14(6):e000078. Epub 2021 Jun 15.

Atrial fibrillation and heart failure with reduced ejection fraction are increasing in prevalence worldwide. Atrial fibrillation can precipitate and can be a consequence of heart failure with reduced ejection fraction and cardiomyopathy. Atrial fibrillation and heart failure, when present together, are associated with worse outcomes. Read More

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ECG for Screening Cardiac Abnormalities: The Premise and Promise of Machine Learning.

Circ Cardiovasc Imaging 2021 Jun 15;14(6):e012837. Epub 2021 Jun 15.

Division of Cardiology, Department of Medicine, West Virginia University Heart and Vascular Institute, Morgantown, WV, USA.

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Assessment of P- to delta-wave interval and its relationship with accessory pathway properties in patients with pre-excitation.

Cardiovasc J Afr 2021 May 19;32:1-5. Epub 2021 May 19.

Department of Cardiology, Samsun Training and Research Hospital, Health Sciences University, Samsun, Turkey. Email:

Background: The first clinical manifestation of the Wolff-Parkinson-White syndrome in previously asymptomatic individuals may be sudden cardiac death. The options for non-invasive risk stratification are limited in the current era beyond ambulatory rhythm monitoring and an exercise stress test. In our study, we sought to investigate whether there was a relationship between the shortest measured P- to delta-wave time interval (PDI) on the conduction properties of surface electrocardiogram and accessory pathways expressed as antegrade effective refractory period (APERP). Read More

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Comparative analysis of ischemic changes in electrocardiogram and coronary angiography results: A retrospective study.

Medicine (Baltimore) 2021 Jun;100(24):e26007

Peking University First Hospital, Beijing 100034, China.

Abstract: To improve the correct diagnosis rate of coronary heart disease and to explore the guiding value of electrocardiogram (ECG) ST-T ischemic changes in the clinical diagnosis of coronary heart disease.A retrospective analysis was conducted on a total of 310 cases who underwent a conventional 12-lead ECG, 12-lead dynamic ECG (DECG, Holter) with ST-T ischemic changes, and then coronary angiography (CA) within 1 week in Qingdao Sttarr Heart Hospital from June 2015 to April 2020 in the study. Ischemic ST-T changes were evaluated using conventional diagnostic criteria, and Judkins diagnostic criteria were used in CA. Read More

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Long-Term Prognostic Significance of Ventricular Repolarization Dispersion in Patients with Cardiac Sarcoidosis.

Am J Cardiol 2021 Jun 11. Epub 2021 Jun 11.

Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.

Cardiac sarcoidosis (CS) is frequently complicated by fatal ventricular arrhythmias. T-peak to T-end interval to QT interval ratio (TpTe/QT) on electrocardiograms (ECG) was proposed as a marker of ventricular repolarization dispersion. Although this ratio could be associated with the incidence of ventricular arrhythmias in cardiovascular diseases, its prognostic implication in patients with CS is unclear. Read More

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A Combination of Olanzapine and Samidorphan in Adults with Schizophrenia and Bipolar I Disorder: Overview of Clinical Data.

CNS Spectr 2021 Apr;26(2):170

Alkermes Pharma Ireland Limited, Dublin, Ireland.

Objectives: Olanzapine effectively treats schizophrenia and bipolar I disorder (BD-I); however, its use is hindered by significant weight gain. A combination of olanzapine and samidorphan (OLZ/SAM) is in development to provide the efficacy of olanzapine while mitigating olanzapine-associated weight gain through opioid-receptor blockade. Here, we summarize OLZ/SAM clinical data. Read More

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Deep Learning to Predict Cardiac Magnetic Resonance-Derived Left Ventricular Mass and Hypertrophy From 12-Lead ECGs.

Circ Cardiovasc Imaging 2021 Jun 15;14(6):e012281. Epub 2021 Jun 15.

Cardiovascular Disease Initiative (S.K., J.P.P., C.D.A., P.T.E., J.E.H., S.A.L.), Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge.

Background: Classical methods for detecting left ventricular (LV) hypertrophy (LVH) using 12-lead ECGs are insensitive. Deep learning models using ECG to infer cardiac magnetic resonance (CMR)-derived LV mass may improve LVH detection.

Methods: Within 32 239 individuals of the UK Biobank prospective cohort who underwent CMR and 12-lead ECG, we trained a convolutional neural network to predict CMR-derived LV mass using 12-lead ECGs (left ventricular mass-artificial intelligence [LVM-AI]). Read More

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[Clinical value of left ventricular strain analysis by cardiovascular magnetic resonance in patients with coronary chronic total occlusion].

