8,378 results match your criteria distinct morphologically

Heterocapsa busanensis sp. nov. (Peridiniales, Dinophyceae): A new marine thecate dinoflagellate from Korean coastal waters.

Eur J Protistol 2021 Apr 23;79:125797. Epub 2021 Apr 23.

Division of Earth Environmental System Science, Pukyong National University, Busan 48513, Republic of Korea; Department of Oceanography, Pukyong National University, Busan 48513, Republic of Korea. Electronic address:

During daily monitoring in Yongho Bay off Busan, Korea in 2019, an isolate of the dinoflagellate genus Heterocapsa was established in clonal culture. Light and electron microscopic examination revealed that the isolate was ellipsoid in shape, exhibiting a thecal plate arrangement (Po, cp, X, 5', 3a, 7″, 6c, 5s, 5‴, 2'''') consistent with most other Heterocapsa species. A large, elongated nucleus was positioned on the left side of the cell, a single reticulate chloroplast was located peripherally, and a single, starch-sheathed, spherical pyrenoid was present in the episome or near the cingulum. Read More

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Leep1 interacts with PIP3 and the Scar/WAVE complex to regulate cell migration and macropinocytosis.

J Cell Biol 2021 Jul 12;220(7). Epub 2021 May 12.

National Laboratory of Biomacromolecules, Chinese Academy of Sciences Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

Polarity is essential for diverse functions in many cell types. Establishing polarity requires targeting a network of specific signaling and cytoskeleton molecules to different subregions of the cell, yet the full complement of polarity regulators and how their activities are integrated over space and time to form morphologically and functionally distinct domains remain to be uncovered. Here, by using the model system Dictyostelium and exploiting the characteristic chemoattractant-stimulated translocation of polarly distributed molecules, we developed a proteomic screening approach, through which we identified a leucine-rich repeat domain-containing protein we named Leep1 as a novel polarity regulator. Read More

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Copro-PCR in the detection and confirmation of Toxoplasma gondii oocysts in feces of stray and domiciled cats.

Rev Bras Parasitol Vet 2021 10;30(2):e000621. Epub 2021 May 10.

Laboratório de Estudos da Relação Parasito-Hospedeiro, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás - UFG, Goiânia, GO, Brasil.

Molecular methods such as Copro-PCR stand out in the diagnosis of T. gondii, because they are highly sensitive and specific, and can distinguish T. gondii from other morphologically similar coccids. Read More

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Generative adversarial network for glioblastoma ensures morphologic variations and improves diagnostic model for isocitrate dehydrogenase mutant type.

Sci Rep 2021 May 10;11(1):9912. Epub 2021 May 10.

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul, 05505, Korea.

Generative adversarial network (GAN) creates synthetic images to increase data quantity, but whether GAN ensures meaningful morphologic variations is still unknown. We investigated whether GAN-based synthetic images provide sufficient morphologic variations to improve molecular-based prediction, as a rare disease of isocitrate dehydrogenase (IDH)-mutant glioblastomas. GAN was initially trained on 500 normal brains and 110 IDH-mutant high-grade astocytomas, and paired contrast-enhanced T1-weighted and FLAIR MRI data were generated. Read More

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Distinct Brain-derived TDP-43 Strains from FTLD-TDP Subtypes Induce Diverse Morphological TDP-43 Aggregates and Spreading Patterns in vitro and in vivo.

Neuropathol Appl Neurobiol 2021 May 10. Epub 2021 May 10.

Center for Neurodegenerative Disease Research (CNDR), Institute on Aging, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

Aim: The heterogeneity in the distribution and morphological features of TAR DNA-binding protein-43 (TDP-43) pathology in the brains of frontotemporal lobar degeneration (FTLD-TDP) patients and their different clinical manifestations suggest that distinct pathological TDP-43 strains could play a role in this heterogeneity between different FTLD-TDP subtypes (A-E). Our aim was to evaluate the existence of distinct TDP-43 strains in the brains of different FTLD-TDP subtypes and characterize their specific seeding properties in vitro and in vivo.

Methods And Results: We used an inducible stable cell line expressing a mutant cytoplasmic TDP-43 (iGFP-NLSm) to evaluate the seeding properties of distinct pathological TDP-43 strains. Read More

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Recent achievements and doors opened for coccidian parasite research and development through transcriptomics of enteric sexual stages.

