6,622 results match your criteria e-cigarette

Adolescent Vaping and COVID-19: When an Epidemic Meets a Pandemic.

S D Med 2021 Feb;74(2):76-78

Avera Medical Group, University Psychiatry Associates, Sioux Falls, South Dakota.

National epidemiological studies indicate that vaping or e-cigarette use has increased in alarming proportions among American adolescents. In vaping, a battery-powered device heats up a liquid into an aerosol which is inhaled by the user. The aerosol, commonly referred to as vapor, usually contains nicotine, flavoring, marijuana along with other chemicals and substances. Read More

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February 2021

Changes in Biomarkers of Cigarette Smoke Exposure After 6 Days of Switching Exclusively or Partially to Use of the JUUL System with Two Nicotine Concentrations: A Randomized Controlled Confinement Study in Adult Smokers.

Nicotine Tob Res 2021 Jun 23. Epub 2021 Jun 23.

Pinney Associates, Inc., Bethesda MD.

Introduction: Evidence suggests that cigarette smokers who switch to electronic nicotine delivery systems (ENDS) reduce their exposure to harmful toxicants and carcinogens. It is unclear if dual use is associated with decreases in exposure to toxicants.

Methods: This parallel-group confinement study assessed changes in biomarkers of exposure (BOEs) over six days among healthy adult smokers who were randomized into 1 of 11 study groups: eight JUUL-brand System (JUUL) groups (4 JUUL flavors [Virginia Tobacco, Menthol, Mint, Mango] × 2 nicotine concentrations [5. Read More

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Effects of combined THC and heroin vapor inhalation in rats.

Psychopharmacology (Berl) 2021 Jun 23. Epub 2021 Jun 23.

Department of Neuroscience, The Scripps Research Institute, La Jolla, CA, USA.

Rationale: Opioids are effective medications, but they have several key limitations including the development of tolerance, establishment of dependence, diversion for non-medical use, and the development of addiction. Therefore, any drugs which act in an additive or synergistic fashion with opioids to address medical applications have the potential to reduce opioid-related harms.

Objectives: To determine if heroin and Δ-tetrahydrocannabinol (THC) interact in an additive or independent manner to alter nociception, body temperature, and spontaneous locomotor activity when inhaled or injected. Read More

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Rising Vape Pod Popularity Disrupted Declining Use of Electronic Nicotine Delivery Systems among Young Adults in Texas, USA from 2014-2019.

Addiction 2021 Jun 22. Epub 2021 Jun 22.

Health Promotion and Behavioral Sciences, The University of Texas Health Science Center at Houston School of Public Health, in Austin, 1616 Guadalupe Street, Suite 6.300, Austin, TX, 78701.

Aims: To examine the longitudinal trajectory of young Texan (USA) adults' Electronic Nicotine Delivery Systems (ENDS) use from 2014-2019, and to determine if there are changes in the trajectory among younger and older young adults post-2017, when vape pods surged in popularity in the United States.

Design: Nine-wave longitudinal study, with 6 months between each of the first eight waves and 1 year between the last two waves. Discontinuous, or piecewise, growth curve models were used to test the hypotheses that a) the overall current/past 30-day ENDS use trajectory would decline from 2014-spring 2017, but then increase from fall 2017-2019 and b) the increasing trajectory from 2017-2019 would occur only for younger participants, but not older participants. Read More

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Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid.

Arch Toxicol 2021 Jun 22. Epub 2021 Jun 22.

ABF Analytisch-Biologisches Forschungslabor GmbH, Semmelweisstrasse 5, 82152, Planegg, Germany.

The formation of carbonyls and epoxides in e-cigarette (EC) aerosol is possible due to heating of the liquid constituents. However, high background levels of these compounds have inhibited a clear assessment of exposure during use of ECs. An EC containing an e-liquid replaced with 10% of C-labeled propylene glycol and glycerol was used in a controlled use clinical study with 20 EC users. Read More

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Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers.

Fluids Barriers CNS 2021 Jun 22;18(1):28. Epub 2021 Jun 22.

