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Operative and obstetrical outcomes after single-port laparoscopic myomectomy: A retrospective single center analysis of 504 cases.

J Minim Invasive Gynecol 2021 Jun 20. Epub 2021 Jun 20.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea; Department of Surgical Oncology, Sheikh Khalifa Specialty Hospital Ras Al Khaimah, United Arab Emirates.

Study Objective: To analyze the obstetrical and operative outcomes of 504 cases of single-port laparoscopic myomectomy (SPLM).

Design: Single-center retrospective study SETTING: A tertiary university hospital PARTICIPANTS: A total of 502 patients (504 SPLM procedures) who underwent SPLM for symptom relief or growing myomas between October 2009 and April 2020.

Interventions: Data on patient demographics, operative variables (estimated blood loss, hemoglobin decrease, operation time, perioperative complications, and postoperative hospital stay), and obstetrical outcomes (the surgery-to-pregnancy interval and birth-related outcomes) were obtained from medical records and analyzed. Read More

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Cooling Blankets in Hospitalized Patients: Time to Reevaluate.

Am J Med Sci 2021 Jun 20. Epub 2021 Jun 20.

Jane and Dayton Brown Division of Infectious Diseases at the Barbara and Donald Zucker School of Medicine at Northwell/Hofstra University, 400 Community Drive, Manhasset, NY 11030, United States. Electronic address:

Background: The therapeutic benefits and rationale for treating fevers with external cooling methods remain unclear. We aimed to describe the clinical settings in which cooling blankets (CBs) are used.

Design: We conducted a retrospective chart review of CB use in adult patients admitted to our tertiary care center over a one-year period. Read More

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Hyperbaric hyperoxemia as a risk factor for ventilator-acquired pneumonia?

PLoS One 2021 23;16(6):e0253198. Epub 2021 Jun 23.

Intensive Care Unit and Hyperbaric Center, Lille University Hospital, Lille, France.

Objectives: Ventilator-acquired pneumonia (VAP) is the leading cause of serious associated infections in Intensive Care Units (ICU) and is associated with significant morbidity. The use of hyperbaric oxygen therapy (HBOT) in patients on mechanical ventilation may increase exposure to certain risk factors such as hyperoxemia and the need for multiple transfers. The aim of our study was to assess the relationship between HBOT and VAP. Read More

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Ventricular septal defect closure using radial incision of the tricuspid valve for exposure: is it really necessary?

Cardiovasc J Afr 2021 Jun 22;32:1-5. Epub 2021 Jun 22.

Department of Pediatric Cardiac Surgery, Saglik Bilimleri University, Dr Behcet Uz Children's Training and Research Hospital, Izmir, Turkey.

Aim: To evaluate the effects of radial incision of the tricuspid valve in patients who had undergone ventricular septal defect (VSD) closure.

Methods: Overall 173 patients were included in this study between 2012 and 2019. In 44 individuals, a tricuspid valve radial incision (TVRI) was included in the surgical process. Read More

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Contemporary outcomes of continuous-flow biventricular assist devices.

Ann Cardiothorac Surg 2021 May;10(3):311-328

Deutsches Zentrum für Herz Kreislauf Forschung (DZHK) - Standort Berlin/Charité, Berlin, Germany.

Background: Significant right ventricular failure (RVF) complicating left ventricular assist device (LVAD) placement has been reported at 10-30%. Although primarily indicated for left ventricular failure, ventricular assist devices (VADs) have become utilized in a biventricular setup to combat right ventricular failure (RVF) following LVAD implantation. With the advent of continuous-flow LVADs (CF-LVADs) superseding their pulsatile predecessors, the shift towards CF-biventricular assist devices (CF-BiVADs) come with the prospect of improved outcomes over previous pulsatile BiVADs. Read More

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Association between cholera treatment outcome and nutritional status in children aged 2-4 years in Nigeria.

Public Health Action 2021 Jun;11(2):80-84

Operational Centre Brussels, Médecins sans Frontières, Brussels, Belgium.

Setting: Cholera can aggravate or precipitate malnutrition, and children with severe acute malnutrition (SAM) have a higher incidence and longer duration of diarrhoea.

Objective: To describe 1) characteristics of and treatment outcomes in children aged 2-4 years with cholera, 2) the case fatality rate (CFR) in all children treated, and 3) the associations between nutritional status, hydration status, treatment administered and hospital outcomes.