Zhonghua Xin Xue Guan Bing Za Zhi 2021 Jun;49(6):601-609

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029,China.

To explore the clinical value of quantitatively assessment of left ventricular strain in patients with coronary chronic total occlusion (CTO) by cardiac magnetic resonance imaging (CMR)-feature tracking (CMR-FT) technique. In this retrospective and observation study, patients with single CTO, who underwent CMR examination in Beijing Anzhen Hospital from November 2014 to January 2019, were selected as case group (CTO group), and those without cardiovascular diseases defined by echocardiography, electrocardiogram (ECG) and clinical history and with normal CMR results were selected as healthy control group (control group). General clinical data including age, gender, discharge diagnosis, and the examination results of echocardiography and ECG were obtained from the electronic medical record system. Read More

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Effects of hCG administration on accessory corpus luteum formation and progesterone production in estrous-induced nulliparous Santa Inês ewes.

Anim Reprod 2018 Aug 16;15(2):135-139. Epub 2018 Aug 16.

Faculty of Veterinary Medicine, Fluminense Federal University, Niterói, RJ, Brazil.

The effect of hCG administration on accessory corpus luteum (ACL) formation, CL area, and plasma progesterone (P4) concentration (ng/mL) seven days after breeding was studied in nulliparous Santa Inês sheep. Intravaginal 60 mg MAP sponges were inserted into ewes for six days and 300 IU eCG i.m. Read More

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Evaluation of buffaloes' follicular dynamics and stress state under different ovulation synchronization protocols.

Anim Reprod 2018 Aug 16;15(2):102-107. Epub 2018 Aug 16.

Departamento de Reprodução Animal e Radiologia Veterinária, Faculdade de Medicina Veterinária e Zootecnia, Universidade Estadual "Júlio de Mesquita Filho" (UNESP), Botucatu, SP, Brasil.

The aims of the present study were to analyze the effect of different hormonal protocols using an implant containing Norgestomet, at the ovulation synchronization in buffaloes and to verify the effect of the stress caused by manipulation of the herd during the experiment. Twenty-four female Murrah breed buffaloes, lactating, multiparous, aged from three to eight years, with a body condition score of 3.5 or higher (0 to 5) and with more than 45 days post partum, were used. Read More

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Detection of myocardial ischemia by intracoronary ECG using convolutional neural networks.

PLoS One 2021 14;16(6):e0253200. Epub 2021 Jun 14.

Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Introduction: The electrocardiogram (ECG) is a valuable tool for the diagnosis of myocardial ischemia as it presents distinctive ischemic patterns. Deep learning methods such as convolutional neural networks (CNN) are employed to extract data-derived features and to recognize natural patterns. Hence, CNN enable an unbiased view on well-known clinical phenomenon, e. Read More

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Evaluation of Electrocardiographic Parameters and the Presence of Interatrial Block in Patients with Mad Honey Intoxication.

Cardiovasc Toxicol 2021 Jun 14. Epub 2021 Jun 14.

Department of Internal Medicine, Sakarya University Faculty of Medicine, Sakarya, Turkey.

Mad honey intoxication (MHI) is a food-induced clinical condition that usually presents with cardiovascular symptoms and can lead to life-threatening arrhythmias if not diagnosed and treated early. No data exist in the literature on the presence of interatrial block (IAB) after food intoxication. In our study, we sought to investigate atrioventricular electrocardiography (ECG) parameters and determine the frequency of IAB in patients with MHI. Read More

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Unheard Victims: Multidisciplinary Incidence and Reporting of Violence in an Emergency Department.

West J Emerg Med 2021 May 7;22(3):702-709. Epub 2021 May 7.

Mayo Clinic, Department of Emergency Medicine, Rochester, Minnesota.

Introduction: Workplace violence in the emergency department (ED) is a serious threat to staff and is likely to go unreported. We sought to identify the incidence of violence among staff at our academic ED over a six-month period.

Methods: An anonymous survey was sent to all ED staff, asking whether respondents had experienced verbal abuse or physical assault over the prior six months and whether they had reported it. Read More

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Fatal myopericarditis complicated with coronary vein perforation under the triple antithrombotic therapy: a case report.

Eur Heart J Case Rep 2021 Apr 24;5(4):ytab098. Epub 2021 Apr 24.

Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.

Background : Acute pericarditis generally follows a mild clinical course and is rarely fatal. Coronary vein involvement is rarely reported.

Case Summary : We report an autopsy case of cardiac tamponade from idiopathic myopericarditis due to coronary venous perforation under the triple antithrombotic therapy. Read More

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Left anterior descending/right coronary artery bifurcation angioplasty in a rare case of single coronary artery: a case report.