Mol Biochem Parasitol 2021 May 4;243:111373. Epub 2021 May 4.

School of Life Sciences, University of Technology Sydney, Ultimo, NSW 2007, Australia; Research School of Biology, Australian National University, Canberra, ACT 0200, Australia. Electronic address:

The Coccidia is the largest group of parasites within the Apicomplexa, a phylum of unicellular, obligate parasites characterized by the possession of an apical complex of organelles and structures in the asexual stages of their life cycles, as well as by a sexual reproductive phase that occurs enterically in host animals. Coccidian sexual reproduction involves morphologically distinct microgametes and macrogametes that combine to form a diploid zygote and, ultimately, following meiosis and mitosis, haploid, infectious sporozoites, inside sporocysts within an oocyst. Recent transcriptomic analyses have identified genes involved in coccidian sexual stage development and reproduction, including genes encoding for microgamete- and macrogamete-specific proteins with roles in gamete motility, fusion and fertilization, and in the formation of the resilient oocyst wall that allows coccidians to persist for long periods in the environment. Read More

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Low-Grade Oncocytic Tumor of Kidney (CK7-Positive, CD117-Negative): Incidence in a Single Institutional Experience with Clinicopathological and Molecular Characteristics.

Hum Pathol 2021 May 4. Epub 2021 May 4.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905. Electronic address:

Aims: Low-grade oncocytic tumor of the kidney (LOT) is characterized by cytoplasmic eosinophilia and a CK7-positive/CD117-negative immunophenotype. Morphologically, they exhibit overlapping features with oncocytoma and chromophobe renal cell carcinoma (chRCC). Our aim was to obtain long-term clinical follow-up data, clinicopathological and molecular characteristics, and incidence of LOT. Read More

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Verrucous Carcinoma of the Esophagus Is A Genetically Distinct Subtype of Esophageal Squamous Cell Carcinoma.

Histopathology 2021 May 7. Epub 2021 May 7.

Department of Pathology.

Aims: Esophageal verrucous carcinoma (VSCC) is a rare and morphologically distinct type of esophageal squamous cell carcinoma (SCC). Diagnosing VSCC on biopsy material is challenging given the lack of significant atypia and the presence of keratinizing epithelium and exophytic growth. The molecular pathogenesis of VSCC remains unclear. Read More

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Two new species of Hypostomus suckermouth armored catfishes (Teleostei: Loricariidae) from Central Brazil.

J Fish Biol 2021 May 6. Epub 2021 May 6.

Departamento de Zoologia, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, DF, Brazil.

We describe two new endemic Hypostomus species from central Brazil, which were previously identified as genetically distinct lineages in a recent genomic study that recommended their testing and potential description based on morphological data. A machine learning classification procedure (random forest) was used to investigate morphological variation and identify putatively diagnostic characters for these candidate species, and revealed that each is morphologically distinct. The new species Hypostomus cafuringa is characterized by small size, dark spots under a light background color, deeper caudal peduncle, and shorter first ray of the pectoral-fin and base of the dorsal-fin when compared to congeneric species from the region. Read More

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(Asteraceae), a new species from Humla, Nepal Himalayas.

PhytoKeys 2021 16;176:55-66. Epub 2021 Apr 16.

Central Department of Botany, Tribhuvan University, Kirtipur, Kathmandu, Nepal Tribhuvan University Kathmandu Nepal.

A new species S.K.Ghimire & H. Read More

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, a new and endangered species of Melastomataceae from China.

PhytoKeys 2021 16;176:33-42. Epub 2021 Apr 16.

College of Forestry and Landscape Architecture/Guangdong Key Laboratory for Innovative Development and Utilization of Forest Plant Germplasm, South China Agricultural University, Guangzhou 510642, Guangdong, China.

A new species of the genus , formerly considered monotypic, is here described as and illustrated based on molecular and morphological evidence. It is morphologically similar to in having a short stem, huge basal leaves, scorpioid cymes, and 5-merous flowers, but differs in having ribbed and pale yellow puberulent petioles, purple petals with a small white apical patch, connectives of longer stamens with a distinct dorsal short spur at their base, and wingless capsules. Due to the restricted distribution, small populations and horticultural potential of this new species, it should be categorized as an Endangered species (EN). Read More

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Morphological and genetic evidence supports the separation of two ants (Formicidae, Dolichoderinae) from the Atlantic Forest biome.

