176,494 results match your criteria early adolescence


Good Engraftment but Quality and Donor Concerns for Cryopreserved HPC Products Collected During the COVID-19 Pandemic.

Transplant Cell Ther 2021 Sep 24. Epub 2021 Sep 24.

Department of Haematology and Bone Marrow Transplantation, St Vincent's Hospital, Sydney, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Australia.

Background: Changes to donor availability, collection centre capacity and travel restrictions during the early phase of the COVID-19 pandemic led to routine cryopreservation of most unrelated donor products for haematopoietic transplantation prior to the recipient commencing the conditioning regimen.

Objective: We investigated the effect of this change on unrelated donor product quality and clinical outcomes.

Study Design: Product information was requested from transplant centres in Australia and New Zealand, and clinical outcome data from the Australasian Bone Marrow Transplant Recipient Registry (ABMTRR). Read More

View Article and Full-Text PDF
September 2021

Gathering Is Not Only for Girls : No Influence of Energy Expenditure on the Onset of Sexual Division of Labor.

Hum Nat 2021 Sep 27. Epub 2021 Sep 27.

National Research Center On Human Evolution (CENIEH), 09002, Burgos, Spain.

In some small-scale societies, a sexual division of labor is common. For subadult hunter-gatherers, the onset of this division dates to middle childhood and the start of puberty; however, there is apparently no physiological explanation for this timing. The present study uses an experimental approach to evaluate possible energetic differences by sex in gathering-related activities. Read More

View Article and Full-Text PDF
September 2021

Characterization and prediction of clinical pathways of vulnerability to psychosis through graph signal processing.

Elife 2021 Sep 27;10. Epub 2021 Sep 27.

Developmental Imaging and Psychopathology Laboratory, University of Geneva School of Medicine, Geneva, Switzerland.

Causal interactions between specific psychiatric symptoms could contribute to the heterogenous clinical trajectories observed in early psychopathology. Current diagnostic approaches merge clinical manifestations that co-occur across subjects and could significantly hinder our understanding of clinical pathways connecting individual symptoms. Network analysis techniques have emerged as alternative approaches that could help shed light on the complex dynamics of early psychopathology. Read More

View Article and Full-Text PDF
September 2021

Colorectal carcinoma in children and adolescents.

Arch Argent Pediatr 2021 Oct;119(5):e487-e498

Servicio de Hematología y Oncología, Hospital de Pediatría S.A.M.I.C. "Prof. Dr. Juan P. Garrahan", Ciudad Autónoma de Buenos Aires, Argentina.

Although colorectal carcinoma (CRC) is the third most common type of cancer in adults, only 1-4 % of cases are reported in individuals younger than 25-30 years. Its presentation is usually confused with other diseases, leading to significant delays in diagnosis. Given its low incidence, few pediatricians will see a case throughout their practice. Read More

View Article and Full-Text PDF
October 2021

Case Report: Perioperative Kounis Syndrome in an Adolescent With Congenital Glaucoma.

Front Cardiovasc Med 2021 10;8:676188. Epub 2021 Sep 10.

Department of Pediatrics, Meyer Children's Hospital, Florence, Italy.

A 12-year-old male patient suffering from congenital glaucoma developed bradycardia, left ventricular failure, and hypotension after induction of anesthesia. Electrocardiography and echocardiography revealed a complete normalization of ECG and a complete spontaneous recovery in the cardiac function 72 hours from the beginning of the clinical manifestations, while cardiac Magnetic Resonance Imaging was performed, and coronary Computed Tomography scan revealed a myocardial bridge of a tract of the left anterior descendent coronary artery. Diagnosis of Kounis syndrome (KS) was made, a relatively novel, under-recognized clinical condition, defined as the manifestation of an acute coronary syndrome accompanied by mast cell activation and platelet aggregation involving interrelated and interacting inflammatory cells in the setting of allergic, hypersensitivity, anaphylactic or anaphylactoid insults. Read More

View Article and Full-Text PDF
September 2021

Accounting for Biomechanical Measures from Musculoskeletal Simulation of Upright Posture Does Not Enhance the Prediction of Curve Progression in Adolescent Idiopathic Scoliosis.

Front Bioeng Biotechnol 2021 10;9:703144. Epub 2021 Sep 10.

