35,538 results match your criteria digital health


Implementation of a digital cognitive behavioral therapy for insomnia pathway in primary care.

Contemp Clin Trials 2021 Jun 12;107:106484. Epub 2021 Jun 12.

The Adelaide Institute for Sleep Health, A Centre of Research Excellence and Flinders Health and Medical Research Institute, Sleep Health, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; National Centre for Sleep Health Services Research, A NHMRC Centre of Research Excellence, Flinders University, Adelaide, South Australia, Australia.

Background Insomnia is a prevalent and debilitating disorder commonly managed by family physicians. Insomnia guidelines recommend cognitive behavioral therapy for insomnia (CBTi) as the 'first-line' treatment. However, family physicians report limited time, knowledge, access, support, and referral options to manage patients with CBTi. Read More

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A proposal for a novel approach to reduce burdens of care for people with dementia: A hypothesis.

Alzheimers Dement 2021 Jun 15. Epub 2021 Jun 15.

Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.

Cognitive impairment of dementia patients affects their ability to communicate and cooperate with care. Dementia patients need a specialized communication to increase their cooperation during daily care and a scale to measure cooperation with care. To improve communication, we created and applied a digital communication platform (DCP) in an observational study. Read More

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The effectiveness of digital self-management interventions on health outcomes among childhood cancer survivors: A systematic review and meta-analysis.

J Adv Nurs 2021 Jun 15. Epub 2021 Jun 15.

College of Nursing, Research Institute of Nursing Science, Jeonbuk National University, Jeonju, South Korea.

Aims: The study aimed to review the evidence about existing digital interventions for childhood cancer survivors and examine their effectiveness on health outcomes.

Design: Systematic review and meta-analysis.

Data Sources: PUBMED, EMBASE, Cochrane, CINAHL, Web of Science, PsycArticles, SCOPUS and PQDT Global databases were searched, and the date last searched was 16 September 2019. Read More

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A Caregiver Digital Intervention to Support Shared Decision Making in Child and Adolescent Mental Health Services: Development Process and Stakeholder Involvement Analysis.

JMIR Form Res 2021 Jun 15;5(6):e24896. Epub 2021 Jun 15.

Anna Freud National Centre for Children & Families, London, United Kingdom.

Background: Parents and caregivers are generally recognized by literature and the law as key to child and adolescent mental health decisions. Digital interventions are increasingly being used to support care and treatment in child and adolescent mental health services (CAMHS). However, evidence of the design and development process is generally not made available. Read More

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Adaptation of the World Health Organization Electronic Mental Health Gap Action Programme Intervention Guide App for Mobile Devices in Nepal and Nigeria: Protocol for a Feasibility Cluster Randomized Controlled Trial.

JMIR Res Protoc 2021 Jun 15;10(6):e24115. Epub 2021 Jun 15.

Centre for Global Mental Health, Health Service and Population Research Department, Institute of Psychology, Psychiatry & Neuroscience, King's College London, London, United Kingdom.

Background: There is a growing global need for scalable approaches to training and supervising primary care workers (PCWs) to deliver mental health services. Over the past decade, the World Health Organization Mental Health Gap Action Programme Intervention Guide (mhGAP-IG) and associated training and implementation guidance have been disseminated to more than 100 countries. On the basis of the opportunities provided by mobile technology, an updated electronic Mental Health Gap Action Programme Intervention Guide (e-mhGAP-IG) is now being developed along with a clinical dashboard and guidance for the use of mobile technology in supervision. Read More

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Preferences in digital smartphone mental health applications among adolescents: a qualitative study.

JMIR Form Res 2021 May 6. Epub 2021 May 6.

Health Service and Population Research Department, IOPPN, Kings' College London, UK, Centre for Research in Individual Differences, Department of Psychology, London, GB.

Background: Mental health digital applications (apps) hold promise to provide scalable solutions to individual self-care, education, and illness prevention. However, a problem with these apps is that they lack engaging user interfaces and experiences, potentially resulting in high attrition. While guidelines for new digital interventions in adults have begun to examine engagement, there is a paucity of evidence on how to best address digital interventions in adolescents. Read More

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MyPal: Designing and Evaluating Digital Patient-Reported Outcome Systems for Cancer Palliative Care in Europe.

J Palliat Med 2021 Jul;24(7):962-964

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.

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Digital reminiscence app co-created by people living with dementia and carers: Usability and eye gaze analysis.

Health Expect 2021 Jun 15. Epub 2021 Jun 15.

Ulster University, Newtownabbey, UK.

