14 results match your criteria drcc

  • Page 1 of 1

Diabetes-related chronic complications in Brazilian adolescents with type 1 diabetes. A multicenter cross-sectional study.

Diabetes Res Clin Pract 2021 Jun 4;177:108895. Epub 2021 Jun 4.

Medical Doctor Program, University of São Paulo- School of Dentistry, Bauru, São Paulo, Brazil.

Aims: To investigate the prevalence of diabetes-related chronic complications (DRCCs) and its associated factors in Brazilian adolescents with type 1 diabetes (T1D).

Methods: This nationwide study was conducted in 14 public clinics in 10 cities, with 1,760 patients, 367 adolescents, with 328 eligible for this study. Evaluated DRCCs were retinopathy (DR), chronic kidney disease (CKD), peripheral neuropathy (DPN) and cardiovascular autonomic neuropathy (CAN). Read More

View Article and Full-Text PDF

Donor Recipient Chimeric Cells Induce Chimerism and Extend Survival of Vascularized Composite Allografts.

Arch Immunol Ther Exp (Warsz) 2021 May 10;69(1):13. Epub 2021 May 10.

Department of Orthopaedics, University of Illinois At Chicago, Molecular Biology Research Building, 900 S. Ashland Ave. Room# 3356, Chicago, IL, 60607, USA.

This study evaluated the efficacy of donor recipient chimeric cell (DRCC) therapy created by fusion of donor and recipient derived bone marrow cells (BMC) in chimerism and tolerance induction in a rat vascularized composite allograft (VCA) model. Twenty-four VCA (groin flaps) from MHC-mismatched ACI (RT1) donors were transplanted to Lewis (RT1) recipients. Rats were randomly divided into (n = 6/group): Group 1-untreated controls, Groups 2-7-day immunosuppression controls, Group 3-DRCC, and Group 4-DRCC with 7-day anti-αβTCR monoclonal antibody and cyclosporine A protocol. Read More

View Article and Full-Text PDF

Development of Donor Recipient Chimeric Cells of bone marrow origin as a novel approach for tolerance induction in transplantation.

Stem Cell Investig 2021 19;8. Epub 2021 Apr 19.

Department of Orthopaedics, University of Illinois at Chicago, Chicago, IL, USA.

Background: Cell therapies and chimerism-based strategies are currently the most successful approach for tolerance induction in transplantation. This study aimed to establish and characterize novel Donor Recipient Chimeric Ccell (DRCC) therapy of bone marrow (BM) origin presenting donor-recipient phenotype to support tolerance induction.

Methods: fusions of fully MHC-mismatched BM cells from ACI (RT1) and Lewis (RT1) rats were performed using polyethylene-glycol (PEG). Read More

View Article and Full-Text PDF

Establishing a Reference Dose-Response Calibration Curve for Dicentric Chromosome Aberrations to Assess Accidental Radiation Exposure in Saudi Arabia.

Front Public Health 2020 15;8:599194. Epub 2020 Dec 15.

Radiation Biology Section, Biomedical Physics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

In cases of nuclear and radiological accidents, public health and emergency response need to assess the magnitude of radiation exposure regardless of whether they arise from disaster, negligence, or deliberate act. Here we report the establishment of a national reference dose-response calibration curve (DRCC) for dicentric chromosome (DC), prerequisite to assess radiation doses received in accidental exposures. Peripheral blood samples were collected from 10 volunteers (aged 20-40 years, median = 29 years) of both sexes (three females and seven males). Read More

View Article and Full-Text PDF

Developmental Retrocerebellar Cysts: A New Classification for Neuroendoscopic Management and Systematic Review.

World Neurosurg 2019 Dec 20;132:e654-e664. Epub 2019 Aug 20.

Department of Neurosurgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Objective: Posterior fossa cystic malformations are diversely classified with considerable overlap without therapeutic relevance. These cysts posterior to the cerebellum, presenting in children younger than 5 years, are labeled developmental retrocerebellar cysts (DRCCs) under a new classification in relation to neuroendoscopy.

Methods: DRCC was categorized as type 0 for asymptomatic enlarged cistern magna and was not treated. Read More

View Article and Full-Text PDF
December 2019

Relationship between health care insurance status, social determinants and prevalence of diabetes-related microvascular complications in patients with type 1 diabetes: a nationwide survey in Brazil.

Acta Diabetol 2019 Jun 13;56(6):697-705. Epub 2019 Mar 13.

Bauru's Diabetics Association, Rua Saint Martin 27-07, Bauru, São Paulo, CEP 17012-433, Brazil.

Aims: To evaluate the relationship between social determinants, health care insurance status and occurrence of diabetes-related chronic complications (DRCC) in Brazilian patients with type 1 diabetes.

Methods: A multicenter cross-sectional study conducted between August 2011 and August 2014 in 14 public clinics in 10 Brazilian cities. Data were obtained from 1760 patients, aged 29. Read More

View Article and Full-Text PDF

An Intimate Role for Adult Dorsal Root Ganglia Resident Cycling Cells in the Generation of Local Macrophages and Satellite Glial Cells.

