Orphanet J Rare Dis 2021 Apr 29;16(1):191. Epub 2021 Apr 29.
Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Background: Tenosynovial giant cell tumor (TGCT) is a rare, locally aggressive neoplasm arising from the synovium of joints, bursae, and tendon sheaths affecting small and large joints. It represents a wide spectrum ranging from minimally symptomatic to massively debilitating. Most findings to date are mainly from small, retrospective case series, and thus the morbidity and actual impact of this rare disease remain to be elucidated. Read More