Background: This research reports on a pilot study that examined the usability of a reminiscence app called 'InspireD' using eye tracking technology. The InspireD app is a bespoke digital intervention aimed at supporting personalized reminiscence for people living with dementia and their carers. The app was developed and refined in two co-creation workshops and subsequently tested in a third workshop using eye tracking technology. Read More

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Botulinum toxin A (Botox) injection into muscles of pelvic floor as a treatment for persistent pelvic pain secondary to pelvic floor muscular spasm: A pilot study.

Aust N Z J Obstet Gynaecol 2021 Jun 15. Epub 2021 Jun 15.

Endosurgery Department, Mercy Hospital for Women, Melbourne, Victoria, Australia.

Background: Persistent pelvic pain (PPP) remains an important cause of morbidity. Pelvic floor muscle spasm is an important contributor to PPP.

Aims: The study's primary aim was to assess if botulinum toxin (BoNT) injection to pelvic floor muscles altered pain scores or quality of life (QoL) at six, 12 and 26 weeks. Read More

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Analyzing musculoskeletal risk prevalence among workers in developing countries: an analysis of small-scale cast-iron foundries in India.

Arch Environ Occup Health 2021 Jun 15:1-18. Epub 2021 Jun 15.

Department of Mechanical Engineering, Ch. Ranbir Singh State Institute of Engineering & Technology, Jhajjar, Haryana, India.

Musculoskeletal disorders (MSDs) are the most common health issues around the globe and a major cause of disability among workers. In developing countries, most casting industries fall under Small and Medium Scale Enterprises (SMEs); SMEs lack modern equipment and often intensively rely on manual labor. As processes are mainly labor intensive, workers employed in the metal casting sector are often at risk of MSDs. Read More

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Understanding bariatric patients' experiences of self-management post-surgery: A qualitative study.

Clin Obes 2021 Jun 14:e12473. Epub 2021 Jun 14.

Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Although most bariatric patients achieve significant weight loss and improvements in both physical and mental health-related quality of life (HRQoL) in the short-term, there is wide variability in weight and long-term HRQoL outcomes. The role of bariatric patients' self-management style in explaining variability in long-term outcomes is unclear. This qualitative study examined bariatric patients' self-management experiences after bariatric surgery in relation to long-term outcomes. Read More

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"Trapped labelled spins"-related signal on arterial spin labelling in the assessment of flow-diverted aneurysms: preliminary experience.

Neuroradiology 2021 Jun 14. Epub 2021 Jun 14.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, 560029, Karnataka, India.

Purpose: To investigate ASL-MRI features of flow-diverted aneurysms, review their haemodynamic surrogates, and discuss their pertinent clinical implications.

Methods: Retrospective single institutional analysis was performed on the clinical and imaging data of patients who underwent digital subtraction angiography (DSA) and ASL-MRI after endovascular flow diversion for cerebral aneurysms. Pseudo-continuous ASL-MRI was performed with post-label delays of 1525-1800 ms. Read More

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Novel Digital Technologies for Blood Pressure Monitoring and Hypertension Management.

Curr Cardiovasc Risk Rep 2021 9;15(8):11. Epub 2021 Jun 9.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA.

Purpose Of Review: Hypertension is common, impacting an estimated 108 million US adults, and deadly, responsible for the deaths of one in six adults annually. Optimal management includes frequent blood pressure monitoring and antihypertensive medication titration, but in the traditional office-based care delivery model, patients have their blood pressure measured only intermittently and in a way that is subject to misdiagnosis with white coat or masked hypertension. There is a growing opportunity to leverage our expanding repository of digital technology to reimagine hypertension care delivery. Read More

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Network-Based Transcriptomic Analysis Identifies the Genetic Effect of COVID-19 to Chronic Kidney Disease Patients: A Bioinformatics Approach.

Saudi J Biol Sci 2021 Jun 10. Epub 2021 Jun 10.

WHO Collaborating Centre on eHealth, UNSW Digital Health, School of Public Health and Community Medicine, Faculty of Medicine, UNSW Sydney, Australia.

COVID-19 has emerged as global health threats. Chronic kidney disease (CKD) patients are immune-compromised and may have a high risk of infection by the SARS-CoV-2. We aimed to detect common transcriptomic signatures and pathways between COVID-19 and CKD by systems biology analysis. Read More

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Reproductive risk factors of pterygium in postmenopausal women: a nationwide study in the Republic of Korea.

Sci Rep 2021 Jun 14;11(1):12473. Epub 2021 Jun 14.

