11,075 results match your criteria duration sensory


Single dose perioperative intrathecal ketamine as an adjuvant to intrathecal bupivacaine: A systematic review and meta-analysis of adult human randomized controlled trials.

J Clin Anesth 2021 May 5;73:110331. Epub 2021 May 5.

Zucker School of Medicine at Hofstra/Northwell, Department of Anesthesiology, Northwell Health, New Hyde Park, NY, United States of America.

Study Objective: To identify whether adding intrathecal ketamine to intrathecal bupivacaine prolongs the time to first analgesic request in adult humans.

Design: A meta-analysis of randomized controlled trials in humans.

Setting: The majority of data was obtained in an operating room and postoperative recovery area. Read More

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Percutaneous Cryoneurolysis for Acute Pain Management: Current Status and Future Prospects.

Expert Rev Med Devices 2021 May 7. Epub 2021 May 7.

University of California San Diego, Department of Anesthesiology, San Diego, California.

Introduction: Conventional nerve blocks utilize local anesthetic drugs to provide pain relief for hours or days following surgery or trauma. However, postoperative and trauma pain can last weeks or months. Ultrasound-guided percutaneous cryoneurolysis is an anesthetic modality that offers substantially longer pain relief compared to local anesthetic-based nerve blocks. Read More

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Unattended Emotional Prosody Affects Visual Processing of Facial Expressions in Mandarin-Speaking Chinese: A Comparison With English-Speaking Canadians.

J Cross Cult Psychol 2021 Apr 15;52(3):275-294. Epub 2021 Feb 15.

McGill University, Montréal, QC, Canada.

Emotional cues from different modalities have to be integrated during communication, a process that can be shaped by an individual's cultural background. We explored this issue in 25 Chinese participants by examining how listening to emotional prosody in Mandarin influenced participants' gazes at emotional faces in a modified visual search task. We also conducted a cross-cultural comparison between data of this study and that of our previous work in English-speaking Canadians using analogous methodology. Read More

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Patterns of whole-body muscle activations following vertical perturbations during standing and walking.

J Neuroeng Rehabil 2021 May 6;18(1):75. Epub 2021 May 6.

Center of Advanced Technologies in Rehabilitation, Sheba Medical Center, Ramat Gan, Israel.

Background: Falls commonly occur due to losses of balance associated with vertical body movements (e.g. reacting to uneven ground, street curbs). Read More

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Mealtime behaviours of young children with sensory food aversions: An observational study.

Aust Occup Ther J 2021 May 6. Epub 2021 May 6.

Department of Occupational Therapy, University of Pittsburgh, Pittsburgh, PA, USA.

Introduction: Children with sensory food aversions (SFAs) are at risk for nutritional problems and occupational dysfunction during daily meals. To facilitate optimal occupational performance for children with SFAs, it is critical that clinicians understand child behaviour and caregiver strategy use to manage child behaviour during meals. The purpose of this paper is to examine the reliability of a novel coding scheme, the Behavioural Mealtime Coding System (BMCS) and identify associations among child acceptance of preferred and targeted foods, child food exploration and caregiver use of strategies to manage child behaviour. Read More

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Dissociating the effects of delay and interference on dog (Canis familiaris) working memory.

Anim Cogn 2021 May 5. Epub 2021 May 5.

Department of Psychological Sciences, Auburn University, Auburn, AL, USA.

Delayed matching-to-sample (dMTS) is commonly used to study working memory (WM) processes in non-humans. Previous procedures for studying dog WM, including versions of the dMTS, did not separate the impact of delay and interference on memory performance. These studies were also limited to auditory and spatial stimuli, neglecting dogs' dominant sensory modality (i. Read More

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Input-independent homeostasis of developing thalamocortical activity.

eNeuro 2021 May 4. Epub 2021 May 4.

Department of Pharmacology and Physiology, The George Washington University

The isocortex of all mammals studied to date shows a progressive increase in the amount and continuity of background activity during early development. In humans the transition from a discontinuous (mostly silent, intermittently bursting) cortex to one that is continuously active is complete soon after birth and is a critical prognostic indicator. In the visual cortex of rodents this switch from discontinuous to continuous background activity occurs during the two days before eye-opening, driven by activity changes in relay thalamus. Read More

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Long-Term Trigeminal Nerve Stimulation as a Treatment for Ocular Pain.