Eur Heart J Case Rep 2021 Apr 21;5(4):ytab047. Epub 2021 Apr 21.

Professor of Medicine & Interventional Cardiologist, Department of Cardiology, Military Hospital, Jaipur-302016, India.

Background: Single coronary artery (SCA) is a rare congenital coronary anomaly with incidence of 8-66 per 100 000 cases. Percutaneous coronary intervention (PCI) in patients with SCA is technically challenging. This is a case of bifurcation angioplasty involving left anterior descending/right coronary artery (LAD/RCA) in a patient with SCA and 1-year follow-up with computed tomography coronary angiography (CTCA). Read More

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The validity and reliability of an open source biosensing board to quantify heart rate variability.

Heliyon 2021 Jun 27;7(6):e07148. Epub 2021 May 27.

Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada.

Background: Heart rate variability (HRV) is a popular tool to quantify autonomic function. However, this typically requires an expensive 3-12 lead electrocardiogram (ECG) and BioAmp system. This investigation sought to determine the validity and reliability of an OpenBCI cyton biosensing board (open source) for accurately quantifying HRV. Read More

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Early systolic lengthening by speckle tracking echocardiography predicts outcome after coronary artery bypass surgery.

Int J Cardiol Heart Vasc 2021 Jun 28;34:100799. Epub 2021 May 28.

Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Denmark.

Background: Early systolic lengthening (ESL), a paradoxical stretch of myocardial fibers, has been linked to loss of myocardial viability and contractile dysfunction. We assessed the long-term prognostic potential of ESL in coronary artery bypass graft (CABG) patients.

Methods: We retrospectively included patients (n = 709; mean age 68 years; 85% men) who underwent speckle tracking echocardiography (median 15 days) prior to CABG. Read More

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Young athletes: Preventing sudden death by adopting a modern screening approach? A critical review and the opening of a debate.

Int J Cardiol Heart Vasc 2021 Jun 28;34:100790. Epub 2021 May 28.

Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA.

Preventing sudden cardiac death (SCD) in athletes is a primary duty of sports cardiologists. Current recommendations for detecting high-risk cardiovascular conditions (hr-CVCs) are history and physical examination (H&P)-based. We discuss the effectiveness of H&P-based screening versus more-modern and accurate methods. Read More

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Fixed-time artificial insemination protocols on brazilian locally adapted breed gilts on ovulatory response and embryo production.

Anim Reprod 2021 May 28;18(1):e20200776. Epub 2021 May 28.

Embrapa Recursos Genéticos e Biotecnologia, Brasília, DF, Brasil.

The aim of this study was to use estrus synchronization protocols to favor fixed-time artificial insemination and consequently fixed-time embryo collection, and increase embryo production using eCG, in gits. In a cross over design, nine breed gilts were subjected to 18 days of oral progesterone; P4 group did not receive any further; GnRH group received 25µg of GnRH 104 hours after the final application of P4; and eCG+GnRH group received 1000IU of eCG 24 hours after the final P4 in addition to GnRH for subsequent embryo collection, that was performed six days after first AI, by laparotomy. Artificial insemination was performed after 12 and 24 hours of estrus in P4 group, and 128 and 144 hours in GnRH and eCG+GnRH groups. Read More

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The Association Between Heart Rate Variability and 90-Day Prognosis in Patients With Transient Ischemic Attack and Minor Stroke.

Front Neurol 2021 28;12:636474. Epub 2021 May 28.

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Low heart rate variability (HRV) is known to be associated with increased all-cause, cardiovascular, and cerebrovascular mortality but its association with clinical outcomes in patients with transient ischemic attack (TIA) or minor stroke is unclear. We selected TIA and minor stroke patients from a prospective registration study. From each continuous electrocardiograph (ECG) record, each QRS complex was detected and normal-to-normal (N-N) intervals were determined. Read More

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Dominant-Negative Effect of an Brugada Syndrome Variant.

Front Physiol 2021 28;12:661413. Epub 2021 May 28.

INSERM, UMR_S 1166 ICAN, Paris, France.

Loss-of-function mutations in the cardiac Na channel α-subunit Na1.5, encoded by , cause Brugada syndrome (BrS), a hereditary disease characterized by sudden cardiac death due to ventricular fibrillation. We previously evidenced the dominant-negative effect of the BrS Na1. Read More

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A non-invasive system to measure heart rate in hard-shelled sea turtles: potential for field applications.