LABS-Laboratory of Biological Structures Mechanics, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

A major clinical challenge in adolescent idiopathic scoliosis (AIS) is the difficulty of predicting curve progression at initial presentation. The early detection of progressive curves can offer the opportunity to better target effective non-operative treatments, reducing the need for surgery and the risks of related complications. Predictive models for the detection of scoliosis progression in subjects before growth spurt have been developed. Read More

View Article and Full-Text PDF
September 2021

Interrelationship Between Age, Gender, and Weight Status on Motor Coordination in Italian Children and Early Adolescents Aged 6-13 Years Old.

Front Pediatr 2021 10;9:738294. Epub 2021 Sep 10.

Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Science and Human Movement, University of Palermo, Palermo, Italy.

Although numerous evidences reported a negative correlation between motor coordination (MC) and overweight/obesity in children and adolescents, the interrelationship between age, gender, and weight status is still debatable. Hence, the aim of this cross-sectional study was to examine the association between MC and weight status according to age and gender across childhood and early adolescence in a large sample of Italian elementary and middle school students. A number of 1961 Italian school students (1,026 boys, 935 girls) was stratified in three consecutive age groups (6-7, 8-10, and 11-13 years) and four weight status categories (underweight, normal weight, overweight, and obese) according to Cole's body mass index (BMI) cut-off points for children. Read More

View Article and Full-Text PDF
September 2021

Behavioural equivalents of schizophrenia in people with intellectual disability and autism spectrum disorder. A selective review.

Int J Dev Disabil 2021 18;67(5):310-317. Epub 2021 Sep 18.

National Advisory on Mental Health in Intellectual Disability, Oslo University, Oslo, Norway.

Assessment of schizophrenia (SCZ) in people with autism spectrum disorder (ASD) is complicated due to confounding symptoms between ASD and SCZ. These confounding factors are aggravated when the patient has sparse verbal skills. A selective review was conducted to identify behavioural equivalents when assessing SCZ in individuals with ASD with sparse verbal skills, from 16 years of age. Read More

View Article and Full-Text PDF
September 2021

Early-Life Exposure to Per- and Poly-Fluorinated Alkyl Substances and Growth, Adiposity, and Puberty in Children: A Systematic Review.

Front Endocrinol (Lausanne) 2021 9;12:683297. Epub 2021 Sep 9.

Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, South Korea.

Per- or polyfluoroalkyl substances (PFAS), a family of synthetic polyfluorinated compounds, are widely used in consumer products. Ubiquitous exposures to PFAS, in consideration of their persistence, bioaccumulation potential, and toxicities have led to concerns regarding possible harmful effects during critical periods of development in early-life and long-term consequences on health. The potential effects of PFAS depend on various factors including the type of PFAS and the timing and level of exposure. Read More

View Article and Full-Text PDF
September 2021

Historical Patterns of Diagnosis, Treatments, and Outcome of Epilepsy Associated With Tuberous Sclerosis Complex: Results From TOSCA Registry.

Front Neurol 2021 8;12:697467. Epub 2021 Sep 8.

Cardiology Clinical Academic Group, Molecular and Clinical Sciences Research Centre, St Georges University of London, London, United Kingdom.

Epilepsy is the most common neurological manifestation in individuals with tuberous sclerosis complex (TSC). However, real-world evidence on diagnosis and treatment patterns is limited. Here, we present data from TuberOus Sclerosis registry to increase disease Awareness (TOSCA) on changes in patterns of epilepsy diagnosis, treatments, and outcomes over time, and detailed epilepsy characteristics from the epilepsy substudy. Read More

View Article and Full-Text PDF
September 2021

Peer Group Embeddedness and Academic Motivation: A Developmental Perspective.

Authors:
Marion Reindl

Front Psychol 2021 9;12:701600. Epub 2021 Sep 9.

Educational Science, Paris Lodron University of Salzburg, Salzburg, Austria.

The present study focused on the increasing importance of peer group embeddedness on domain-specific academic motivation (intrinsic value and mastery goals) over the course of early adolescence. In this regard, two important research questions were investigated: (1) Does a change in peer group embeddedness influence a change in student intrinsic value and mastery goals? (2) Does this influence increase over the course of early adolescence? The research questions were investigated based on a five-wave longitudinal study over two school years (seventh and eighth grade) in Germany. The final sample comprised 349 students. Read More

View Article and Full-Text PDF
September 2021

An Impact Analysis of the Early Months of the COVID-19 Pandemic on Mental Health in a Prospective Cohort of Canadian Adolescents.

J Adolesc Health 2021 Aug 4. Epub 2021 Aug 4.