Neuromodulation 2021 May 4. Epub 2021 May 4.

Surgical and Research Services, Miami Veterans Affairs Medical Center, Miami, Florida, USA.

Objectives: Ocular pain symptoms (e.g., hypersensitivity to light and wind, "burning" sensations) can be debilitating and difficult to treat. Read More

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Schooling in Tadpoles as a Way to Assess Their Neural Development.

Cold Spring Harb Protoc 2021 May 3;2021(5):pdb.prot106906. Epub 2021 May 3.

Department of Neuroscience, Brown University, Providence, Rhode Island 02912, USA;

Escape behaviors, orienting reflexes, and social behaviors in tadpoles have been well-documented in the literature. Schooling behavior experiments allow for the observation of tadpole social interactions and in the past have been used to characterize behavioral deficits in models of neurodevelopmental disorders. Unlike other species of frogs, tadpoles show polarized schooling. Read More

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Dexmedetomidine versus sufentanil as adjuvants to bupivacaine for brachial plexus block during upper extremity surgery: a randomized clinical trial.

Braz J Anesthesiol 2021 Apr 28. Epub 2021 Apr 28.

AJA University of Medical Sciences, Department of Anesthesiology, Tehran, Iran. Electronic address:

Background: Brachial plexus block (BPB) has been accepted as a reliable alternative for general anesthesia in upper limb surgeries. Adding adjuvant drugs like dexmedetomidine and sufentanil has been shown to have clinical and pharmacologic advantages. In this randomized parallel clinical trial, we aim to compare the effects of these two adjuvants for bupivacaine in BPB. Read More

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The Effect of Dexmedetomidine in Combination with Bupivacaine on Sensory and Motor Block Time and Pain Score in Supraclavicular Block.

Pain Res Manag 2021 10;2021:8858312. Epub 2021 Apr 10.

Department of Anesthesiology, Urmia Imam Khomeini Hospital, Urmia University of Medical Science, Urmia, Iran.

Background: Brachial plexus block is frequently recommended for upper limb surgeries. Many drugs have been used as adjuvants to prolong the duration of the block. This study aimed to assess the effect of dexmedetomidine with bupivacaine combination and only bupivacaine on sensory and motor block duration time, pain score, and hemodynamic variations in the supraclavicular block in upper extremity orthopedic surgery. Read More

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Effects of Oro-Sensory Exposure on Satiation and Underlying Neurophysiological Mechanisms-What Do We Know So Far?

Nutrients 2021 Apr 21;13(5). Epub 2021 Apr 21.

Division of Human Nutrition and Health, Wageningen University & Research, P.O. Box 17, NL-6700 AA Wageningen, The Netherlands.

The mouth is the first part of the gastrointestinal tract. During mastication sensory signals from the mouth, so-called oro-sensory exposure, elicit physiological signals that affect satiation and food intake. It has been established that a longer duration of oro-sensory exposure leads to earlier satiation. Read More

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Acute inflammatory demyelinating polyneuropathy or Guillain-Barré syndrome associated with COVID-19: a case report.

J Med Case Rep 2021 Apr 28;15(1):219. Epub 2021 Apr 28.

Intensive Care Unit, Phelps Hospital Northwell Health, Tarrytown, NY, USA.

Background: Coronavirus disease 2019 (COVID-19) is a global pandemic. The disease, typically characterized by bilateral pulmonary infiltrates and profound elevation of inflammatory markers, can range in severity from mild or asymptomatic illness to a lethal cytokine storm and respiratory failure. A number of recognized complications of COVID-19 infection are described in the literature. Read More

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The role of somatosensation in automatic visuo-motor control: a comparison of congenital and acquired sensory loss.

Exp Brain Res 2021 Apr 28. Epub 2021 Apr 28.

Department of Neurobiology, The University of Chicago, Chicago, IL, USA.