Department of Foundation Medical Studies, Oakland University, William Beaumont School of Medicine586 Pioneer Dr, 460 O'Dowd Hall, Office 415, Rochester, MI, 48309, USA.

Background: The blood-brain barrier (BBB) plays a critical role in protecting the central nervous system (CNS) from blood-borne agents and potentially harmful xenobiotics. Our group's previous data has shown that tobacco smoke (TS) and electronic cigarettes (EC) affect the BBB integrity, increase stroke incidence, and are considered a risk factor for multiple CNS disorders. Metformin was also found to abrogate the adverse effects of TS and EC. Read More

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Electronic Cigarettes: Their Role in the Lives of College Students.

J Pharm Pract 2021 Jun 22:8971900211026841. Epub 2021 Jun 22.

Lachman Consultant, McMurray, PA, USA.

Background: Electronic cigarettes have increased in popularity amongst college-aged adults. Although often advertised as smoking cessation tools, students have taken to them as their primary exposure to nicotine. For many reasons, e-cigarettes are extremely convenient and have become the most common tobacco products among this generation. Read More

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Exposure to fruit-flavoring during adolescence increases nicotine consumption and promotes dose escalation.

Neuropharmacology 2021 Jun 18:108672. Epub 2021 Jun 18.

Department of Psychiatry; Pharmacology Graduate Group; Neuroscience Graduate Group; School of Arts and Sciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104. Electronic address:

The rise of e-cigarette popularity has sparked interest in the role of palatable flavors on nicotine use. Despite growing evidence that sweet flavorants enhance nicotine reward, their influence on nicotine consumption has not been studied extensively. In addition, the impact that flavored nicotine use in adolescence could have on nicotine reward and dependence in adulthood remains unclear. Read More

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Qualitative insights on how adult e-cigarette users describe quantity of e-cigarettes used - PATH Study 2018.

Prev Med Rep 2021 Sep 29;23:101421. Epub 2021 May 29.

Office of Science, Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD, United States.

The purpose of this qualitative study was to gain a deeper understanding of how adult e-cigarette users describe quantity of e-cigarettes used. Data for this analysis came from a qualitative study of U.S. Read More

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September 2021

A content analysis of the tweets of e-cigarette proponents in Australia.

Health Promot J Austr 2021 Jun 18. Epub 2021 Jun 18.

The George Institute for Global Health.

Issue Addressed: Social media sites have become platforms for public discourse on e-cigarettes, providing proponents with an opportunity to disseminate favourable information about the devices. Research examining the information being presented by Australian proponents of e-cigarettes is limited. Accordingly, this study explored the Twitter feeds of Australian proponents of e-cigarettes to determine the nature of the e-cigarette-related content being disseminated. Read More

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Electronic cigarettes and public health awareness: a cross-sectional analysis of Google search inquiries.

Health Educ Res 2021 Jun 18. Epub 2021 Jun 18.

Department of Psychiatry, Oklahoma State University Medical Center, 744 W 9th Street Tulsa, OK 74127, USA.

The number of American adults who use electronic nicotine delivery systems (ENDS) increased by 3 million people in 2018, up 38.3% from 8.1 to 11. Read More

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E-cigarette and dual product use as an emerging health threat to the US military.

Tob Prev Cessat 2021 4;7:43. Epub 2021 Jun 4.

Department of Preventive Medicine & Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, United States.

Introduction: Cigarette and e-cigarette use are threats to the health and readiness of the US military. The study objective was to determine the prevalence and factors associated with e-cigarette, cigarette, and dual use among active duty service members (SMs).

Methods: We used data from the 2015 Health Related Behaviors Survey-a crosssectional survey weighted to represent the US military (n=16699). Read More

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Association between e-cigarette use and parents' report of attention deficit hyperactivity disorder among US youth.

Tob Induc Dis 2021 4;19:44. Epub 2021 Jun 4.

Institute for Global Tobacco Control, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States.

Introduction: There is paucity of literature that evaluates e-cigarette use rates among the youth with attention deficit hyperactivity disorder (ADHD). The aim of this study is to compare the rates of cigarette only, e-cigarette only, dual use, and initiation age of regular use and trying to quit cigarettes or e-cigarettes among the youth with and without ADHD.