Department of Family Medicine and Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

This study is to elucidate the associations between female reproductive factors and pterygium. A total of 1,339,969 postmenopausal women in a retrospective cohort of Korean National Health Insurance Service data on ages 40 and above in 2009 was included. Cox proportional hazards regression was conducted to assess the hazard ratio (HR) for pterygium according to reproductive factors. Read More

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Primary care professionals' attitudes towards digital health interventions for common mental disorders: study protocol for a mixed methods systematic review.

BMJ Open 2021 06 14;11(6):e045657. Epub 2021 Jun 14.

Institute of General Practice, University of Frankfurt, Frankfurt am Main, Germany

Introduction: Mental disorders such as depression are common, and an estimated 264 million people are affected by them throughout the world. In recent years, studies on digital health interventions to treat mental disorders have shown evidence of their efficacy, and interest in using them has increased as a result. In the primary care setting, depression and anxiety are the two most frequently diagnosed and treated mental disorders. Read More

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Evaluation of test characteristics of 2 ELISA tests applied to bulk tank milk and claw-trimming records for herd-level diagnosis of bovine digital dermatitis using latent class analysis.

J Dairy Sci 2021 Jun 11. Epub 2021 Jun 11.

Department of Production Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, PO Box 369 Sentrum, N-0102 Oslo, Norway.

Bovine digital dermatitis (DD) is an infectious claw disease with a negative effect on animal welfare and production. Treponema spp. is the main causative agent, and infected animals produce specific antibodies. Read More

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Psychiatric Prescriber Attitudes, Experiences, and Proclivities Toward Digital Medicine and How They Influence Adoption of Digital Medicine Platforms.

CNS Spectr 2021 Apr;26(2):144-145

Otsuka Pharmaceutical Development & Commercialization, Inc., Princeton, NJ, USA.

Background: Psychiatric prescribers typically assess adherence by patient or caregiver self-report. A new digital medicine (DM) technology provides objective data on adherence by using an ingestible event monitoring (IEM) sensor embedded within oral medication to track ingestion. Despite likely clinical benefit, adoption by prescribers will in part depend on attitudes toward and experience with digital health technology, learning style preference (LSP), and how the technology s utility and value are described. Read More

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Differential effects of risk factors on the cognitive trajectory of early- and late-onset Alzheimer's disease.

Alzheimers Res Ther 2021 Jun 14;13(1):113. Epub 2021 Jun 14.

Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: Although few studies have shown that risk factors for Alzheimer's disease (AD) are associated with cognitive decline in AD, not much is known whether the impact of risk factors differs between early-onset AD (EOAD, symptom onset < 65 years of age) versus late-onset AD (LOAD). Therefore, we evaluated whether the impact of Alzheimer's disease (AD) risk factors on cognitive trajectories differ in EOAD and LOAD.

Methods: We followed-up 193 EOAD and 476 LOAD patients without known autosomal dominant AD mutation for 32. Read More

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GPS driving: a digital biomarker for preclinical Alzheimer disease.

Alzheimers Res Ther 2021 Jun 14;13(1):115. Epub 2021 Jun 14.

Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.

Background: Alzheimer disease (AD) is the most common cause of dementia. Preclinical AD is the period during which early AD brain changes are present but cognitive symptoms have not yet manifest. The presence of AD brain changes can be ascertained by molecular biomarkers obtained via imaging and lumbar puncture. Read More

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Vulnerability of personality disorder during the Covid-19 crises - a multicenter survey of treatment experiences among patients referred to treatment.

Nord J Psychiatry 2021 Jun 14:1-12. Epub 2021 Jun 14.

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Background: The societal shutdown due to the Covid-19 pandemic involved mental health services for personality disorder (PD) and was introduced from 12 March 2020 in Norway. Rapid implementation of treatment modifications was required for patients typically characterized by insecure attachment and vulnerability to separation.

Aim: To investigate immediate reactions to the shutdown of services; alternative treatment received; and differences related to age in a clinical sample of patients with PD. Read More

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COVID-19 vaccine delivery: an opportunity to set up systems for the future.

Gates Open Res 2020 14;4:182. Epub 2021 Apr 14.

School of Medicine, Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, Ca, 92093, USA.

The race to develop safe and effective SARS-COV-2 vaccines has moved with unprecedented speed. There are now multiple vaccines that have received emergency use authorization from the United States Food and Drug Administration and a host of candidates positioned for approval worldwide. Attention has now turned to allocation, distribution and verification of these vaccines, yet this focus exposes that the underlying infrastructure for global delivery and monitoring is threadbare and unevenly distributed. Read More

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Significant difference in response of malignant tumor cells of individual patients to photodynamic treatment as revealed by digital holographic microscopy.