J Neuropathol Exp Neurol 2018 10;77(10):929-941

Neuroscience and Mental Health Institute.

The intricate interactions between neurons, glial, and inflammatory cells within peripheral ganglia are physiologically important, but not well explored. Here, we show that adult dorsal root ganglia (DRG) contain populations of self-renewing cells, collectively referred as DRG resident cycling cells (DRCCs), that are active not only in "quiescent" ganglia but also accelerate their turnover in response to distal axotomy. An unexpected proportion of DRCCs were resident macrophages. Read More

View Article and Full-Text PDF
October 2018

Jansen-MIDAS: A multi-level photomicrograph segmentation software based on isotropic undecimated wavelets.

Microsc Res Tech 2018 Jan 20;81(1):22-32. Epub 2017 Oct 20.

DFQB - Departamento de Física, Química e Biologia, FCT - Faculdade de Ciências e Tecnologia, UNESP - Univ Estadual Paulista, Presidente Prudente, São Paulo, 19060-900, Brazil.

Image segmentation, the process of separating the elements within a picture, is frequently used for obtaining information from photomicrographs. Segmentation methods should be used with reservations, since incorrect results can mislead when interpreting regions of interest (ROI). This decreases the success rate of extra procedures. Read More

View Article and Full-Text PDF
January 2018

The gold nun: a case of a gold ligature from the 15 century and the origins of restorative dentistry in Europe.

Anthropol Anz 2017 Dec 17;74(4):347-353. Epub 2017 Aug 17.

DMD, PhDs, Department of Dentistry, Faculty of Medicine, University of Coimbra, Portugal

Abstract: We here report the discovery of a gold dental ligature from the late 15 century, at the Convent of Santa Clara-a-Velha, in the city of Coimbra, Portugal. A medieval Clare's nun presented the left upper lateral incisor splinted to the canine, since the others three incisors were lost, most probably due to an aggressive periodontal disease. The convent is associated with the medieval upper class, which was well known for its consumption of high levels of sugar. Read More

View Article and Full-Text PDF
December 2017

Executive function after severe childhood traumatic brain injury - Age-at-injury vulnerability periods: The TGE prospective longitudinal study.

Ann Phys Rehabil Med 2017 Apr 25;60(2):74-82. Epub 2016 Aug 25.

Université Descartes Paris5, Hôpital Universitaire Necker, Anesthesiology Department, Pediatric Neuro Critical Care Unit, 75015 Paris, France.

Background: Executive function (EF) impairment is a major predictor of overall outcome after traumatic brain injury (TBI). TBI severity is a factor of poor outcome, but most studies include a majority of children with mild and moderate TBI. The aims of this study were to estimate EF impairment after severe childhood TBI and to explore factors predicting EF outcome. Read More

View Article and Full-Text PDF

Prolonged isolated red blood cell transfusion requirement after allogeneic blood stem cell transplantation: identification of patients at risk.

Transfusion 2010 Mar 19;50(3):649-55. Epub 2009 Nov 19.

Departments of Pediatric Hematology/Oncology, Medizinische Hochschule Hannover, Hannover, Germany.

Background: Delayed donor red blood cell chimerism (DRCC), pure red blood cell aplasia (PRCA), and autoimmune hemolytic anemia (AIHA) are poorly documented complications after hematopoietic cell transplantation (HCT). The clinical variable "prolonged isolated red blood cell transfusion requirement" (PRTR) was evaluated as a trigger for an extended diagnostic workup.

Study Design And Methods: PRTR was defined as the need for red blood cell (RBC) transfusions beyond Day 60 after HCT. Read More

View Article and Full-Text PDF

Butyrolactones from Aspergillus terreus.

Chem Pharm Bull (Tokyo) 2000 Apr;48(4):559-62

Dr Reddy's Research Foundation, Miyapur, Hyderabad, India.

In the process development of lovastatin using Aspergillus terreus DRCC 152 in solid state fermentation, we have isolated a new butyrolactone-IV (3) along with the previously reported butyrolactone-I (1) and butyrolactone-II (2) produced under submerged conditions. The structure of compound 3 has been characterized as 3-hydroxy-5-[2-(1-hydroxy-1-methylethyl)-2(R)-2,3-dihydro-benzo[b]furan- 5 ylmethyl]-4-(4-hydroxyphenyl)-5-methoxycarbonyl-(5R)-2,5-dihydro-2 -furanone on the basis of spectroscopic studies. The absolute stereochemistry has been determined by single crystal X-ray diffraction studies. Read More

View Article and Full-Text PDF

[70 years of educational, research and therapeutic-preventive activity at the Psychiatric Clinic of Brno University].

Authors:
J Svestka M Bouchal

Cesk Psychiatr 1990 Dec;86(6):399-403

Psychiatrická klinika LF MU, Brno.

The Medical Faculty of the Masaryk University in Brno and thus also the psychiatric department was established by act no. 50 of January 28, 1919 in the newly founded Czechoslovak Republic. Records on care of the mentally sick in municipal hospitals, later in the hospital of the brethren of mercy and finally in the municipal hospital in Pekarská street date to the 16th century. Read More

View Article and Full-Text PDF
December 1990
  • Page 1 of 1