Design: An observational cohort study of children admitted to one cholera treatment centre in Maiduguri, Nigeria, with a focus on children aged 2-4 years. Read More

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Early Outcome of Laparotomy Wounds in Pediatric Patients in TASH, Addis Ababa, Ethiopia: A Six-Months Prospective Study.

Ethiop J Health Sci 2021 Jan;31(1):111-118

Addis Ababa University, Tikur Anbessa Specialized Hospital, Department of Surgery, Zambia St., Addis Ababa, Ethiopia.

Background: Surgical Site Infection (SSI) and wound dehiscence are two early complications of laparotomy causing significant morbidity and mortality. This study was conducted to determine the prevalence and risk factors of SSI and wound dehiscence in pediatric surgical patients.

Methods: We performed a prospective observational study of all pediatric surgical patients who underwent laparotomy at Tikur Anbessa Specialized Hospital, Ethiopia, from December 2017 to May 2018. Read More

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January 2021

Ceftriaxone versus tazobactam/piperacillin and carbapenems in the treatment of aspiration pneumonia: A propensity score matching analysis.

J Infect Chemother 2021 Jun 19. Epub 2021 Jun 19.

Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Aichi, Japan; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan. Electronic address:

Introduction: Aspiration pneumonia (AP) accounts for 5.0-53.2% of hospitalized pneumonia and the treatment commonly used is by broad-spectrum antibiotics to cover anaerobes. Read More

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Tranexamic acid given into wound reduces postoperative drainage, blood loss, and hospital stay in spinal surgeries: a meta-analysis.

J Orthop Surg Res 2021 Jun 22;16(1):401. Epub 2021 Jun 22.

Department of Orthopedics, Peking Union Medical College Hospital, No.1 Shuai Fu Yuan, Wang Fu Jing Street, Beijing, 100730, China.

Background: Although intravenous tranexamic acid administration (ivTXA) has prevailed in clinical antifibrinolytic treatment, whether it increases thromboembolic risks has remained controversial. As a potent alternative to ivTXA, topical use of TXA (tTXA) has been successfully applied to attenuate blood loss in various surgical fields while minimizing systemic exposure to TXA. This meta-analysis was conducted to gather scientific evidence for tTXA efficacy on reducing postoperative drainage, blood loss, and the length of hospital stay in spine surgeries. Read More

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CHARACTERISTICS AND SURVIVAL OF PATIENTS WITH ACUTE TRAUMATIC SPINAL CORD INJURY ABOVE T6 WITH PROLONGED INTENSIVE CARE UNIT STAYS.

World Neurosurg 2021 Jun 19. Epub 2021 Jun 19.

Research Support Unit. Nursing and Healthcare Research Group, Rheumatology and Health Research Group. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña. A Coruña. Spain, As Xubias, 84, 15006. A Coruña, Spain.

Objectives: To characterize patients with an acute traumatic spinal cord injury (ATSCI) above T6 who were admitted to the Intensive Care Unit (ICU) for ≥30 days, as well as their one-year mortality, in comparison with patients admitted for <30 days.

Methods: A retrospective, observational study was performed on 211 patients with an ATSCI above T6 who were admitted to an ICU of a Spanish hospital between 1998-2017. A multivariate logistic regression analysis was performed to determine the relationship between an ICU stay ≥30 days and post-ICU discharge mortality. Read More

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Psychiatric Outcomes of Childhood Maltreatment: A Retrospective Chart Review from a Children's Psychiatric Inpatient Program.

Child Psychiatry Hum Dev 2021 Jun 22. Epub 2021 Jun 22.

Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.

Childhood maltreatment is linked to deleterious outcomes, whereby post-traumatic stress disorder (PTSD) has been identified as one of the most debilitating. This retrospective chart review examined whether self-reported affective measures (anxiety, depression, trauma), type of maltreatment (sexual, physical, emotional/verbal abuses), and demographics predicted a diagnosis of anxiety or PTSD among 169 children in a psychiatric inpatient hospital. Secondly, this study identified significant predictors of a PTSD diagnosis. Read More

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Predictors of poor outcomes among patients of acute methanol intoxication with particular reference to Sequential Organ Failure Assessment (SOFA) score.

Environ Sci Pollut Res Int 2021 Jun 22. Epub 2021 Jun 22.