J Photochem Photobiol B 2021 Jun 3;221:112235. Epub 2021 Jun 3.

Ioffe Institute, Russian Academy of Sciences, St. Petersburg, Russia.

The investigation of in-vitro response of cell cultures derived from tumor material of individual patients with similar tumor localizations to photodynamic treatment is presented. Tumor types included in the research were renal cell carcinoma, melanoma and alveolar, synovial, lypo- and osteo- sarcomas. Long-term observations of treatment-induced morphological changes in cells were performed by means of digital holographic microscopy. Read More

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Expectations about pain and analgesic treatment are shaped by medical providers' facial appearances: Evidence from five online clinical simulation experiments.

Soc Sci Med 2021 Jun 3;281:114091. Epub 2021 Jun 3.

National Center for Complementary and Integrative Health, National Institute of Health, Bethesda, MD, 20892, USA; National Institute of Mental Health, National Institute of Health, Bethesda, MD, 20892, USA; National Institute on Drug Abuse, National Institute of Health, Baltimore, MD, 21224, USA. Electronic address:

Rationale: There is a robust link between patients' expectations and clinical outcomes, as evidenced by the placebo effect. Expectations depend in large part on the context surrounding treatment, including the patient-provider interaction. Prior work indicates that providers' behavior and characteristics, including warmth and competence, can shape patient outcomes. Read More

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Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids.

Cancer Lett 2021 Jun 11. Epub 2021 Jun 11.

Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, USA. Electronic address:

Tumors evade immune surveillance by expressing Programmed Death-Ligand 1 (PD-L1), subsequently inhibiting CD8 cytotoxic T lymphocyte function. Response of gastric cancer to immunotherapy is relatively low. Our laboratory has reported that Helicobacter pylori-induced PD-L1 expression within the gastric epithelium is mediated by the Hedgehog (Hh) signaling pathway. Read More

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Standing on the shoulders of giants: A decade of research on digital pediatric sleep interventions.

Pediatr Pulmonol 2021 Jun 14. Epub 2021 Jun 14.

Division of Pulmonary and Sleep Medicine, Sleep Center, Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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Fragmentation in the future of work: A horizon scan examining the impact of the changing nature of work on workers experiencing vulnerability.

Am J Ind Med 2021 Jun 14. Epub 2021 Jun 14.

Institute for Work and Health, Toronto, Ontario, Canada.

Introduction: The future of work is characterized by changes that could disrupt all aspects of the nature and availability of work. Our study aims to understand how the future of work could result in conditions, which contribute to vulnerability for different groups of workers.

Methods: A horizon scan was conducted to systematically identify and synthesize diverse sources of evidence, including academic and gray literature and resources shared over social media. Read More

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Root canal pre-treatment and adhesive system affect bond strength durability of fiber posts ex vivo.

Clin Oral Investig 2021 Jun 14. Epub 2021 Jun 14.

Department of Operative and Preventive Dentistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Berlin, Germany.

Objectives: To investigate the effect of different pre-treatments on the long-term bond strength of fiberglass posts luted either with dual-curing self-etch adhesives and core build-up composites or with a self-adhesive resin (SAR) cement.

Materials And Methods: In total, 180 human root-filled teeth received post-space preparations and three different dentin pre-treatments (PTs): PT1, ethanol (99%); PT2, ethanol-tertiary-butanol-water-solution (AH Plus Cleaner, Dentsply Sirona; York, USA); and PT3, distilled water (control). Five luting systems were used: FU, Futurabond U (Voco; Cuxhaven, Germany); CL, Clearfil DC Bond (Kuraray Noritake; Okayama, Japan); GR, Gradia Core SE Bond (GC Europe NV; Leuven, Belgium); LU, LuxaBond Universal (DMG; Hamburg, Germany); and RX, RelyX Unicem 2 (3M; Minnesota, USA). Read More

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Epidemiology of glucocorticoid-induced osteoporosis and management of associated fracture risk in Japan.

J Bone Miner Metab 2021 Jun 14. Epub 2021 Jun 14.

Primary Medical Science Department, Medical Affairs Division, Japan Business Unit, Daiichi Sankyo Co. Ltd, 3-5-1, Nihonbashi Honcho, Chuo-ku, Tokyo, Japan.

Introduction: Glucocorticoid-induced osteoporosis (GIOP) is associated with a high fracture risk. Practice guidelines by the Japanese Society for Bone and Mineral Research in 2014 recommend bone densitometry and appropriate treatment to reduce this risk. The study objectives were to describe characteristics of GIOP patients in Japan and to evaluate their management in a subgroup of patients without comorbid cancer. Read More

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