Projet COMPASS-Québec, VITAM - Centre de recherche en santé durable de l'Université Laval, Quebec City, Quebec, Canada; Department of Social and Preventive Medicine, Faculty of Medicine - Université Laval, Ferdinand Vandry Pavillon, Quebec City, Quebec, Canada.

Purpose: The impact of the COVID-19 pandemic on adolescent mental health is a global concern; however, most research is cross-sectional or started after the pandemic response began and thus unable to evaluate within-individual change. The purpose of this prospective study was to evaluate the effect of the initial COVID-19 response on adolescent mental health and ill-health as a natural experiment.

Methods: We used 3-year linked data from the COMPASS study, including 7,653 Canadian (Quebec, Ontario) adolescents from which 2,099 completed surveys in all three waves (pre-COVID-19 [2018 and 2019] and online [May-July 2020], 2-3 months into the pandemic). Read More

View Article and Full-Text PDF

[Diagnostic criteria for obstructive sleep apnea syndrome in adolescent].

Rev Mal Respir 2021 Sep 23. Epub 2021 Sep 23.

Unité de sommeil pédiatrique, ESEFNP, HFME, hospices civils de Lyon, U1028, CRNL, université Lyon 1, 59, boulevard Pinel, 69500 Lyon, France. Electronic address:

The obstructive sleep apnoea syndrome (OSAS) affects 1-4% of adolescents. It represents a transitional stage between paediatric and adult OSA and is characterized by specific symptoms. BACKGROUND: The persistence of childhood OSAS during adolescence is not frequent. Read More

View Article and Full-Text PDF
September 2021

[Early intervention in bipolar affective disorders: Why, when and how].

Encephale 2021 Sep 23. Epub 2021 Sep 23.

University Grenoble Alpes, 38000 Grenoble, France; Inserm, U1216, 38000 Grenoble, France; Adult Psychiatry Department, CHU Grenoble Alpes, 38000 Grenoble, France; Adult Psychiatry Department, Early Intervention in Psychosis [CALIPSO service], CH Alpes-Isère, 38000 Saint-Egrève, France. Electronic address:

Objectives: Bipolar disorder (BD) is a chronic and severe psychiatric disease. There are often significant delays prior to diagnosis, and only 30 to 40 % of patients will experience complete remission. Since BD occurs most often at a young age, the disorder can seriously obstruct future socio-professional development and integration. Read More

View Article and Full-Text PDF
September 2021

Socioeconomic inequalities in early initiation and exclusive breastfeeding practices in Bangladesh: findings from the 2018 demographic and health survey.

Int Breastfeed J 2021 Sep 26;16(1):73. Epub 2021 Sep 26.

Health Equity Laboratory, School of Health Sciences, Western Sydney University, Locked Bag 1797, Penrith, NSW, 2751, Australia.

Background: Optimal breastfeeding practices including early initiation of breastfeeding and exclusive breastfeeding (EBF) are associated with positive health outcomes. Socioeconomic inequalities in key breastfeeding indicators may play a role in the prevalence of breastfeeding practices. The objective of this study was to examine the socioeconomic inequalities in early initiation of breastfeeding and EBF practices in Bangladesh based on the 2018 Bangladesh Demographic and Health Survey (BDHS). Read More

View Article and Full-Text PDF
September 2021

The role of weight- and appearance-related discrimination on eating disorder symptoms among adolescents and emerging adults.

BMC Public Health 2021 Sep 26;21(1):1751. Epub 2021 Sep 26.

Department of Epidemiology and Health Monitoring, Robert Koch Institute, Nordufer 20, 13353, Berlin, Germany.

Background: Eating disorder symptoms (EDs) have been discussed as a prominent problem among late adolescent girls with serious health risks and long-term consequences. However, there is a lack of population-based evidence on EDs comprising the age range from early adolescence to emerging adulthood as well as considering both females and males equally. Additionally, the differential role of a comprehensive set of several relevant risk factors and particularly weight- and appearance-related discrimination warrants further attention. Read More

View Article and Full-Text PDF
September 2021

Dietary sialylated oligosaccharides in early-life may promote cognitive flexibility during development in context of obesogenic dietary intake.

Nutr Neurosci 2021 Sep 27:1-18. Epub 2021 Sep 27.

Brain Health, Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., 1005 Lausanne, Switzerland.

