11,973 results match your criteria dpph radical


The evaluation of phenolic content, in vitro antioxidant and antibacterial activity of Mentha piperita extracts obtained by natural deep eutectic solvents.

Food Chem 2021 Jun 2;362:130226. Epub 2021 Jun 2.

Chemistry&Biochemistry Laboratory, Department of Field and Vegetable Crops, Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, 21000 Novi Sad, Serbia.

The focus of this study was to evaluate whether six choline chloride-based natural deep eutectic solvents (NADES) could serve as solvents for the extraction of bioactives from the leaves of Mentha piperita. NADES extracted significantly higher amounts of phenols from peppermint than 70% ethanol and may be useful in the extraction of targeted major compounds from peppermint, like rosmarinic acid, at a similar level as 70% ethanol. The microdilution method for in vitro antibacterial activity showed that all NADES exhibit bacterial growth inhibition at a lower concentration than 70% ethanol, especially NADESs containing organic acids. Read More

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Comprehensive evaluation of two Astragalus species (A. campylosema and A. hirsutus) based on biological, toxicological properties and chemical profiling.

Food Chem Toxicol 2021 Jun 8:112330. Epub 2021 Jun 8.

Department of Health Sciences, Faculty of Medicine and Health Sciences, University of Mauritius, Réduit, Mauritius.

Astragalus L. (Fabaceae) is an important genus with numerous species having various traditional medicinal uses making them of interest for scientific investigations to ascertain their therapeutic benefits. In the present study, the quantitative polyphenolic profiles of methanolic extracts from different parts (leaves, flowers, and roots) of two endemic Astragalus species growing in Turkey, i. Read More

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New insight into antimicrobial activities of Linaria ventricosa essential oil and its synergetic effect with conventional antibiotics.

Arch Microbiol 2021 Jun 11. Epub 2021 Jun 11.

Laboratory of Microbial Biotechnologies, Agrosciences and Environment, Faculty of Science, Semlalia University Cadi Ayyad, Marrakech, Morocco.

The purpose of the present study was to determine for the first time the volatile constituents, the antioxidant and antimicrobial activities of the essential oil (EO) of the endemic Moroccan Linaria ventricosa, alone or in combination with four known antibiotics. The major constituents were 2-methoxy-4-vinylphenol (17.4%), α-terpinene (13. Read More

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One-step self-assembly of curcumin-loaded zein/sophorolipid nanoparticles: physicochemical stability, redispersibility, solubility and bioaccessibility.

Food Funct 2021 Jun 11. Epub 2021 Jun 11.

College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong Province 266003, People's Republic of China.

Curcumin, a polyphenolic compound isolated from turmeric, exhibits various biological activities. The application of this nutraceutical in foods, however, is limited due to its extreme hydrophobicity, inferior stability, and poor bioaccessibility. The purpose of this paper is to prepare alcohol-free curcumin-loaded zein/sophorolipid nanoparticles (Cur-Z/SNPs) by one-step self-assembly to overcome the abovementioned challenges of curcumin. Read More

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Preparation of acylated blueberry anthocyanins through an enzymatic method in an aqueous/organic phase: effects on their colour stability and pH-response characteristics.

Food Funct 2021 Jun 11. Epub 2021 Jun 11.

School of Biological Science and Biotechnology, Fujian University Key Laboratory of Characteristics Garden Plants Resource in Fujian and Taiwan, Minnan Normal University, Zhangzhou, 363000, P.R. China.

To explore the potential of anthocyanins in pH-colour responsive intelligent packaging and improve the stability of the pigments, 3,4,5-trimethoxybenzoic acid and gallic acid were grafted onto blueberry anthocyanins via enzyme-catalysed grafting. The structural analysis based on UV-vis and IR spectroscopy showed that the two acids were successfully grafted onto the blueberry anthocyanins. The acylation degrees of the 3,4,5-trimethoxybenzoic acid-acylated anthocyanin (Tr-An) and gallic acid-acylated anthocyanin (Ga-An) were 6. Read More

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Effect of the main constituents of Pistacia lentiscus leaves against the DPPH radical and xanthine oxidase: experimental and theoretical study.

J Biomol Struct Dyn 2021 Jun 11:1-15. Epub 2021 Jun 11.

Laboratoire des Matériaux Polymères Multiphasiques, LMPMP, Université Ferhat ABBAS Sétif-1, Sétif, Algeria.