Studies of chronically deafferented participants have illuminated how regaining some motor control after adult-onset loss of proprioceptive and touch input depends heavily on cognitive control. In this study we contrasted the performance of one such man, IW, with KS, a woman born without any somatosensory fibres. We postulated that her life-long absence of proprioception and touch might have allowed her to automate some simple visually-guided actions, something IW appears unable to achieve. Read More

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Effect of combined versus sequential injection of 2% lidocaine and 0.5% bupivacaine on the onset and duration of supraclavicular brachial plexus block: A double blinded randomised controlled trial.

J Clin Anesth 2021 Apr 24;72:110313. Epub 2021 Apr 24.

Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, India.

Objective: To assess whether sequential (one after the other with a delay of 120 s) or combined (freshly prepared mixture) administration of 2% lidocaine and 0.5% bupivacaine in supraclavicular brachial plexus block (SCBPB) provides faster onset and prolonged duration of block.

Design: Randomised controlled double blinded study. Read More

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Transient Vestibular Symptoms Preceding Posterior Circulation Stroke: A Prospective Multicenter Study.

Stroke 2021 Apr 27:STROKEAHA120032488. Epub 2021 Apr 27.

Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine, Biomedical Research Institute, Busan, South Korea (S.-Y.C., K-D.C.).

Background And Purpose: The recognition of clinical features of transient vestibular symptoms (TVSs) preceding posterior circulation stroke (PCOS) would be informative to discriminate dizziness/vertigo due to vertebrobasilar transient ischemic attack from the acute transient vestibular syndrome. We sought to determine the prevalence and characteristics of TVSs preceding PCOS.

Methods: We performed a prospective multicenter observational study that had recruited 447 patients with PCOS from referral-based 4 university hospitals in Korea. Read More

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The impact of symptoms on daily life as perceived by patients with Charcot-Marie-Tooth type 1A disease.

Neurol Sci 2021 Apr 26. Epub 2021 Apr 26.

Department of Neuroscience, Reproductive and Odontostomatological Science, University of Naples "Federico II", Via Sergio Pansini, 5, 80131, Naples, Italy.

Introduction: In Charcot-Marie-Tooth type 1A (CMT1A) patients, daily life is mainly influenced by mobility and ambulation dysfunctions. The aim of our work was to evaluate the perception of disturbances that mostly impact on daily life in CMT1A patients and its difference on the basis of age, gender, disability, and quality of life.

Methods: Forty-one CMT1A patients underwent neurological assessment focused on establishing clinical disability through the Charcot-Marie-Tooth Neuropathy Score (CMTNS) and quality of life through the Short Form-36 (SF-36) questionnaire. Read More

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Foot and ankle somatosensory deficits in children with cerebral palsy: A pilot study.

J Pediatr Rehabil Med 2021 Apr 23. Epub 2021 Apr 23.

Department of Kinesiology, University of Delaware, Newark, DE, USA.

Purpose: To investigate foot and ankle somatosensory function in children with cerebral palsy (CP).

Methods: Ten children with spastic diplegia (age 15 ± 5 y; GMFCS I-III) and 11 typically developing (TD) peers (age 15 ± 10 y) participated in the study. Light touch pressure and two-point discrimination were assessed on the plantar side of the foot by using a monofilament kit and an aesthesiometer, respectively. Read More

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Technical considerations and outcome of free functioning gracilis muscle transfer for finger flexion in patients with Volkmann's Ischemic Contracture.

Injury 2021 Apr 20. Epub 2021 Apr 20.

Division of Plastic Surgery, Hand Surgery, Reconstructive Microsurgery and Burns, Ganga Hospital, 313, Mettupalayam Road, Coimbatore, Tamil Nadu, India- 641043. Electronic address:

Introduction: Severe Volkmann's Ischemic Contracture (VIC) is a reconstructive challenge for the surgeon because of the loss of entire flexor muscle mass and lack of powerful wrist extensors for restoration of finger flexion. In such cases, free functioning muscle transfer (FFMT) using gracilis is our choice. We herein summarize the technical considerations to achieve a successful outcome and report functional outcome achieved in our series. Read More

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Nalbuphine for spinal anesthesia : A Systematic Review and meta-analysis.