Zookeys 2021 22;1033:35-62. Epub 2021 Apr 22.

Facultad de Ciencias Básicas, Programa de Biología, Universidad del Magdalena, Carrera 32 # 22-08, Santa Marta, Magdalena, Colombia Universidad del Magdalena Santa Marta Colombia.

The taxonomic boundaries of many Neotropical ant species of the genus are still unclear. and are two morphologically similar taxa which occur sympatrically in the southern Atlantic Forest of Brazil. Some characters such as the scape length and head shape suggest that these taxa may be different species. Read More

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Immunohistochemical and Genetic Labeling of Hairy and Glabrous Skin Innervation.

Curr Protoc 2021 May;1(5):e121

Vollum Institute, Oregon Health & Science University, Portland, Oregon.

Cutaneous innervation is an essential component of the mammalian sensory nervous system. During development, genetically and morphologically diverse subtypes of sensory neurons use distinct molecular pathways to innervate end organs or form free nerve endings in glabrous and hairy skin. Peripheral neurons can be damaged by acute injury or degenerate due to chronic conditions including diabetes and chemotherapy, leading to peripheral neuropathy. Read More

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Tau immunotherapy is associated with glial responses in FTLD-tau.

Acta Neuropathol 2021 May 5. Epub 2021 May 5.

Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, 613A Stellar Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA.

Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are neuropathologic subtypes of frontotemporal lobar degeneration with tau inclusions (FTLD-tau), primary tauopathies in which intracellular tau aggregation contributes to neurodegeneration. Gosuranemab (BIIB092) is a humanized monoclonal antibody that binds to N-terminal tau. While Gosuranemab passive immunotherapy trials for PSP failed to demonstrate clinical benefit, Gosuranemab reduced N-terminal tau in the cerebrospinal fluid of transgenic mouse models and PSP patients. Read More

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Introducing a new pleosporalean family Sublophiostomataceae fam. nov. to accommodate Sublophiostoma gen. nov.

Sci Rep 2021 May 4;11(1):9496. Epub 2021 May 4.

Department of Entomology and Plant Pathology, Faculty of Agriculture, Chiang Mai University, Chiang Mai, 50200, Thailand.

Collections of microfungi on bamboo and grasses in Thailand revealed an interesting species morphologically resembling Lophiostoma, but which can be distinguished from the latter based on multi-locus phylogeny. In this paper, a new genus, Sublophiostoma is introduced to accommodate the taxon, S. thailandica sp. Read More

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Effect of sodium alginate molecular structure on electrospun membrane cell adhesion.

Mater Sci Eng C Mater Biol Appl 2021 May 26;124:112067. Epub 2021 Mar 26.

Department of Chemistry and Industrial Chemistry, University of Genoa, Via Dodecaneso 31, 16146 Genoa, Italy. Electronic address:

Alginate-based electrospun nanofibers prepared via electrospinning technique represent a class of materials with promising applications in the biomedical and pharmaceutical industries. However, to date, the effect of alginate molecular mass and block composition on the biological response of such systems remains to some extent unclear. As such, in the present work, three alginates (i. Read More

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A tale of two morphs: developmental patterns and mechanisms of seed coat differentiation in the dimorphic diaspore model Aethionema arabicum (Brassicaceae).

Plant J 2021 May 4. Epub 2021 May 4.

Department of Biological Sciences, Royal Holloway University of London, Egham, TW20 0EX, United Kingdom.

The developmental transition from a fertilised ovule to a dispersed diaspore (seed or fruit) involves complex differentiation processes of the ovule's integuments leading to the diversity in mature seed coat structures in angiosperms. In this study, comparative imaging and transcriptome analysis were combined to investigate the morph-specific developmental differences during outer seed coat differentiation and mucilage production in Aethionema arabicum, the Brassicaceae model for diaspore dimorphism. One of the intriguing adaptations of this species is the production and dispersal of morphologically distinct, mucilaginous and non-mucilaginous diaspores from the same plant (dimorphism). Read More

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Matrix adhesion and remodeling diversifies modes of cancer invasion across spatial scales.

J Theor Biol 2021 Apr 29:110733. Epub 2021 Apr 29.

Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, 560012 India. Electronic address:

The metastasis of malignant epithelial tumors begins with the egress of transformed cells from the confines of their basement membrane (BM) to their surrounding collagen-rich stroma. Invasion can be morphologically diverse: when breast cancer cells are separately cultured within BM-like matrix, collagen I (Coll I), or a combination of both, they exhibit collective-, dispersed mesenchymal-, and a mixed collective-dispersed (multimodal)- invasion, respectively. In this paper, we asked how distinct these invasive modes are with respect to the cellular and microenvironmental cues that drive them. Read More

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On the diversity and clinical importance of Acanthamoeba spp. from Group 1.

Daniele Corsaro

Parasitol Res 2021 Apr 30. Epub 2021 Apr 30.

CHLAREAS, 12, rue du Maconnais, F-54500, Vandoeuvre-lès-Nancy, France.

Group 1 acanthamoebae are morphologically and phylogenetically distinct from all other Acanthamoeba species. They include five species, each labelled by its genotype: A. astronyxis (T7), A. Read More

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Landscape resistance constrains hybridization across contact zones in a reproductively and morphologically polymorphic salamander.

Sci Rep 2021 Apr 29;11(1):9259. Epub 2021 Apr 29.

CIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos da Universidade do Porto, Instituto de Ciências Agrárias de Vairão. R. Padre Armando Quintas, 4485-661, Vairão, Portugal.

Explicitly accounting for phenotypic differentiation together with environmental heterogeneity is crucial to understand the evolutionary dynamics in hybrid zones. Species showing intra-specific variation in phenotypic traits that meet across environmentally heterogeneous regions constitute excellent natural settings to study the role of phenotypic differentiation and environmental factors in shaping the spatial extent and patterns of admixture in hybrid zones. We studied three environmentally distinct contact zones where morphologically and reproductively divergent subspecies of Salamandra salamandra co-occur: the pueriparous S. Read More

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Whole-exome Sequencing of Epstein-Barr Virus-associated Pulmonary Carcinoma With Low Lymphocytic Infiltration Shows Molecular Features Similar to Those of Classic Pulmonary Lymphoepithelioma-like Carcinoma: Evidence to Support Grouping Together as One Disease Entity.

Am J Surg Pathol 2021 Apr 29. Epub 2021 Apr 29.

Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital School of Medicine Institute of Biomedical Informatics Department of Biotechnology and Laboratory Science in Medicine Institute of Clinical Medicine, National Yang Ming Chiao Tung University Department of Pathology, Taipei Hospital, Ministry of Health and Welfare, Taipei, Taiwan.

Pulmonary lymphoepithelioma-like carcinoma (LELC) is a distinct type of Epstein-Barr virus (EBV)-associated non-small cell carcinoma characterized by a syncytial growth pattern with heavy lymphocytic infiltration. We recently identified a group of non-small cell carcinomas, which are also associated with EBV but lack significant lymphocytic infiltration. These EBV-associated pulmonary carcinomas with low lymphocytic infiltration morphologically resemble nonkeratinizing squamous cell carcinoma, but their patient characteristics are more similar to those of LELC, including female sex and nonsmoking status. Read More

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Strengthening Structures in the Petiole-Lamina Junction of Peltate Leaves.

Biomimetics (Basel) 2021 Apr 2;6(2). Epub 2021 Apr 2.

Department of Biology, Faculty of Science, Institute of Botany, Technische Universität Dresden, 01062 Dresden, Germany.

Peltate- or umbrella- shaped leaves are characterised by a petiole more or less centrally attached to the lamina on the abaxial side. The transition from the petiole to lamina in peltate leaves resembles a significant and abrupt geometrical change from a beam to a plate in a very compact shape. Since these leaves have not been subject of many studies, the distribution of that specific leaf morphology in the plant kingdom was investigated. Read More

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Molecular identification of Scopoli, 1763 (Phthiraptera, Philopteridae) infecting the domestic pigeon from Saudi Arabia.

Saudi J Biol Sci 2021 Apr 19;28(4):2613-2617. Epub 2021 Feb 19.

Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.

The taxonomy of the order Phthiraptera is unstable and still problematic to researchers. Most of the current taxon classifications are mainly based on morphological features. belongs to the chewing lice of the Philopteridae family that mostly parasitic on birds. Read More

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The role of the anterior pretectal nucleus in pain modulation: A comprehensive review.