Emergency Medicine Department, King Fahad Medical City (KFMC), Riyadh, Saudi Arabia.

Methanol intoxication is a global problem with serious morbidities and mortalities. Apart from the lifelong disabilities experienced by methanol intoxication survivors, mortality rates of up to 44% of exposed patients have been reported. The aim of the current study was to outline the early findings that could be utilized as effective in-hospital outcome predictors among cases of methanol exposure. Read More

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TRANSCATHETER VERSUS SURGICAL AORTIC VALVE REPLACEMENT: FIRST EXPERIENCE WITH A NEW TAVI SYSTEM.

Wiad Lek 2021 ;74(4):856-863

UKRAINIAN CHILDREN'S CARDIAC CENTER, KYIV, UKRAINE.

Objective: The aim: to reveal early results after transapical TAVI with a new self-manufactured XPand system, comparing them with SAVR and common transfemoral TAVI outcomes.

Patients And Methods: Materials and methods: Eighty-four patients (mean age 79,5±10,2 years) with severe aortic stenosis were operated on from January 2016 to February 2019. Nine patients had undergone the TAVI (two with transfemoral access route and seven with transapical, using the XPand system). Read More

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Évaluation médico-economique de l’impact de mesures d’adaptation au virage de la chirurgie robot-assistée en urologie.

Prog Urol 2021 Jun 18. Epub 2021 Jun 18.

Service d'Urologie, Andrologie, Transplantation Rénale, Hôpital Pasteur 2, CHU de Nice.

Introduction: The development of robot-assisted urological surgery is held back by the lack of robust medico-economic analyses and their heterogeneity. We conducted a medico-economic study to evaluate the implementation of measures to optimize the transition to robotic surgery.

Method: We carried out a single-center, controlled study from the point of view of the public healthcare establishment for 4 years. Read More

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Clinical outcomes of levosimendan versus dobutamine in patients with acute decompensated heart failure with reduced ejection fraction and impaired renal function.

Indian Heart J 2021 May-Jun;73(3):372-375. Epub 2021 Feb 17.

Lisie Hospital in Cochin, Kerala, India. Electronic address:

To assess the clinical outcomes of levosimendan and dobutamine in patients with acute decompensated heart failure with reduced ejection fraction and impaired renal function in Indian scenario. Cardiac, renal, electrolytes and hepatic parameters as well as the clinical outcomes were assessed. Levosimendan and dobutamine improved ejection fraction significantly. Read More

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February 2021

Risk factors associated with mechanical ventilation, autonomic nervous dysfunction and physical outcome in Vietnamese adults with tetanus.

Trop Med Health 2021 Jun 21;49(1):50. Epub 2021 Jun 21.

Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.

Background: Tetanus remains common in many low- and middle-income countries, but as critical care services improve, mortality from tetanus is improving. Nevertheless, patients develop severe syndromes associated with autonomic nervous system disturbance (ANSD) and the requirement for mechanical ventilation (MV). Understanding factors associated with worse outcome in such settings is important to direct interventions. Read More

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Analysis of Later Stage Morbidity and Mortality after Pancreatic Surgery Because of Abdominal Trauma.

Surg Infect (Larchmt) 2021 Jun 21. Epub 2021 Jun 21.

Department of General Surgery, Jinling Hospital, Jiangsu Nanjing, China.

Pancreatic trauma surgery is a complicated surgical procedure for severe pancreatic injuries, accompanied by a high incidence of complications and mortality. This study was designed to explore the long-term prognosis of pancreatic surgery because of abdominal trauma. The clinical data of 103 patients who were admitted to Jinling Hospital between August 2012 and August 2019 who had pancreatic trauma surgery were analyzed retrospectively. Read More

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Epidural Filling with Crystal-colloid Solution for Post Accidental Dural Puncture Headache: A Case Series.

Clin Invest Med 2021 06 14;44(2):E44-47. Epub 2021 Jun 14.

Department of Anesthesiology, Chongqing Health Center for Women and Children, Chongqing, China.

Purpose: Post dural puncture headache (PDPH) is a common anesthetic complication caused by expected spinal puncture or accidental dural puncture during intraspinal anesthesia operation. The purpose of this study was to retrospectively analyze the clinical features and outcomes of parturients with accidental dural punctures (ADP).