Pain Pract 2021 Apr 22. Epub 2021 Apr 22.

Department of Anesthesiology, Huai'an Hospital, Xuzhou Medical University, Jiangsu Province, Huai'an, 223002, China.

Purpose: Various adjuvants for prolongation of intraoperative and postoperative analgesia have been clinically studied, but the safety and efficiency of nalbuphine as an adjuvant to local anesthetics in spinal anesthesia remains unconfirmed. Therefore, we conducted a meta-analysis about the effect of nalbuphine as an adjuvant to local anesthetics in spinal anesthesia in regard to time of onset of sensory blockade and motor blockade,duration of motor blockade, two-segment sensory regression time, the duration of analgesia, and incidence of side effects to provide a reliable basis for clinical application.

Methods: Databases including PubMed, Cochrane, EMBASE, Web of Science, CNKI, CBM, WanFang database and Viper database were searched for eligible studies. Read More

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Dalbavancin Efficacy and Impact on Hospital Length-of-Stay and Treatment Costs in Different Gram-Positive Bacterial Infections.

Clin Drug Investig 2021 Apr 21. Epub 2021 Apr 21.

Department of Biomedical Sciences and Human Oncology, Clinic of Infectious Diseases, University of Bari, Bari, Italy.

Background And Objectives: The study aimed to evaluate the impact of dalbavancin therapy on both hospital length-of-stay (LOS) and treatment-related costs, as well as to describe the clinical outcome, in a retrospective cohort of patients with diverse Gram-positive bacterial infections, hospitalized in different specialty Units.

Methods: From July 2017 to July 2019, clinical and sociodemographic data were collected for all hospitalized patients switched to dalbavancin for the treatment of Gram-positive infections. LOS and treatment-related costs were assessed and compared to a hypothetical scenario where the initial standard antimicrobial therapy would have been administered in hospital for the same duration as dalbavancin. Read More

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Sensory Function and Psychological Factors in Children With Complex Regional Pain Syndrome Type 1.

J Child Neurol 2021 Apr 21:8830738211007685. Epub 2021 Apr 21.

Applied Psychology, Western University, London, Ontario, Canada.

Objective: To assess thermal-sensory thresholds and psychosocial factors in children with Complex Regional Pain Syndrome Type 1 (CRPS-I) compared to healthy children.

Methods: We conducted quantitative sensory testing on 34 children with CRPS-I and 56 pain-free children. Warm, cool, heat, and cold stimuli were applied to the forearm. Read More

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Phasic Off responses of auditory cortex underlie perception of sound duration.

Cell Rep 2021 Apr;35(3):109003

School of Biomedical Engineering, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Key Laboratory of Mental Health of the Ministry of Education, Guangdong Provincial Key Laboratory of Shock and Microcirculation, Southern Medical University, Guangzhou 510515, China; Department of Anesthesiology, Zhujiang Hospital of Southern Medical University, Guangzhou 510220, China. Electronic address:

It has been proposed that sound information is separately streamed into onset and offset pathways for parallel processing. However, how offset responses contribute to auditory perception remains unclear. Here, loose-patch and whole-cell recordings in awake mouse primary auditory cortex (A1) reveal that a subset of pyramidal neurons exhibit a transient "Off" response, with its onset tightly time-locked to the sound termination and its frequency tuning similar to that of the transient "On" response. Read More

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Chronic inflammatory demyelinating polyneuropathy with hypertrophic nerves.

J Peripher Nerv Syst 2021 Apr 21. Epub 2021 Apr 21.

Department of Neurology, Neurocenter of Southern Switzerland, Lugano, Switzerland.

We describe the distinctive features (with images and video) of a case of chronic inflammatory demyelinating polyneuropathy (CIDP) with giant nerves. The main clinical findings were insidious onset, gait ataxia and sensory symptoms. Electrodiagnostic studies showed very slow nerve conduction velocities, multiple conduction blocks, distal CMAP duration increase and absence of F-waves. Read More

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Prospective Randomized Control Trial Comparing Effect of Dexamethasone Versus Fentanyl as Adjuvants to Intrathecal Bupivacaine for Orthopedic Surgery.