Methods: We used Population Assessment of Tobacco and Health (PATH) study Wave 3 (2015-2016) youth data, a nationally representative cross-sectional study in the US. Read More

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What if I Tell You E-Cigarette Users are Inferior? An Investigation of Social Identity Threat in Health Messaging.

Rong Ma Zexin Ma

J Health Commun 2021 Jun 17:1-10. Epub 2021 Jun 17.

Department of Communication, Journalism, and Public Relations, Oakland University, Rochester, Michigan, United States.

Drawing on the literature on social identity threat, this study examined how threatening ecigarette users' identities in a narrative impacts their perceived behavioral control regarding ecigarette use, and how this effect can be moderated by de-emphasizing the story character's user identity. In an experiment, current e-cigarette users (N = 395) read a conversation between the main character (an e-cigarette user) and their friend. Identity threat was manipulated using negative descriptions of e-cigarette users, and identity emphasis was manipulated through the main character's self-description. Read More

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The role of affective urgency and emotion regulation in vaping susceptibility.

Addict Behav Rep 2021 Dec 27;14:100355. Epub 2021 May 27.

Rochester Institute of Technology, Department of Psychology, Health and Addictions Research Center.

Introduction: The prevalence of E-cigarette use is increasing along with concerns about the negative health effects of their use. Understanding the psychological constructs associated with susceptibility to beginning regular e-cigarette use may be helpful for prevention efforts. Factors such as emotion regulation (ER) and impulsivity, specifically urgency, have been significantly correlated with patterns of drug addiction in the past. Read More

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December 2021

Intention to lose weight and use of electronic cigarettes among adolescents.

Prev Med Rep 2021 Sep 18;23:101406. Epub 2021 May 18.

Michael & Susan Dell Center for Healthy Living, University of Texas School of Public Health, Austin Regional Campus, 1616 Guadalupe St., Suite 6.300, Austin TX 78701, USA.

Electronic cigarette use among American adolescents is a major public health concern given the negative health consequences of nicotine in youth. Recent literature has shown that weight control may be one motivation for use in this population. This study examined associations between intention to lose weight and e-cigarette use among adolescents having overweight or obesity from an ethnically diverse sample of Texas youth by gender. Read More

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September 2021

Compositional Differences in the Oral Microbiome of E-cigarette Users.

Front Microbiol 2021 31;12:599664. Epub 2021 May 31.

Pulmonary Critical Care Section, VA San Diego Healthcare System, La Jolla, CA, United States.

Electronic (e)-cigarettes have been advocated as a safer alternative to conventional tobacco cigarettes. However, there is a paucity of data regarding the impact of e-cigarette aerosol deposition on the human oral microbiome, a key component in human health and disease. We aimed to fill this knowledge gap through a comparative analysis of the microbial community profiles from e-cigarette users and healthy controls [non-smokers/non-vapers (NSNV)]. Read More

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Radiological findings of e-cigarette or vaping product use associated lung injury: A systematic review.

Heart Lung 2021 Jun 12;50(5):736-741. Epub 2021 Jun 12.

Melbourne Medical School, University of Melbourne, Melbourne, VIC, 3010, Australia; Department of Radiology, Royal Melbourne Hospital, Melbourne VIC, 3010, Australia.

Introduction: Chest radiology provides an opportunity to better understand the diagnostic characteristics of e-cigarette or vaping product use associated lung injury (EVALI). This systematic review aimed to summarize the radiological findings associated with EVALI reported in the literature.

Methods: This systematic review was conducted in accordance with PRISMA guidelines. Read More

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Association of cigarette and electronic nicotine delivery systems use with internalizing and externalizing problems among US adults: Findings from wave 3 (2015-2016) of the PATH study.

PLoS One 2021 15;16(6):e0253061. Epub 2021 Jun 15.