Methods: (All cesarean sections at the Chongqing Health Center for Women and Children (Chongqing, China) carried out under neuraxial anesthesia from January 1, 2017 to December 31, 2018 were reviewed and data from 20 parturients with ADP were collected and analyzed. Read More

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Systematic review of Meckel's diverticulum in pregnancy.

ANZ J Surg 2021 Jun 21. Epub 2021 Jun 21.

Western Sussex Hospitals NHS Trust, Chichester, UK.

Introduction: Meckel's diverticulum (MD) is the most common congenital malformation in the gastrointestinal tract. Limited up-to-date evidence is available regarding MD in pregnancy. We aim to review the available pertinent literature to help support clinical decision making and patient management in the future. Read More

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Perioperative Outcomes of Robot-Assisted Radical Cystectomy with Intracorporeal Versus Extracorporeal Urinary Diversion.

Ann Surg Oncol 2021 Jun 21. Epub 2021 Jun 21.

S.H. Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.

Purpose: This study was designed to investigate and compare the perioperative outcomes of intracorporeal urinary diversion (ICUD) versus extracorporeal urinary diversion (ECUD) following robotic-assisted radical cystectomy (RARC) in patients with localized bladder cancer from the Asian Robot-Assisted Radical Cystectomy (RARC) Consortium.

Methods: The Asian RARC registry was a multicenter registry involving nine centers in Asia. Consecutive patients who underwent RARC were included. Read More

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Lessons Learned in 11 Years of Experience With Open Abdomen Treatment With Negative-Pressure Therapy for Various Abdominal Emergencies.

Front Surg 2021 4;8:632929. Epub 2021 Jun 4.

Medical University Innsbruck, Innsbruck, Austria.

Open abdomen (OA) treatment with negative-pressure therapy (NPT) was initiated for perforated diverticulitis and subsequently extended to other abdominal emergencies. The aim of this retrospective study was to analyze the indications, procedures, duration of NPT, and the outcomes of all our patients. All consecutive patients treated with intra-abdominal NPT from January 1, 2008 to December 31, 2018 were retrospectively analyzed. Read More

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Comparison of Crystallized Phenol Application and the Karydakis Flap Technique in the Treatment of Sacrococcygeally Localized Pilonidal Sinus Disease.

Cureus 2021 May 14;13(5):e15030. Epub 2021 May 14.

General Surgery, Ankara City Hospital, Ankara, TUR.

Objective To evaluate crystallized phenol application and the Karydakis flap procedure in terms of treatment success, postoperative complications, and recurrence in the treatment of pilonidal sinus disease (PSD). Materials and methods The study included patients who underwent the Karydakis flap procedure and crystallized phenol application with the diagnosis of PSD in our clinic between June 2016 and January 2019. Age, gender, preoperative body mass index (BMI), sinus number, number of crystallized phenol administrations, postoperative length of hospital stay, postoperative complications, and recurrence rates were compared between the Karydakis and crystallized phenol groups. Read More

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Implication of excessive length of stay of asthma patient with heterogenous status attributed to air pollution.

J Environ Health Sci Eng 2021 Jun 7;19(1):95-106. Epub 2021 Jan 7.

West China Hospital, Sichuan University, Guo Xue Xiang No. 37, Chengdu, Sichuan 610041 People's Republic of China.

Objective: Air pollution has potential risk on asthma patients, further prolongs the length of stay. However, it is unclear that the impact of air pollution on excessive length of stay (ELoS) of heterogeneous asthma patients. In this study, we proposed a K-Nearest Neighbor (KNN) embedded approach incorporating with patient status to analyze the impact of short-term air pollution on the ELoS of asthma patients. Read More

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The effect of EBN combined with integrated hierarchical accountability nursing on patients with severe pneumonia.

Am J Transl Res 2021 15;13(5):5610-5616. Epub 2021 May 15.

Nursing Department, Hebei PetroChina Central Hospital Langfang, Hebei, China.

Objective: To explore the effects of evidence-based nursing (EBN) combined with integrated hierarchical accountability nursing on patients with severe pneumonia (SP).

Methods: 72 SP patients admitted to our hospital from March 2019 to March 2020 were recruited as the study cohort and randomly divided into control group (36 patients) or research group (36 patients). The control group underwent conventional nursing, and the research group underwent EBN combined with integrated hierarchical accountability nursing plus. Read More

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Efficacy of montmorillonite and vitamin AD combined with zinc preparation in children with diarrheal disease and its effect on inflammatory factors.