The aim of this work is to study the content of phenolic compounds in leaves and their antioxidant effect. After extracting the phenolic compounds, fractionation by liquid/liquid partition with increasing polarity gives five extracts. Three of them (ButF, AqF and ButA) were found to have good antioxidant activity. Read More

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Nutritional composition and proteomic analysis of soft-shelled turtle (Pelodiscus sinensis) egg and identification of oligopeptides with alpha-glucosidase inhibitory activity.

Food Res Int 2021 Jul 13;145:110414. Epub 2021 May 13.

State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, Jiangxi, PR China. Electronic address:

This study aimed to explore nutritional compositions and proteomics of soft-shelled turtle (SST) egg, as well as identify potential antidiabetic oligopeptides with α-glucosidase inhibitory property. Results revealed that SST egg is a promising source of highly nutritious proteins and minerals (54.64% and 5. Read More

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Bioavailability and radical scavenging power of phenolic compounds of cocoa and coffee mixtures.

Food Sci Technol Int 2021 Jun 10:10820132211023258. Epub 2021 Jun 10.

Laboratorio de Fitoquímica y Alimentos Saludables, Departamento de Ciencia y Tecnología de Alimentos, CEBAS-CSIC, Campus Universitario de Espinardo, Murcia, Spain.

Cocoa and coffee are natural sources of phenolic compounds, which are degraded during beans processing of both. For this reason, there is an interest in obtaining extracts of these bio compounds. The aim of this study was uncovering the radical scavenging activity (AC) of mixtures of cocoa and coffee extracts, and the bioavailability of their phenolic compounds, resorting to in vitro models: DPPH and ORAC antioxidant methods, and the characterization of the trans-epithelial transport of cocoa and coffee phenolics through Caco-2 cells monolayer model of the intestinal barrier. Read More

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Biodegradable Polymers and Gold Nanoparticle-Decorated Skin Substitutes: Synthesis, Characterization, and In Vitro Biological Activities.

Appl Biochem Biotechnol 2021 Jun 10. Epub 2021 Jun 10.

Department of Chemistry, Avinashilingam Institute for Home Science and Higher Education for Women, 641043, Coimbatore, India.

Skin substitutes are a restorative material used to treat many skin injuries by replacing or masking the wound. It is also capable of producing an original skin type. In this study, gold nanoparticle-aided skin substitutes were prepared using biodegradable materials (chitosan, sodium alginate, and gelatin) under the magnetic stirring method. Read More

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Experimental and Computational Evaluation of Extraction Procedure and Scavenging Capacity of Sweet Basil Extracts (Ocimum basilicum L.).

Plant Foods Hum Nutr 2021 Jun 9. Epub 2021 Jun 9.

Faculty of Science, University of Novi Sad, Trg Dositeja Obradovića 3, Novi Sad, Serbia.

The possibility to prevent nutrition-related diseases that include scavenge of free radicals and to block chain reactions is very important and significant for human well-being. The aim of this study was to analyse different basil extracts, determine the relationship between total phenolic/flavonoid content and antioxidant activity in order to optimize its application in industry. The extraction involved different solvents (ethanol, methanol and water), extraction time (10 and 30 min and 24, 48 and 72 h), plant fragmentation level (0. Read More

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Formation and characterization of mechanochemically generated free lignin radicals from olive seeds.

Authors:
Fatma Demir

Turk J Chem 2021 28;45(2):282-294. Epub 2021 Apr 28.

Department of Chemistry, Faculty of Science, Bilkent University, Ankara Turkey.

In this study, formation and quantification of mechanochemically generated free radicals of lignin were evaluated after the extraction of lignin from olive seeds and detailed lignin characterization was performed. Lignin was extracted from crushed olive seeds as an insoluble solid using Klason method. Isolated lignin was mechanochemically grinded under cryo conditions using Cryomill and particlesizes were determined by using Zeta Sizer, structural changes were followed by XRD and FTIR-ATR; thermal stabilities were tracked by TGA and DSC. Read More

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Utilization of Maillard reaction in moist-dry-heating system to enhance physicochemical and antioxidative properties of dried whole longan fruit.

Heliyon 2021 May 22;7(5):e07094. Epub 2021 May 22.

Division of Product Development Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.