Oligosaccharides found in mammalian milk have shown the potential to alter brain development across multiple species. The diversity and concentration of these oligosaccharides is species-specific and varies greatly between individuals, thus understanding their role in cognitive development is warranted. We investigated the impact of early life dietary fucosylated/neutral or sialylated human milk oligosaccharides (HMO) on behaviours in tasks assessing anxiety, motivation, appetite, learning, and memory. Read More

View Article and Full-Text PDF
September 2021

Early life Western diet-induced memory impairments and gut microbiome changes in female rats are long-lasting despite healthy dietary intervention.

Nutr Neurosci 2021 Sep 27:1-17. Epub 2021 Sep 27.

Neuroscience Graduate Program, University of Southern California, Los Angeles, CA, USA.

Objective: Western diet consumption during adolescence results in hippocampus (HPC)-dependent memory impairments and gut microbiome dysbiosis. Whether these adverse outcomes persist in adulthood following healthy dietary intervention is unknown. Here we assessed the short- and long-term effects of adolescent consumption of a Western diet enriched with either sugar or both sugar and fat on metabolic outcomes, HPC function, and gut microbiota. Read More

View Article and Full-Text PDF
September 2021

How Wisdom Emerges from Intellectual Development: A Developmental/Historical Theory for Raising Mandelas.

J Intell 2021 Sep 21;9(3). Epub 2021 Sep 21.

Department of Turkish and Middle Eastern Studies, University of Cyprus, Kallipoleos 75, Nicosia 1678, Cyprus.

This paper invokes cognitive developmental theory as a means for preparing citizens to deal with and resolve conflicts within or across nations. We take the centuries-old Greek-Turkish dispute as an example. We first outline a theory of intellectual development postulating that mental changes emerge in response to changing developmental priorities in successive life periods, namely, interaction control in infancy, attention control and representational awareness in preschool, inferential control and cognitive management in primary school, and advanced forms of reasoning and self-evaluation in adolescence. Read More

View Article and Full-Text PDF
September 2021

Sigmoid volvulus in an adolescent female: A case report.

Int J Surg Case Rep 2021 Sep 22;87:106430. Epub 2021 Sep 22.

Faculty of Clinical Medicine and Dentistry, Department of Surgery, Kampala International University Western Campus, Ishaka-Bushenyi, Uganda; Department of Surgery, Jinja Regional Referral Hospital, Jinja, Uganda.

Introduction And Importance: Sigmoid volvulus is a rare cause of intestinal obstruction in children and adolescent population. It's considered a disease of the elderly with a widely varying incidence worldwide. It is more common in areas referred to as "volvulus belt" (Middle East, Africa, the Indian subcontinent, Turkey, and South America). Read More

View Article and Full-Text PDF
September 2021

No association between maternal and child PFAS concentrations and repeated measures of ADHD symptoms at age 2½ and 5 years in children from the Odense Child Cohort.

Neurotoxicol Teratol 2021 Sep 23:107031. Epub 2021 Sep 23.

Department of Clinical Pharmacology, Pharmacy and Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

Introduction: The potential impact of exposure to perfluoroalkyl substances (PFAS) on childhood Attention-Deficit Hyperactivity-Disorder (ADHD) is unclear and deserves scrutiny. The majority of previously conducted longitudinal studies found no association between maternal serum-PFAS concentrations and ADHD symptoms in the offspring, but some studies observed possible associations with postnatal PFAS exposures, mainly in girls.

Objective: To investigate the association between maternal and child serum concentrations of five PFAS and symptoms of ADHD at ages 2½ and 5 years. Read More

View Article and Full-Text PDF
September 2021

Relationship between Early Maladaptive Schemas and Anxiety in Adolescence and Young Adulthood: A systematic review and meta-analysis.

J Affect Disord 2021 Sep 17. Epub 2021 Sep 17.

School of Psychology & Clinical Language Sciences, University of Reading, United Kingdom.

Background: Early maladaptive schemas (EMS) are self-perpetuating dysfunctional cognitive structures that have been linked with youth psychological health and play a significant role in developing and maintaining psychological distress, including anxiety symptoms.

Method: The present meta-analysis synthesises the existing literature to evaluate the strength of association between EMS and anxiety symptoms among adolescents and young adults (aged 10-29 years). The systematic literature search was carried out in October 2019 using six different databases. Read More

View Article and Full-Text PDF
September 2021

Smartphone application for adolescents with anorexia nervosa: an initial acceptability and user experience evaluation.

BMC Psychiatry 2021 Sep 25;21(1):467. Epub 2021 Sep 25.

Service Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, CHU de Toulouse, Hôpital Purpan, Place du Dr Baylac, TSA 40031, 31059, Toulouse cedex 9, France.