Philos Trans R Soc Lond B Biol Sci 2021 Aug 14;376(1830):20200222. Epub 2021 Jun 14.

Atmosphere and Ocean Research Institute, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8564, Japan.

To measure the heart rate of unrestrained sea turtles, it has been believed that a probe must be inserted inside the body owing to the presence of the shell. However, inserting the probe is invasive and difficult to apply to animals in the field. Here, we have developed a non-invasive heart rate measurement method for some species of sea turtles. Read More

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Pharmacokinetics of daridorexant, a dual orexin receptor antagonist, are not affected by renal impairment.

Clin Transl Sci 2021 Jun 13. Epub 2021 Jun 13.

Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

The aim of this study was to evaluate the impact of renal impairment on the pharmacokinetics (PK), safety, and tolerability of daridorexant, a dual orexin receptor antagonist (DORA) intended for the treatment of insomnia. A single-center, open-label study evaluated the PK of daridorexant in patients with severe renal function impairment (SRFI, determined by creatinine clearance using the Cockcroft-Gault equation; n=8) not on dialysis, and in matched control subjects (based on sex, age, and body weight; n=7). A single oral dose of daridorexant 25 mg was orally administered in the morning. Read More

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Artificial Intelligence-Augmented Electrocardiogram Detection of Left Ventricular Systolic Dysfunction in the General Population.

Mayo Clin Proc 2021 Jun 10. Epub 2021 Jun 10.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. Electronic address:

Objective: To validate an artificial intelligence-augmented electrocardiogram (AI-ECG) algorithm for the detection of preclinical left ventricular systolic dysfunction (LVSD) in a large community-based cohort.

Methods: We identified a randomly selected community-based cohort of 2041 subjects age 45 years or older in Olmsted County, Minnesota. All participants underwent a study echocardiogram and ECG. Read More

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Assessment of safety and tolerability of remogliflozin etabonate (GSK189075) when administered with total daily dose of 2000 mg of metformin.

BMC Pharmacol Toxicol 2021 Jun 13;22(1):34. Epub 2021 Jun 13.

Glenmark Pharmaceuticals Ltd, Mumbai, India.

Background: Patients with type 2 diabetes mellitus (T2DM) are characterized by an elevated glycemic index and are at a higher risk for complications such as cardiovascular disease, nephropathy, retinopathy and peripheral neuropathy. Normalization of glycemic index can be achieved by dosing combinations of metformin with other anti-diabetic drugs. The present study (Clintrials number NCT00519480) was conducted to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of remogliflozinetabonate, an SGLT2 inhibitor, withdoses (500 mg and 750 mg BID) greater than the commercial dose (100 mg BID)in combination with metformin with minimum daily dose of 2000 mg given in two divided doses. Read More

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Seizure-induced Torsades de pointes:In a canine drug-induced long-QT1 model.

J Pharmacol Toxicol Methods 2021 Jun 10:107086. Epub 2021 Jun 10.

Janssen Research & Development, Division of Janssen Pharmaceutica N.V., Turnhoutseweg 30, 2340 Beerse, Belgium. Electronic address:

Introduction: People with epilepsy are at heightened risk of sudden death compared to the general population. The leading cause of epilepsy-related premature mortality is a sudden unexpected death in epilepsy (SUDEP). The mechanism of SUDEP remains largely unresolved and the lack of preclinical models to study the potential mechanism underlying SUDEP is a problem. Read More

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A retrospective evaluation of the indications, complications, and outcomes associated with epicardial pacemakers in 20 cats from a single institution.

J Vet Cardiol 2021 May 13;36:89-98. Epub 2021 May 13.

Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Dr. Madison, WI 53706, USA.

Introduction: The objective of this retrospective study was to describe the indications, complications, and long-term outcomes in a group of cats that received an epicardial pacing (EP) system.

Animals: Twenty client-owned cats.

Materials And Methods: Medical records were reviewed for signalment, presenting complaint, primary electrocardiogram (ECG) diagnosis, presence of structural heart disease, presence of congestive heart failure (CHF), presence of major or minor complications, and survival time. Read More

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The Relationship Between Frontal QRS-T Angle and the Severity of Newly Diagnosed Chronic Obstructive Pulmonary Disease.

Int J Clin Pract 2021 Jun 12:e14500. Epub 2021 Jun 12.

Department of Cardiology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.

Background: Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent airflow restriction and respiratory symptoms. Studies demonstrated that cardiac arrhythmias and cardiovascular mortality increased in these patients due to altered myocardial repolarization. Frontal QRS-T angle is a novel marker of myocardial depolarization and repolarization heterogeneity. Read More

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