Institute for Global Tobacco Control, Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

Aims: Electronic Nicotine Delivery System (ENDS) use is increasing among US adults. While existing research has demonstrated higher cigarette smoking rates among people with mental health conditions, there is sparse information on the association between ENDS use and mental health such as internalizing and externalizing problems. The aim of this study was to evaluate associations between internalizing and externalizing problems for cigarette only, ENDS only, and dual users, as well as changes in mental health among those groups. Read More

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Adverse Childhood Experiences and Past 30-Day Cigarette and E-Cigarette Use Among Sexual and Gender Minority College Students.

LGBT Health 2021 Jun 15. Epub 2021 Jun 15.

Department of Health Sciences, California State University, Northridge, Northridge, California, USA.

Sexual and gender minority (SGM) young adults report disproportionately higher rates of tobacco and nicotine product use. This study assessed the role of adverse childhood experiences (ACEs) in nicotine and tobacco product use among SGM young adults. A cross-sectional survey was administered to 11,694 college students (ages 18-29 years) between 2017 and 2018 in California, Minnesota, and Texas. Read More

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Association of vaping with decreased vascular endothelial growth factor expression and decreased microvessel density in cutaneous wound healing tissue in rats.

Wound Repair Regen 2021 Jun 15. Epub 2021 Jun 15.

Boston University School of Medicine, Boston, Massachusetts, USA.

Vaping is suggested to be a risk factor for poor wound healing akin to smoking. However, the molecular and histologic mechanisms underlying this postulation remain unknown. Our study sought to compare molecular and histologic changes in cutaneous flap and non-flap tissue between vaping, smoking and control cohorts. Read More

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Participant Experiences of a Quit Smoking Attempt Through Either Nicotine Replacement Therapy (NRT) Methods or the Use of an E-cigarette.

J Addict Med 2021 Jun 14. Epub 2021 Jun 14.

Academy for Sport and Physical Activity, Health and Wellbeing Department, Sheffield Hallam University, Sheffield, UK (GJ), Lifestyle Exercise and Nutrition Improvement (LENI) Research Group, Department of Nursing and Midwifery, College of Health, Wellbeing and Life Sciences, Sheffield Hallam University, Sheffield, UK (GJ, EM, MK), Addictions, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK and SPECTRUM Research Consortium, UK (LSB).

Objectives: There is a lack of evidence exploring experiences of using e-cigarettes for smoking cessation. The study's main aim was to explore participant experiences of e-cigarettes compared to nicotine replacement therapy (NRT) delivered through stop smoking services.

Methods: Semi-structured, face-to-face, and telephone interviews at 3-month post-quit follow-up in a randomized controlled trial comparing nicotine-containing e-cigarettes, nicotine-free e-cigarettes, and NRT for smoking cessation. Read More

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E-cigarette manufacturers' compliance with clinical trial reporting expectations: a case series of registered trials by Juul Labs.

Tob Control 2021 Jun 14. Epub 2021 Jun 14.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Background: Electronic cigarettes (e-cigarettes) are a frequently debated topic in public health. It is essential that clinical trials examining e-cigarettes are fully and accurately reported, especially given long-standing concerns about tobacco industry research. We assess the reporting of clinical trials sponsored by Juul Labs, the largest e-cigarette company in the USA, against accepted reporting standards. Read More

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'Ice' flavoured e-cigarette use among young adults.

Tob Control 2021 Jun 14. Epub 2021 Jun 14.

Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA.

Background: 'Ice' e-cigarette flavours-marketed as a combination of fruity/sweet and cooling flavours (eg, 'blueberry ice' or 'melon ice')-recently entered the US market. The prevalence and correlates of ice flavoured e-cigarette use in young adults are unknown.

Methods: This cross-sectional study of a Los Angeles, California, USA, cohort analysed data from the past 30-day e-cigarette (current) users (n=344; M (SD)=21. Read More

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Assessing Electronic Nicotine Delivery Systems Use at NCI-Designated Cancer Centers in the Cancer Moonshot-funded Cancer Center Cessation Initiative.

Cancer Prev Res (Phila) 2021 Jun 14. Epub 2021 Jun 14.

Division of Cancer Control and Population Sciences, University of Wisconsin–Madison.