Cureus 2021 Mar 17;13(3):e13949. Epub 2021 Mar 17.

Orthopedics, Medanta Hospital, Gurgaon, IND.

Introduction Spinal anesthesia is the most consistent block for lower limb orthopedic surgeries. We conducted this randomized prospective study to evaluate comparative efficacy of intrathecal dexamethasone with fentanyl and normal saline as adjuvants to hyperbaric bupivacaine in spinal anesthesia administered to patients scheduled for lower limb orthopedic surgery. Materials and methods 105 patients scheduled for lower limb orthopedic surgeries under spinal anesthesia were included in this clinical trial. Read More

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Circadian fluctuations in glucocorticoid level predict perceptual discrimination sensitivity.

iScience 2021 Apr 21;24(4):102345. Epub 2021 Mar 21.

Department of Psychology, University of Lübeck, 23562 Lübeck, Germany.

Slow neurobiological rhythms, such as the circadian secretion of glucocorticoid (GC) hormones, modulate a variety of body functions. Whether and how endocrine fluctuations also exert an influence on perceptual abilities is largely uncharted. Here, we show that phasic increases in GC availability prove beneficial to auditory discrimination. Read More

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Flavor Characteristics of Ganpu Tea Formed During the Sun-Drying Processing and Its Antidepressant-Like Effects.

Front Nutr 2021 24;8:647537. Epub 2021 Mar 24.

Guangdong Key Laboratory for Innovative Development and Utilization of Forest Plant Germplasm, College of Forestry and Landscape Architecture, South China Agricultural University, Guangzhou, China.

Ganpu tea is a novel type of tea beverage with unique and pleasant flavor that encases Pu-erh tea leaves within an intact mandarin peel. However, to date, no holistic and detail studies on its chemical composition and biological activities have been reported yet. In the present study, by applying UPLC-Q-TOF and UPLC-MS technology, we systematically identified and analyzed 104 water-soluble compounds of Ganpu tea and their variation trend during the sun-drying processing. Read More

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Effect of the Stimulus Duration on the Adaptation of the Optokinetic Afternystagmus.

Front Neurol 2021 31;12:518133. Epub 2021 Mar 31.

Department of Neurology, University Hospital Zurich, Zurich, Switzerland.

Observing a rotating visual pattern covering a large portion of the visual field induces optokinetic nystagmus (OKN). If the lights are suddenly switched off, optokinetic afternystagmus (OKAN) occurs. OKAN is hypothesized to originate in the velocity storage mechanism (VSM), a central processing network involved in multi-sensory integration. Read More

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Sounds Healthy: Modelling sound-evoked consumer food choice through visual attention.

Appetite 2021 Apr 16;164:105264. Epub 2021 Apr 16.

Food Quality Perception & Society Team, iSENSE Lab, Department of Food Science, Aarhus University, Aarhus, Denmark; Sino-Danish College (SDC), University of Chinese Academy of Sciences, Beijing, China.

Food choice is a multifaceted construct that is not solely guided by our internal incentives. In fact, sensory scientist, consumer psychologists, and marketers have demonstrated that external ambient cues, including background music, can influence myriads of subconscious consumer behaviors, effectively leading to increased sales of food and beverages. However, the vast majority of literature in on this topic has thus far been confined to monocultural field studies in which the underlying mechanisms of food choice are unexplored. Read More

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A mobile app that uses neurofeedback and multi-sensory learning methods improves reading abilities in dyslexia: A pilot study.

Appl Neuropsychol Child 2021 Apr 16:1-11. Epub 2021 Apr 16.

Department of Electrical and Computer Engineering, University of Rochester, Rochester, NY, USA.

Reading comprehension is difficult to improve for children with dyslexia because of the continuing demands of orthographic decoding in combination with limited working memory capacity. Children with dyslexia get special education that improves spelling, phonemic and vocabulary awareness, however the latest research indicated that special education does not improve reading comprehension. With the aim of improving reading comprehension, reading speed and all other reading abilities of children with dyslexia, Auto Train Brain that is a novel mobile app using neurofeedback and multi-sensory learning methods was developed. Read More

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