Am J Transl Res 2021 15;13(5):5428-5435. Epub 2021 May 15.

Department of Child Health Care, Anhui Children's Hospital Hefei 230001, Anhui Province, China.

Objective: To investigate the effect of montmorillonite and vitamin AD combined with zinc preparation in children with diarrheal disease and its effect on inflammatory factors.

Methods: A total of 156 children with diarrheal diseases admitted to our hospital from January 2018 to January 2020 were enrolled and divided into two groups (n=78 for each) using random number table. The control group (CG) was treated with montmorillonite, and the observation group (OG) was additionally treated with vitamin AD and zinc. Read More

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The effect and prognosis of combinative implantation by autologous-fat granule and prosthesis for breast reconstruction after radical mastectomy.

Am J Transl Res 2021 15;13(5):5256-5263. Epub 2021 May 15.

Department of Stomatology, Affiliated Kaikou Hospital of Xiangya Medical College, Central South University Haikou 570204, Hainan, China.

Objectives: In this study, we analyzed the effect and prognosis of combinative implantation of autologous-fat granule and prosthesis for breast reconstruction after radical mastectomy.

Methods: 73 cases of breast cancer patients hospitalized from March 2015 to March 2017 were chosen and separated into observation group (n=41) and control group (n=32) on the basis of the surgical methods. Both the two groups underwent modified radical mastectomy. Read More

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Analysis on the application value of goal-directed fluid therapy in patients undergoing laparoscopy-assisted radical gastrectomy with fast-track anesthesia.

Am J Transl Res 2021 15;13(5):5174-5182. Epub 2021 May 15.

Department of Anesthesiology, Zhuji People's Hospital Zhuji 311800, Zhejiang Province, China.

Objective: To explore the application value of goal-directed fluid therapy (GDFT) in patients undergoing laparoscopy-assisted radical gastrectomy with fast-track anesthesia.

Methods: From December 2016 to December 2019, 74 patients who underwent laparoscopy-assisted radical gastrectomy under the concept of enhanced recovery after surgery (ERAS) in gastrointestinal Surgery department of Tongling People's Hospital were selected as research participants. They were divided into two groups: the routine group (patients were treated with conventional fluids) (n=37) and the GDFT group (patients were treated with GDFT) (n=37). Read More

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Efficacy of intrauterine Bakri balloon tamponade combined with ascending uterine artery ligation on postpartum hemorrhage.

Am J Transl Res 2021 15;13(5):4995-5002. Epub 2021 May 15.

Department of Obstetrics, Tai'an City Central Hospital Tai'an 271000, Shandong Province, China.

Objective: To observe the efficacy of intrauterine Bakri balloon tamponade (IBBT) combined with ascending uterine artery ligation (AUAL) in the treatment of postpartum hemorrhage (PPH) due to uterine inertia after cesarean section.

Methods: A total of 92 patients with PPH due to uterine inertia after cesarean section were divided into a study group (n=46) and a control group (n=46) in accordance with the random number table. The control group was treated with IBBT alone, while the study group was treated with IBBT combined with AUAL. Read More

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Paternal Leave and Father-Infant Bonding: Findings From the Population-Based Cohort Study DREAM.

Front Psychol 2021 4;12:668028. Epub 2021 Jun 4.

Institute and Policlinic of Occupational and Social Medicine, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

Father-infant bonding is important for child development. Yet, in contrast to mother-infant bonding, little is known about factors that might facilitate father-infant bonding. With new generations of fathers being more involved in childcare, this study aims to examine the impact of paternal leave duration on father-infant bonding, and whether this relation is mediated by the amount of time fathers actively spend on childcare. Read More

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Airway Pressure Release Ventilation Mode Improves Circulatory and Respiratory Function in Patients After Cardiopulmonary Bypass, a Randomized Trial.

Front Physiol 2021 3;12:684927. Epub 2021 Jun 3.

Department of Respiratory and Critical Care, Regional Medical Center for National Institute of Respiratory Diseases, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Importance: Postoperative pulmonary complications and cardiovascular complications are major causes of morbidity, mortality, and resource utilization in cardiac surgery patients.

Objectives: To investigate the effects of airway pressure release ventilation (APRV) on respiration and hemodynamics in post cardiac surgery patients.

Main Outcomes And Measures: A single-center randomized control trial was performed. Read More

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