Assessing tobacco product use and delivering tobacco dependence treatment is an essential part of cancer care; however, little is known about electronic nicotine delivery systems (ENDS) or e-cigarette use assessment in cancer treatment settings. Given the importance of tailoring tobacco treatment, it is critical to understand how ENDS use is assessed in the electronic health record (EHR) in cancer care settings. Two questionnaires were completed by tobacco treatment program leads at 42 NCI-Designated Cancer Centers in the Cancer Center Cessation Initiative (January 1 to June 30 and July 1 to December 31, 2019). Read More

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Nicotine/tobacco product use and dependence symptoms among US adolescents and adults: Differences by age, sex, and sexual identity.

Nicotine Tob Res 2021 Jun 14. Epub 2021 Jun 14.

Center for the Study of Drugs, Alcohol, Smoking and Health, Department of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI.

Introduction: Sexual minorities are at increased risk for tobacco use; however, there is heterogeneity in this risk by sociodemographic factors. This study sought to understand if vulnerability to tobacco use among U.S. Read More

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Sensitive Quantification of Nicotine in Bronchoalveolar Lavage Fluid by Acetone Precipitation Combined With Isotope-Dilution Liquid Chromatography-Tandem Mass Spectrometry.

ACS Omega 2021 Jun 25;6(22):13962-13969. Epub 2021 May 25.

Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, U.S. Centers for Disease Control and Prevention (CDC), 4770 Buford Highway, Mail Stop S103-3, Atlanta, Georgia 30341, United States.

The United States experienced an outbreak of e-cigarette, or vaping, product use-associated lung injury (EVALI) that began in August 2019. Patient diagnosis and treatment sometimes involved bronchoscopy and collection of the bronchoalveolar lavage (BAL) fluid. Although this matrix has been useful for understanding some chemical exposures in the lungs, no methods existed for measuring the nicotine content. Read More

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Chronic E-Cigarette Aerosol Inhalation Alters the Immune State of the Lungs and Increases ACE2 Expression, Raising Concern for Altered Response and Susceptibility to SARS-CoV-2.

Front Physiol 2021 31;12:649604. Epub 2021 May 31.

Pulmonary Critical Care Section, VA San Diego Healthcare System, La Jolla, CA, United States.

Conventional smoking is known to both increase susceptibility to infection and drive inflammation within the lungs. Recently, smokers have been found to be at higher risk of developing severe forms of coronavirus disease 2019 (COVID-19). E-cigarette aerosol inhalation (vaping) has been associated with several inflammatory lung disorders, including the recent e-cigarette or vaping product use-associated lung injury (EVALI) epidemic, and recent studies have suggested that vaping alters host susceptibility to pathogens such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Read More

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Identifying message themes to prevent e-cigarette use among youth and young adults.

Prev Med 2021 Jun 10;150:106683. Epub 2021 Jun 10.

Schroeder Institute at Truth Initiative, 900 G Street, NW, Fourth Floor, Washington, DC 20001, USA; Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA; School of Global Public Health, New York University, 665 Broadway, Eleventh Floor, New York, NY 10012, USA. Electronic address:

In 2020, almost 20% of high school students reported current e-cigarette use. Mass media tobacco prevention campaigns are effective for preventing tobacco use among youth and young adults but selecting messages that will have maximum impact on the target audience is a significant challenge for campaign developers. This study describes the method for identification of potential messaging targets for a national anti-vape mass media campaign using criteria proposed by Hornik and Woolf in their health communication framework. Read More

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Cost-Effectiveness Analysis of Smoking Cessation Interventions in the United Kingdom Accounting for Major Neuropsychiatric Adverse Events.

Value Health 2021 Jun 11;24(6):780-788. Epub 2021 Mar 11.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England, UK.

Objectives: Smoking is a leading cause of death worldwide. Cessation aids include varenicline, bupropion, nicotine replacement therapy (NRT), and e-cigarettes at various doses (low, standard and high) and used alone or in combination with each other. Previous cost-effectiveness analyses have not fully accounted for adverse effects nor compared all cessation aids. Read More

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