This research aimed to enhance the physicochemical and antioxidant properties of dried whole longan fruit using Maillard reaction or non-enzymatic glycosylation (glycation) in a moist-dry-heating system at 60 °C with approximately 75% relative humidity for 5-50 days. During Maillard reaction, the browning index (BI) of the fruits increased significantly while lightless, redness and yellowness decreased. Interestingly, the rare sugars especially D-psicose and D-allose gradually increased by 2-3 folds when compared to the initial Maillard reaction. Read More

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High or low temperature extraction, which is more conducive to Triphala against chronic pharyngitis?

Biomed Pharmacother 2021 Jun 4;140:111787. Epub 2021 Jun 4.

State Key Laboratory of Southwest Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address:

Objective: Explore the effects of high-temperature reflux extraction and low-temperature decompressing inner ebullition on Triphala's chemical composition and anti-chronic pharyngitis activity.

Methods: The network pharmacology was used to analyze the material basis, targets and pathways of Triphala for chronic pharyngitis. HPLC were used to compare the fingerprint profile and content of components between the two extracts. Read More

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Fatty acid composition, enzyme inhibitory effect, antioxidant and anticancer activity of extract from Saponaria prostrata WILLD. subsp. anatolica HEDGE.

Bioorg Chem 2021 May 27;113:105032. Epub 2021 May 27.

Department of Biotechnology, Faculty of Science, Bartin University, 74100 Bartin, Turkey; Department of Chemistry, Faculty of Science, Istinye University, Istanbul, Turkey. Electronic address:

This study attempts to evaluate the antioxidant, enzyme inhibitory, and anticancer properties as well as fatty acid compositions of endemic Saponaria prostrata WILLD. subsp. anatolica HEDGE. Read More

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Assessment of total (anti)oxidant status in goat kids.

Arch Anim Breed 2021 26;64(1):139-146. Epub 2021 Apr 26.

Department of Veterinary Sciences, Polo Universitario Annunziata, University of Messina, 98168 Messina, Italy.

The redox potential of goat serum was assessed by different spectrophotometric assays. Among them, three methods are commonly applied for the evaluation of the oxidative (reactive oxygen metabolites, ROMs, and total oxidant status, TOS) and nitrosative (NO metabolites, ) stress, and four methods for the evaluation of the antioxidant status: the total antioxidant capacity (TAC) based on the ferric reducing ability of plasma (FRAP), the total antioxidant activity (TAA) based on the reduction of the coloured ABTS radical cation, the free radical scavenging activity (FRSA) based on the reduction of the purple DPPH , and the total thiol levels (TTLs) based on their interaction with DTNB to form a highly coloured anion. Besides, myeloperoxidase (MPO) and ceruloplasmin oxidase (CP) activities were also assessed. Read More

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Solvent Dependency of Sorghum Bran Phytochemicals Acting as Potential Antioxidants and Antibacterial Agents.

Food Technol Biotechnol 2021 Mar;59(1):31-43

Department of Basic and Applies Sciences, National Institute of Food Technology Entrepreneurship and Management, Sector - 56, HSIIDC Industrial Estate, Kundli, Sonipat, 131028 Haryana, India.

Research Background: Sorghum bran, although considered as an agricultural waste, is an abundant source of various bioactive compounds. These bioactive compounds require specific extraction with particular solvents and therefore ionic liquid and three different conventional solvents, anhydrous methanol, acidified methanol and water were used in this work.

Experimental Approach: To evaluate the phytochemicals in the different sorghum bran extracts, total phenol content, flavonoids, condensed tannins and anthocyanins were determined as per standard protocols. Read More

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Synthesis of 4,4'-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) and evaluation of their antioxidant and anticancer activities.

BMC Chem 2021 Jun 3;15(1):38. Epub 2021 Jun 3.

Centro de Investigación Biomédica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, 170527, Quito, Ecuador.

Background: Pyrazoles have attracted particular attention due to the diverse biological activities associated with this heterocyclic system, and some have been shown to be cytotoxic to several human cell lines. Several drugs currently on the market have this heterocycle as the key structural motif, and some have been approved for the treatment of different types of cancer.

Results: 4,4'-(Arylmethylene)bis(1H-pyrazol-5-ols) derivatives 3a-q were synthetized by a three components reaction of 3-methyl-1-phenyl-5-pyrazolone (1) with various benzaldehydes 2 catalyzed by sodium acetate at room temperature. Read More

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Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors.