K Genaro W A Prado

Eur J Neurosci 2021 Apr 28. Epub 2021 Apr 28.

Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.

Descending pain modulation involves multiple encephalic sites and pathways that range from the cerebral cortex to the spinal cord. Behavioral studies conducted in the 1980s revealed that electrical stimulation of the pretectal area causes antinociception dissociation from aversive responses. Anatomical and physiological studies identified the anterior pretectal nucleus and its descending projections to several midbrain, pontine, and medullary structures. Read More

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Experimental freezing of freshwater pennate diatoms from polar habitats.

Protoplasma 2021 Apr 28. Epub 2021 Apr 28.

Department of Ecology, Faculty of Science, Charles University, Viničná 7, 128 44, Prague 2, Czech Republic.

Diatoms are microalgae that thrive in a range of habitats worldwide including polar areas. Remarkably, non-marine pennate diatoms do not create any morphologically distinct dormant stages that could help them to successfully face unfavourable conditions. Their survival is probably connected with the adaptation of vegetative cells to freezing and desiccation. Read More

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Reinstatement of Dermacentor tricuspis (Schulze, 1933) n. comb., n. stat. (Acari: Ixodidae) as a valid species, synonymization of D. atrosignatus Neumann, 1906 and description of a new species from Indonesia, Malaysia and Thailand.

Syst Parasitol 2021 Jun 23;98(3):207-230. Epub 2021 Apr 23.

Department of Biology, Faculty of Science, Mahidol University, Bangkok, Thailand.

Re-examination of the holotype of Dermacentor atrosignatus Neumann, 1906 (Acari: Ixodidae) stored in the Natural History Museum (London, UK) revealed that this taxon is identical with D. auratus Supino, 1897 and should be treated as a junior synonym of the latter species. A correct name for the distinct species previously identified as D. Read More

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sp. nov., a -like fungus from North America.

Int J Syst Evol Microbiol 2021 Apr;71(4)

The Connecticut Agricultural Experiment Station, Valley Laboratory, 153 Cook Hill Road, Windsor, CT 06095, USA.

Two isolates from Canada and the USA (UAMH 7122 and UAMH 7211, respectively) previously identified as were studied by morphology and six-locus phylogeny (, ITS, , , and ). UAMH 7122 and UAMH 7211 are morphologically related but phylogenetically distinct from (≡) and . Hence, UAMH 7122 and UAMH 7211 are described as a new species, sp. Read More

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Streptomyces brasiliscabiei, a new species causing potato scab in south Brazil.

Antonie Van Leeuwenhoek 2021 Apr 21. Epub 2021 Apr 21.

Laboratório de Bacteriologia Vegetal, Instituto Biológico, Centro Avançado em Proteção de Plantas e Sanidade Animal-CAPSA, Alameda Dos Vidoeiros, 1097, Gramado, Campinas, SP, CEP:13101-680, Brazil.

This study aimed to characterize six Streptomyces strains associated with potato scab in south Brazil through polyphasic taxonomy involving morphology, pathogenicity and genetic features. These strains were compared with other potato-scab Streptomyces species mainly S. europaeiscabiei, S. Read More

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Hidden cell diversity in Placozoa: ultrastructural insights from Hoilungia hongkongensis.

Cell Tissue Res 2021 Apr 19. Epub 2021 Apr 19.

Whitney Laboratory for Marine Bioscience, University of Florida, St. Augustine, FL, 32080, USA.

From a morphological point of view, placozoans are among the most simple free-living animals. This enigmatic phylum is critical for our understanding of the evolution of animals and their cell types. Their millimeter-sized, disc-like bodies consist of only three cell layers that are shaped by roughly seven major cell types. Read More

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Vascular anomalies of the head and neck: diagnosis and treatment.

Pediatr Radiol 2021 Apr 16. Epub 2021 Apr 16.

Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1364 Clifton Road NE, Room BG03, Atlanta, GA, 30322, USA.

Vascular malformations and vascular tumors comprise the two specific subsets of vascular anomalies that arise as a result of disorganized angiogenesis and neoplasm, respectively. Malformations are separate entities from vascular tumors (e.g. Read More

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