Background: Anorexia Nervosa (AN) is a key target for E-Health programs considering the many barriers hindering patients' access to care and the disorder's severity. Although these programs have become more common and effective, they often have low adherence, especially among youth. This can hinder their implementation and effectiveness in real-world settings. Read More

View Article and Full-Text PDF
September 2021

Symptom and clinical recovery outcomes for pediatric concussion following early physical activity.

J Neurosurg Pediatr 2021 Sep 24:1-8. Epub 2021 Sep 24.

3Sports Medicine Center, Children's Hospital Colorado, Aurora.

Objective: Recent research supports initiating physical activity as soon as 24 to 48 hours after concussion to reduce persistent postconcussive symptoms. However, this practice has not been widely adopted. The objective of this study was to evaluate the association of early physical activity with patient-reported and functional outcomes for pediatric patients following a concussion. Read More

View Article and Full-Text PDF
September 2021

Pulmonary valve reconstruction by allograft replacement of underdeveloped anterior leaflet in case of late combined pulmonary restenosis after early primary repair.

Int J Surg Case Rep 2021 Sep 15;87:106410. Epub 2021 Sep 15.

Center of Cardiac Surgery (OOO), Chelyabinsk, Russian Federation.

Introduction: The native pulmonary valve (PV) reconstruction is an attractive alternative to a replacement but is challenging due to the systematic underdevelopment of the valve structures in congenital heart diseases. The partial replacement of underdeveloped parts of the valve and saving of well-developed may have advantages versus replacing the whole valve in terms of durability and patient outgrowth of the prosthesis.

Case Presentation: This report describes a case of the PV reconstruction by allograft replacement of an underdeveloped anterior leaflet in an adolescent patient who previously corrected pulmonary stenosis during the first year of her life. Read More

View Article and Full-Text PDF
September 2021

Very early-onset Obsessive-Compulsive Disorder in pre-schoolers: A prospective case series.

Asian J Psychiatr 2021 Sep 17;65:102857. Epub 2021 Sep 17.

NIMHANS, Bengaluru 560029, Karnataka, India.

Normative Obsessive-compulsive (OC) like behaviors can be common in early childhood. Very young children rarely can present with significantly impairing OC phenomenon associated with severe accommodative behaviors, which may warrant interventions. We describe three pre-schoolers with an onset of impairing OC symptoms at 28-, 21-, and 36-months of ages. Read More

View Article and Full-Text PDF
September 2021

Family functioning as a moderator in the relation between perceived stress and psychotic-like experiences among adolescents during COVID-19.

Compr Psychiatry 2021 Sep 17;111:152274. Epub 2021 Sep 17.

Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; China National Clinical Research Center on Mental Disorders, Changsha, Hunan, China. Electronic address:

Background: The COVID-19 pandemic has increased psychological stress among adolescents, and the relation between perceived stress (PS) and psychotic-like experiences (PLEs) has been well-established. However, little is known about the role of family functioning (FF) in this relation, especially when adolescents experienced the extended lockdown period with family members.

Methods: A total of 4807 adolescents completed this retrospective paper-and-pencil survey after school reopening between May 14th and June 6th, 2020 in Hunan Province, China. Read More

View Article and Full-Text PDF
September 2021

Cooperate or aggress? An opponent's tendency to cooperate modulate the neural dynamics of interpersonal cooperation.

Neuropsychologia 2021 Sep 21:108025. Epub 2021 Sep 21.

School of Economics and Management, Fuzhou University, Fuzhou 350108, China; Institute of Psychological and Cognitive Sciences, Fuzhou University, Fuzhou, China. Electronic address:

Humans are social animals and need to cooperate to survive. However, individuals are not cooperative in every social interaction, and their cooperation may depend on social context. The present study used a social dilemma game to investigate whether an opponent's tendency to be cooperative over time influenced a player's behavior and neural response to outcomes in the game. Read More

View Article and Full-Text PDF
September 2021

An Epidepic in the Pandemic: The Most Difficult Challenge for Young Adolescents.

Psychiatr Danub 2021 Sep;33(Suppl 9):142-147

Departmentt of Psychology, University Magna Graecia, Viale Europa, 88100 Catanzaro, Italy,

The pandemic due to COVID-19 has had a huge psychological impact on individuals all over the world, in particular the international literature is noting an increase in pathologies among children and adolescents adolescenti (Pappa et al. 2020, Keles et al. 2020, Pigaiani et al. Read More

View Article and Full-Text PDF
September 2021