Comb Chem High Throughput Screen 2021 Jun 3. Epub 2021 Jun 3.

Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Amrita Health Science Campus, Kochi-682 041, India.

Background: Chalcones with methoxy substituents are considered as a promising framework for the inhibition of monoamine oxidase (MAO) enzymes.

Methods: A series of nine trimethoxy substituted chalcones (TMa-TMi) was synthesized and evaluated as a multifunctional class of MAO inhibitors. All the synthesized compounds were investigated for their in vitro MAO inhibition, kinetics, reversibility, blood-brain barrier (BBB) permeation, and cytotoxicity and antioxidant potentials. Read More

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Evaluation of Microwave-Assisted Extraction Method for Preparation and Assessment of Thai Herbal Medicine Oral Tablets With Enriched Phytochemical Compounds.

AAPS PharmSciTech 2021 Jun 2;22(5):167. Epub 2021 Jun 2.

School of Health Science, Mae Fah Luang University, Muang, Chiang Rai, 57100, Thailand.

In developing countries, populations have employed herbal medicines for primary health care because they are believed to be more appropriate to the human body and have less side effects than chemically synthesized drugs. The present study aimed to develop and evaluate herbal tablets incorporated with a Thai traditional medicinal extract, U-pa-ri-waat (URW), using microwave-assisted extraction (MAE). The extraction efficiency for URW using MAE and traditional solvent extraction was compared based on the percent yield after spray drying. Read More

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Enhancing the Radical Scavenging Activity and UV Resistance of Lignin Nanoparticles via Surface Mannich Amination toward a Biobased Antioxidant.

Biomacromolecules 2021 Jun 2. Epub 2021 Jun 2.

The Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, Jiangnan University, Wuxi 214122, China.

In recent years, lignin specific activities, such as antioxidation and antibacterial and anti-ultraviolet performance, have drawn more and more attention. Nevertheless, the insufficient radical scavenging (antioxidation) activity has become one of the main drawbacks that limits its high-value application. In this study, lignin nanoparticles (LNPs) were prepared via a facile acid treatment strategy. Read More

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Comparative Analysis of Metabolite Profiling of Leaf and the Anti-Obesity Effect through Regulating Lipid Metabolism.

Int J Environ Res Public Health 2021 May 24;18(11). Epub 2021 May 24.

Department of Food Science and Nutrition, College of Health Science, Dong-A University, Busan 49315, Korea.

This study investigated the effects of () extract in obesity and abnormal lipid metabolism in mice fed high fat diet (HFD). Fruit, root, stem, and leaf extracts of were obtained using distilled water, 70% ethanol and 95% hexane. leaf distilled water extract (MCLW) showed the highest antioxidant activity in both 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity tests and reducing power. Read More

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UHPLC-ESI-QTOF-MS/MS Metabolite Profiling of the Antioxidant and Antidiabetic Activities of Red Cabbage and Broccoli Seeds and Sprouts.

Antioxidants (Basel) 2021 May 26;10(6). Epub 2021 May 26.

Department of Food Science and Biotechnology, College of Agriculture and Life Sciences, Kangwon National University, Chuncheon 24341, Gangwon-do, Korea.

The antioxidant and antidiabetic properties and metabolite profiling of ethanol extracts of red cabbage (RC) and broccoli (BR) seeds and sprouts were investigated in this study. The total phenolic, flavonoid, and saponin contents were in the ranges of 385.4-480. Read More

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Spent Grain from Malt Whisky: Assessment of the Phenolic Compounds.

Molecules 2021 May 27;26(11). Epub 2021 May 27.

Faculty of Food Engineering, Stefan cel Mare University of Suceava, 720229 Suceava, Romania.

In order to extract antioxidant phenolic compounds from spent grain (SG) two extraction methods were studied: the ultrasound-assisted method (US) and the Ultra-Turrax method (high stirring rate) (UT). Liquid to solid ratios, solvent concentration, time, and temperature/stirring rate were optimized. Spent grain extracts were analyzed for their total phenol content (TPC) (0. Read More

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The Anti-Oxidative and Anti-Neuroinflammatory Effects of by Heme Oxygenase-1 Induction in BV2 and HT22 Cells.

Antioxidants (Basel) 2021 May 27;10(6). Epub 2021 May 27.

