Chem Asian J 2021 Sep 22. Epub 2021 Sep 22.
Indian Institute of Science Education and Research Kolkata, Department of Chemical Sciences, BCKV campus, 741252, Mohanpur, INDIA.
Half-sandwich Ru II complexes, [(YZ)Ru II (η 6 -arene)(X)]+, (YZ= chelating bidentate ligand, X = halide), with N , N and N , O coordination ( 1-9 ) show significant antiproliferative activity against the metastatic triple negative breast carcinoma (MDA-MB-231). 3-aminobenzoic acid or its methyl ester is used in all the ligands while varying the aldehyde for N , N and N , O coordination. In the N,N coordinated complex the coordinated halide(X) is varied for enhancing stability in solution (X = Cl, I). Read More