College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Korea.

is used as a traditional medicinal agent and exhibits various pharmacological effects. In this study, we found that the 70% EtOH extract contained 34.37 ± 0. Read More

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Myeloperoxidase Inhibitory and Antioxidant Activities of ()-2-Hydroxy-α-aminocinnamic Acids Obtained through Microwave-Assisted Synthesis.

Pharmaceuticals (Basel) 2021 May 27;14(6). Epub 2021 May 27.

Laboratorio de Química Supramolecular y Nanociencias, Unidad Profesional Interdisciplinaria de Biotecnología, Instituto Politécnico Nacional, Avenida Acueducto s/n, Barrio la Laguna Ticomán, Ciudad de México 07340, Mexico.

Myeloperoxidase (MPO) is an enzyme present in human neutrophils, whose main role is to provide defenses against invading pathogens. However, highly reactive oxygen species (ROS), such as HOCl, are generated from MPO activity, leading to chronic diseases. Herein, we report the microwave-assisted synthesis of a new series of stable ()-(2-hydroxy)-α-aminocinnamic acids, in good yields, which are structurally analogous to the natural products ()-2-hydroxycinnamic acids. Read More

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Production and Characterization of Sumac PlantCrystals: Influence of High-Pressure Homogenization on Antioxidant Activity of Sumac ( L.).

Plants (Basel) 2021 May 23;10(6). Epub 2021 May 23.

Department of Pharmaceutics and Biopharmaceutics, Philipps-Universität Marburg, Robert-Koch-Str. 4, 35037 Marburg, Germany.

Oxidative stress diseases are usually treated or prevented by using antioxidants from natural or artificial sources. However, as a sustainable source of phytochemicals, plants got a renewed interest in obtaining their active agents using green extraction technologies, i.e. Read More

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Antioxidant and Anticholinesterase Activities of Extracts and Phytochemicals of Leaves.

Molecules 2021 May 30;26(11). Epub 2021 May 30.

Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand.

Bioassay-guided separation of young leaves extracts of (Blume) Merr. & L.M. Read More

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Native Chilean Berries Preservation and In Vitro Studies of a Polyphenol Highly Antioxidant Extract from Maqui as a Potential Agent against Inflammatory Diseases.

Antioxidants (Basel) 2021 May 25;10(6). Epub 2021 May 25.

Departamento de Química Orgánica y Farmacéutica, Universidad de Sevilla, c/Prof García González nº 2, 41012 Sevilla, Spain.

The best conservation method for native Chilean berries has been investigated in combination with an implemented large-scale extract of maqui berry, rich in total polyphenols and anthocyanin to be tested in intestinal epithelial and immune cells. The methanolic extract was obtained from lyophilized and analyzed maqui berries using Folin-Ciocalteu to quantify the total polyphenol content, as well as 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), and oxygen radical absorbance capacity (ORAC) to measure the antioxidant capacity. Determination of maqui's anthocyanins profile was performed by ultra-high-performance liquid chromatography (UHPLC-MS/MS). Read More

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Bioactive Phenolic Metabolites from Adriatic Brown Algae and (Dictyotaceae).

Foods 2021 May 25;10(6). Epub 2021 May 25.

Department of Food Technology and Biotechnology, Faculty of Chemistry and Technology, University of Split, R. Boškovića 35, HR-21000 Split, Croatia.

In this study, the influences of temperature (20, 40 and 60 °C) and extraction solvents (water, ethanol) on the ultrasound-assisted extraction of phenolics from the Adriatic macroalgae and were studied. The extracts were analysed for major phenolic sub-groups (total phenolics, flavonoids and tannins) using spectrometric methods, while the individual phenolics were detected by HPLC. The antioxidant activities were evaluated using three methods: Ferric Reducing/Antioxidant Power (FRAP), scavenging of the stabile 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and Oxygen Radical Antioxidant Capacity (ORAC). Read More

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Exogenous Application of Zinc to Mitigate the Salt Stress in (L.) Wilczek-Evaluation of Physiological and Biochemical Processes.

Plants (Basel) 2021 May 18;10(5). Epub 2021 May 18.

Department of Bioresources, University of Kashmir, Hazratbal, Srinagar 190006, India.

Salt stress adversely affects the growth and productivity of crops. However, reports suggest that the application of various micronutrients could help the plant to cope with this stress. Hence, the objective of the study was to examine the effect of exogenous application of Zinc (Zn) on salt tolerance in (L. Read More

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